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*  High Glucose Inhibits the Aspirin-Induced Activation of the Nitric Oxide/cGMP/cGMP-Dependent Protein Kinase Pathway and Does...
Effect of L-ASA on platelet cGMP in the presence of different glucose concentrations without and with the guanylate cyclase ... or the guanylate cyclase inhibitor MB (50 μmol/L). Some experiments have been carried out with the iso-osmolar control mannitol ... this effect is attributable to the NO-induced activation of guanylate cyclase, as it was completely prevented by both l-NMMA ... The thrombin inhibitors hirudin and Refludan(®) activate the soluble guanylyl cyclase and the cGMP pathway in washed human ...
  http://diabetes.diabetesjournals.org/content/61/11/2913.full
*  NPR2 - Wikipedia
Natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B), also known as NPR2, is an atrial ... NPR2 natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)". Fox AA, Collard CD, Shernan SK ... Schulz S (2005). "C-type natriuretic peptide and guanylyl cyclase B receptor". Peptides. 26 (6): 1024-34. doi:10.1016/j. ... van den Akker F (2001). "Structural insights into the ligand binding domains of membrane bound guanylyl cyclases and ...
  https://en.wikipedia.org/wiki/NPR2
*  Guanylate cyclase - Wikipedia
Guanylate cyclase (EC 4.6.1.2, also known as guanyl cyclase, guanylyl cyclase, or GC) is a lyase enzyme. Guanylate cyclase is ... soluble guanylate cyclase) forms of guanylate cyclases. Membrane bound guanylate cyclases include an external ligand-binding ... and Function of Mammalian Membrane Guanylate Cyclase Receptors, With a Focus on Guanylate Cyclase-A". Circulation Research. 93 ... Guanylyl cyclase activator (protein). References[edit]. *^ Sakurai K.; Chen J.; Kefalov V. (2011). "Role of guanylate cylcase ...
  https://en.wikipedia.org/wiki/Guanylate_cyclase
*  DailyMed - Search Results for Guanylate Cyclase Activators
SEARCH RESULTS for: Guanylate Cyclase Activators [Drug Class] (4 results) * Share : JavaScript needed for Sharing tools. ...
  https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Guanylate%20Cyclase%20Activators&searchdb=class
*  Anti-Guanylate Cyclase antibody (ab53084) Protocols | Abcam
Abcam provides specific protocols for Anti-Guanylate Cyclase antibody (ab53084) : Western blot protocols, Immunohistochemistry ...
  http://www.abcam.com/guanylate-cyclase-antibody-ab53084-protocols.html
*  Membrane Events and Guanylate Cyclase Activation in Mitogen-Stimulated Lymphocytes | SpringerLink
Coffey, R.G., Hadden, E.M., and Hadden, J.W., 1981, Phytohemagglutinin stimulation of guanylate cyclase in human lymphocytes, J ... Hadden J.W., Hadden E.M., Coffey R.G. (1985) Membrane Events and Guanylate Cyclase Activation in Mitogen-Stimulated Lymphocytes ... Lymphocyte Proliferation Cyclic Nucleotide Guanylate Cyclase Lymphocyte Activation Phorbol Myristate Acetate These keywords ... Oxidative-reductive modulation of guinea pig splenic cell guanylate cyclase activity, J. Biol. Chem. 253:3143.PubMedGoogle ...
  https://link.springer.com/chapter/10.1007/978-1-4684-4946-4_46
*  Bee venom enhances guanylate cyclase activity | Science
Bee venom and phospholipase A2 extracted from bee venom enhanced guanylate cyclase (E.C. 4.6.1.2) activity two- to threefold in ... 1 microgram per milliliter and phospholipase A2 at 1 microunit per milliliter caused a maximal enhancement of guanylate cyclase ...
