Glutathione S-Transferase pi 1/GSTP1 Products: R&D Systems
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Glutathione S-transferase Pi expression predicts response to adjuvant chemotherapy for stage C colon cancer: a matched...
This result was unaffected by GST Pi genotype. Stage C colon cancer patients with low GST Pi did not benefit from 5- ... GST Pi expression was assessed by immunohistochemistry. Overall survival was analysed by the Kaplan-Meier method and Cox ... Survival did not differ significantly among patients with low GST Pi who did or did not receive chemotherapy and those with ... high GST Pi who received chemotherapy (lowest pair-wise p = 0.11) whereas patients with high GST Pi who did not receive ...
Glutathione S-transferase - Wikipedia
Therefore, if a human glutathione S-transferase is a homodimer in the pi-class subfamily 1, its name will be written as "hGSTP1 ... Affinity chromatography Bacterial glutathione transferase Glutathione S-transferase Mu 1 Glutathione S-transferase, C-terminal ... Overview of Glutathione S-Transferases Glutathione+S-Transferase at the U.S. National Library of Medicine Medical Subject ... Sundberg AG, Appelkvist EL, Bäckman L, Dallner G (1994). "Urinary pi-class glutathione transferase as an indicator of tubular ...
Kinome and phosphoproteome of high-grade meningiomas reveal AKAP12 as a central regulator of aggressiveness and its possible...
dihydrolipoic acid - Ontology Report - Rat Genome Database
Methylation profile of the promoter CpG islands of 14 “drug-resistance” genes in hepatocellular carcinoma
Pi-class glutathione S-transferase: regulation and function. Chem Biol Interact. 1998;111-112:69-82. [PubMed] [DOI] [Cited in ... Methyl-CpG binding domain protein 2 represses transcription from hypermethylated pi-class glutathione S-transferase gene ... Glutathione-S-transferases (GSTs) are a family of phase II detoxification enzymes that catalyze the conjugation of glutathione ... Both glutathione S-transferase pi (GSTpi) (80%, 24/30 in tumor and 56.7%, 17/30 in the paired non-cancerous tissues) and cystic ...
GSTP1 Monoclonal Antibody (OTI10H1) (TA801776)
Glutathione S-transferase P; GST class-pi; GSTP1-1; HGNC:4638 ... Glutathione S-transferases (GSTs) are a family of enzymes that ... glutathione transferase activity glutathione peroxidase activity protein binding drug binding JUN kinase binding kinase ... glutathione metabolic process xenobiotic metabolic process central nervous system development negative regulation of ... pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that ...
IFN-β Down-Regulates the Expression of DNA Repair Gene MGMT and Sensitizes Resistant Glioma Cells to Temozolomide | Cancer...
Novel Biomarkers of Kidney Function: Introduction and Overview, Characteristics of an Ideal Marker for Kidney Disease,...
Glutathione-s-transferase (GST). GST represents a family of cytosolic, microsomal, and membrane-bound enzymes. The GST alpha ... isoform is localized in the proximal tubular cells, while the pi isoform is confined to distal tubular cells. Increased levels ... Distribution of glutathione S-transferase isoenzymes in human kidney: basis for possible markers of renal injury. J Clin Pathol ... along with alpha-glutathione-s-transferase (GST), were able to predict future development of stages 1 and 3 AKI. [44] In a ...
SCOPe 2.08: Domain d6gssb1: 6gss B:77-209
PDB Description: human glutathione s-transferase p1-1, complex with glutathione. PDB Compounds: (B:) glutathione s-transferase ... d6gssb1 a.45.1.1 (B:77-209) Class pi GST {Human (Homo sapiens) [TaxId: 9606]} ... Family a.45.1.1: Glutathione S-transferase (GST), C-terminal domain [47617] (19 proteins). ...
Resveratrol protects against arsenic trioxide-induced nephrotoxicity by facilitating arsenic metabolism and decreasing...
