HIV-1 transmission among HIV-1 discordant couples before and after the introduction of antiretroviral therapy - MSMGF Men Who...
HIV & AIDSMSMPrevention Interventions (ARV-Based)Region - ResearchResearch Leave a Reply Cancel reply. You must be logged in to ... Global Forum MSM HIV @MSMGF Saturday, January 20th, 2018 at 9:05am. Here is what happened during the 3 days of the IP summit ; ... Global Forum MSM HIV @MSMGF Saturday, January 20th, 2018 at 9:02am. You can watch here what happened at the Global Summit on ... Global Forum MSM HIV @MSMGF Saturday, January 20th, 2018 at 9:04am. Congratulations to the Malaysia Ministry of Health #GSIPA2M ...http://msmgf.org/hiv-1-transmission-among-hiv-1-discordant-couples-before-and-after-the-introduction-of-antiretroviral-therapy/
A Study to Assess the Safety and Effectiveness of Darunavir for Treating Human Immunodeficiency Virus-Type I (HIV-1) Infection...
HIV Protease Inhibitors. Protease Inhibitors. Enzyme Inhibitors. Molecular Mechanisms of Pharmacological Action. Anti-HIV ... HIV Infections. Immune System Diseases. Lentivirus Infections. Retroviridae Infections. RNA Virus Infections. Virus Diseases. ... A Study to Assess the Safety and Effectiveness of Darunavir for Treating Human Immunodeficiency Virus-Type I (HIV-1) Infection ... HIV-1) infection among adult Filipino patients. The study will enroll 10 percentage of patient who would use the product, as a ...https://clinicaltrials.gov/show/NCT01726348?order=460
Evidence of Self-Sustaining Drug Resistant HIV-1 Lineages Among Untreated Patients in the United Kingdom | UK HIV Drug...
Drug Resistance, Viral/*genetics, Female, Great Britain/epidemiology, HIV Infections/*epidemiology/*virology, HIV-1-transmitted ... Evidence of Self-Sustaining Drug Resistant HIV-1 Lineages Among Untreated Patients in the United Kingdom. Title. Evidence of ... METHODS: We extracted all subtype B HIV-1 pol gene sequences from treatment-naive patients within the United Kingdom HIV Drug ... HIV-1/*classification/*genetics, Humans, Male, Models, Statistical, Phylogeny, subtype B, treatment-naive patients. ...http://www.hivrdb.org.uk/publication/evidence-self-sustaining-drug-resistant-hiv-1
Microbiology Society Journals | Lack of viral selection in human immunodeficiency virus type 1 mother-to-child transmission...
HIV-1) as described for women with an established infection is, in most cases, associated with the transmission of few maternal ... which could play a role in MTCT of HIV-1. ... Luzuriaga, K. ( 2007 ). Mother-to-child transmission of HIV: a ... HIV seroconversion during pregnancy and risk for mother-to-infant transmission. Bangkok Collaborative Perinatal HIV ... Pizzo, P. A. & Butler, K. M. ( 1991 ). In the vertical transmission of HIV, timing may be everything. N Engl J Med 325, 652-654 ...http://jgv.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.83697-0
Patente US7507417 - Immunogenic compositions comprising human immunodeficiency virus type 2 (HIV ... - Google Patentes
The gp300, which is a dimeric form of gp140, the precursor of HIV-2 envelope glycoprotein, is probably formed by a pH dependent ... Such a doublet is also observed in cells infected with simian immunodeficiency virus (SIV), a virus closely related to HIV-2. ... The gp300 is useful for detecting antibodies to HIV-2 antigens in human body fluids and for raising antibodies to gp300. ... The gp125 and gp36 are the external and transmembrane components, respectively, of the envelope glycoproteins of HIV-2 mature ...http://www.google.es/patents/US7507417
Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to...
We conclude that studies of HIV-1 neutralization that rely on strains adapted to growth in transformed T-cell lines yield the ... The more relevant primary HIV-1 isolates are relatively resistant to neutralization, although these isolates can be potently ... HIV-1) was tested for neutralization of nine primary HIV-1 isolates, one molecularly cloned primary strain (JR-CSF), and two ... However, one HuMAb, IgG1b12, was able to neutralize most of the primary isolates at concentrations of , or = 1 microgram/ml. ...https://www.neuroscience.ox.ac.uk/publications/30698
Mutations that abrogate human immunodeficiency virus type 1 reverse transcriptase dimerization affect maturation of the reverse...
