HLA-B39 - Wikipedia
HLA-B39 (B39) is an HLA-B serotype. The serotype identifies the more common HLA-B*39 gene products. B39 is a split antigen of ... Psoriatic arthritis appears to be linked to MICA-A9 which tightly linked to HLA-B39. B39 also appears to be involved in the ... Genetics and HLA antigens". Baillières Clinical Rheumatology. 8 (2): 263-76. doi:10.1016/S0950-3579(94)80018-9. PMID 8076387. ... Sobao Y, Tsuchiya N, Takiguchi M, Tokunaga K (January 1999). "Overlapping peptide-binding specificities of HLA-B27 and B39: ...
Psoriatic arthritis: epidemiology, clinical features, course, and outcome | Annals of the Rheumatic Diseases
HLA-B22 was protective; HLA-B27 in the presence of HLA-DR7, HLA-B39, and HLA-DQw3 in the absence of HLA-DR7, were predictive of ... Gladman DD, Anhorn KA, Schachter RK, Mervart H. HLA antigens in psoriatic arthritis. J Rheumatol1986;13:586-92. ... PsA has been associated with human leucocyte antigen (HLA) class 1 alleles as opposed to the class 2 alleles associated with RA ... HLA antigens and progression in psoriatic arthritis. J Rheumatol1998;25:730-3. ...
Psoriatic Arthritis Imaging: Practice Essentials, Radiography, Computed Tomography
HLA) alleles, including HLA-B13, HLA-B17, HLA-B27, HLA-B38, HLA-B39, HLA-Cw6, HLA-DR4, and HLA-DR7. HLA-B27 is present in 60% ... A haplotype epidemiologic association with PA involves the expression of both class I and class II human leukocyte antigen ( ...
"HLA Alleles in Mexican Mestizos . . ." by Claudia De Leo, Natalia Castelan et al.
The predominant antigens in decreasing order of frequency were B35, B39, and B61 at the B locus; DR4, DR5, and DR8 at the DR ... The most common HLA-B,HLA-DR haplotype (considering broad specificities) was B16,DR4, with a frequency of 8.0%. Five HLA-B,HLA- ... The study includes HLA-B typing and its association with the HLA-DR antigens determined in 50 families, which included 100 ... On the other hand, the most common HLA-DR,HLA-DQ haplotypes were DR4,DQ3 and DR5,DQ3 with a frequency higher than 10%. Ten of ...
Improved murine MHC-deficient HLA transgenic NOD mouse models for type 1 diabetes therapy development<...
HLA-B39 Antigen Medicine & Life Sciences 32% * T-Lymphocytes Medicine & Life Sciences 30% ... Transgenic expression of HLA-A2 or-B39 restored pathogenic CD8+ T-cell development and T1D susceptibility to NOD-cMHCI-/- mice ... Transgenic expression of HLA-A2 or-B39 restored pathogenic CD8+ T-cell development and T1D susceptibility to NOD-cMHCI-/- mice ... Transgenic expression of HLA-A2 or-B39 restored pathogenic CD8+ T-cell development and T1D susceptibility to NOD-cMHCI-/- mice ...
Psoriatic Arthritis - Musculoskeletal and Connective Tissue Disorders - MSD Manual Professional Edition
HLA-B27) or some other specific alleles (HLA-Cw6, HLA-B38, HLA-B39, HLA-DR) in family members. Etiology and pathophysiology of ... Abatacept is a soluble fusion cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) Ig. It is available for adults with active ... Axial involvement may be present, especially in male patients with positive HLA-B27, and usually manifests as asymmetric ... Risk is increased in patients with human leukocyte antigen B27 ( ...
Analysis of Single Nucleotide Polymorphisms Identifies Major Type 1A Diabetes Locus Telomeric of the Major Histocompatibility...
OBJECTIVE-HLA-DRB1*03-DQB1*0201/DRB1*04-DQB1*0302 (DR3/4-DQ8) siblings who share both major histocompatibility complex (MHC) ... We completed a stepwise logistic regression analysis by analyzing HLA-DRB1, HLA-DQB1, HLA-B39, HLA-A24, and rs1233478 as ... They are also involved in regulation of members of the immunoreceptor family, including B-cell antigen receptors (32). The UBD ... HLA-DQB1, HLA-B, HLA-A, and rs1233478 as explanatory variables. The final model included HLA-DRB1, HLA-DQB1, HLA-B, and ...
Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction | BMC Bioinformatics | Full Text
In the large-scale benchmark calculation consisting of 216 known HIV epitopes covering all 12 recognized HLA supertypes, the ... The updated version of NetCTL, version 1.2, can make predictions for the A26 and B39 HLA supertypes thus completing the list of ... Smith KD, Lutz CT: Peptide-dependent expression of HLA-B7 on antigen processing-deficient T2 cells. J Immunol 1996, 156(10): ... The method is available at [43] and includes predictions for HLA-A*01, HLA-A*0201, HLA-A*03, and HLA-B*2705. Table 3 shows ...
Dolly B. Tyan, PhD's Profile | Stanford Profiles
HLA-B16 ANTIGENS - SEQUENCE OF THE ST-16 ANTIGEN, FURTHER DEFINITION OF 2 B38 SUBTYPES AND EVIDENCE FOR CONVERGENT EVOLUTION OF ... The ST-16 antigenic specificity of the HLA-B locus is defined as a B39 variant of Mexican-Americans. Nucleotide sequencing of ... Epitopes are distinct regions on an antigen to which antibody can be elicited and bound. However, for HLA antigens, there is no ... The high degree of polymorphism at human leukocyte antigen (HLA) class I and class II loci makes high-resolution HLA typing ...
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D12.776.543.550.439.500.370 HLA-B38 Antigen D12.776.543.550.421.500.380 D12.776.543.550.439.500.380 HLA-B39 Antigen D12.776. ... HLA-DR1 Antigen D12.776.543.550.423.400.440.400.10 D12.776.543.550.440.400.440.400.10 HLA-DR2 Antigen D12.776.543.550.423.400. ... HLA-DR3 Antigen D12.776.543.550.423.400.440.400.30 D12.776.543.550.440.400.440.400.30 HLA-DR4 Antigen D12.776.543.550.423.400. ... HLA-DR5 Antigen D12.776.543.550.423.400.440.400.50 D12.776.543.550.440.400.440.400.50 HLA-DR6 Antigen D12.776.543.550.423.400. ...
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D12.776.543.550.439.500.370 HLA-B38 Antigen D12.776.543.550.421.500.380 D12.776.543.550.439.500.380 HLA-B39 Antigen D12.776. ... HLA-DR1 Antigen D12.776.543.550.423.400.440.400.10 D12.776.543.550.440.400.440.400.10 HLA-DR2 Antigen D12.776.543.550.423.400. ... HLA-DR3 Antigen D12.776.543.550.423.400.440.400.30 D12.776.543.550.440.400.440.400.30 HLA-DR4 Antigen D12.776.543.550.423.400. ... HLA-DR5 Antigen D12.776.543.550.423.400.440.400.50 D12.776.543.550.440.400.440.400.50 HLA-DR6 Antigen D12.776.543.550.423.400. ...
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D12.776.543.550.439.500.370 HLA-B38 Antigen D12.776.543.550.421.500.380 D12.776.543.550.439.500.380 HLA-B39 Antigen D12.776. ... HLA-DR1 Antigen D12.776.543.550.423.400.440.400.10 D12.776.543.550.440.400.440.400.10 HLA-DR2 Antigen D12.776.543.550.423.400. ... HLA-DR3 Antigen D12.776.543.550.423.400.440.400.30 D12.776.543.550.440.400.440.400.30 HLA-DR4 Antigen D12.776.543.550.423.400. ... HLA-DR5 Antigen D12.776.543.550.423.400.440.400.50 D12.776.543.550.440.400.440.400.50 HLA-DR6 Antigen D12.776.543.550.423.400. ...
