*  Immunoglobulin D Deficiency: Background, Pathophysiology, Epidemiology
9, 10] IgD deficiency is associated with the specific human leukocyte antigens HLA-B18, F1C30, and DR3 in a Spanish Basque ... The [HLA-B18, F1C30, DR3] conserved extended haplotype carries a susceptibility gene for IgD deficiency. J Clin Immunol. 2000 ... 11] and HLA-B8, SC01, DR3 in white subjects in an American study. [12] A 2008 report noted that depletion of circulating IgD+ ... Prospective analysis suggests susceptibility genes for deficiencies of IgA and several other immunoglobulins on the [HLA-B8, ...
  https://emedicine.medscape.com/article/136803-overview
*  HLA-B18 - Wikipedia
2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301-69. doi:10.1111/j.1399-0039.2005.00379. ... HLA-B18 (B18) is an HLA-B serotype. The serotype identifies the more common HLA-B*18 gene products. (For terminology help see: ... HLA-serotype tutorial) B*1801, the most common allele is at highest frequencies in Northern Italy and the Balkans, a peak ... Tissue Antigens. 61 (5): 403-7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in ,title= (help). ...
  https://en.wikipedia.org/wiki/HLA-B18
*  WiDr ATCC ® CCL-218™ Homo sapiens colon colorectal adenocar
HLA A24, A32, B15, B18. The cells are positive for keratin by immunoperoxidase staining. The cells expressed p53 antigen (the ... carcinoembryonic antigen (CEA) 118 ng/10 exp6 cells/10 days; Colon Specific Antigen (CSAp); transforming growth factor beta; ... carcinoembryonic antigen (CEA) 118 ng/10 exp6 cells/10 days; Colon Specific Antigen (CSAp); transforming growth factor beta; ... The cells expressed p53 antigen (the p53 produced has a G -> A mutation resulting in Arg -> His at position 273). ...
  https://www.atcc.org/products/all/CCL-218.aspx?slp=1
*  A30-Cw5-B18-DR3-DQ2 (HLA Haplotype) - Wikipedia
March 2000). "HLA genes in Arabic-speaking Moroccans: close relatedness to Berbers and Iberians". Tissue Antigens. 55 (3): 239- ... A30-Cw5-B18 and a variant A30-CBL-B18 comprise A30::B18, there is also the B18-DR3 component and the HLA DR3-DQ2.5. Other ... However B18 found in the Middle East is linked to B18-DR11 (DR11 is very common in the Eastern Mediterranean). The level of B18 ... Müller CR, Ehninger G, Goldmann SF (January 2003). "Gene and haplotype frequencies for the loci hLA-A, hLA-B, and hLA-DR based ...
  https://en.wikipedia.org/wiki/A30-Cw5-B18-DR3-DQ2_(HLA_Haplotype)
*  HLA-B - MHC class I antigen - Homo sapiens (Human) - HLA-B gene & protein
Cluster: HLA class I histocompatibility antigen, B-18 alpha chain. 71. Full view ... tr,K4JES8,K4JES8_HUMAN MHC class I antigen (Fragment) OS=Homo sapiens GN=HLA-B PE=3 SV=1 ... Name:HLA-BImported. ,p>Information which has been imported from another database using automatic procedures.,/p> ,p>,a href="/ ... MHC class I antigenImported. ,p>Information which has been imported from another database using automatic procedures.,/p> ,p>,a ...
  http://www.uniprot.org/uniprot/K4JES8
*  Expression of Classic and Nonclassic HLA Class I Antigens in Uveal Melanoma | IOVS | ARVO Journals
HLA-A2, A28, and A29) and three the HLA-B locus (HLA-B18, B35, B55). In two tumor specimens (2 and 8) a haplotype (HLA-A2, B44 ... HLA-A. HLA-A. HLA-B. HLA-B. HLA-C. HLA-C. HLA-A2. ... HLA-A. HLA-A. HLA-B. HLA-B. HLA-C. HLA-C. HLA-A2. ... with known HLA-A, -B, and -C phenotypes. 14 The HLA-C typing of the cell lines covered HLA-C allotypes from HLA-C*01 to HLA-C* ... Therefore, we looked in addition for the expression of these HLA antigens in our tumor specimens. HLA-C antigens were not ...