HIV core protein p24. HIV protease. HIV-1 reverse transcriptase. indinavir. mutation. protein precursors. virion ... We have previously characterized mutations at codon 401 in the HIV-1 RT tryptophan repeat motif that abrogate RT dimerization ... The introduction of the RT dimerization-inhibiting mutations W401L and W401A into HIV-1 resulted in the formation of ... The treatment of transfected cells with indinavir suggested that the HIV-1 protease contributed to the degradation of virion- ...http://dro.deakin.edu.au/view/DU:30047542
Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell...
These data are consistent with data from studies of other HLA-class I alleles associated with HIV control that have shown that ... HIV-1), we analyzed the role of HLA-B*13, an allele associated with low viremia, in a cohort of 578 C clade-infected ... better understand relationships between CD8+ T-cell specificity and the immune control of human immunodeficiency virus type 1 ( ... These data are consistent with data from studies of other HLA-class I alleles associated with HIV control that have shown that ...https://www.paediatrics.ox.ac.uk/publications/191128
Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational...
HIV-1)-specific CD8(+) T-cell responses restricted by two closely related HLA class I alleles, B*5701 and B*5703, that differ ... by two amino acids but are both associated with a dominant response to the same HIV-1 Gag epitope KF11 (KAFSPEVIPMF). When this ... Alleles, Amino Acid Substitution, CD8-Positive T-Lymphocytes, Epitopes, T-Lymphocyte, Gene Products, gag, HIV Infections, HIV-1 ... HIV-1)-specific CD8(+) T-cell responses restricted by two closely related HLA class I alleles, B*5701 and B*5703, that differ ...https://www.rdm.ox.ac.uk/publications/191130
Quantification of the epitope diversity of HIV-1-specific binding antibodies by peptide microarrays for global HIV-1 vaccine...
60 APPLIED LIFE SCIENCES; HIV; peptide microarray; diversity; antibody; vaccine. OSTI Identifier:. 1201749. ... Our data suggest that the global HIV-1 peptide microarray may be a useful tool for both preclinical and clinical HIV-1 research ... Using this microarray, we quantified the magnitude, breadth, and depth of IgG binding to linear HIV-1 sequences in HIV-1- ... Here we describe the development of a global HIV-1 peptide microarray that contains 6564 peptides from across the HIV-1 ...https://www.osti.gov/pages/biblio/1201749-quantification-epitope-diversity-hiv-specific-binding-antibodies-peptide-microarrays-global-hiv-vaccine-development
Cervical and vaginal shedding of human immunodeficiency virus type 1-infected cells throughout the menstrual cycle
In multivariate analyses, plasma HIV-1 RNA was significantly associated with shedding of HIV-1-infected cells; each 1-unit ... HIV-1) were evaluated daily through the course of one menstrual cycle for HIV-1 DNA (21-31 visits per woman). HIV-1-infected ... Cervical and vaginal shedding of human immunodeficiency virus type 1-infected cells throughout the menstrual cycle. ... Cervical and vaginal secretions from 17 women infected with human immunodeficiency virus type 1 ( ...http://erepository.uonbi.ac.ke:8080/xmlui/handle/11295/28396
Generation and evaluation of simian-human immunodeficiency virus subtype AE challenge stocks (VIR2P.1166) | The Journal of...
However, the overwhelming majority of HIV/AIDS-related deaths occur in the developing world and are from other HIV-1 subtype ... The sequences were identified from acutely infected HIV-1 individuals from Southeast Asia. The challenge stocks efficiently ... HIV-1) vaccine development efforts have focused on HIV-1 subtype B strains from the western world. ... challenge stocks from HIV-1 subtype AE env sequences. ... and other interventions aimed at controlling the spread of HIV- ...http://www.jimmunol.org/content/194/1_Supplement/75.5
Human immunodeficiency virus type 1 virological synapse formation in T cells requires lipid raft integrity. - Oxford...
