Genes, Intracisternal A-Particle | Profiles RNS
Intracisternal A-Particle" by people in this website by year, and whether "Genes, Intracisternal A-Particle" was a major or ... Intracisternal A-Particle*Genes, Intracisternal A-Particle. *Genes, Intracisternal A Particle. *Intracisternal A-Particle Genes ... "Genes, Intracisternal A-Particle" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Genes, Intracisternal A-Particle" by people in Profiles. ...
Ru-Chih Chow Huang - Wikipedia
1980) "Sequence organization of clones intracisternal a particle genes." Cell 21 (2):465-473. L Hoopes, A Brown, and Ru Chih C ... 1983) Methylation and rearrangement of mouse intracisternal a particle genes in development aging and myeloma. Molecular and ... In the years that followed at Johns Hopkins, her research focused upon gene regulation in cancer, regulation of viral gene ... Later she made discoveries about the molecular biology of cancer and of viral gene regulation. Ru-Chih Chow was born April 2, ...
Frontiers | The influence of early environment and micronutrient availability on developmental epigenetic programming: lessons...
... some of which correlate with DNA methylation changes at certain genes. Animal models have shown more directly that DNA ... some of which correlate with DNA methylation changes at certain genes. Animal models have shown more directly that DNA ... heritable mark that can affect genome function and influence gene expression. Somatic DNA methylation patterns that can persist ... heritable mark that can affect genome function and influence gene expression. Somatic DNA methylation patterns that can persist ...
Brian J Bennett : USDA ARS
Ectopic expression of the Stabilin2 gene triggered by an intracisternal A particle (IAP) element in DBA/2J strain of mice. -( ... Ectopic expression of the Stabilin2 gene triggered by an intracisternal A particle (IAP) element in DBA/2J strain of mice. ... In particular he is focused on how diet affects gene expression. Dr. Bennett focuses on the role of a particular metabolite ( ... This grant from the National Heart, Lung and Blood Institute enabled him to further study how genes and diet affect ...
Simon Cook - Publications | Babraham Institute
Major satellites, intracisternal A particles (IAPs), and imprinted genes remain relatively resistant to erasure. ... underpinned by the failure to demethylate a small group of TS cell genes. Forced expression of these non-reprogrammed genes ... Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen ... Mutations and gene amplifications that confer drug resistance emerge frequently during chemotherapy, but their mechanism and ...
Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice | Nature Genetics
We also identified recurrent integrations in known and newly discovered leukemia genes including Nf1, Bach2, Dleu2 and Nup98. ... Here we report that activation of a humanized Npm1c knock-in allele in mouse hemopoietic stem cells causes Hox gene ... role of intracisternal A-particle transposition for growth factor gene activation. EMBO J. 9, 1087-1096 (1990). ... shows a distinct gene expression profile characterized by up-regulation of genes involved in stem-cell maintenance. Blood 106, ...
How to generate 'super-immunity' to nearly all known coronaviruses...
Some mammalian cells already have some viral gene sequences that are expressed (for example, look up intracisternal type A ... particles (IAPs)). It seems unwise to add an entire, ACTIVE viral genome to a cell simply to try to generate a suitable antigen ... immunizing with all the gene products is more or less the same as giving a vaccine consisting of the inactivated virus ... immunizing with all the gene products is more or less the same as giving a vaccine consisting of the inactivated virus ...
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. - CIRM
In contrast, imprinted regions and intracisternal A particle retroelements, which are resistant to demethylation in the early ... This is followed by DNA demethylation of many gene promoters and upregulation of demethylated germline genes. Tet1 binding is ... In contrast, imprinted regions and intracisternal A particle retroelements, which are resistant to demethylation in the early ... This is followed by DNA demethylation of many gene promoters and upregulation of demethylated germline genes. Tet1 binding is ...
StemTherapy: National Initiative on Stem Cells for Regenerative Therapy - Research output
- Lund University
Frequent and recent retrotransposition of orthologous genes plays a role in the evolution of sperm glycolytic enzymes | BMC...
Within each gene family, a single orthologous gene was typically retrotransposed frequently and independently in both species. ... Several isozymes in this pathway are expressed only during spermatogenesis, and gene targeting studies indicate that they are ... We found evidence for the alternative splicing of parent genes. Many retroposed sequences have maintained ORFs, suggesting a ... Dupressoir A, Heidmann T: Germ line-specific expression of intracisternal A-particle retrotransposons in transgenic mice. Mol ...
