Anti-PLA2G1B Antibody, - OriGene
phospholipase A2 group IB. Alternative Name. PLA2,PLA2A,PPLA2. Database Link. NP_000919 Entrez Gene 5319 Human. Entrez Gene ... Phospholipase A2 (EC 22.214.171.124) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are ... One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been ...http://www.origene.com/antibody/TA302575.aspx
Purification and biochemical characterization of pancreatic phospholipase A2 from the common stingray Dasyatis pastinaca.
Mammalian sPLA2-IB are well characterized. In contrast, much less is known about aquatic ones. The aquatic world contains a ... Group IB Phospholipases A2 / isolation & purification*, metabolism. Hydrogen-Ion Concentration. Kinetics. Pancreas / enzymology ... ostrich phospholipase A2; PLA2: phospholipase A2; SPLA2: stingray phospholipase A2, sPLA2-IB: secreted pancreatic phospholipase ... Kolko M,Prause JU,Bazan NG,Heegaard S,Human secretory phosp holipase A(2), group IB in normal eyes and in eye diseasesActa ...http://www.biomedsearch.com/nih/Purification-biochemical-characterization-pancreatic-phospholipase/21329523.html
PLA2G1B - PrimePCR Assay and Template | Life Science | Bio-Rad
phospholipase A2, group IB (pancreas) Assay Type: EvaGreen Application: Gene Expression Unique Assay ID: dHsaEG5016521 Info: EG ... phospholipase A2, group IB (pancreas) Assay Type: Probe Application: Gene Expression Unique Assay ID: dHsaCPE5048690 Info: FAM ... phospholipase A2, group IB (pancreas) Assay Type: Probe Application: Gene Expression Unique Assay ID: dHsaCPE5048691 Info: HEX ... phospholipase A2, group IB (pancreas) Assay Type: SYBR® Green Assay Design: Intron-spanning Application: Gene Expression Unique ...http://www.bio-rad.com/en-us/prime-pcr-assays/gene/pla2g1b-human
PLA2G1B - Wikipedia
"Entrez Gene: PLA2G1B phospholipase A2, group IB (pancreas)". Sæle O, Nordgreen A, Olsvik PA, Hamre K (2010). "Characterisation ... Phospholipase A2, group 1B is an enzyme that in humans is encoded by the PLA2G1B gene. Phospholipase A2 (EC 126.96.36.199) catalyzes ... and expression of secretory phospholipase A2 group IB during ontogeny of Atlantic cod ( Gadus morhua)". Br J Nutr. 105 (2): 1- ... "Diversity of group types, regulation, and function of phospholipase A2". J Biol Chem. 269 (18): 13057-60. PMID 8175726. " ...https://en.wikipedia.org/wiki/PLA2G1B
Purification and biochemical characterization of a secreted group IIA chicken intestinal phospholipase A2 | Springer for...
Background Secretory phospholipase A2 group IIA (IIA PLA2) is a protein shown to be highly expressed in the intestine of ... Exogenously added human group X secreted phospholipase A(2) but not the group IB, IIA, and V enzymes efficiently release ... Nevalainen TJ, Haapanen TJ: Distribution of pancreatic (group I) and synovial-type (group II) phospholipases A2 in human ... Role of group IIA phospholipase A2. J Clin Invest. 1998, 102 (3): 633-638. 10.1172/JCI3121PubMedCentralCrossRefPubMedGoogle ...https://rd.springer.com/article/10.1186/1476-511X-10-27
Constitutive and Lysophosphatidic Acid (LPA)-induced LPA Production: Role of Phospholipase D and Phospholipase A2 | Clinical...
