*  British Library EThOS: Analysis of class I MHC genes in cattle
The aim of this project was to isolate a functional BoLA class I gene, to transfect this into L cells and to investigate the ... This library was made from animal 10769 which has BoLA type w10/w11 and the genes were identified with a class I cDNA probe, ... Therefore a functional BoLA class I gene with a BoLA type w11 was isolated and is a stepping stone to many other investigations ... Attempts to isolate a functional BoLA class I gene from a cosmid library were unsuccessful, but clones encoding complete BoLA ...
  http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.652212
*  Identification, inheritance, and linkage of B-G-like and MHC class I genes in cranes
MHC). We evaluated the inheritance of B-G-like genes in families of whooping and Florida sandhill cranes using restriction ... The fully sequenced wcbg2 gene encodes a B-G IgV-like domain, an additional Ig-like domain, a transmembrane domain, and a ... Segregation of RFPs in families of Florida sandhill cranes provide evidence for genetic polymorphism in the B-G-like genes. The ... of restriction fragments in DNA from the whooping crane and from a number of other species indicate that the B-G-like gene ...
  https://pubs.er.usgs.gov/publication/5223333
*  Natural selection on marine carnivores elaborated a diverse family of classical MHC class I genes exhibiting haplotypic gene...
The MHC class I genes of the rhesus monkey. Different evolutionary histories of MHC class I and II genes in primates. J Immunol ... The second, a candidate nonclassical MHC class I gene, comprises a nonpolymorphic transcribed gene related to dog DLA-79 and ... Yuhki N, O'Brien SJ (1988) Molecular characterization and genetic mapping of class I and class II MHC genes of the domestic cat ... Natural selection on marine carnivores elaborated a diverse family of classical MHC class I genes exhibiting haplotypic gene ...
  https://link.springer.com/article/10.1007/s00251-012-0651-z
*  Toxins | Free Full-Text | MHC Class II and Non-MHC Class II Genes Differentially Influence Humoral Immunity to Bacillus...
Here, we investigated the relative contribution of MHC class II versus non-MHC class II genes in the humoral response to PA and ... Conversely, the humoral fine specificity of reactivity to LF appeared to be controlled primarily through non-MHC class II genes ... H-2k at the MHC class II locus), B6 (H-2b), and B6.H2k (H-2k). IgG antibody titers to LF were controlled primarily by the MHC ... with both MHC class II and other genes playing roles. ... These results demonstrate that MHC class II differentially ...
  http://www.mdpi.com/2072-6651/4/12/1451
*  The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin...
MHC class II (MHC-II) genes encode cell-surface glycoproteins that present antigens to CD4 T cells to initiate and control ... Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte ... Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA. Science. 265:106-108. ... Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes. Eur. J. Immunol. 34:1513-1525. ...
  http://jem.rupress.org/content/205/4/785
*  Non-neutral evolution and reciprocal monophyly of two expressed Mhc class II B genes in Leach's storm-petrel. | Sigma-Aldrich
Non-neutral evolution and reciprocal monophyly of two expressed Mhc class II B genes in Leach's storm-petrel.. [Donald C ... We characterized two Mhc class II B loci in Leach's storm-petrel, Oceanodroma leucorhoa, focusing on exon 2 which encodes the ... Unlike many studies of duplicated Mhc genes, alleles of the two loci clustered into monophyletic groups. Consistent with this ... Overall, the results suggest that the gene duplication event leading to these two loci is not recent and that point mutations ...
  https://www.sigmaaldrich.com/catalog/papers/25416539
*  MHC Class I Chain-Related Gene A Diversity in Patients with Cutaneous Malignant Melanoma from Southeastern Spain
... José Antonio ... of the major histocompatibility complex class I chain-related gene A (MICA) in patients with melanoma. However, the influence ... Patients were classified according to the presence of methionine or valine at codon 129 of MICA gene. We found a high frequency ...
  https://www.hindawi.com/journals/dm/2015/831864/abs/
*  Regulation of MHC Class II Genes - Jeremy Boss
MHC-II genes are expressed in a tissue-specific manner and are regulated both developmentally and by the actions of immune ... 2012) CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments. Genes ... Regulation of MHC Class II Genes Boss, Jeremy M. Emory University, Atlanta, GA, United States ... interact directly with active MHC-II promoters that have the MHC-II master regulator CIITA bound. MHC-II gene transcription and ...
  http://grantome.com/grant/NIH/R01-GM047310-19
*  Publication - Targeted disruption of the MHC class II Aa gene in C57BL/6 mice.
