Anti-PLA2G1B Antibody, - OriGene
phospholipase A2 group IB. Alternative Name. PLA2,PLA2A,PPLA2. Database Link. NP_000919 Entrez Gene 5319 Human. Entrez Gene ... Phospholipase A2 (EC 126.96.36.199) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known varieties are ... One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Other forms of PLA2 have been ...http://www.origene.com/antibody/TA302575.aspx
Purification and biochemical characterization of pancreatic phospholipase A2 from the common stingray Dasyatis pastinaca.
Mammalian sPLA2-IB are well characterized. In contrast, much less is known about aquatic ones. The aquatic world contains a ... Group IB Phospholipases A2 / isolation & purification*, metabolism. Hydrogen-Ion Concentration. Kinetics. Pancreas / enzymology ... ostrich phospholipase A2; PLA2: phospholipase A2; SPLA2: stingray phospholipase A2, sPLA2-IB: secreted pancreatic phospholipase ... Kolko M,Prause JU,Bazan NG,Heegaard S,Human secretory phosp holipase A(2), group IB in normal eyes and in eye diseasesActa ...http://www.biomedsearch.com/nih/Purification-biochemical-characterization-pancreatic-phospholipase/21329523.html
PLA2G1B - PrimePCR Assay and Template | Life Science | Bio-Rad
phospholipase A2, group IB (pancreas) Assay Type: EvaGreen Application: Gene Expression Unique Assay ID: dHsaEG5016521 Info: EG ... phospholipase A2, group IB (pancreas) Assay Type: Probe Application: Gene Expression Unique Assay ID: dHsaCPE5048690 Info: FAM ... phospholipase A2, group IB (pancreas) Assay Type: Probe Application: Gene Expression Unique Assay ID: dHsaCPE5048691 Info: HEX ... phospholipase A2, group IB (pancreas) Assay Type: SYBR® Green Assay Design: Intron-spanning Application: Gene Expression Unique ...http://www.bio-rad.com/en-us/prime-pcr-assays/gene/pla2g1b-human
Most recent papers with the keyword PMN | Read by QxMD
BACKGROUND: Serum secretory phospholipase A2 group IB (sPLA2-IB) is involved in the pathological processes of membranous ... Serum secretory phospholipase A2 group IB correlates with the severity of membranous nephropathy. ... www.readbyqxmd.com/read/29649452/serum-secretory-phospholipase-a2-group-ib-correlates-with-the-severity-of-membranous- ... The five groups were sacrificed on the 8th day, while the others were sacrificed on the 15th day. Two groups of albino rats ...https://www.readbyqxmd.com/keyword/84513
PLA2G1B - Wikipedia
"Entrez Gene: PLA2G1B phospholipase A2, group IB (pancreas)". Sæle O, Nordgreen A, Olsvik PA, Hamre K (2010). "Characterisation ... Phospholipase A2, group 1B is an enzyme that in humans is encoded by the PLA2G1B gene. Phospholipase A2 (EC 188.8.131.52) catalyzes ... and expression of secretory phospholipase A2 group IB during ontogeny of Atlantic cod ( Gadus morhua)". Br J Nutr. 105 (2): 1- ... "Diversity of group types, regulation, and function of phospholipase A2". J Biol Chem. 269 (18): 13057-60. PMID 8175726. " ...https://en.wikipedia.org/wiki/PLA2G1B
KEGG BRITE: KEGG Orthology (KO) - Falco peregrinus (peregrine falcon)
101912549 PLA2G1B; phospholipase A2 group IB 101923873 PLA2G12B; phospholipase A2 group XIIB 101923379 phospholipase A2 ... phospholipase A2 group XIIA 101923767 group 10 secretory phospholipase A2-like 101918580 PLA2G4A; phospholipase A2 group IVA ... phospholipase A2 group IVC 101925028 PLA2G4F; phospholipase A2 group IVF 101924845 cytosolic phospholipase A2 epsilon-like ... 101922643 PLA2G4B; cytosolic phospholipase A2 beta 101918608 PLA2G6; phospholipase A2 group VI 101915961 PLB1; phospholipase B1 ...http://www.genome.jp/kegg-bin/get_htext?fpg00001+101919862
Purification and biochemical characterization of a secreted group IIA chicken intestinal phospholipase A2 | Springer for...