Both the group IIA sPLA2 inhibitor manoalide and the group IB sPLA2 inhibitor OOEPC reduced LPA-induced production of LPA by ∼ ... Group IB (pancreatic) secretory PLA2 plays a critical role in both constitutive and LPA-induced LPA formation, whereas group ... Inhibitors of PLD, pancreatic (group IB) sPLA2 and cPLA2/iPLA2, but not a nonpancreatic (group IIA) sPLA2, inhibitor block LPA- ... Inhibitors of PLD, pancreatic (group IB) sPLA2 and cPLA2/iPLA2, but not a nonpancreatic (group IIA) sPLA2 inhibitor block ...http://clincancerres.aacrjournals.org/content/6/6/2482
KEGG PATHWAY: hsa00564
PLA2G12B; phospholipase A2 group XIIB [KO:K01047] [EC:188.8.131.52]. 5319 PLA2G1B; phospholipase A2 group IB [KO:K01047] [EC:184.108.40.206 ... PLA2G16; phospholipase A2 group XVI [KO:K16817] [EC:220.127.116.11 18.104.22.168] ... PNPLA6; patatin like phospholipase domain containing 6 [KO:K14676] [EC:22.214.171.124] ... PNPLA7; patatin like phospholipase domain containing 7 [KO:K14676] [EC:126.96.36.199] ...http://www.genome.jp/dbget-bin/www_bget?pathway+hsa00564
Gentaur Molecular :Biovis \ Octyl-β-D-thioglucopyranoside \ 1782-50G
PLA2G1B PLA2 PLA2A PPLA2] Phospholipase A2 (EC 188.8.131.52) (Group IB phospholipase A2) (Phosphatidylcholine 2-acylhydrolase 1B). [ ... BRCA2 FACD FANCD1] Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein). [ABO] Histo-blood group ABO ... Histo-blood group A transferase) (A transferase) (Histo-blood group B transferase) (B transferase) (NAGAT) [Cleaved into: ... PPARG NR1C3] Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3). [ ...http://www.antibody-antibodies.com/product_det.php?id=1772565&supplier=search&name=Octyl_%CE%B2_D_thioglucopyranoside
Human Metabolome Database: Showing metabocard for LysoPC(22:1(13Z)) (HMDB0010399)
4. Group IIF secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ... Platelet-activating factor acetylhydrolase IB subunit gamma. General function:. Involved in hydrolase activity. Specific ... 9. Group IIE secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ... 8. Group 10 secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ...http://www.hmdb.ca/metabolites/HMDB10399
A2 - Wikipedia
... an Afro-Asiatic family of languages spoken in Nigeria A2, a second language level in the IB Group 2 subjects A2, a level in the ... a protein Apolipoprotein A2, a protein Phospholipase A2, an enzyme Prokaryotic phospholipase A2, an enzyme Hemoglobin A2, a ... A2, A02, A002, A², A.II or A-2 may refer to: A2 Racer, a racing computer game series A2 - Secret of the Slavers Stockade, a ... A2, a variant of blood groups alleles A in the ABO blood group system A-box 2 of insulin gene HLA-A2, a human MHC HLA-A ...https://en.wikipedia.org/wiki/A2
Human Metabolome Database: Showing metabocard for PC(16:0/22:5(7Z,10Z,13Z,16Z,19Z)) (HMDB0007990)
4. Group 10 secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ... Probable phospholipid-transporting ATPase IB. General function:. Involved in ATP binding. Specific function:. ATP + H(2)O + ... Group XIIA secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ... Group IIF secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ...http://www.hmdb.ca/metabolites/HMDB07990
Anthera Announces Preliminary Positive Results From Once-Daily A-002 Phase II Cardiovasc... ( SAN MATEO Calif. Jan. 15 /-...
The primary endpoint was reduction in secretory phospholipase A2 (sPLA2) levels. Secondary endpoints included a number of lipid ... Announces Successful Phase Ib Results for DOV 21,947. 9. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical ... a group of enzymes responsible for the release of arachidonic acid and subsequent production of leukotrienes prostacyclins and ... to a series of clinical and pre-clinical compounds that inhibit the enzymatic activity of members of the phospholipase A2 (PLA2 ...http://www.bio-medicine.org/medicine-technology-1/Anthera-Announces-Preliminary-Positive-Results-From-Once-Daily-A-002-Phase-II-Cardiovascular-Trial-1202-1/
Human Metabolome Database: Showing metabocard for LysoPC(10:0) (HMDB0003752)
Membrane-associated phospholipase. Exhibits a calcium-independent broad substrate specificity including phospholipase A2/ ... Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Gene Name:. PAFAH1B2. Uniprot ... 4. Platelet-activating factor acetylhydrolase IB subunit gamma. General function:. Involved in hydrolase activity. Specific ... 1. Cytosolic phospholipase A2. General function:. Involved in metabolic process. Specific function:. Selectively hydrolyzes ...http://www.hmdb.ca/metabolites/HMDB03752
phospholipase A2, group IIA (platelets, synovial fluid) /// phospholipase A2, group IIA (platelets, synovial fluid). 0.0139. ... alcohol dehydrogenase IB (class I), beta polypeptide. 0.0177. 0.9993. Hs.370704. ---. CDNA FLJ36685 fis, clone UTERU2008018. ... phospholipase A1 member A /// phospholipase A1 member A. 0.0151. 0.9995. Hs.2316. SOX9. SRY (sex determining region Y)-box 9 ( ... phospholipase C, delta 4 /// phospholipase C, delta 4. -0.0088. 0.0002. Hs.64313. FLJ36748. hypothetical protein FLJ36748. - ...http://cmgm.stanford.edu/~kimlab/aging_muscle/supp_table_2.htm
Molecular Interactions Leading to Lipoprotein Retention and the Initiation of Atherosclerosis | Arteriosclerosis, Thrombosis,...