Lo JF, Wang HF, Tam MF, Lee TC (1992) Glutathione S-transferase pi in an arsenic-resistant Chinese hamster ovary cell line. ... and null genotypes of glutathione S-transferase M1 and T1 among current arsenic-exposed residents in Taiwan. Mutat Res 386:197- ... the ratio of reduced glutathione to oxidized glutathione, the total arsenic concentrations, and the percentage of methylated ... Hayakawa T, Kobayashi Y, Cui X, Hirano S (2005) A new metabolic pathway of arsenite: arsenic-glutathione complexes are ...
Potential of the ellagic acid-derived gut microbiota metabolite - Urolithin A in gastrointestinal protection
NIOSHTIC-2 Search Results - Basic View
Nutrients | Free Full-Text | Skin Carotenoids in Public Health and Nutricosmetics: The Emerging Roles and Applications of the...
13gs.1 | SWISS-MODEL Template Library
Oakley, A.J. et al., The Ligandin (Non-Substrate) Binding Site of Human Pi Class Glutathione Transferase is Located in the ... GLUTATHIONE S-TRANSFERASE COMPLEXED WITH SULFASALAZINE Coordinates. PDB Format Method. X-RAY DIFFRACTION 1.90 Å. Oligo State. ... 2 x GSH: GLUTATHIONE(Non-covalent). GSH.1: 13 residues within 4Å:*. Chain A: Y.8, F.9, R.14, W.39, K.45, G.51, Q.52, L.53, P.54 ...
Cytochrome P450 expression in oesophageal cancer. | Gut
... and glutathione S-transferase pi were expressed in at least 60% of samples. The expression of glutathione S-transferases alpha ... non-neoplastic samples and tumour samples except the CYP3A was also identified in mast cells and glutathione S-transferase pi ... Epoxide hydrolase was present in half of the non-neoplastic samples and the different classes of glutathione S-transferase were ... of different forms of P450 and the functionally associated enzymes epoxide hydrolase and glutathione S-transferases have been ...
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Immunology of hepatocellular carcinoma
"Hidden Glutathione Transferases in the Human Genome" by Aaron J. Oakley
Multiple resistant Alopecurus myosuroides from Sweden
HRAC Group 3</b> <font size='2'> (Legacy K1) </font> resistant Alopecurus myosuroides...
HRAC Group 1</b> <font size='2'> (Legacy A) </font> resistant Alopecurus...
GSTO2 | Cancer Genetics Web
Human cytosolic glutathione-S-transferases (GSTs) include several classes such as alpha (A), mu (M), pi (P), sigma (S), zeta (Z ... MATERIAL AND METHODS: We compared the genotypes of Glutathione S-Transferase mu, theta, pi and omega (GSTM1, GSTT1, GSTP1 and ... glutathione dehydrogenase (ascorbate) activity - glutathione transferase activity - L-ascorbic acid metabolic process - ... METHODS: The promoter regions of 23 genes of the glutathione S-transferase (GST) and glutathione peroxidase (GPX) families were ...
SciELO - Brazil - Polymorphisms associated with the risk of lung cancer in a healthy Mexican Mestizo population: application...
... at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer. ... glutathione transferases GSTM1, GSTT1 and GSTP1 (Sobti et al., 2008), N-acetyl transferase 2 (NAT2) and epoxide hydrolase ( ... Mohr L, Rodgers K and Silvestri G (2003) Glutathione S-transferase M1 polymorphism and the risk of lung cancer. Anticancer Res ... Salam M, Lin P, Avol E, Gauderman J and Gilliland F (2007) Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic ...
Interaction between gas cooking and GSTM1 null genotype in bronchial responsiveness: results from the European Community...
15 Variants in genes encoding glutathione-S-transferase mu 1 (GSTM1), theta 1 (GSTT1) and pi 1 (GSTP1) have been linked to ... Effects of glutathione-S-transferase M1, T1, and P1 on childhood lung function growth. Am J Respir Crit Care Med 2002;166:710- ... Glutathione S-transferase variants and their interaction with smoking on lung function. Am J Respir Crit Care Med 2004;170:388- ... Glutathione S-transferase M1 and P1 genotype, passive smoking, and peak expiratory flow in asthma. Pediatrics 2006;118:710-16. ...