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D12.776.543.550.439.500.370 HLA-B38 Antigen D12.776.543.550.421.500.380 D12.776.543.550.439.500.380 HLA-B39 Antigen D12.776. ... HLA-DR1 Antigen D12.776.543.550.423.400.440.400.10 D12.776.543.550.440.400.440.400.10 HLA-DR2 Antigen D12.776.543.550.423.400. ... HLA-DR3 Antigen D12.776.543.550.423.400.440.400.30 D12.776.543.550.440.400.440.400.30 HLA-DR4 Antigen D12.776.543.550.423.400. ... HLA-DR5 Antigen D12.776.543.550.423.400.440.400.50 D12.776.543.550.440.400.440.400.50 HLA-DR6 Antigen D12.776.543.550.423.400. ...
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D12.776.543.550.439.500.370 HLA-B38 Antigen D12.776.543.550.421.500.380 D12.776.543.550.439.500.380 HLA-B39 Antigen D12.776. ... HLA-DR1 Antigen D12.776.543.550.423.400.440.400.10 D12.776.543.550.440.400.440.400.10 HLA-DR2 Antigen D12.776.543.550.423.400. ... HLA-DR3 Antigen D12.776.543.550.423.400.440.400.30 D12.776.543.550.440.400.440.400.30 HLA-DR4 Antigen D12.776.543.550.423.400. ... HLA-DR5 Antigen D12.776.543.550.423.400.440.400.50 D12.776.543.550.440.400.440.400.50 HLA-DR6 Antigen D12.776.543.550.423.400. ...
Polyarteritis Nodosa: Background, Pathophysiology, Etiology
21] Cutaneous PAN occurring with HLA-B39 spondyloarthritis, [22] common variable immunodeficiency, [23] and psoriatic arthritis ... Presence of hepatitis B surface antigen or antibody in serum. * Arteriogram demonstrating aneurysms or occlusions of the ... Cutaneous polyarteritis nodosa associated with HLA-B39-positive undifferentiated spondyloarthritis in a Japanese patient. Mod ...
An immunoinformatics approach to epitope-based vaccine design against PspA in Streptococcus pneumoniae | Journal of Genetic...
Molecular docking, molecular dynamic simulation, and immune simulation were performed to ensure the binding between HLA and ... Due to its capability to produce antibodies that interact with antigens, B-cell epitope identification in target antigens has ... To ensure the binding between HLA molecules TLR4 and our predicted vaccine, a docking study was performed using ClusPro 2.0 ( ... B39, B44, B58, and B62) of MHC class 1, only A1 supertype was selected within the NetCTL parameters. The identified epitopes ...
Can Cathepsin L Epitope Be an Effective Vaccine Candidate Against Fasciola gigantica via Bioinformatics? | Annals of Military...
HLA-A02:01, HLA-A26:01, HLA-B27:05, and HLA-B39:01 as human MHC class I molecules and 5-allele HLA reference set including DRB1 ... Antigen mimicry, epitope spreading and the pathogenesis of pemphigus. Tissue Antigens. 2006;68(4):280-6. [PubMed ID: 17026461 ... NetMHCIIpan is applied to predict human MHC class II isotypes, including HLA-DR, HLA-DP, HLA-DQ, and mouse molecules (H-2) (19 ... The epitope is part of the antigen, detected by B-cell and T-cell molecules of the mammalian immune system. Only a few amino ...
Pesquisa | Portal Regional da BVS
HLA-B27 in AS, HLA-B39 and HLA-Cw6 in r-axPsA, and HLA-Cw7 in nr-axPsA. Important conclusions about the nr-axPsA group cannot ... 2)700 UC patients developed AS during follow-up (1.66%, 95% CI: 0.89-2.62%). Human leukocyte antigen B27 (HLA-B27) was reported ... HLA-DR16 in AS, HLA-DR11 in nr-axSpA, HLA-B13, HLA-B57, HLA-Cw12 and HLA-DR7 in r-axPsA, and HLA-B18 in nr-axPsA. Our study ... HLA-B27 positivity was significantly higher than the incidence of HLA-B27 negativity in AS patients (68.29% vs 31.71%, P < ...
Genetic Basis of PsA
Psoriasis was found to be associated with HLA class I antigens, specifically HLA-Cw6, and with several HLA-B alleles. HLA ... These include B27, B7, B38, and B39. B27 is associated with more spinal involvement, while B38 and B39 are associated with ... Through association studies, several human leukocyte antigen (HLA) alleles have been found to be associated with psoriasis and ...