The MHC class II gene Aa was disrupted by targeted mutation in embryonic stem (ES) cells derived from C57BL/6 mice to prevent ... Targeted disruption of the MHC class II Aa gene in C57BL/6 mice.. Kontgen, F; Suss, G; Stewart, C; Steinmetz, M; Bluethmann, H ... The B6-Aa0/Aa0 mutant mice described in this study represent an important tool to investigate the involvement of MHC class II ... The complete lack of cell surface expression of MHC class II molecules in B6-Aa0/Aa0 homozygous mutant mice was directly ...
  https://www.ozgene.com/publication/papers?view=publication&task=show&id=2
*  does MHC class III genes encode Interleukin Beta microglobulinc Tumor necro
... MHC class III genes encodes proteins of classic and ... does MHC class III genes encode Interleukin Beta microglobulinc Tumor necrosis factor Complement component MHC class III genes ... random - major role HLA class III region genes Immune surveillanceb Transplant .... *random - does MHC class III genes encode ... disease Class III genes not participate MHC restriction graft rejection components Many proteins coded MHC class III genes may ...
  http://mbbsdost.com/Autosomal-dominant-disorders-Mnemonic/medical/does-MHC-class-III-genes-encode-Interleukin-Beta-microglobulinc-Tumor-necro/random-mcqs-questions/
*  HLA-DRB1 - MHC class II antigen - Homo sapiens (Human) - HLA-DRB1 gene & protein
IPR011162. MHC_I/II-like_Ag-recog. IPR014745. MHC_II_a/b_N. IPR000353. MHC_II_b_N. ... IPR011162. MHC_I/II-like_Ag-recog. IPR014745. MHC_II_a/b_N. IPR000353. MHC_II_b_N. ... MHC class II antigenImported. ,p>Information which has been imported from another database using automatic procedures.,/p> ,p>, ... tr,F4YZW3,F4YZW3_HUMAN MHC class II antigen (Fragment) OS=Homo sapiens OX=9606 GN=HLA-DRB1 PE=4 SV=1 ...
  http://www.uniprot.org/uniprot/F4YZW3
*  HLA-B - MHC class I antigen - Homo sapiens (Human) - HLA-B gene & protein
IPR011161. MHC_I-like_Ag-recog. IPR037055. MHC_I-like_Ag-recog_sf. IPR011162. MHC_I/II-like_Ag-recog. IPR001039. MHC_I_a_a1/a2 ... IPR011161. MHC_I-like_Ag-recog. IPR037055. MHC_I-like_Ag-recog_sf. IPR011162. MHC_I/II-like_Ag-recog. IPR001039. MHC_I_a_a1/a2 ... MHC class I antigenImported. ,p>Information which has been imported from another database using automatic procedures.,/p> ,p>,a ... Belongs to the MHC class I family.UniRule annotation. ,p>Information which has been generated by the UniProtKB automatic ...
  http://www.uniprot.org/uniprot/I2B2W9
*  HLA-B - MHC class I antigen - Homo sapiens (Human) - HLA-B gene & protein
IPR003006. Ig/MHC_CS. IPR003597. Ig_C1-set. IPR011161. MHC_I-like_Ag-recog. IPR037055. MHC_I-like_Ag-recog_sf. IPR011162. MHC_I ... IPR003006. Ig/MHC_CS. IPR003597. Ig_C1-set. IPR011161. MHC_I-like_Ag-recog. IPR037055. MHC_I-like_Ag-recog_sf. IPR011162. MHC_I ... MHC class I antigenImported. ,p>Information which has been imported from another database using automatic procedures.,/p> ,p>,a ... Belongs to the MHC class I family.UniRule annotation. ,p>Information which has been generated by the UniProtKB automatic ...
  http://www.uniprot.org/uniprot/J7QJV5
*  Santa J. Ono - Wikipedia
... the work mapped susceptibility genes in the BB rat to the class II MHC loci. His work also showed that class I and II MHC gene ... Enhanced MHC class I heavy-chain gene expression in pancreatic islets". Diabetes. 37 (10): 1411-8. doi:10.2337/diabetes.37.10. ... He focused much of his research in the next decade on the regulation of MHC gene expression. He showed that the different class ... Abdulkadir SA; Ono SJ (November 1995). "How are class II MHC genes turned on and off?". The FASEB Journal. 9 (14): 1429-35. ...
  https://en.wikipedia.org/wiki/Santa_J._Ono
*  RFX2 - Wikipedia
"The genes for MHC class II regulatory factors RFX1 and RFX2 are located on the short arm of chromosome 19". Genomics. 13 (4): ... "Entrez Gene: RFX2 regulatory factor X, 2 (influences HLA class II expression)". Reith W, Ucla C, Barras E, et al. (1994). "RFX1 ... This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly- ... The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional ...
  https://en.wikipedia.org/wiki/RFX2
*  RFX1 - Wikipedia
MHC class II regulatory factor RFX1 is a protein that, in humans, is encoded by the RFX1 gene located on the short arm of ... This protein binds to the Xboxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted ... found in all MHC class II genes. Levels of mRNA encoding this protein as well as RFX2 and RFX3 are found to be consistently ... "The genes for MHC class II regulatory factors RFX1 and RFX2 are located on the short arm of chromosome 19". Genomics. 13 (4): ...
  https://en.wikipedia.org/wiki/RFX1
*  RFXAP - Wikipedia
1997). "Mutation of RFXAP, a regulator of MHC class II genes, in primary MHC class II deficiency". N. Engl. J. Med. 337 (11): ... Mach B, Steimle V, Martinez-Soria E, Reith W (1996). "Regulation of MHC class II genes: lessons from a disease". Annu. Rev. ... which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been ... 1999). "RFX-B is the gene responsible for the most common cause of the bare lymphocyte syndrome, an MHC class II ...
