*  Bioinformatics biologists | Genomics, bioinformatics and systems biology | Cambridge University Press

2. Pattern identification in a haplotype block Kun-Mao Chao. 3. Genome reconstruction: a puzzle with a billion pieces Phillip ...
cambridge.org/us/academic/subjects/life-sciences/genomics-bioinformatics-and-systems-biology/bioinformatics-biologists?format=PB&isbn=9781107648876

*  ABCC2 ATP binding cassette subfamily C member 2 [Homo sapiens (human)] - Gene - NCBI

Haplotyping and founder effect of deletion in ABCC2.. * Resveratrol-3-O-sulfate reduced in both MRP2-overexpressing MDCKII- ...
https://ncbi.nlm.nih.gov/gene/1244

*  Plus it

KRAS was the only gene with two haplotype blocks, the other genes had only one haplotype block. Haplotypes with a frequency of ... We also found associations with clinical outcome for haplotypes in BRAF and KRAS. The association with the haplotype in BRAF ... We found no association for haplotypes in the NMI, ERBB2, and PIK3CA genes. In BRAF, the h32342344 haplotype was associated ... We found evidence of association with survival in patients with ovarian cancer for a single tSNP and a haplotype in the BRAF ...
clincancerres.aacrjournals.org/content/14/18/5833

*  Drive and sperm competition in mice | Proceedings of the Royal Society of London B: Biological Sciences

The t haplotype in house mice is a very intensively studied SGE [5]. Typically, t haplotypes are inherited by 90% of the ... Thus, the t haplotype's 'antidote' does not appear to provide full protection from the t haplotype's own 'poisonous' effect. ... t haplotype status was diagnosed by PCR [28,37]. Male mice were separated latest at the onset of aggression between brothers ... If t haplotype drive is achieved by harming +sperm alone, then the 90% drive observed in our study population should reflect a ...
rspb.royalsocietypublishing.org/content/282/1811/20150974

*  The Modifier of hemostasis (Mh) locus on chromosome 4 controls in vivo hemostasis of Gp6−/− mice | Blood Journal

B) Haplotype diagram of chromosome 4. This diagram schematically depicts the haplotypes for the 44 Gp6−/− LONG (LEFT).and 34 ... At this locus, the 129 × 1/SvJ haplotype predominates in Gp6−/− SHORT mice, whereas the C57 BL/6J haplotype is more often ... Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse. Proc Natl Acad Sci U S A 2003;100:3380 ... This diagram schematically depicts the haplotypes for representative number of mice: 14 Gp6−/− SHORT and 22 Gp6−/− LONG. Each ...
bloodjournal.org/content/111/3/1266.full?sso-checked=true

*  PPT - Toward the Ecological Genomics Underlying Plant Adaptation PowerPoint Presentation - ID:1345568

common haplotypes 149 Non singleton SNPs ,6000 accessions Global, Midwest, and UK ...
slideserve.com/payton/toward-the-ecological-genomics-underlying-plant-adaptation-1345568

*  CYP1B1 cytochrome P450 family 1 subfamily B member 1 [Homo sapiens (human)] - Gene - NCBI

CYP1B1 haplotypes could be more effective in predicting Head and Neck Squamous Cell Carcinoma risk. Title: Association of ... Association of cytochrome P450 1B1 haplotypes with head and neck cancer risk. Katiyar T, et al. Environ Mol Mutagen, 2017 Jul. ...
https://ncbi.nlm.nih.gov/gene/1545

*  Methods and apparatus for freezing tissue - MORRIS GEORGE J.

Haplotype map of the human genome and uses therefor. September, 2003. Daly et al. ...
freepatentsonline.com/y2004/0053204.html

*  Biologic and Genetics Aspects of Chagas Disease at Endemic Areas : Table 1

Haplotype +80 C +252 G associated to CCC susceptibility. [28] TLR. TLR1 TLR2 TLR4 TLR5 TLR9. Pathogen recognition receptors. ...
https://hindawi.com/journals/jtm/2012/357948/tab1/

*  Goal 2 - Individual Susceptibility Across the Lifespan

Association of Nrf2 polymorphism haplotypes with acute lung injury phenotypes in inbred strains of mice. Cho, HY (DIR), ...
https://niehs.nih.gov/about/strategicplan/implementation/goal2/index.cfm