  http://science.sciencemag.org/content/213/4505/359
*  Guanylate Cyclase: Inhibition by Light in Retinal Photoreceptors | Science
Guanylate Cyclase: Inhibition by Light in Retinal Photoreceptors Message Subject. (Your Name) has forwarded a page to you from ... Guanylate Cyclase: Inhibition by Light in Retinal Photoreceptors. By Richard E. Bensinger, R. Theodore Fletcher, Gerald J. ... Guanylate Cyclase: Inhibition by Light in Retinal Photoreceptors. By Richard E. Bensinger, R. Theodore Fletcher, Gerald J. ... Guanylate cyclase activity of retinal rod outer segments was measured by an assay procedure that minimizes the technical ...
  http://science.sciencemag.org/content/183/4120/86
*  gucy2c - Guanylate cyclase - Xenopus laevis (African clawed frog) - gucy2c gene & protein
PS00452. GUANYLATE_CYCLASE_1. 1 hit. PS50125. GUANYLATE_CYCLASE_2. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. ... PS00452. GUANYLATE_CYCLASE_1. 1 hit. PS50125. GUANYLATE_CYCLASE_2. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. ... Guanylate cyclaseUniRule annotation. ,p>Information which has been generated by the UniProtKB automatic annotation system, ... Guanylate cyclaseSequence analysis. ,p>Information which has been generated by the UniProtKB automatic annotation system, ...
  http://www.uniprot.org/uniprot/P79991
*  Effect of Guanylate Cyclase-C Activity on Energy and Glucose Homeostasis | Diabetes
Effect of Guanylate Cyclase-C Activity on Energy and Glucose Homeostasis. Denovan P. Begg, Kris A. Steinbrecher, Joram D. Mul, ... Effect of Guanylate Cyclase-C Activity on Energy and Glucose Homeostasis. Denovan P. Begg, Kris A. Steinbrecher, Joram D. Mul, ... Guanylate cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitis. PLoS ONE 2013;8:e79180pmid: ... Effect of Guanylate Cyclase-C Activity on Energy and Glucose Homeostasis Message Subject (Your Name) has forwarded a page to ...
  http://diabetes.diabetesjournals.org/content/63/11/3798.long
*  Mutational Inactivation of the Catalytic Domain of Guanylate Cyclase-A Receptor | Hypertension
Guanylate Cyclase Assay. Guanylate cyclase was assayed at 37°C in the presence of 50 mmol/L Tris, pH 7.6, 2 mmol/L ... Identification of a Mutant of the Catalytic Domain of Guanylate Cyclase (GC-c-2-23) That Lacks Guanylate Cyclase Activity. To ... Fig 2⇓ (top panel) shows guanylate cyclase activity in column fractions of this chromatographic procedure. Guanylate cyclase ... guanylate cyclase activity eluted as a 200-kD protein. Fractions 31 through 34 that contained high guanylate cyclase activity ...
  http://hyper.ahajournals.org/content/25/4/694
*  Catalytic domain of guanylate cyclase - Stock Image C035/5787 - Science Photo Library
Computer model showing the structure of the catalytic domain of eukaryotic guanylate cyclase (green, blue). PO4 residues shown ... Caption: Catalytic domain of eukaryotic guanylate cyclase. Computer model showing the structure of the catalytic domain of ... guanylate cyclase, illustration, molecular model, molecular structure, molecule, nitric oxide, nobody, protein, space-fill, ... Keywords: art, artwork, biochemical, biochemistry, biological, biology, black background, catalytic, compound, cyclase, ...
  http://www.sciencephoto.com/media/847185/view
*  Pharmacological Activation of Soluble Guanylate Cyclase Protects the Heart Against Ischemic Injury | Circulation
The novel soluble guanylate cyclase activator cinaciguat has been reported to elevate intracellular [cGMP] and activate the ... Pharmacological Activation of Soluble Guanylate Cyclase Protects the Heart Against Ischemic Injury. Sevil Korkmaz, Tamás ... It has been proposed that the nitric oxide (NO)/soluble guanylate cyclase (sGC)/cGMP/cGMP-dependent protein kinase G pathway ... The nitric oxide/soluble guanylate cyclase/cGMP/cGMP-dependent protein kinase G signaling cascade has been shown to be an ...