  https://en.wikipedia.org/wiki/RFXAP
*  HLA-F - Wikipedia
The MHC proteins are classified into three main categories, namely class I, II, and III. There are over 140 genes within the ... and C are the classical class I genes and HLA-E, F and G are the nonclassical class I genes. The protein encoded from the gene ... Howcroft TK, Strebel K, Martin MA, Singer DS (May 1993). "Repression of MHC class I gene promoter activity by two-exon Tat of ... Lury D, Epstein H, Holmes N (1991). "The human class I MHC gene HLA-F is expressed in lymphocytes". International Immunology. 2 ...
  https://en.wikipedia.org/wiki/HLA-F
*  NLRC5 - Wikipedia
"NLR family member NLRC5 is a transcriptional regulator of MHC class I genes". Proc. Natl. Acad. Sci. 107 (31): 13794-13799. doi ... "NLRC5 Deficiency Selectively Impairs MHC Class I-Dependent Lymphocyte Killing by Cytotoxic T Cells". J Immunol. 188 (8): 3820-8 ... NLRC5 localizes to the nucleus and drives MHCI gene expression by occupying H-2D and H-2K gene promoters. In humans, the NLRC5 ... Recently, NLRC5 has been suggested to play a positive role in the regulation of Major Histocompatibility Class I (MHCI) ...
  https://en.wikipedia.org/wiki/NLRC5
*  HLA-DMA - Wikipedia
Fling SP, Arp B, Pious D (1994). "HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in ... "Second proteasome-related gene in the human MHC class II region". Nature. 353 (6345): 667-8. doi:10.1038/353667a0. PMID 1922385 ... "The impact of the non-classical MHC proteins HLA-DM and HLA-DO on loading of MHC class II molecules". Immunol. Rev. 172: 267-78 ... HLA class II histocompatibility antigen, DM alpha chain is a protein that in humans is encoded by the HLA-DMA gene. HLA-DMA ...
  https://en.wikipedia.org/wiki/HLA-DMA
*  PSMB9 - Wikipedia
This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced ... "Second proteasome-related gene in the human MHC class II region". Nature. 353 (6345): 667-8. Bibcode:1991Natur.353..667K. doi: ... is the processing of numerous MHC class-I restricted T cell epitopes. The gene PSMB9 encodes a member of the proteasome B-type ... "DNA sequence analysis of 66 kb of the human MHC class II region encoding a cluster of genes for antigen processing". Journal of ...
  https://en.wikipedia.org/wiki/PSMB9
*  CIITA - Wikipedia
MHC) class II enhanceosome, and MHC class II gene transactivation". Molecular and Cellular Biology. 20 (20): 7716-25. doi: ... "Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte ... Mach B, Steimle V, Reith W (Apr 1994). "MHC class II-deficient combined immunodeficiency: a disease of gene regulation". ... "MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers". Nature. 471 (7338): 377-81. doi: ...
  https://en.wikipedia.org/wiki/CIITA
*  HLA-DQ1 - Wikipedia
1997). "MHC class II genes influence the susceptibility to chronic active hepatitis C". J. Hepatol. 27 (2): 259-64. doi:10.1016 ... 1994). "DNA typing of HLA class II genes; DRB1*0803 increases the susceptibility of Japanese to primary biliary cirrhosis". J. ... Möller E, Carlsson B, Wallin J (1985). "Implication of structural class II gene polymorphism for the concept of serologic ... Rani R, Fernandez-Vina MA, Zaheer SA, Beena KR, Stastny P (1993). "Study of HLA class II alleles by PCR oligotyping in leprosy ...
  https://en.wikipedia.org/wiki/HLA-DQ1
*  MHC class I polypeptide-related sequence B - Wikipedia
MHC class I polypeptide-related sequence B (MICB) is a protein that is encoded by the MICB gene located within MHC locus. MICB ... Bahram S, Shiina T, Oka A, Tamiya G, Inoko H (1997). "Genomic structure of the human MHC class I MICB gene". Immunogenetics. 45 ... Braud VM, Allan DS, McMichael AJ (Feb 1999). "Functions of nonclassical MHC and non-MHC-encoded class I molecules". Current ... "Sequencing-based typing reveals six novel MHC class I chain-related gene B (MICB) alleles". Tissue Antigens. 51 (6): 649-52. ...
  https://en.wikipedia.org/wiki/MHC_class_I_polypeptide-related_sequence_B
*  ASMscience | Lyme Borreliosis
Direct enumeration of Borrelia-reactive CD4_ T cells ex vivo by using MHC class II tetramers. Proc. Natl. Acad. Sci. USA 97: ... Arthropod- and hostspecific gene expression by Borrelia burgdorferi. J. Clin. Investig. 100:S3-S5.. ... Protective antibodies develop, and murine Lyme arthritis regresses, in the absence of MHC class II and CD4_ T cells. J. Immunol ... An enhanced GFP reporter system to monitor gene expression in Borrelia burgdorferi. Microbiology 149:1819-1828.. ...
  http://www.asmscience.org/content/book/10.1128/9781555816490.chap11