*  Dienekes' Anthropology Blog: 06/2005

Y-chromosome variation data obtained in the present study demonstrate that the Russian gene pool appears to be close to central-eastern European populations. The data show a high frequency of haplogroups R1a and N3. The high incidence of R1a haplotypes in Eastern Slavs and in Baltic and some Finno-Ugric populations of eastern Europe is a well-established fact (Rosser et al. 2000; Wells et al. 2001; Zerjal et al. 2001), but little is known about the spread of haplogroup N3 in different Russian populations. Our data indicate that this haplogroup is unevenly distributed in Russian populations, with frequencies ranging from 4.8% to 35%. It is noteworthy that in most of the populations studied (with the exception of the Pskov sample) the frequency of haplogroup N3 does not exceed 20%. An important feature distinguishing Russians from their eastern European neighbors is almost complete absence of paragroup N*, which is ancestral to haplogroup N3. In Europe the highest frequencies of paragroup N* ...
dienekes.blogspot.gr/2005/06/

*  Rainfall-driven sex-ratio genes in African buffalo suggested by correlations between Y-chromosomal haplotype frequencies and...

Rainfall-driven sex-ratio genes in African buffalo suggested by correlations between Y-chromosomal haplotype frequencies and foetal sex ratio ...
vetmed.oregonstate.edu/publications/rainfall-driven-sex-ratio-genes-african-buffalo-suggested-correlations-between-y-chromo

*  Evidence of a long QT founder gene with varying phenotypic expression in South African families. | Journal of Medical Genetics

We report five South African families of northern European descent (pedigrees 161, 162, 163, 164, and 166) in whom Romano-Ward long QT syndrome (LQT) segregates. The disease mapped to a group of linked markers on chromosome 11p15.5, with maximum combined two point lod scores, all generated at theta = 0, of 15.43 for the D11S922, 10.51 for the D11S1318, and 14.29 for the tyrosine hydroxylase (TH) loci. Recent studies have shown that LQT is caused by an Ala212Val mutation in a potassium channel gene (KVLQT1) in pedigrees 161 to 164. We report that the same mutation is responsible for the disease in pedigree 166. Haplotype construction showed that all the families shared a common haplotype, suggesting a founder gene effect. DNA based identification of gene carriers allowed assessment of the clinical spectrum of LQT. The QTc interval was significantly shorter in both carriers and non-carriers in pedigree 161 (0.48 s and 0.39 s, respectively) than the same two groups in pedigree 161 (0.52 s and 0.42 ...
jmg.bmj.com/content/33/7/567

*  Contribution of Clinical Correlates and 13 C-Reactive Protein Gene Polymorphisms to Interindividual Variability in Serum C...

Several prior studies have examined the relations between CRP polymorphisms and CRP levels and reported individual associations between rs1800947 (also referred to as 1059 G/C),27 rs1130864 (+1444C→T),17 rs1205,28 rs1417938,16 rs3091244,2,18,29,30 and CRP level. With regard to CRP SNPs and CVD end points, Zee and Ridker27 reported that rs1800947 was not associated with a composite end point of nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death, whereas Chen et al31 found that among Han Chinese, there was an association between a CRP SNP (rs2794521) and coronary heart disease.. Until recently, it was not clear whether the reported SNP-CRP level associations represented several distinct independent SNP associations or multiple associations due to LD. Carlson et al2 addressed this issue by evaluating 7 tag SNPs in the 6.8 kb surrounding the CRP gene and demonstrated that in individuals of European ancestry, 2 specific haplotypes were associated with higher CRP levels.. We ...
circ.ahajournals.org/content/113/11/1415

*  Genetic Chaos

High-resolution Y-chromosome haplogroup analyses coupled with Y-short tandem repeat (STR) haplotypes were used to (1) investigate the genetic affinities of three populations from Nepal-including Newar, Tamang, and people from cosmopolitan Kathmandu (referred to as "Kathmandu" subsequently)-as well as a collection from Tibet and (2) evaluate whether the Himalayan mountain range represents a geographic barrier for gene flow between the Tibetan plateau and the South Asian subcontinent. The results suggest that the Tibetans and Nepalese are in part descendants of Tibeto-Burman-speaking groups originating from Northeast Asia. All four populations are represented predominantly by haplogroup O3a5-M134-derived chromosomes, whose Y-STR-based age (±SE) was estimated at 8.1 ± 2.9 thousand years ago (KYA), more recent than its Southeast Asian counterpart. The most pronounced difference between the two regions is reflected in the opposing high-frequency distributions of haplogroups D in Tibet and R in ...
vetinarilord.blogspot.com/2005/04/y-chromosome-haplotypes-reveal.html

