*  Rasgrf2 - Ras-specific guanine nucleotide-releasing factor 2 - Mus musculus (Mouse) - Rasgrf2 gene & protein
Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for ... Ras-specific guanine nucleotide-releasing factor 2Add BLAST. 1189. Amino acid modifications. Feature key. Position(s). ... sp,P70392,RGRF2_MOUSE Ras-specific guanine nucleotide-releasing factor 2 OS=Mus musculus OX=10090 GN=Rasgrf2 PE=1 SV=2 ... "Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation ...
  http://www.uniprot.org/uniprot/P70392
*  Rasgrf2 MGI Mouse Gene Detail - MGI:109137 - RAS protein-specific guanine nucleotide-releasing factor 2
IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal. IPR030744 Ras-specific guanine nucleotide-releasing factor 2 ... IPR019804 Ras guanine-nucleotide exchange factor, conserved site. IPR023578 Ras guanine nucleotide exchange factor domain ... RASGRF2, Ras protein specific guanine nucleotide releasing factor 2. Orthology source: HomoloGene, HGNC ... IPR036964 Ras guanine-nucleotide exchange factor catalytic domain superfamily. ...
  http://www.informatics.jax.org/marker/MGI:109137
*  ENSDARG00000002816 - Zebrafish Mutation Project - Wellcome Sanger Institute
Ras-specific guanine nucleotide-releasing factor 2 [Source:UniProtKB/Swiss-Prot;Acc:A2CEA7]. Human Orthologue:. RASGRF2. Human ... Ras protein-specific guanine nucleotide-releasing factor 2 [Source:HGNC Symbol;Acc:9876]. Mouse Orthologue:. Rasgrf2. Mouse ... RAS protein-specific guanine nucleotide-releasing factor 2 Gene [Source:MGI Symbol;Acc:MGI:109137]. ...
  https://www.sanger.ac.uk/sanger/Zebrafish_Zmpgene/ENSDARG00000002816
*  RASGRF2 - Wikipedia
Ras-specific guanine nucleotide-releasing factor 2 is a protein that in humans is encoded by the RASGRF2 gene. RAS (MIM 190020 ... RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2". "Binge Drinking Gene: RASGRF-2 Helps Explain Teenage ... Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound form into the active ... 2004). "Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors". Mol. Cell. ...
  https://en.wikipedia.org/wiki/RASGRF2
*  BDgene Database
Ras protein-specific guanine nucleotide-releasing factor 2. 5q13. 1(0/0/1) TAS ... guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2. 3p21.31. 1(0/1/0) TAS ... guanine nucleotide binding protein (G protein), beta polypeptide 3. 12p13. 2(1/1/0) TAS ... guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type. 18p11.22-p11.21. 2(0/2/0 ...
  http://bdgene.psych.ac.cn/goDetail.do?name=GO:0007268
*  BrainStars: One-state Genes
RAS protein-specific guanine nucleotide-releasing factor 2. 6. 1417215_at 0.931346. 1243. 5.72827. 0.340566. 1. Rab27b. RAB27b ... TF=Transcription Factor; Ch=Channel; GPCR=GPCR; CA=Cell Adhesion; EM=Extracellular Matrix; SP=Structural Protein; Ng= ... First ‹Prev 1 2 3 4 ... Next› Last» Probe set ID. Variability score. Variability rank. Mean. Standard Deviation. Present ...
  http://brainstars.org/onestate/?sortkey=pcalls
*  Peptides Derived from Neuronal Cell Cycle like Kinase 5 Activator p35, in Neurodegeneration; Pathology and Therapy | OMICS...