LDL treatment with phospholipase A2 increased its binding.52 A neighboring region to site B, site A (residues 3148 to 3158), ... The observed interactions were interpreted as an ionic binding of positively charged amino groups on apoB to negatively charged ... B-Ib at residues 84 to 94) located in the amino terminus of apoB is masked by the carboxyl terminus of apoB100 in apoB100- ... The modifications include lipolysis by sphingomyelinases or phospholipases,89 or complexation to proteoglycans.90 In addition, ...http://atvb.ahajournals.org/content/24/12/2211
Toxins | Free Full-Text | Molecular Characterization of Lys49 and Asp49 Phospholipases A2 from Snake Venom and Their Antiviral...
Group IA), and pancreatic svPLA2s (Group IB), while group II is found abundantly in the venom of viperidae snakes [5,7]. The ... Scott, D.L. Phospholipase A2 Structure and Catalytic Properties. In Venom Phospholipase A2 Enzymes, Structure; Function and ... On the other hand, group II differs from group I in having an extended C-terminal tail [6,8]. ... The thiol groups of purified proteins (1.5 mg each) were S-reduced and alkylated with vinyl pyridine as described . The ...http://www.mdpi.com/2072-6651/5/10/1780/htm
IJMS | Free Full-Text | Lipid Based Therapy for Ulcerative Colitis-Modulation of Intestinal Mucus Membrane Phospholipids as a...
Fabia, R; Ar'Rajab, A; Willen, R; Andersson, R; Bengmark, S. Effect of putative phospholipase A2 inhibitors on acetic acid- ... Einerhand, AW; Renes, IB; Makkink, MK; van der Sluis, M; Buller, HA; Dekker, J. Role of mucins in inflammatory bowel disease: ... Crohn's Disease cA2 Study Group. N. Engl. J. Med 1997, 337, 1029-1035. [Google Scholar] ... Yedgar, S; Cohen, Y; Shoseyov, D. Control of phospholipase A2 activities for the treatment of inflammatory conditions. Biochim ...http://www.mdpi.com/1422-0067/11/10/4149/htm
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) Primary Antibodies
PAFAH Ib phospholipase A2 (zeige YWHAZ Antikörper) subunits have distinct roles in maintaining Golgi structure and function. ... a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating ... isoform Ib, alpha subunit 45kDa , lissencephaly 1 protein , platelet-activating factor acetylhydrolase, isoform Ib, alpha ... anti-Pleckstrin Homology Domain Containing Family A2 Antikörper * anti-Pleckstrin Homology Domain Containing Family A3 ...https://www.antikoerper-online.de/m-phase-pathway-68/pafah1b1-antibody-17809/
Interleukin 6 Inhibition and Coronary Artery Disease in a High‐Risk Population: A Prospective Community‐Based Clinical Study |...