  http://iovs.arvojournals.org/article.aspx?articleid=2163235
*  HLA A1-B8-DR3-DQ2 - Wikipedia
"Correlation between acetylcholine receptor antibody titer and HLA-B8 and HLA-DRw3 antigens in myasthenia gravis". Trans Am ... There are two major DR3 haplotypes in Europe, A1::DQ2 and A30-B18-DR3-DQ2. Linkage with disease could more firmly be attributed ... Hammarström L, Smith E, Möller E, Franksson C, Matell G, Von Reis G (August 1975). "Myasthenia gravis: studies on HL-A antigens ... Hirsch TJ, Enlow RW, Bias WB, Arnett FC (October 1981). "HLA-D related (DR) antigens in various kinds of myositis". Hum. ...
  https://en.wikipedia.org/wiki/HLA_A1-B8-DR3-DQ2
*  HLA-A*02 - Wikipedia
HLA-A*02 (A*02) is a human leukocyte antigen serotype within the HLA-A serotype group. The serotype is determined by the ... A2-B16 A2-B44 A2-B45 A2-B18 A2-B27 A2-B35 A2-B37 A2-B39 (Node in North American Amerinds) A2-B40 A2-B60 A2-B61 A2-B46 A2-Cw5- ... Before this revision, HLA-A*02 was also referred to as HLA-A2, HLA-A02, and HLA-A*2. HLA-A*02 is one particular class I major ... Tissue Antigens. 11 (2): 96-112. doi:10.1111/j.1399-0039.1978.tb01233.x. PMID 77067. "HLA Nomenclature @ hla.alleles.org". ...
  https://en.wikipedia.org/wiki/HLA-A*02
*  Epitopes - Before the Transplant | Coursera
... we see that all epitopes on the HLA-B18. are also present on one or more of the HLA antigens of the patient. ... However, the patient carries more than one HLA antigen.. If we now have a look at two other HLA antigens carried by the patient ... If we now look at three other HLA antigens,. it is clear that some of these epitopes are shared between different HLA antigens. ... In this lecture, we have learnt that an HLA antigen. consist of a string of epitopes which can be shared between HLA antigens. ...
  https://pt.coursera.org/lecture/clinical-kidney-transplantation/epitopes-g6HBw
*  Method for identifying and validating dominant T helper cell epitopes using an HLA-DM-assisted class II binding assay - The...
Rational design of immunotherapeutics relies on clear knowledge of the immunodominant epitopes of antigens. Current methods for ... a viral antigen, a bacterial antigen, a fungal antigen, a protozoal antigen, a plasmodial antigen, a helminthic antigen, and a ... such as an HLA-DR allele, such as HLA-DR1, HLA-DR2, HLA-DR3, HLA-DR4, HLA-DR5, HLA-DR6, HLA-DR7, HLA-DR8, HLA-DR9, or HLA-DR15 ... The DR molecule may comprise HLA-DRB1, HLA-DRB2, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-DRB6, HLA-DRB7, HLA-DRB8, HLA-DRB9, or HLA- ...
  http://www.freepatentsonline.com/8916340.html
*  HLA class I histocompatibility antigen, B-53 alpha chain
HLA-B13:02, HLA-B38:02, HLA-B44:03, and HLA-B56:01 alleles were significantly increased in autistic subjects. HLA-B18:02 and ... Involved in the presentation of foreign antigens to the immune system. HLA-B belongs to the HLA class I heavy chain paralogues ... The HLA-B*35 antigen contributes to endoplasmic reticulum stress and inflammation in limited cutaneous systemic sclerosis ... HLA-B alleles are associated with dermatitis herpetiformis in Chinese population.. 26841353. KIR-3DL2 binding to HLA-B27 ...