Background Secretory phospholipase A2 group IIA (IIA PLA2) is a protein shown to be highly expressed in the intestine of ... Exogenously added human group X secreted phospholipase A(2) but not the group IB, IIA, and V enzymes efficiently release ... Nevalainen TJ, Haapanen TJ: Distribution of pancreatic (group I) and synovial-type (group II) phospholipases A2 in human ... Role of group IIA phospholipase A2. J Clin Invest. 1998, 102 (3): 633-638. 10.1172/JCI3121PubMedCentralCrossRefPubMedGoogle ...https://rd.springer.com/article/10.1186/1476-511X-10-27
Constitutive and Lysophosphatidic Acid (LPA)-induced LPA Production: Role of Phospholipase D and Phospholipase A2 | Clinical...
Both the group IIA sPLA2 inhibitor manoalide and the group IB sPLA2 inhibitor OOEPC reduced LPA-induced production of LPA by ∼ ... Group IB (pancreatic) secretory PLA2 plays a critical role in both constitutive and LPA-induced LPA formation, whereas group ... Inhibitors of PLD, pancreatic (group IB) sPLA2 and cPLA2/iPLA2, but not a nonpancreatic (group IIA) sPLA2, inhibitor block LPA- ... Inhibitors of PLD, pancreatic (group IB) sPLA2 and cPLA2/iPLA2, but not a nonpancreatic (group IIA) sPLA2 inhibitor block ...http://clincancerres.aacrjournals.org/content/6/6/2482
Orientations of Proteins in Membranes (OPM) database
4p2p » Phospholipase A2, group IB See all membrane protein images in OPM ...http://opm.phar.umich.edu/?family=24
Lincosamide resistance protein elisa and antibody
phospholipase A2, group IB (pancreas) (PLA2G1B) ELISA Kit. • OCT4 ELISA Kit. • N(4)-(Beta-N-Acetylglucosam inyl)-L-Asparaginase ...https://www.mybiosource.com/protein_family.php?root=lincosamide-resistance-protein
KEGG PATHWAY: hsa00564
PLA2G12B; phospholipase A2 group XIIB [KO:K01047] [EC:184.108.40.206]. 5319 PLA2G1B; phospholipase A2 group IB [KO:K01047] [EC:220.127.116.11 ... PLA2G16; phospholipase A2 group XVI [KO:K16817] [EC:18.104.22.168 22.214.171.124] ... PNPLA6; patatin like phospholipase domain containing 6 [KO:K14676] [EC:126.96.36.199] ... PNPLA7; patatin like phospholipase domain containing 7 [KO:K14676] [EC:188.8.131.52] ...http://www.genome.jp/dbget-bin/www_bget?pathway+hsa00564
Gentaur Molecular :Biovis \ Octyl-β-D-thioglucopyranoside \ 1782-50G
PLA2G1B PLA2 PLA2A PPLA2] Phospholipase A2 (EC 184.108.40.206) (Group IB phospholipase A2) (Phosphatidylcholine 2-acylhydrolase 1B). [ ... BRCA2 FACD FANCD1] Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein). [ABO] Histo-blood group ABO ... Histo-blood group A transferase) (A transferase) (Histo-blood group B transferase) (B transferase) (NAGAT) [Cleaved into: ... PPARG NR1C3] Peroxisome proliferator-activated receptor gamma (PPAR-gamma) (Nuclear receptor subfamily 1 group C member 3). [ ...http://www.antibody-antibodies.com/product_det.php?id=1772565&supplier=search&name=Octyl_%CE%B2_D_thioglucopyranoside
Prof. Saul Yedgar | imric.org