*  Nancy Cox « People « Institute for Genomics and Systems Biology

My laboratory is a computational "dry" lab. Our research focus is on the identification and characterization of genetic variation influencing susceptibility to complex disorders. We work on both the localization of the genetic variation, via linkage studies and linkage disequilibrium mapping, as well as on the analytic component to positional cloning of genes for complex disorders. There are ongoing collaborations with a variety of groups at the University of Chicago for which we contribute the genetic analysis, including both linkage and linkage disequilibrium mapping, and these include projects on type 1 and type 2 diabetes, asthma and related phenotypes, attention deficit hyperactivity disorder, schizophrenia, bipolar disorder, and autism. In addition, we have a primary focus on developing and extending methods for mapping genes for complex disorders. Currently, this research includes an emphasis on developing robust methods for taking gene-gene interaction into account in the context of ...
igsb.org/people/nancy-cox

*  The minimum number of cord blood units needed for Koreans is 51,000 - Yoon - 2013 - Transfusion - Wiley Online Library

Table S1. HLA-A, -B and -DRB1 allele frequencies and antigenic specificities for HLA-B locus in Korean cord blood units (n = 17,508). Table S2. Two-locus (A-B and B-DRB1) HLA haplotype frequencies (HF) of Korean CBUs along with linkage disequilibrium (HF ≥ 0.50%, χ2 , 10.752 for HLA-A and HLA-B, χ2 , 11.103 for HLA-B and HLA-DRB1). Table S3. HLA-A, B, DRB1 three-locus haplotype frequency (HF) in 17,508 Korean newborn (HF ≥ 0.1%). ...
onlinelibrary.wiley.com/doi/10.1111/trf.12284/abstract

*  NGS-resources: A method for identifying haplotypes carrying the causative allele in positive natural selection and genome-wide...

Results: We present HapFinder, a method which can find the common longest haplotype under three different settings from a database, which is relevant in the analysis of positive selection in population genetics and also in medical genetics for finding the likely haplotype form carrying the causal allele at the functional polymorphism. ...
ngs-resources.blogspot.com/2011/01/method-for-identifying-haplotypes_09.html

*  Plus it

Haplotype Analysis. The haplotypes regarding novel and known nonsynonymous variations were analyzed. K401R and N487D were found as single heterozygous SNPs. K17T or I514T was found together with a known variation, R554K, in the same subject. To determine a linkage between these variations, the amplified genomic fragments from the subjects were cloned into the pENTR/D-TOPO vector (Invitrogen., Carlsbad, CA) and sequenced with an ABI Big Dye Terminator Cycle Sequencing kit (Applied Biosystems, Foster City, CA) and ABI Prism 3730 DNA analyzer (Applied Biosystems). The linkage between K17T and R554K was determined by linkage between K17T and -742C→T that was linked with R554K. To determine the linkage between I514T and R554K, the genomic fragments containing the codons 514 and 554 were sequenced. Ethical review boards of the National Cancer Center and the National Institute of Health Sciences approved this study.. Plasmids. hAhR cDNA was cloned into the pcDNA3.2-DEST vector (Invitrogen), and the ...
dmd.aspetjournals.org/content/33/8/1254

*  Single Nucleotide Polymorphisms: Methods and Protocols

Finden Sie alle Bücher von Williford, Carolyn T.; Kwok, Pui-Yan - Single Nucleotide Polymorphisms: Methods and Protocols. Bei der Büchersuchmaschine eurobuch.com können Sie antiquarische und Neubücher VERGLEICHEN UND SOFORT zum Bestpreis bestellen. 0896039684
https://eurobuch.com/buch/isbn/0896039684.html

*  Publications | Baker Lab

Kuang H, Wei F, Marano M R, Wirtz U, Wang X, Liu J, Shum W P, Zaborsky J, Tallon LJ, Rensink W et al.. 2005. The R1 resistance gene cluster contains three groups of independently evolving, type I R1 homologues and shows substantial structural variation among haplotypes of Solanum demissum. The Plant journal : for cell and molecular biology. 44(1):37-51. ...
bakerlab.berkeley.edu/publications

*  Publications | Baker Lab

Kuang H, Wei F, Marano M R, Wirtz U, Wang X, Liu J, Shum W P, Zaborsky J, Tallon LJ, Rensink W et al.. 2005. The R1 resistance gene cluster contains three groups of independently evolving, type I R1 homologues and shows substantial structural variation among haplotypes of Solanum demissum. The Plant journal : for cell and molecular biology. 44(1):37-51. ...
bakerlab.berkeley.edu/publications/

*  FCN3抗体|Abcam中国|Anti-FCN3抗体(ab98136)

FCN3兔多克隆抗体(ab98136)可与人样本反应并经WB实验严格验证。中国75%以上现货,所有产品均提供质保服务,可通过电话、电邮或微信获得本地专属技术支持。
abcam.cn/fcn3-antibody-ab98136.html