2004) p35/cyclin-dependent kinase 5 phosphorylation of ras guanine nucleotide releasing factor 2 (RasGRF2) mediates Rac- ... 2006) Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression. Genes Dev 20: 836-847. ... Upregulation of BDNF in the hippocampus may have been a contributing factor. ... We have shown that duration of glucose toxicity is a key factor in regulation; short term (2 h) resulted in a modest increase ...
  https://www.omicsonline.org/open-access/peptides-derived-from-neuronal-cell-cycle-like-kinase-5-activator-p35-inneurodegeneration-pathology-and-therapy-2161-0460-1000338.php?aid=92430
*  rian.ie - Results
Prompted by a genome-wide association meta-analysis implicating the Ras-specific guanine nucleotide-releasing factor 2 (RASGRF2 ... silver eels captured at Killaloe are released below the hydropower dam as part of a 'trap and transport' conservation strategy ... Females were dominated by 2 year olds, while males were dominated by 3 year olds. Lx was estimated as 38cm and a growth rate ... The chemical nuclease of [Cu(Phen)2]2+ (where Phen = 1,10-phenanthroline), is a well studied reagent which randomly cleaves ...
  http://rian.ie/en/search/results/q/k+all%3Abiology%3BL%3A150%2C25%3B
*  RAS Pathway v2.0 - National Cancer Institute
Ras protein-specific guanine nucleotide-releasing factor 2. GRF2, RAS-GRF2. RASGRP1. RAS guanyl-releasing protein 1. CALDAG- ... Rap guanine nucleotide exchange factor (GEF) 1. C3G, GRF2. RAPGEF2. Rap guanine nucleotide exchange factor (GEF) 2. CNrasGEF, ... Ras protein-specific guanine nucleotide-releasing factor 1. CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1. ... ral guanine nucleotide dissociation stimulator-like 1. RGL. RGL2. ral guanine nucleotide dissociation stimulator-like 2. HKE1.5 ...
  https://www.cancer.gov/research/key-initiatives/ras/ras-central/blog/2015/ras-pathway-v2
*  Anti-SOS2 antibody (ab85831) | Abcam
Guanine nucleotide exchange factor antibody. *Guanine nucleotide releasing factor antibody. *Son of sevenless (Drosophilia) ... Lane 2 : Whole cell lysate from HeLa cells at 15 µg. Lane 3 : Whole cell lysate from HeLa cells at 50 µg. Lane 4 : Whole cell ... Lane 2: Control IgG.. ab85831 at 1µg/ml for WB.. Whole cell lysate from Hela cells at 1mg for IP, 20% of IP loaded. ...
  http://www.abcam.com/sos2-antibody-ab85831.html
*  Protocols and Video Articles Authored by Pablo Pereira
RasGRP1, a guanine nucleotide-releasing factor for Ras, plays an important role in positive selection of αβT cells by ... The factors that control the normal expression of PLZF in lymphocytes are unknown. In this study, we show that PLZF expression ... The PLZF transcription factor is essential for the innate phenotype of NKT cells. This report shows that PLZF is likewise ... This study defines the factors that control the propensity of the immune system to produce potentially disease-causing T cell ...
  https://www.jove.com/author/Pablo_Pereira
*  Pleckstrin homology domain - Wikipedia
Insulin receptor substrate 1 (IRS-1). Regulators of small G-proteins like guanine nucleotide releasing factor GNRP (Ras-GRF) ( ... guanine nucleotide exchange proteins like vav, dbl, SoS and S. cerevisiae CDC24, GTPase activating proteins like rasGAP and ... 217 (2): 608-615. doi:10.1006/bbrc.1995.2818. PMID 7503742. Wang, D. S.; Shaw, R.; Winkelmann, J. C.; Shaw, G. (1994). "Binding ... doi:10.1016/0968-0004(94)90108-2. PMID 7985225. Pawson, T. (1995). "Protein modules and signalling networks". Nature. 373 (6515 ...
  https://en.wikipedia.org/wiki/Pleckstrin_homology_domain
*  GRB2 (Growth factor receptor-bound protein 2)
Growth factor receptor-bound protein 2), Authors: Gagani Athauda, Donald P Bottaro. Published in: Atlas Genet Cytogenet Oncol ... The two GRB2 SH3 domains bind to the proline-rich regions of the guanine nucleotide releasing factor son of sevenless (SOS-1) ... nerve growth factor (TrkA/TrkB), platelet-derived growth factor, colony-stimulating factor-1, and hepatocyte growth factor (HGF ... In these cells the SH3 domains of GRB2 bind Vav-family proteins, guanine nucleotide exchange factors for Rho-family GTPases. ...