Pesquisa | Portal Regional da BVS
... a murine intracisternal A-particle derived RNA transport element; (iii) a tissue plasminogen activator protein signal leader ... Produtos do Gene gag do Vírus da Imunodeficiência Humana/genética , Produtos do Gene gag do Vírus da Imunodeficiência Humana/ ... Produtos do Gene gag do Vírus da Imunodeficiência Humana/genética , Produtos do Gene gag do Vírus da Imunodeficiência Humana/ ... Produtos do Gene env do Vírus da Imunodeficiência Humana/genética , Produtos do Gene env do Vírus da Imunodeficiência Humana/ ...
Env-less endogenous retroviruses are genomic superspreaders. - Immunology
... the intracisternal A-type particles (IAPs), and performing simple correlations across all ERV lineages, we show that when ERVs ... lose the env gene their proliferation within that genome is boosted by a factor of ∼30. We also show that ERV abundance follows ... Some ERV lineages proliferate by infecting germline cells, as do typical retroviruses, whereas others lack the env gene ... Animals, Endogenous Retroviruses, Genes, Intracisternal A-Particle, Genes, env, Genome, Humans, Mammals, Mutagenesis, ...
Mapping the m1A, m5C, m6A and m7G methylation atlas in zebrafish brain under hypoxic conditions by MeRIP-seq | BMC Genomics |...
... the overall level of each of these four modifications on the related genes was also progressively increased. Further ... with the increase of the gene expression levels, ... of these mutations are affected by intracisternal A-particles ( ... C Venn diagram shows the intersection of differential m1A modifier genes and AS genes in zebrafish brain tissue. D AS genes ... Table 1 Detailed information of m1A, m5C, m6A and m7G genes with 1, 2, 3, 4, or 5+ peaks per gene in the zebrafish brain under ...
Retrotransposon-Induced Heterochromatin Spread... | proLékárníky.cz
In mouse, IAPs (Intracisternal A-type Particle elements), long terminal repeats (LTR) retrotransposons (also termed endogenous ... We found only one gene that matched these criteria. It is important to note, however, that IAPs near the TSS of genes are rare ... DupressoirAHeidmannT 1996 Germ line-specific expression of intracisternal A-particle retrotransposons in transgenic mice. Mol ... Finally, such spreading into genes appears to be rare, since the transcriptional start sites of very few genes are less than ...
Developmental cannabidiol exposure increases anxiety and modifies genome-wide brain DNA methylation in adult female mice |...
The epigenome, particularly DNA methylation, is responsive to environmental input and can direct persistent patterns of gene ... The upstream region of the Agouti gene of Avy/a mice contains an intracisternal A particle (IAP) retrotransposon insertion that ... while intracisternal A particle (IAP) retrotransposons were unaffected (Additional file 8). Multiple genes known to interact ... Gene Ontology, phenotype, and disease terms were analyzed for overrepresentation in the list of DML-containing genes for each ...
SETDB1 prevents TET2-dependent activation of IAP retroelements in naïve embryonic stem cells | Genome Biology | Full Text
... including at the highly mutagenic intracisternal A particles (IAPs). We find that in the absence of SETDB1, TET2 activates IAP ... Lee J, Haruna T, Ishimoto A, Honjo T. Intracisternal type A particle-mediated activation of the Notch4/int3 Gene in a mouse ... For shRNA-mediated gene knockdown, ESCs were infected with viral particles carrying pLKO.1 constructs harbouring gene-specific ... Formation of an active form of the interleukin-2/15 receptor b-chain by insertion of the intracisternal A particle in a ...
category/vaccines | Custom Bio-Synthesis Blog
... the intracisternal A-type particles (IAPs), and performing simple correlations across all ERV lineages, the researchers could ... Gene (promoter). Functional role. HERV-E. Mid1. Opitz syndrome. HERV-E. Apolipoprotein C1. Liver and other tissues. HERV-E. ... Gene. Functional role. LINE-1. Factor VIII. Hemophilia A. LINE-1. Dystrophin. Muscular dystrophy. SINE. Fukutin. Muscular ... This piece of DNA can now code for the parts needed to make the virus particles including the proteins needed for the assembly ...