Studies on the human leukocyte antigens in patients with polycystic ovary syndrome in a Japanese population--possible...
Human leukocyte antigen systems appear to be linked to PCOS. ... The rate of possession of HLA-B39 in the patients with PCOS was ... Method of study: HLA-A, -B and -C antigens were determined in 56 patients with PCOS using conventional serological method. HLA- ... C antigens, and 292 individuals were examined concerning HLA-DRB1 genotypes. The rate of possession of each antigen was ... Problem: The objective of this study was to identify the human leukocyte antigen (HLA) alleles that confer susceptibility or ...
MeSH Browser
HLA B39 HLA Class I Histocompatibility Antigen, B-39 alpha Chain HLA-B39 Registry Number. 0. Public MeSH Note. 2012; HLA-B39 ... HLA Antigens [D23.050.301.500.450] * HLA-B Antigens [D23.050.301.500.450.380] * HLA-B7 Antigen [D23.050.301.500.450.380.070] ... HLA Antigens [D23.050.705.552.450] * HLA-B Antigens [D23.050.705.552.450.380] * HLA-B7 Antigen [D23.050.705.552.450.380.070] ... HLA-B39 Antigen Preferred Concept UI. M0552024. Registry Number. 0. Scope Note. A specific HLA-B surface antigen subtype. ...
MeSH Browser
HLA B39 HLA Class I Histocompatibility Antigen, B-39 alpha Chain HLA-B39 Registry Number. 0. Public MeSH Note. 2012; HLA-B39 ... HLA Antigens [D23.050.301.500.450] * HLA-B Antigens [D23.050.301.500.450.380] * HLA-B7 Antigen [D23.050.301.500.450.380.070] ... HLA Antigens [D23.050.705.552.450] * HLA-B Antigens [D23.050.705.552.450.380] * HLA-B7 Antigen [D23.050.705.552.450.380.070] ... HLA-B39 Antigen Preferred Concept UI. M0552024. Registry Number. 0. Scope Note. A specific HLA-B surface antigen subtype. ...
WHO EMRO | Major histocompatibility class I antigens in the Lebanese population | Volume 3, issue 1 | EMHJ volume 3, 1997
... antigens in the Lebanese population. We describe the frequency and distribution of MHC class I antigens present in the A, B and ... HLA antigens of four different North American ethnic groups. In: Kissmeyer-Nielsen F, ed. Histocompatibility testing. ... B39), which in these patients exhibited an odds ratio of 9.6 [14]. ... HLA antigens in the Arab population of the Gaza strip. Israeli medical journal, 1979, 15:14-6. ...
Teresa P. DiLorenzo - Publications - Albert Einstein College of Medicine
Multiple antigens versus single major antigen in type 1 diabetes: Arguing for multiple antigens. Dilorenzo, T. P., Nov 2011, In ... Beyond HLA-A*0201: New HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a ... Lieberman, S. M. & DiLorenzo, T. P., Nov 2003, In: Tissue Antigens. 62, 5, p. 359-377 19 p.. Research output: Contribution to ... HLA class I supertypes in type 1 diabetic children in an urban childrens hospital. Antal, Z., Jarchum, I. & DiLorenzo, T. P., ...
Code System Concept
Human leukocyte antigen HLA-B39 antigen Current Synonym true false 2621290019 Human leucocyte antigen HLA-B39 antigen Current ... Human leukocyte antigen B antigen (substance) {54481006 , SNOMED-CT } Human leukocyte antigen class I type antigen A1 - B57 ( ... HLA-B39 antigen Current Synonym true false 2621289011 ... Human leukocyte antigen B39 Current Synonym true false ... Human leukocyte antigen B39 (substance). Code System Preferred Concept Name. Human leukocyte antigen B39 (substance). ...
Genetic Basis of PsA
Psoriasis was found to be associated with HLA class I antigens, specifically HLA-Cw6, and with several HLA-B alleles. HLA ... These include B27, B7, B38, and B39. B27 is associated with more spinal involvement, while B38 and B39 are associated with ... Through association studies, several human leukocyte antigen (HLA) alleles have been found to be associated with psoriasis and ...