We investigated the distribution of GM1-rich lipid rafts in HIV-1-infected (effector) T cells and observed Env colocalization ... HIV-1) can spread directly between T cells by forming a supramolecular structure termed a virological synapse (VS). HIV-1 ... We investigated the distribution of GM1-rich lipid rafts in HIV-1-infected (effector) T cells and observed Env colocalization ... Antigens, Viral, CD4-Positive T-Lymphocytes, G(M1) Ganglioside, HIV-1, Humans, In Vitro Techniques, Jurkat Cells, Membrane ...https://www.neuroscience.ox.ac.uk/publications/25173
HLA-associated viral mutations are common in human immunodeficiency virus type 1 elite controllers | BC Centre for Excellence...
HIV-1) maintain viremia below the limit of detection without antiretroviral treatment. Virus-specific cytotoxic CD8(+) T ... HIV Drug Safety. Safety Alerts. Report Adverse Drug Reactions * Healthcare Resources. Resources of particular interest to ... Copyright BC Centre for Excellence in HIV/AIDS, St. Paul's Hospital. 608-1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6. ... HIV-1) maintain viremia below the limit of detection without antiretroviral treatment. Virus-specific cytotoxic CD8(+) T ...http://www.cfenet.ubc.ca/publications/hla-associated-viral-mutations-are-common-human-immunodeficiency-virus-type-1-elite
"Mycobacterium tuberculosis reactivates latent HIV-1 in T cells in vitr" by Erica Larson, Camille Novis et al.
HIV-1 reactivation occurs when transcription factors, such as nuclear factor-κB (NF-κB), nuclear factor of activated T cells ( ... Using a JLAT model of HIV-1 latency, we found this interaction to be mediated through Toll-like receptor-2 (TLR-2). Thus, we ... Some PRRs are expressed on central memory CD4+ T cells (TCM), which in HIV-1 patients constitute the main reservoir of latent ... However, the ability of Mtb to reactivate latent HIV-1 has not been extensively studied. Here we show that phosphatidylinositol ...https://hsrc.himmelfarb.gwu.edu/smhs_microbio_facpubs/305/
Effect of Complement on HIV-2 Plasma Antiviral Activity Is Intratype Specific and Potent
Previous studies have shown that the neutralizing antibody response is more potent and broader in HIV-2 than HIV-1 infection. ... Previous studies have shown that the neutralizing antibody response is more potent and broader in HIV-2 than HIV-1 infection. ... Previous studies have shown that the neutralizing antibody response is more potent and broader in HIV-2 than HIV-1 infection. ... HIV-1 and HIV-2 host interactions (research group). publishing date. 2013. type. Contribution to journal publication status. ...https://lup.lub.lu.se/search/publication/ff4f8a23-6ca4-4f67-9971-6842888c6b56
Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte...
Here we describe a perinatally HIV-infected child who maintained a plasma viral load of ,400 copies/ml for almost a decade ... The child subsequently experienced a reemergence of HIV-1 viremia accompanied by a marked increase in the number of CTL ... HIV-1) proteins has been anecdotally associated with progression to AIDS, but it has been difficult to determine whether viral ... Amino Acid Sequence, Child, Disease Progression, Epitopes, T-Lymphocyte, HIV Infections, HIV Long-Term Survivors, HIV-1, HLA- ...https://www.paediatrics.ox.ac.uk/publications/191173
... Varyc varyc.mmcri at OFFICE.MMC.ORG Tue Oct 18 12:02:28 EST 1994 *Previous message: Free BioTechniques Past Paper ... Does anyone know of an HIV-1 DNA test panel that can be used to establish sensitivity/specificity of a set of pcr reagents. I'd ...http://www.bio.net/bionet/mm/methods/1994-October/019816.html
HIV 1 - HIV Prevention - MedHelp