MESH TREE NUMBER CHANGES - 2014 MeSH. July 29, 2013
G5.360.340.358.840.500.345 Genes, Intracisternal A-Particle G5.360.340.24.340.490.360 G5.360.340.24.340.364.875.360 G5.360. ... G5.360.340.358.207.249 Genes, env G5.360.340.24.340.490.172 G5.360.340.24.340.364.875.172 G5.360.340.400.500.172 G5.360.340.358 ... G5.360.340.358.365.500 Genes, gag G5.360.340.24.340.490.258 G5.360.340.24.340.364.875.258 G5.360.340.400.500.258 G5.360.340.358 ... G5.360.340.397.500 Genes, pX G5.360.340.24.340.490.735 G5.360.340.24.340.364.875.735 G5.360.340.400.500.735 G5.360.340.358. ...
MESH TREE NUMBER CHANGES - 2014 MeSH. July 29, 2013
G5.360.340.358.840.500.345 Genes, Intracisternal A-Particle G5.360.340.24.340.490.360 G5.360.340.24.340.364.875.360 G5.360. ... G5.360.340.358.207.249 Genes, env G5.360.340.24.340.490.172 G5.360.340.24.340.364.875.172 G5.360.340.400.500.172 G5.360.340.358 ... G5.360.340.358.365.500 Genes, gag G5.360.340.24.340.490.258 G5.360.340.24.340.364.875.258 G5.360.340.400.500.258 G5.360.340.358 ... G5.360.340.397.500 Genes, pX G5.360.340.24.340.490.735 G5.360.340.24.340.364.875.735 G5.360.340.400.500.735 G5.360.340.358. ...
MESH TREE NUMBER CHANGES - 2014 MeSH. July 29, 2013
G5.360.340.358.840.500.345 Genes, Intracisternal A-Particle G5.360.340.24.340.490.360 G5.360.340.24.340.364.875.360 G5.360. ... G5.360.340.358.207.249 Genes, env G5.360.340.24.340.490.172 G5.360.340.24.340.364.875.172 G5.360.340.400.500.172 G5.360.340.358 ... G5.360.340.358.365.500 Genes, gag G5.360.340.24.340.490.258 G5.360.340.24.340.364.875.258 G5.360.340.400.500.258 G5.360.340.358 ... G5.360.340.397.500 Genes, pX G5.360.340.24.340.490.735 G5.360.340.24.340.364.875.735 G5.360.340.400.500.735 G5.360.340.358. ...
MESH TREE NUMBER CHANGES - 2014 MeSH. July 29, 2013
G5.360.340.358.840.500.345 Genes, Intracisternal A-Particle G5.360.340.24.340.490.360 G5.360.340.24.340.364.875.360 G5.360. ... G5.360.340.358.207.249 Genes, env G5.360.340.24.340.490.172 G5.360.340.24.340.364.875.172 G5.360.340.400.500.172 G5.360.340.358 ... G5.360.340.358.365.500 Genes, gag G5.360.340.24.340.490.258 G5.360.340.24.340.364.875.258 G5.360.340.400.500.258 G5.360.340.358 ... G5.360.340.397.500 Genes, pX G5.360.340.24.340.490.735 G5.360.340.24.340.364.875.735 G5.360.340.400.500.735 G5.360.340.358. ...
MESH TREE NUMBER CHANGES - 2014 MeSH. July 29, 2013
G5.360.340.358.840.500.345 Genes, Intracisternal A-Particle G5.360.340.24.340.490.360 G5.360.340.24.340.364.875.360 G5.360. ... G5.360.340.358.207.249 Genes, env G5.360.340.24.340.490.172 G5.360.340.24.340.364.875.172 G5.360.340.400.500.172 G5.360.340.358 ... G5.360.340.358.365.500 Genes, gag G5.360.340.24.340.490.258 G5.360.340.24.340.364.875.258 G5.360.340.400.500.258 G5.360.340.358 ... G5.360.340.397.500 Genes, pX G5.360.340.24.340.490.735 G5.360.340.24.340.364.875.735 G5.360.340.400.500.735 G5.360.340.358. ...