NEW (2012) MESH HEADINGS WITH SCOPE NOTES (UNIT RECORD FORMAT; 9/8/2011
HN - 2012(1987) BX - HLA B38 Antigen MH - HLA-B39 Antigen UI - D059946 MN - D12.776.395.550.489.500.390 MN - D12.776.543.550. ... HN - 2012; for HLA-D ALPHA use HLA-DR ANTIGENS 1987-2011 BX - HLA-DR alpha BX - HLA-DR alpha-Chain MH - HLA-DR beta-Chains UI ... HN - 2012; for HLA-D BETA use HLA-DR ANTIGENS 1987-2011 BX - HLA-DR beta MH - HLA-DR Serological Subtypes UI - D059810 MN - ... HLA) surface antigens encoded by alleles on locus B of the HLA complex. The HLA-G antigens are considered non-classical class I ...
Psoriatic Arthritis - StatPearls - NCBI Bookshelf
HLA-B38 and HLA-B39 genes are associated with polyarthritis.[5][3] HLA-B*44:02/03 is protective and associated with milder ... Gladman DD, Anhorn KA, Schachter RK, Mervart H. HLA antigens in psoriatic arthritis. J Rheumatol. 1986 Jun;13(3):586-92. [ ... HLA-B*27:05, HLA-B*38:01, HLA-B*39:01, HLA-B*44:02HLA-B*57:01, and HLA-C*06:02.[6] HLA-B*08:01 is also associated with ... Psoriasis has a stronger association than psoriatic arthritis with HLA-B*57:01 and HLA-C*06:02 (referred to as the psoriasis ...
DeCS
Antigènes HLA-B Entry term(s):. Antigen, HLA-B. Antigens, HLA B. Antigens, HLA-B. HLA B Antigen. HLA B Antigens. HLA-B. HLA-B ... Antigen, HLA-B Antigens, HLA B Antigens, HLA-B HLA B Antigen HLA B Antigens HLA-B HLA-B Antigen ... HLA-B39 Antigen [D12.776.395.550.489.500.390] HLA-B39 Antigen * HLA-B40 Antigen [D12.776.395.550.489.500.400] ... HLA-B Antigens - Preferred Concept UI. M0023414. Scope note. Class I human histocompatibility (HLA) surface antigens encoded by ...
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D12.776.543.550.439.500.370 HLA-B38 Antigen D12.776.543.550.421.500.380 D12.776.543.550.439.500.380 HLA-B39 Antigen D12.776. ... HLA-DR1 Antigen D12.776.543.550.423.400.440.400.10 D12.776.543.550.440.400.440.400.10 HLA-DR2 Antigen D12.776.543.550.423.400. ... HLA-DR3 Antigen D12.776.543.550.423.400.440.400.30 D12.776.543.550.440.400.440.400.30 HLA-DR4 Antigen D12.776.543.550.423.400. ... HLA-DR5 Antigen D12.776.543.550.423.400.440.400.50 D12.776.543.550.440.400.440.400.50 HLA-DR6 Antigen D12.776.543.550.423.400. ...
NDF-RT Code NDF-RT Name
HLA-B27 Antigen N0000171101 HLA-B35 Antigen N0000183467 HLA-B37 Antigen N0000183474 HLA-B38 Antigen N0000183486 HLA-B39 Antigen ... HLA-A Antigens N0000171097 HLA-A1 Antigen N0000183461 HLA-A11 Antigen N0000171096 HLA-A2 Antigen N0000183462 HLA-A24 Antigen ... HLA-A3 Antigen N0000171098 HLA-B Antigens N0000183463 HLA-B13 Antigen N0000183464 HLA-B14 Antigen N0000183465 HLA-B15 Antigen ... HLA-B40 Antigen N0000183469 HLA-B44 Antigen N0000183470 HLA-B51 Antigen N0000183471 HLA-B52 Antigen N0000171099 HLA-B7 Antigen ...