... invasiveness are regulated by Group IB secretory Phospholipase A2 receptor-mediated activation of cytosolic Phospholipase A2. ... Role of phospholipase A2 in inflammatory/allergic processes: Phospholipase A2 (PLA2), which hydrolyzes cell membrane ... Our research group includes two teams: One team studies the role of phospholipase A2 (PLA2) in inflammtory/allergic processes, ... Control of Phospholipase A2 activities for the treatment of inflammatory conditions. Aggregation of red blood cells in patients ...http://www.imric.org/research/researchers/prof-saul-yedgar
JCI - Volume 104, Issue 5
Although mammalian pancreatic group IB and inflammatory-type group IIA sPLA2s were inactive against HIV-1 replication, our ... Mammalian and venom secreted phospholipases A2 (sPLA2s) have been associated with a variety of biological effects. Here we show ... Secreted phospholipases A2, a new class of HIV inhibitors that block virus entry into host cells. ... Secreted phospholipases A2, a new class of HIV inhibitors that block virus entry into host cells. ...https://jci.org/104/5
Immune response - CCR3 signaling in eosinophils Pathway Map - PrimePCR | Life Science | Bio-Rad
Cloning and expression of cystolic phospholipase A2 (cPLA2) and a naturally occurring variant. Phosphorylation of Ser505 of ... PI3K class IB)/ PDK(PDPK1)/ PKC-zeta/ H-Ras/ c-Raf-1/ MEK1/2 kinases (MAPK/ERK) pathway , . Although the upstream ... Chemokines of the eotaxin group (Eotaxin, Eotaxin-2, and Eotaxin-3), acting exclusively via CCR3, induce recruitment of ... Cloning and expression of cystolic phospholipase A2 (cPLA2) and a naturally occurring variant. Phosphorylation of Ser505 of ...http://www.bio-rad.com/en-us/prime-pcr-assays/pathway/immune-response-ccr3-signaling-eosinophils
Human Metabolome Database: Showing metabocard for LysoPC(22:1(13Z)) (HMDB0010399)
4. Group IIF secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ... Platelet-activating factor acetylhydrolase IB subunit gamma. General function:. Involved in hydrolase activity. Specific ... 9. Group IIE secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ... 8. Group 10 secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ...http://www.hmdb.ca/metabolites/HMDB10399
A2 - Wikipedia
... an Afro-Asiatic family of languages spoken in Nigeria A2, a second language level in the IB Group 2 subjects A2, a level in the ... a protein Apolipoprotein A2, a protein Phospholipase A2, an enzyme Prokaryotic phospholipase A2, an enzyme Hemoglobin A2, a ... A2, A02, A002, A², A.II or A-2 may refer to: A2 Racer, a racing computer game series A2 - Secret of the Slavers Stockade, a ... A2, a variant of blood groups alleles A in the ABO blood group system A-box 2 of insulin gene HLA-A2, a human MHC HLA-A ...https://en.wikipedia.org/wiki/A2
Human Metabolome Database: Showing metabocard for PC(16:0/22:5(7Z,10Z,13Z,16Z,19Z)) (HMDB0007990)
4. Group 10 secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ... Probable phospholipid-transporting ATPase IB. General function:. Involved in ATP binding. Specific function:. ATP + H(2)O + ... Group XIIA secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ... Group IIF secretory phospholipase A2. General function:. Involved in phospholipase A2 activity. Specific function:. PA2 ...http://www.hmdb.ca/metabolites/HMDB07990
Anthera Announces Preliminary Positive Results From Once-Daily A-002 Phase II Cardiovasc... ( SAN MATEO Calif. Jan. 15 /-...