  http://atlasgeneticsoncology.org/Genes/GC_GRB2.html
*  anti-RAC1 Primary Antibodies
anti-Ras Protein-Specific Guanine Nucleotide-Releasing Factor 2 Antikörper * anti-Ras Protein-Specific Guanine Nucleotide- ... and their migration was not reduced by Rac1-guanine exchange factor (GEF (zeige ARHGEF2 Antikörper))-inhibition. PDGFR-alpha ( ... a critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically ... anti-Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) Antikörper ...
  https://www.antikoerper-online.de/regulation-of-actin-filament-polymerization-pathway-56/rac1-antibody-8249/
*  anti-RHOU antibody (Internal Region) | Product No. ABIN350806
anti-Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 Antibodies * anti-Ras Protein-Specific Guanine Nucleotide- ... anti-RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) Antibodies * anti-RAS Guanyl Releasing Protein 2 (Calcium and ... Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP ... anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) Antibodies * anti-Ras Association Domain-Containing Protein 6 ...
  http://www.antibodies-online.com/antibody/350806/anti-Ras+Homolog+Gene+Family,+Member+U+RHOU+Internal+Region+antibody/
*  The Ras guanine nucleotide exchange factor RasGRF1 promotes matrix metalloproteinase-3 production in rheumatoid arthritis...
Recently, expression and post-translational modification of Ras guanine nucleotide releasing factor 1 (RasGRF1) was found to ... a) Immunoblot analysis of Ras guanine nucleotide-releasing factor 1 (RasGRF1) in rheumatoid arthritis (RA) and osteoarthritis ( ... Recently, expression and post-translational modification of Ras guanine nucleotide releasing factor 1 (RasGRF1) was found to ... Immunoblot analysis of Ras guanine nucleotide-releasing factor 1 (RasGRF1) and actin in rheumatoid arthritis (RA) and ...
  https://arthritis-research.biomedcentral.com/articles/10.1186/ar2785
*  Eukaryotic elongation factors - Wikipedia
... serving as the guanine nucleotide exchange factor for α, catalyzing the release of GDP from α. The second elongation factor is ... Eukaryotic elongation factors are very similar to those in prokaryotes. Elongation in eukaryotes is carried out with two ... nobelprize.org Explaining the function of eukaryotic elongation factors. ... elongation factors: eEF-1 and eEF-2. The first is eEF-1, and has two subunits, α and βγ. α acts as counterpart to prokaryotic ...
  https://en.wikipedia.org/wiki/Eukaryotic_elongation_factors
*  HA1 recombinant protein | HA1 (H1N1) (A/Brisbane/59/2007) Recombinant Protein
Ras protein-specific guanine nucleotide-releasing factor 2 (... ELISA Kit. • alpha 1-Acid Glycoprotein (Orm1) Antibody. • CD11b ... Keratinocyte Growth Factor (KGF) ELISA Kit. • Fibroblast Growth Factor 2 (FGF-2) ELISA Kit. • Goat anti Rabbit IgG Secondary ... Eukaryotic Translation Elongation Factor 1 Gamma (EEF1g) ELISA Kit. • Cathelicidin Antimicrobial Peptide (CAMP) ELISA Kit. • ... 2-Methoxy Estradiol (2-ME2) ELISA Kit. • 25(OH) Vitamin D ELISA Kit. • ...