Celiac Disease: Diagnosis and Management | AAFP
The presence of human leukocyte antigen alleles DQ2, DQ8, or both is essential for the development of celiac disease, and can ... The human leukocyte antigen DQ2 and DQ8 alleles are present in 25% to 30% of the general population without celiac disease, but ... Stratifying risk for celiac disease in a large at-risk United States population by using HLA alleles. Clin Gastroenterol ... 2011;77:b39.. *. Bianchi ML, Bardella MT. Bone in celiac disease. Osteoporos Int. 2008;19(12):1705-1716. ...
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D12.776.543.550.439.500.370 HLA-B38 Antigen D12.776.543.550.421.500.380 D12.776.543.550.439.500.380 HLA-B39 Antigen D12.776. ... HLA-DR1 Antigen D12.776.543.550.423.400.440.400.10 D12.776.543.550.440.400.440.400.10 HLA-DR2 Antigen D12.776.543.550.423.400. ... HLA-DR3 Antigen D12.776.543.550.423.400.440.400.30 D12.776.543.550.440.400.440.400.30 HLA-DR4 Antigen D12.776.543.550.423.400. ... HLA-DR5 Antigen D12.776.543.550.423.400.440.400.50 D12.776.543.550.440.400.440.400.50 HLA-DR6 Antigen D12.776.543.550.423.400. ...
Polyarteritis Nodosa Treatment & Management: Approach Considerations, Idiopathic (Non-HBV-Related) PAN, HBV-Related PAN
Cutaneous polyarteritis nodosa associated with HLA-B39-positive undifferentiated spondyloarthritis in a Japanese patient. Mod ... Plasma exchanges are stopped once seroconversion from hepatitis B e antigen to hepatitis B e antibody occurs or after clinical ... However, they are also associated with persistent HBV infection and failure to seroconvert from hepatitis B surface antigen to ... hepatitis B surface antibody and from hepatitis B e antigen to hepatitis B e antibody. Thus, antiviral medications are ...
Polyarteritis Nodosa: Practice Essentials, Pathophysiology, Etiology
24] Cutaneous PAN occurring with HLA-B39 spondyloarthritis, [25] common variable immunodeficiency, [26] and psoriatic arthritis ... Presence of hepatitis B surface antigen or antibody in serum * Arteriogram demonstrating aneurysms or occlusions of the ... Cutaneous polyarteritis nodosa associated with HLA-B39-positive undifferentiated spondyloarthritis in a Japanese patient. Mod ...
A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and...
7 HLA-B (B7, B8, B27, B39, B44, B58, B62) and two HLA-C (C1, C2) supertypes22,23. A total of 97 out of 102 (95.1%) HLA-I ... S3h). Most contributing genes to the MPC1 such as IL10RA, CD48, SLA, suggest that MPC1 describes the antigen presenting cell ( ... S4). Notably, the HLA allele frequency coverage was ,0.6 for both HLA-A and -C genes and ranged from 0.4 to 0.80 for HLA-B in ... In contrast, only 2 out of 6 HLA-A alleles and none of the HLA-B and-C alleles were detected from RNA-Seq of neuroblastoma PDXs ...
The Vasculitis Syndromes | Clinical Gate
Other associations with PsA include HLA-B13, -B37, -B38, -B39, -C12, and -DR4. A recent genome-wide scan found association of ... AS shows a striking correlation with the histocompatibility antigen HLA-B27 and occurs worldwide roughly in proportion to the ... HLA associations have been weak and inconsistent. HLA-B27 is found in up to 70% of patients with IBD and AS, but in ≤15% of ... The HLA-Cw*0602 gene is directly associated with psoriasis, particularly familial juvenile-onset (type I) psoriasis. HLA-B27 is ...
UI - 97479605
HLA-B7 Antigen) RN - 0 (HLA Antigens) DP - 1997 May TA - Rev Invest Clin IS - 0034-8376 JC - SCH PG - 183-187 IP - 3 VI - 49 AB ... B39 PG - 291-294 IP - 3 VI - 5 AB - The objective of this study was to determine the incidence of aortic transaction in ... HLA Antigens/GENETICS/*ANALYSIS MH - HLA-B7 Antigen/ANALYSIS MH - Male MH - Mexico/EPIDEMIOLOGY MH - Pregnancy MH - Pregnancy ... frequency of the HLA-B7 antigen in males belonging to the abortion group. CONCLUSION: These results suggest that HLA-B antigens ...