HIV/AIDS Treatment Options: An Overview What are your HIV treatment options, and how do you choose the right one? Our panel of ... Can You Get HIV By Doing This? Can HIV be transmitted through this sexual activity? Dr. Jose Gonzalez-Garcia answers this ... Black Women Still at High Risk for HIV/AIDS Despite the drop in new infections, black women are still at a high risk for HIV, ... I am concerned that I may have been exposed to HIV 2 but only tested for HIV 1. Does anyone know if HIV1 and HIV2 are routinely ...https://www.medhelp.org/posts/HIV-Prevention/HIV-1/show/18635
The Future of HIV-1 Therapeutics | SpringerLink
HIV-1 inhibitor resistance is discussed in detail, and critical assessmen ... This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. ... Fragment-based drug design HIV Gag protein HIV capsid HIV integrase protein HIV matrix HIV nucleocapsid protein HIV protease ... HIV reverse transcriptase protein HIV stem-loop HIV transcription HIV-1 antiretroviral treatment HIV-1 drug resistance HIV-1 ...https://link.springer.com/book/10.1007/978-3-319-18518-7
Measuring HIV-1 persistence in vivo
Total HIV DNA: a global marker of HIV persistence Among the different markers of HIV persistence in infected cells, total HIV ... Inducible HIV RNA transcription assays to measure HIV persistence: pros and cons of a compromise With the increasing number of ... Cell-associated (CA) HIV RNA has received much attention in recent years as a surrogate measure of the efficiency of HIV ... HIV evolution and diversity in ART-treated patients Characterizing HIV genetic diversity and evolution during antiretroviral ...https://www.biomedcentral.com/collections/hivpersistence
HIV-1 Nomenclature Proposal | Science
HIV-1 Nomenclature Proposal. By D. L. Robertson, J. P. Anderson, J. A. Bradac, J. K. Carr, B. Foley, R. K. Funkhouser, F. Gao, ... HIV-1 Nomenclature Proposal. By D. L. Robertson, J. P. Anderson, J. A. Bradac, J. K. Carr, B. Foley, R. K. Funkhouser, F. Gao, ... HIV/AIDS and Retrovirology Branch, Center for Disease Control and Prevention, Atlanta GA, USA; ... HIV/AIDS and Retrovirology Branch, Center for Disease Control and Prevention, Atlanta GA, USA; ...http://science.sciencemag.org/content/288/5463/55.4
New insights into HIV-1 vaccine design
Scientists have created a computational model that could change the way that researchers look at possibilities for an HIV-1 ... New insights into HIV-1 vaccine design. New insights into HIV-1 vaccine design. Scientists have created a computational model ... "An effective HIV-1 vaccine has proven elusive, partly due to the difficulty of causing an immune response that can neutralize ... "An effective HIV-1 vaccine has proven elusive, partly due to the difficulty of causing an immune response that can neutralize ...https://www.lanl.gov/discover/news-release-archive/2015/September/09.17-hiv1-vaccine-design.php
Procleix HIV-1/HCV Assay
... ,Donor Screening: The Procleix System has added a significant layer of a safety to the nation's blood ... VERSANT HIV RNA 3.0 Assay (bDNA). 7. Wampole PreVue B. Burgdorferi Antibody Detection Assay. 8. VerifyNow Aspirin Assay. 9. ... The Procleix HIV-1/HCV Assay can simultaneously detect the presence of HIV-1 and HCV in blood donor samples *The combination ... The combination HIV-1/HCV test system was developed and manufactured by Gen-Probe and is marketed worldwide as the Procleix ...http://www.bio-medicine.org/medicine-products/Procleix-HIV-1-HCV-Assay-9829-1/
Transmission of HIV-1 Drug Resistance | SpringerLink
Infection with an HIV strain harboring drug resistance-related mutations is referred to as transmitted drug resistance (TDR) or ... Katzenstein DA, Holodniy M (1995) HIV viral load quantification, HIV resistance, and antiretroviral therapy. AIDS Clin Rev 96: ... Gianella S, Richman DD (2010) Minority variants of drug-resistant HIV. J Infect Dis 202(5):657-666PubMedCentralCrossRefPubMed ... Boden D et al (1999) HIV-1 drug resistance in newly infected individuals. JAMA 282(12):1135-1141CrossRefPubMedGoogle Scholar ...https://link.springer.com/referenceworkentry/10.1007/978-1-4939-0667-3_23-1