Secretory phospholipase A2‐IIA and cardiovascular disease: a Mendelian randomization study. J Am Coll Cardiol. 62:1966-1976. ... Of the 60 patients enrolled in the study, 18 comprised the tocilizumab group, 18 the anti-TNF‐α group, and 24 the sDMARD group ... McInnes IB, Thompson L, Giles JT, Bathon JM, Salmon JE, Beaulieu AD, Codding CE, Carlson TH, Delles C, Lee JS, Sattar N. Effect ... α group, there was improvement from 4.78% (2.13-7.42) to 6.75% (4.10-9.39) (P=0.09), and in the sDMARD group, FMD increased ...http://jaha.ahajournals.org/content/6/3/e005038
Tissue expression of PAFAH1B3 - Summary - The Human Protein Atlas
GO:0004623 [phospholipase A2 activity]. GO:0005515 [protein binding]. GO:0005737 [cytoplasm]. GO:0005829 [cytosol]. GO:0006629 ... For each group, a list of included tissues is accessed by clicking on group name, group symbol, RNA bar, or protein bar. ... Platelet-activating factor acetylhydrolase IB subunit gamma A0A024R0L6 [Target identity:100%; Query identity:100%]. Platelet- ... GO:0004623 [phospholipase A2 activity]. GO:0005515 [protein binding]. GO:0005737 [cytoplasm]. GO:0005829 [cytosol]. GO:0006629 ...http://www.proteinatlas.org/ENSG00000079462-PAFAH1B3/tissue/vulva%252Fanal+skin
KEGG SSDB Paralog Search Result: gga:414897
gga:107051573 phospholipase A2 group III K01047 659 115 ( -) 32 0.370 108 -, gga:418081 carbohydrate sulfotransferase 11 K01017 ... gga:101750889 platelet glycoprotein Ib alpha chain-like K06261 730 154 ( -) 41 0.262 237 -, gga:107050448 chromodomain-helicase ... gga:374131 nuclear receptor subfamily 3 group C member K08555 981 177 ( -) 46 0.264 250 -, gga:421154 myosin binding protein H ... gga:396055 homeobox A2 K09302 375 138 ( -) 37 0.309 123 -, gga:107050242 leucine-rich repeat extensin-like protein 221 137 ...http://www.kegg.jp/ssdb-bin/ssdb_paralog?org_gene=gga:414897
Coagulation - Wikipedia
The calcium activates protein kinase C, which, in turn, activates phospholipase A2 (PLA2). PLA2 then modifies the integrin ... In 1957, an American group identified the same factor in a Mr. Rufus Stuart. Factors XI and XIII were identified in 1953 and ... In this disease, there is a defect in von Willebrand factor (vWF), which mediates the binding of glycoprotein Ib (GPIb) to ... Vitamin K is an essential factor to a hepatic gamma-glutamyl carboxylase that adds a carboxyl group to glutamic acid residues ...https://en.wikipedia.org/wiki/Coagulation
Additional Resources | Nutrasource Diagnostics Inc.
High Lipoprotein-Associated Phospholipase A2 is a Risk Factor for Recurrent Coronary Events in Postinfarction Patients. ... Lemaitre RN, King IB, Mozaffarian D, Kuller LH, Tracey RP, Siscovick DS. n-3 Polyunsaturated Fatty Acids, Fatal Ischemic Heart ... West of Scotland Coronary Prevention Study Group (WOSCOPS). New England Journal of Medicine 2000: 343: 1148-1155. ... Lipoprotein-Associated Phospholipase A2 and Risk of Stroke. American Journal of Cardiology 2008; 101[Suppl]: 34F-40F. ...http://nutrasource.ca/human-diagnostics/additional-resources.aspx
Lipoprotein-associated phospholipase A2, C-reactive protein, and coronary artery disease in individuals with type 1 diabetes ... Orchard TJ, Backlund JYC, Costacou T, Cleary P, Lopes-Virella M, Levy AP, Lachin JM, and the DCCT/EDIC Research Group. ... Costacou T, Ma B, King IB, Mayer-Davis EJ. Plasma and dietary vitamin E in relation to insulin secretion and sensitivity. ... Trichopoulou A, Naska A, Costacou T, DAFNE III Group. Disparities in food habits across Europe. The Proceedings of the ...https://www.publichealth.pitt.edu/home/directory/tina-costacou
The Ubiquitin-CXCR4 Axis Plays an Important Role in Acute Lung Infection-Enhanced Lung Tumor Metastasis | Clinical Cancer...
Group V phospholipase A2 in bone marrow-derived myeloid cells and bronchial epithelial cells promotes bacterial clearance after ... Mink IB, *Pickren JW. . Causes of death in cancer patients. J Med 1975;6:61-4. ... Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated ... Differences between groups were determined using the Student t test unless otherwise noted. All statistical tests were two- ...http://clincancerres.aacrjournals.org/content/19/17/4706?rss=1
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