  https://pharos.nih.gov/idg/targets/P30491
*  HLA DR3-DQ2 - Wikipedia
Sirén M, Sareneva H, Lokki M, Koskimies S (1996). "Unique HLA antigen frequencies in the Finnish population". Tissue Antigens. ... The second, propagating A30-B18-DR3-DQ2, is from Africa into Sardinia, Iberia, France and Italy. Anti-node in Western Europe. ... HLA-DR3-DQ2 is found in HLA A1-B8-DR3-DQ2 haplotype in Northern Europeans (including the British Ilse, Ireland, Iceland). HLA ... Klemola T, Savilahti E, Koskimies S, Pelkonen P (1988). "HLA antigens in IgA deficient paediatric patients". Tissue Antigens. ...
  https://en.wikipedia.org/wiki/HLA_DR3-DQ2
*  The Influence of MHC and Immunoglobulins A and E on Host Resistance to Gastrointestinal Nematodes in Sheep
... the HLA-DR3-B18 haplotype is more common than the HLA-DR3-B8 haplotype, suggesting that the IgA deficiency susceptibility gene ... inhibits antigen processing and modulates antigen-specific immune response," Infection and Immunity, vol. 69, no. 12, pp. 7380- ... Antigens are transported from the intestinal lumen to the subepithelial dome, where the antigen-presenting cells interact with ... T. I. A. Roach, K. J. Else, D. Wakelin, D. J. McLaren, and R. K. Grencis, "Trichuris muris: antigen recognition and transfer of ...
  https://www.hindawi.com/journals/jpr/2011/101848/
*  Viruses | Free Full-Text | How much of Virus-Specific CD8 T Cell Reactivity is Detected with a Peptide Pool when Compared to...
The presence of such T cells with very high functional avidity for the viral antigens can explain why the effect of peptide ... can compete for HLA binding sites. What impact such competition has on functional T cell stimulation, however, is not clear. ... Peptides, when restricted by the same HLA allele, and presented from within the same peptide pool, ... elicited a stronger recall response than the HLA-A2-restricted HCMV peptide CEF-7, though this donor was HLA-B18-negative, but ...
  http://www.mdpi.com/1999-4915/4/11/2636/htm
*  Human Gene HLA-C (uc011gww.1) Description and Page Index
U31971 - Human MHC class I antigen HLA-B precursor (HLA-B) mRNA, complete cds.. U35431 - Human MHC class I antigen HLA-B (HLA-B ... HLA-B gene, HLA-B44Null allele).. AM711637 - Homo sapiens partial mRNA for HLA-B protein.. D25275 - Homo sapiens HLA-B18 mRNA, ... U36492 - Human MHC class I antigen (HLA-B) allele HLA-B-8201 mRNA, complete cds.. U38800 - Human HLA class I antigen (HLA-B), B ... X61706 - Human RNA for HLA-Bw50 antigen.. X61707 - Human RNA for HLA-Bw57.2 antigen.. X61708 - Human RNA for HLA-Bw78 antigen. ...
  http://rohsdb.cmb.usc.edu/GBshape/cgi-bin/hgGene?hgg_gene=uc011gww.1&hgg_prot=Q30194&hgg_chrom=chr6_mann_hap4&hgg_start=2585738&hgg_end=2671188&hgg_type=knownGene&db=hg19&hgsid=1289098_rEYyzmWZ9Xw4hhMOGbGzlYRwArae
*  Unrelated Hematopoietic Stem Cell Donor Matching Probability and Search Algorithm
... of unrelated donor peripheral blood HSC transplants from NMDP reported that only HLA-C antigen and HLA-B allele or antigen ... In our experience, among 55 patients with 0 donor in BMDW some serotypes occurred more frequently, such as A25, A33, A68, B18, ... HLA) allele compatibility in patients receiving a marrow transplant from serologically HLA-A, HLA-B, and HLA-DR matched ... A. Woolfrey, J. P. Klein, M. Haagenson et al., "HLA-C antigen mismatch is associated with worse outcome in unrelated donor ...
  https://www.hindawi.com/journals/bmr/2012/695018/
*  JCI - Autoreactive T cells in type 1 diabetes
Selected HLA-I variants such as HLA-A2, HLA-A24, HLA-B39, HLA-B57, and HLA-B18 contribute to T1D risk (3, 6). HLA-A2 is also ... Using HLA multimers, investigators demonstrated the antigen specificity of autoreactive CD8+ T cells in insulitis lesions of ... such as HLA-DQ8/DQ2, who can express HLA-DQ trans-dimers (HLA-DQ8trans, DQA1*05:01/DQB1*03:02 or HLA-DQ2trans, DQA1*03:01/DQB1* ... Strong predisposition for T1D derives from selected HLA class II (HLA-II) haplotypes, especially HLA-DRB1*04 (DR4), DQA1*03:01- ...