  http://circ.ahajournals.org/content/120/8/677
*  US Patent # 9,611,278. Soluble guanylate cyclase activators - Patents.com
Soluble guanylate cyclase activators Abstract. A compound of Formula I or a pharmaceutically acceptable salt thereof, are ... Active soluble guanylate cyclases are each composed of an .alpha. and a .beta. subunit. Several subunit subtypes have been ... It has now been found that the compounds of the present invention effect a strong activation of guanylate cyclase and are ... The soluble guanylate cyclases ("sGC"), which are cytosolic heterodimeric heme proteins, in contrast, are essentially regulated ...
  http://patents.com/us-9611278.html
*  Soluble Guanylate Cyclase (sGC or EC 4.6.1.2) - Pipeline Review, H1 2018
... Summary:. Soluble Guanylate Cyclase (sGC or EC 4.6. ... Soluble Guanylate Cyclase (sGC or EC 4.6.1.2) - Dormant Products. Soluble Guanylate Cyclase (sGC or EC 4.6.1.2) - Discontinued ... Guanylate Cyclase (Guanyl Cyclase or Guanylyl Cyclase or GC) Activators -Pipeline Insight, 2018 * Drug Pipelines ... Soluble Guanylate Cyclase (sGC or EC 4.6.1.2) - Overview. Soluble Guanylate Cyclase (sGC or EC 4.6.1.2) - Therapeutics ...
  https://www.researchandmarkets.com/reports/4473287/soluble-guanylate-cyclase-sgc-or-ec-4-6-1-2
*  gcy-5 - Receptor-type guanylate cyclase gcy-5 precursor - Caenorhabditis elegans - gcy-5 gene & protein
Unlike other guanylate cyclases expressed in ASE neurons, may not play a role in chemotaxis responses to salt ions mediated by ... Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). ... PS00452 GUANYLATE_CYCLASE_1, 1 hit. PS50125 GUANYLATE_CYCLASE_2, 1 hit. PS50011 PROTEIN_KINASE_DOM, 1 hit. ... PS00452 GUANYLATE_CYCLASE_1, 1 hit. PS50125 GUANYLATE_CYCLASE_2, 1 hit. PS50011 PROTEIN_KINASE_DOM, 1 hit. ...
  https://www.uniprot.org/uniprot/Q23682
*  Guanylate cyclase activator - Wikipedia
A guanylate cyclase activator (or "GUCA") is one of group of proteins which upregulates guanylate cyclase. It is also known as ... Guanylate Cyclase-Activating Proteins at the US National Library of Medicine Medical Subject Headings (MeSH). ... 1998). "A mutation in guanylate cyclase activator 1A (GUCA1A) in an autosomal dominant cone dystrophy pedigree mapping to a new ... guanylate cyclase-activating protein, with the abbreviation "GCAP". Mutations can be associated with vision defects. There are ...
  https://en.wikipedia.org/wiki/Guanylate_cyclase_activator
*  Guanylate cyclase 2C - Wikipedia
Guanylate cyclase 2C, also known as guanylyl cyclase C (GC-C), intestinal guanylate cyclase, guanylate cyclase-C receptor, or ... Kulaksiz H, Cetin Y (2001). "Uroguanylin and guanylate cyclase C in the human pancreas: expression and mutuality of ligand/ ... Ghanekar Y, Chandrashaker A, Tatu U, Visweswariah SS (2004). "Glycosylation of the receptor guanylate cyclase C: role in ligand ... 2002). "Guanylin, uroguanylin, and heat-stable euterotoxin activate guanylate cyclase C and/or a pertussis toxin-sensitive G ...