The primary endpoint was reduction in secretory phospholipase A2 (sPLA2) levels. Secondary endpoints included a number of lipid ... Announces Successful Phase Ib Results for DOV 21,947. 9. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical ... a group of enzymes responsible for the release of arachidonic acid and subsequent production of leukotrienes prostacyclins and ... to a series of clinical and pre-clinical compounds that inhibit the enzymatic activity of members of the phospholipase A2 (PLA2 ...http://www.bio-medicine.org/medicine-technology-1/Anthera-Announces-Preliminary-Positive-Results-From-Once-Daily-A-002-Phase-II-Cardiovascular-Trial-1202-1/
Human Metabolome Database: Showing metabocard for LysoPC(10:0) (HMDB0003752)
Membrane-associated phospholipase. Exhibits a calcium-independent broad substrate specificity including phospholipase A2/ ... Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Gene Name:. PAFAH1B2. Uniprot ... 4. Platelet-activating factor acetylhydrolase IB subunit gamma. General function:. Involved in hydrolase activity. Specific ... 1. Cytosolic phospholipase A2. General function:. Involved in metabolic process. Specific function:. Selectively hydrolyzes ...http://www.hmdb.ca/metabolites/HMDB03752
phospholipase A2, group IIA (platelets, synovial fluid) /// phospholipase A2, group IIA (platelets, synovial fluid). 0.0139. ... alcohol dehydrogenase IB (class I), beta polypeptide. 0.0177. 0.9993. Hs.370704. ---. CDNA FLJ36685 fis, clone UTERU2008018. ... phospholipase A1 member A /// phospholipase A1 member A. 0.0151. 0.9995. Hs.2316. SOX9. SRY (sex determining region Y)-box 9 ( ... phospholipase C, delta 4 /// phospholipase C, delta 4. -0.0088. 0.0002. Hs.64313. FLJ36748. hypothetical protein FLJ36748. - ...http://cmgm.stanford.edu/~kimlab/aging_muscle/supp_table_2.htm
Molecular Interactions Leading to Lipoprotein Retention and the Initiation of Atherosclerosis | Arteriosclerosis, Thrombosis,...
LDL treatment with phospholipase A2 increased its binding.52 A neighboring region to site B, site A (residues 3148 to 3158), ... The observed interactions were interpreted as an ionic binding of positively charged amino groups on apoB to negatively charged ... B-Ib at residues 84 to 94) located in the amino terminus of apoB is masked by the carboxyl terminus of apoB100 in apoB100- ... The modifications include lipolysis by sphingomyelinases or phospholipases,89 or complexation to proteoglycans.90 In addition, ...http://atvb.ahajournals.org/content/24/12/2211
Toxins | Free Full-Text | Molecular Characterization of Lys49 and Asp49 Phospholipases A2 from Snake Venom and Their Antiviral...
Group IA), and pancreatic svPLA2s (Group IB), while group II is found abundantly in the venom of viperidae snakes [5,7]. The ... Scott, D.L. Phospholipase A2 Structure and Catalytic Properties. In Venom Phospholipase A2 Enzymes, Structure; Function and ... On the other hand, group II differs from group I in having an extended C-terminal tail [6,8]. ... The thiol groups of purified proteins (1.5 mg each) were S-reduced and alkylated with vinyl pyridine as described . The ...http://www.mdpi.com/2072-6651/5/10/1780/htm
IJMS | Free Full-Text | Lipid Based Therapy for Ulcerative Colitis-Modulation of Intestinal Mucus Membrane Phospholipids as a...
Fabia, R; Ar'Rajab, A; Willen, R; Andersson, R; Bengmark, S. Effect of putative phospholipase A2 inhibitors on acetic acid- ... Einerhand, AW; Renes, IB; Makkink, MK; van der Sluis, M; Buller, HA; Dekker, J. Role of mucins in inflammatory bowel disease: ... Crohn's Disease cA2 Study Group. N. Engl. J. Med 1997, 337, 1029-1035. [Google Scholar] ... Yedgar, S; Cohen, Y; Shoseyov, D. Control of phospholipase A2 activities for the treatment of inflammatory conditions. Biochim ...http://www.mdpi.com/1422-0067/11/10/4149/htm
Deficiency of Cbl-b Gene Enhances Infiltration and Activation of Macrophages in Adipose Tissue and Causes Peripheral Insulin...
Interestingly, expression of phospholipase A2-IB (PLA2-IB), a lipolytic enzyme associated with fatty liver (35), was ... Data are means ± SD (n = 4/group/experiment). *P , 0.05 compared with 4-week-old Cbl-b−/− mice. Scale = 100 μm. C: Serial ... In a group of 20-week-old littermates, 25 μg anti-monocyte chemoattractant protein-(MCP)-1 antibody or nonimmune IgG (R&D ... There is no report, to our knowledge, that MCP-1 downregulates expression of PLA2-IB, although MCP-1 has been reported to ...http://diabetes.diabetesjournals.org/content/56/10/2511.full