  https://www.mybiosource.com/prods/Recombinant-Protein/HA1-H1N1-A-Brisbane-59-2007/HA1/datasheet.php?products_id=434097
*  RANBP1 - Wikipedia
Steggerda, S M; Paschal B M (July 2000). "The mammalian Mog1 protein is a guanine nucleotide release factor for Ran". J. Biol. ... Steggerda SM, Paschal BM (2000). "The mammalian Mog1 protein is a guanine nucleotide release factor for Ran". J. Biol. Chem. ... RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. RANBP1 has been ... Kehlenbach RH, Dickmanns A, Kehlenbach A, Guan T, Gerace L (July 1999). "A Role for RanBP1 in the Release of CRM1 from the ...
  https://en.wikipedia.org/wiki/RANBP1
*  List of MeSH codes (D12.776.476) - Wikipedia
... eukaryotic initiation factor-2b MeSH D12.776.476.325.300.300 -- guanine nucleotide-releasing factor 2 MeSH D12.776.476.325. ... ral guanine nucleotide exchange factor MeSH D12.776.476.325.300.700 -- ras guanine nucleotide exchange factors MeSH D12.776. ... tnf receptor-associated factor 1 MeSH D12.776.476.024.500.750 -- tnf receptor-associated factor 2 MeSH D12.776.476.024.500.875 ... tnf receptor-associated factor 3 MeSH D12.776.476.024.500.937 -- tnf receptor-associated factor 5 MeSH D12.776.476.024.500.968 ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.476)
*  SOS1 - Wikipedia
"Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling". Nature. 363 ( ... "Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling". Nature. 363 ( ... GTP binding can be catalyzed by guanine nucleotide exchange factors for RAS, and GTP hydrolysis can be accelerated by GTPase- ... a guanine nucleotide exchange factor for Ras that binds to GRB2". Science. 260 (5112): 1338-43. doi:10.1126/science.8493579. ...
  https://en.wikipedia.org/wiki/SOS1
*  Plus it
... growth factor receptor-bound protein; GRF: guanine nucleotide releasing factor; PKC: protein kinase C; IP3: inositol 1, 4, 5 ... endothelial-derived growth factor, insulin like growth factor 1, fibroblast growth factor and IL-1 13, 14, 81, 82. It is known ... transforming growth factor-β, epithelial growth factor, insulin-like growth factor, PDGF) and inflammatory mediators, which ... Hypoxia is able to increase cell proliferation by inhibition (production and/or release) of antimitogenic factors (e.g. NO and ...
  http://erj.ersjournals.com/content/30/2/364
*  Ran (gene) - Wikipedia
Steggerda SM, Paschal BM (2000). "The mammalian Mog1 protein is a guanine nucleotide release factor for Ran". J. Biol. Chem. ... the nucleotide exchange factor for Ran. RCC1 is also known as RanGEF (Ran Guanine nucleotide Exchange Factor). Ran's intrinsic ... By releasing importins, RanGTP activates these factors and therefore promotes the assembly of the mitotic spindle . In ... Renault L, Kuhlmann J, Henkel A, Wittinghofer A (2001). "Structural basis for guanine nucleotide exchange on Ran by the ...
  https://en.wikipedia.org/wiki/Ran_(gene)
*  RCC1 - Wikipedia
Steggerda, S M; Paschal B M (July 2000). "The mammalian Mog1 protein is a guanine nucleotide release factor for Ran". J. Biol. ... Ran guanine nucleotide exchange factor and RanGEF, is the name for a human gene and protein. RCC1 also functions as a guanine ... "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor". J. Biol. Chem. 277 (20): 17385-8. doi:10.1074/ ... "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor". J. Biol. Chem. United States. 277 (20): 17385- ...
  https://en.wikipedia.org/wiki/RCC1
*  SMART: RasGEF domain annotation
The latter proteins are known as guanine-nucleotide exchange (or releasing) factors (GEFs or GRFs) (or also as guanine- ... Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. ... This rate-limiting step in GTP binding is thought to be catalysed by a guanine-nucleotide-releasing factor (GRF). Here we ... GRB2 overexpression led to increased formation of a complex between the guanine nucleotide-releasing factor Sos (the product of ...
  http://smart.embl-heidelberg.de/smart/do_annotation.pl?DOMAIN=RasGEF&BLAST=DUMMY