  https://en.wikipedia.org/wiki/Guanylate_cyclase_2C
*  SPO2978 - Adenylate/guanylate cyclase - Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) - SPO2978 gene & protein
Guanylate cyclaseInterPro annotation. ,p>Information which has been generated by the UniProtKB automatic annotation system, ... Adenylate/guanylate cyclaseImported. ,p>Information which has been imported from another database using automatic procedures.,/ ... tr,Q5LP72,Q5LP72_RUEPO Adenylate/guanylate cyclase OS=Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) OX=246200 GN= ... IPR001054. A/G_cyclase. IPR032710. NTF2-like_dom_sf. IPR029787. Nucleotide_cyclase. IPR037401. SnoaL-like. ...
  http://www.uniprot.org/uniprot/Q5LP72
*  Guanylate cyclase-coupled receptor - Wikipedia
Guanylate cyclase-coupled receptor or Membrane-bound guanylyl cyclase is a single transmembrane protein. They are enzyme-linked ... Guanylate Cyclase-Coupled Receptors at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ...
  https://en.wikipedia.org/wiki/Guanylate_cyclase-coupled_receptor
*  Guanylate cyclase activator 2B - Wikipedia
Guanylate cyclase activator 2B is a protein that in humans is encoded by the GUCA2B gene. This gene encodes a preproprotein ... Guanylate cyclase activator 2B". Retrieved 2017-07-04. Sindić A, Hirsch JR, Velic A, Piechota H, Schlatter E (2005). "Guanylin ... a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this ... "Haplotype-based case-control study of the association between the guanylate cyclase activator 2B (GUCA2B, Uroguanylin) gene and ...
  https://en.wikipedia.org/wiki/Guanylate_cyclase_activator_2B
*  LB 118 - Adenylate/guanylate cyclase - Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) - LB 118...
Guanylate cyclaseInterPro annotation. ,p>Information which has been generated by the UniProtKB automatic annotation system, ... Adenylate/guanylate cyclaseImported. ,p>Information which has been imported from another database using automatic procedures.,/ ... PS50125. GUANYLATE_CYCLASE_2. 1 hit. PS50005. TPR. 1 hit. PS50293. TPR_REGION. 1 hit. ... PS50125. GUANYLATE_CYCLASE_2. 1 hit. PS50005. TPR. 1 hit. PS50293. TPR_REGION. 1 hit. ...
  http://www.uniprot.org/uniprot/Q8EXU0
*  Soluble Guanylate Cyclase Antibody for ELISA, WB/Western LS-C15634
Soluble Guanylate Cyclase antibody LS-C15634 is an unconjugated mouse monoclonal antibody to human Soluble Guanylate Cyclase. ... Soluble Guanylate Cyclase antibody LS-C15634 is an unconjugated mouse monoclonal antibody to human Soluble Guanylate Cyclase. ... Soluble Guanylate Cyclase antibody LS-C15634 is an unconjugated mouse monoclonal antibody to human Soluble Guanylate Cyclase. ... Popular Soluble Guanylate Cyclase Products. Soluble Guanylate Cyclase Antibody (clone GC25) LS‑C52468 ...
  https://www.lsbio.com/antibodies/soluble-guanylate-cyclase-antibody-elisa-wb-western-ls-c15634/16375
*  cGMP: Generators, Effectors and Therapeutic Implications by Alexander Y. Kots, Emil Martin, Iraida G. Sharina, Ferid - A Lus do...
... addressing all contemporary advances in figuring out guanylate cyclase rules, NO/sGC interactions, cGMP effector mechanisms and ... Resonance Raman and infrared spectroscopic studies of high-output forms of human soluble guanylyl cyclase. J Am Chem Soc 127: ... 4625-4631 Martin E, Berka V, Bogatenkova E, Murad F, Tsai A L (2006) Ligand selectivity of soluble guanylyl cyclase - effect of ... and genes that encode for either putative histidine kinases or diguanylate cyclases are found in the same predicted operon. ...
  http://alusdomundo.com/kindle/c-gmp-generators-effectors-and-therapeutic-implications