... and Brazil as a foundation for integrating secondary HIV prevention into HIV treatment. From 2010-2012, 80 qualitative ... Participants had a high degree of HIV transmission risk awareness and practiced some protective sexual behaviors such as ... Emphasizing sexual health, intimacy and protective practices as components of nonjudgmental sex-positive secondary HIV ... Part of the interview focused on the impact of HIV on sexual practices and relationships. Interviews were recorded, transcribed ...

Of the total cases, HIV status was documented for 3,144 (84.2%), among whom, 712 (22.6%) were HIV positive. The TB/HIV co- ... The overall case fatality rate was 13% (n = 486), with considerable variation among HIV-positives and HIV-negative TB patients ... TB/HIV co-infection, sputum smear-negative pulmonary TB and district of anti-TB treatment predicted TB mortality. Conclusion TB ... In this context, we explored the trends of TB case detection, mortality and HIV co-infection, and examined the predictors of TB ...

... and Africa have a markedly greater risk of being HIV-infected than does the general population. ...

While mobile clinics have been used effectively for HIV testing and linkage, evidence guiding their use in providing HIV care ... To guide the development of a mobile HIV clinic (MHC) model as a strategy to re-engage and retain PLWH who are out of care, we ... From June 2019-July 2020, we conducted 41 in-depth interviews with HIV clinic providers, administrators, staff, legal ... Participants provided suggestions regarding appropriate exterior design, location, timing, and co-delivery of non-HIV services ...

At week 4, 59.3% of HIV-positive men and 70.4% of age-matched HIV-negative men were healed. At week 6, these percentages rose ... There was no difference in the hazard of healing between 108 HIV-positive and 108 age-matched HIV-negative men (HR 0.91 95% CI ... A total of 215 HIV-negative and 108 HIV-positive men aged 18-35 years (median 26, IQR 23-30) were enrolled. 97.1% of scheduled ... Early post-operative infection was associated with delayed healing in both HIV-positive and HIV-negative men (HR 0.48 95% CI ...

HIV-1 subtype C is responsible for majority of global HIV-1 infections. In the present study, we examined the diversity in ... A total of 1814 full length HIV-1 subtype C gp120 sequence from 37 countries were retrieved from Los Alamos National Laboratory ... HIV database (www.hiv.lanl.gov). The amino acid sequences were assessed for their phylogenetic association, variable loop ... global intra-subtype C gp120 sequences are likely to influence the disparate region-specific sensitivity of circulating HIV-1 ...

... and evaluate the risks and benefits of addressing HIV/AIDS as a national security issue. ... Feldbaum and colleagues look at evidence on the links between HIV and national security, ...

An oral point-of-care HIV test, an Internet and paper-based self-test HIV applications, and mobile phones were synergized to ... Non-invasive, oral self-tests offer a potential for a confidential, unsupervised HIV self-testing option, but global data are ... With 50% of adults having ever tested for HIV in their lifetime, private, alternative testing options are urgently needed. ... Of 270 health care workers (18 years and above, of unknown HIV status approached), 251 consented for participation. Findings ...

... multiple antigens to the immune system to elicit an optimal vaccine as observed preclinically with mosaic/polyvalent HIV ...

In Kenya, approximately 1.6 million people are living with HIV and have a 20-times higher risk of dying of tuberculosis. ... With the aim of integrating HIV and tuberculosis care in rural Kenya, a team of researchers, clinicians, and technologists used ...

... and better adherence to drugs are needed to eliminate pediatric HIV in Zimbabwe. ... prevention of mother to child transmission of HIV) guidelines plus better access to PMTCT programs, better retention of women ... or HIV-infected), as well as one of three maternal disease categories (HIV-uninfected, HIV-infected and "ART eligible," or HIV- ... Infants enter this model at birth and are assigned one of three HIV categories (HIV-unexposed, HIV-exposed but uninfected, ...

Increased T cell trafficking as adjunct therapy for HIV-1 Helen R. Fryer, Steven M. Wolinsky, Angela R. McLean ...

Our results identify a dense network of interactions between HLA alleles and HIV codons, as well as among HIV codons, ... Recently, several studies have analyzed large groups of HIV-infected individuals and looked for correlations between HIV ... Here, we point out a limitation of previous approaches: correlations among HLA alleles and HIV codons lead to statistical ... reflecting both a complexity and a promising consistency in the way that HIV adapts to the human immune response. ...

We identified six pairs of HLA class I alleles that have a co-operative additive effect in mediating HIV disease control and ... to quantify the breadth of CD8+ T cell responses made by pairs of HLA alleles across the HIV proteome, and used this to ... appear to function co-operatively to result in greater immune control of HIV than mediated by either single allele alone. We ... 2000 subjects infected with C-clade HIV first to discern the individual effect of each allele on disease control, and second to ...

HIV prevalence was high in this sample of FSW (70%), but knowledge that AI increases HIV acquisition risk low, with only 10% ... among Swazi FSW and to identify the correlates of AI practice in order to better inform HIV prevention interventions among this ... Introduction As HIV is very effectively acquired during condomless receptive anal intercourse (AI) with serodiscordant and ... HIV epidemiology Is the Subject Area "HIV epidemiology" applicable to this article? Yes. No. ...

The Ab genes of these clones were highly mutated, but they did not neutralize common HIV strains. We sought to further define ... To enhance for isolation of quaternary epitope-targeting Abs (QtAbs), we previously used HIV virus-like particles (VLPs) to ... which may be targeted by the naturally occurring Ab response to HIV infection. ... target epitopes that are formed or enhanced during mature HIV envelope formation (i.e. quaternary epitopes). Generally, it is ...