  https://jinxiuwang.net.insight.mobile.jci.org/articles/view/94549
*  INTRODUCTOR Y BIOTECHNOLOGY (ABG 504) THEORETICAL MODULE BY
HLA) HLA constitutes a group of cell surface antigens as M HC of humans. Because HLA genes are located at adjacent loci on the ... alleles i HLA-B alleles j Δ ij t A1 B8 0.065 16.0 A3 B7 0.039 10.3 A2 Bw40 0.013 4.4 A2 Bw15 0.01 3.4 A1 Bw17 0.014 5.4 A2 B18 ... 237 C Antigen i − − A1 c = 91 d = 1265 D Total A B N Because HLA is codominant and HLA expression is only tested locus by locus ... M easuring the strength of associations between HLA antigens and diseases.' Tissue Antigens 18(5): 356-363, PM ID 7344182. 12 ...
  http://spotidoc.com/doc/13866/introductor-y-biotechnology--abg-504--theoretical-module--by
*  MHC Haplotype Project
HLA-A HLA-B HLA-C HLA-DRB1 HLA-DQB1 HLA-DPB1 Links:. Vega UCSC. GRC ... A26-B18-DR3 26:01:01 18:01:01 05:01:01:01 03:01:01:02 02:01:01 02:02 Vega UCSC. GL000255.1 ... The table below lists the eight cell lines used in the project along with their HLA haplotypes and alleles. Links are given to ... It provides the genomic sequences and gene annotation of 8 different HLA-homozygous typing haplotypes (listed below), their ...
  http://www.ucl.ac.uk/cancer/research/department-cancer-biology/medical-genomics-group/past-projects/mhc-haplotype-project
*  Association between human leucocyte antigen subtypes and risk of end stage renal disease in Taiwanese: a retrospective study |...
HLA-A and -B antigens did not show any contribution of progression to ESRD. However, we note that the significance of all these ... The polymorphisms of HLA class I and II antigens in ESRD patients and a healthy control group were retrospectively analyzed. ... Human leukocyte antigens (HLA) have been found to be associated with the pathogenesis of autoimmune diseases, allergies and ... In order to standardize the HLA designation of prior low-resolution typings with the more advanced DNA based typings, all HLA-A ...
  https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-015-0165-7
*  Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis
HLA-DR7, and HLA-DRB3*0301 (Figure 2, middle). We also confirm previously reported association signals with HLA-B18 and HLA-B21 ... Tissue Antigens 63: 237-247.HF HarboBA LieS. SawcerEG CeliusKZ Dai2004Genes in the HLA class I region may contribute to the HLA ... and identify novel associations to HLA-DR6 (encompassing HLA-DRB1*1401), HLA-DR8 (including HLA-DRB1*0802 and *0803), and HLA- ... Other novel associations in UC are demonstrated for HLA-DR5 (and its subspecificities HLA-DR11 and -DR12), HLA-A19 and HLA-A24. ...
  http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1000024
*  Hitchhiker's Guide to the Galaxy on Linkage disequilibrium
Example: Human leukocyte antigen (HLA) alleles HLA constitutes a group of cell surface antigens as MHC of humans. Because HLA ... Table 2. Linkage disequilibrium among HLA alleles in Pan-europeans[10] HLA-A alleles i. HLA-B alleles j. Δ. i. j. {\ ... B18. 0.006. 2.2. A2. Bw35. -0.009. -2.3. A29. B12. 0.013. 6.0. A10. Bw16. 0.013. 5.9. ... Antigen i. +. {\displaystyle +}. A. 1. +. {\displaystyle A1^{+}}. a. =. 376. {\displaystyle a=376}. b. =. 237. {\displaystyle b ...
  http://hitchhikersgui.de/Linkage_disequilibrium