MESH TREE NUMBER CHANGES - 2014 MeSH. July 29, 2013
G5.360.340.358.840.500.345 Genes, Intracisternal A-Particle G5.360.340.24.340.490.360 G5.360.340.24.340.364.875.360 G5.360. ... G5.360.340.358.207.249 Genes, env G5.360.340.24.340.490.172 G5.360.340.24.340.364.875.172 G5.360.340.400.500.172 G5.360.340.358 ... G5.360.340.358.365.500 Genes, gag G5.360.340.24.340.490.258 G5.360.340.24.340.364.875.258 G5.360.340.400.500.258 G5.360.340.358 ... G5.360.340.397.500 Genes, pX G5.360.340.24.340.490.735 G5.360.340.24.340.364.875.735 G5.360.340.400.500.735 G5.360.340.358. ...
MESH TREE NUMBER CHANGES - 2014 MeSH. July 29, 2013
G5.360.340.358.840.500.345 Genes, Intracisternal A-Particle G5.360.340.24.340.490.360 G5.360.340.24.340.364.875.360 G5.360. ... G5.360.340.358.207.249 Genes, env G5.360.340.24.340.490.172 G5.360.340.24.340.364.875.172 G5.360.340.400.500.172 G5.360.340.358 ... G5.360.340.358.365.500 Genes, gag G5.360.340.24.340.490.258 G5.360.340.24.340.364.875.258 G5.360.340.400.500.258 G5.360.340.358 ... G5.360.340.397.500 Genes, pX G5.360.340.24.340.490.735 G5.360.340.24.340.364.875.735 G5.360.340.400.500.735 G5.360.340.358. ...
MeSH Browser
Genes, Immediate-Early [G05.360.340.024.340.364.875.345] * Genes, Intracisternal A-Particle [G05.360.340.024.340.364.875.360] ... Genes, R Genes, rap vpr Gene vpr Genes Previous Indexing. Genes, Viral (1989-1990). Public MeSH Note. 93; was GENES, RAP 1991- ... use GENES, VPR to search GENES, RAP 1991-92. History Note. 93; was GENES, RAP 1991-92; GENES, VPR was see GENES, RAP 1991-92. ... Genes [G05.360.340.024.340] * Genes, Microbial [G05.360.340.024.340.364] * Genes, Viral [G05.360.340.024.340.364.875] * Genes, ...
English
The "Intracisternal A Particles" (IAP) are retrotransposons whose life cycle is strikingly similar to retroviruses such as the ... "If a transposon or virus jumps into the middle of a gene, it could alter its function. And if transposons were allowed to ... The virus-like sequences are transposons, also known as "jumping genes". They have the ability to spontaneously replicate and ... Colossal will assist the rescue mission by leveraging genome sequencing and gene editing methods to save the endangered species ...
MeSH Browser
Genes, Immediate-Early [G05.360.340.024.340.364.875.345] * Genes, Intracisternal A-Particle [G05.360.340.024.340.364.875.360] ... Genes [G05.360.340.024.340] * Genes, Microbial [G05.360.340.024.340.364] * Genes, Viral [G05.360.340.024.340.364.875] * Genes, ... The vpu genes are not present in HIV-2 or SIMIAN IMMUNODEFICIENCY VIRUS.. Entry Term(s). vpu Genes Previous Indexing. Genes, ... Genes, Microbial [G05.360.340.358.024] * Genes, Viral [G05.360.340.358.024.875] * Genes, env [G05.360.340.358.024.875.172] ...
Items where Community is "Krainer lab" - CSHL Scientific Digital Repository
Basu, A., Dong, B., Krainer, A. R., Howe, C. C. (February 1997) The intracisternal A-particle proximal enhancer-binding protein ... Karni, R., de Stanchina, E., Lowe, S. W., Sinha, R., Mu, D., Krainer, A. R. (March 2007) The gene encoding the splicing factor ... Squires, C., Krainer, A., Barry, G., Shen, W. F., Squires, C. L. (December 1981) Nucleotide sequence at the end of the gene for ... Rigo, F., Hua, Y. M., Chun, S. J., Krainer, A. R., Bennett, C. F. (October 2011) Modulation of Gene Expression By ...
DeCS 2017 - July 04, 2017 version
DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells | Cell Research
... and the functional significance of these genes for germ cell development in vivo. Our work offers a comprehensive and high- ... indicating the existence of a delicate regulatory balance between pluripotency-related genes and germ cell-specific genes in ... and intracisternal A particles (IAPs) are more likely to be open in mouse PGCs than in somatic cells and epiblast ( ... A, B) Heatmaps showing tissue-specific proximal NDRs and the associated genes in human (A) and mouse (B) samples. (C, D) Gene ...