Some, women, however had limited understanding and believed that a vasectomy would protect a man from HIV as well as preventing ... Many women in this study were aware that vasectomy did not offer protection against HIV and other infections associated with ... The number of women that asked if a vasectomy would provide protection against HIV suggested a need for knowledge that ...

Multivariate analyses showed that men living with HIV, engaged in condomless anal intercourse with men, and used gay apps were ... HIV Is the Subject Area "HIV" applicable to this article? Yes. No. ...

The HIV status of the study participants was not known despite this being an important risk factor for a poor outcome in ... HIV/AIDS Programme, World Health Organization, geneva. *27. Chang AB, Redding GJ, Everard ML (2008) Chronic wet cough: ... Future studies, such as recently undertaken in Kenya [27] need to clarify if CPT provides post-discharge benefit for HIV- ... However, it is unlikely to be an important confounder in this population given that Bangladesh has a very low HIV prevalence ...

An accessible sialyllactose moiety on viral membrane gangliosides is shown to be essential for HIV-1 uptake into mature ... and PS-containing LUVHIV-tRed. Alternatively, cells were incubated with 75 ng of VLPHIV-Gag-eGFP Gag and 100 µM of LUVHIV-tRed ... To produce HIVNL4-3 in PBMCs, cells were stimulated with 3 µg/ml PHA and 10 IU/ml of IL-2 for 72 h prior to infection with HIV ... Accordingly, carriage of HIV-1 by mDCs could facilitate the loss of antigen-specific CD4+ T cells [32],[33], favoring HIV-1 ...

Results Of 990 HIV-positive patients with depression, 493 (50%) patients used mental health services; 182 (18%) used primary ... More effective mental health policies and better access to mental health services are required to address HIV-positive patient ... Methods We conducted a prospective cohort study linking data from the Ontario HIV Treatment Network Cohort Study with ... Conclusions Our results showed gaps in delivering publicly funded mental health services to depressed HIV-positive patients and ...

Methods In Hlabisa sub-district, home-based HIV services, including rapid HIV testing and counselling, and support for linkage ... Health care workers however expressed concerns about the ability of home-based services to answer the HIV care needs of all ... health care workers regarding home-based strategies as opportunities to improve the cascade of care of people living with HIV ... to and retention in clinic-based HIV care, were implemented by health care workers within the ANRS 12249 Treatment-as- ...

Among repeat testers, HIV incidence was 8.2/100 PY, 95% CI, 3.7/100PY to 18.3/100PY. Conclusion HIV risks and rates varied by ... Interest in participation was high, 86.3% for PrEP, 69.7% for HIV vaccine trials, but 29.9% for circumcision. HIV was ... sexual behavior and interest in future HIV prevention trials among gay and bisexual MSM and TG presenting for HIV testing (VCT ... HIV prevalence among MSM overall was 12.9% (71/551); 16.5% among gay men, 9.3% among TG, and 6.9% among BS. Consistent use of ...

... a probable indication of high transmission especially in the presence of high HIV co-infection. Conclusions and recommendations ... In both 2011 and 2012, ninety (90%) of cases were new and had a high human immunodeficiency virus (HIV)/TB co-infection rate of ... HIV epidemiology Is the Subject Area "HIV epidemiology" applicable to this article? Yes. No. ... HIV Is the Subject Area "HIV" applicable to this article? Yes. No. ...

Using in vitro HIV-1 replication assays with a CD4+ T cell line and peripheral blood mononuclear cells, we confirmed antiviral ... Moreover, ixoratannin A-2 was less effective at inhibiting replication of HIV-1 lacking Vpu, supporting this protein as a ... In contrast, boldine was less effective against a protease inhibitor-resistant HIV-1 strain. Both ixoratannin A-2 and boldine ... We identified eight molecules with structural similarity to reported interactors of Vpu, an HIV-1 accessory protein with ...

Hepatitis B, hepatitis C and HIV transfusion-transmitted infections in the 21st century. Vos Sang. 2011;100: 92-98. pmid: ...

Thirty-three studies were able to be meta-analyzed across five HIV-related outcomes. Results from meta-analysis demonstrate ... Students who received school-based sex education interventions had significantly greater HIV knowledge (Hedges g = 0.63, 95% ... Intervention effects were synthesized through random effects meta-analysis for five outcomes: HIV knowledge, self-efficacy, ... and middle-income countries to determine the efficacy of these interventions in changing HIV-related knowledge and risk ...

PCP was more prevalent in patients newly-diagnosed with HIV (11.4%) than in patients with known HIV (1.1%; p = 0.007). ... We explored the prevalence of both PCP in HIV-infected adults admitted with pneumonia to a tertiary-care hospital in Uganda and ... PCP is an important cause of pneumonia in patients newly-diagnosed with HIV in Uganda, is associated with high mortality, and ... but its burden is incompletely characterized in those areas of sub-Saharan Africa where HIV is prevalent. ...

Background HIV infection is a major contributor to maternal mortality in resource-limited settings. The Drug Resource ... and Malnutrition Programme has been promoting HAART use during pregnancy and postpartum for Prevention-of-mother-to-child-HIV ... HIV Is the Subject Area "HIV" applicable to this article? Yes. No. ... European HIV in Obstetrics Group (2004) Higher rates of post-partum complications in HIV-infected than in uninfected women ...

The clarifying role of time series data in the population genetics of HIV * View Page ...