TRPS1 targeting by miR-221/222 promotes the epithelial-to-mesenchymal transition in breast cancer
... as basal-like subtype-specific miRNAs and showed that expression of miR-221/222 decreased expression of epitheli … ... Gene Expression Regulation, Neoplastic* * Homeodomain Proteins / genetics * Homeodomain Proteins / metabolism * Humans * MAP ... miRNAs and showed that expression of miR-221/222 decreased expression of epithelial-specific genes and increased expression of ... expression. We conclude that by promoting EMT, miR-221/222 may contribute to the more aggressive clinical behavior of basal- ...
Toll-like receptor 3 expressing tumor parenchyma and infiltrating natural killer cells in hepatocellular carcinoma patients
Gene Expression Regulation, Neoplastic * Humans * Immunohistochemistry * Kaplan-Meier Estimate * Killer Cells, Natural / ... Also, expression of chemokines or treatment with poly(I:C) decreased tumor growth. TLR3 expression in patient samples ... TLR3 expression was also associated with longer survival in HCC patients (hazard ratio of survival = 2.1, 95% confidence ... The relationship between TLR3 expression and survival was determined by the Kaplan-Meier univariate survival analysis and a log ...
LATS1 | Cancer Genetics Web
Neoplastic Cell Transformation. *Cancer Gene Expression Regulation. *Stomach Cancer. *Carcinogenesis. *Phosphorylation. *Soft ... Search the gene expression profiles from curated DataSets in the Gene Expression Omnibus (GEO) repository. ... Identification of gene expression models for laryngeal squamous cell carcinoma using co-expression network analysis.. Medicine ... In this study, a total of 116 differentially expressed genes (DEGs), including 11 upregulated genes and 105 downregulated genes ...
Biblio | Page 2 | Linus Pauling Institute | Oregon State University
Biblio | Page 9 | Linus Pauling Institute | Oregon State University
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes | Lund University Publications
DNA Breaks, Databases, Genetic, Gene Expression Regulation, Neoplastic, Genome, Human/genetics, Genome-Wide Association Study, ... Gene Expression Regulation, Neoplastic; Genome, Human/genetics; Genome-Wide Association Study; Humans; INDEL Mutation; Mutation ... We show that although point mutations and structural variants that drive cancer are less frequent in non-coding genes and ... We show that although point mutations and structural variants that drive cancer are less frequent in non-coding genes and ...
Publication Detail
Gene Expression Regulation, Neoplastic; Humans; Kelch-Like ECH-Associated Protein 1/metabolism*; Lipid Peroxides/metabolism; NF ... The overexpression of AKR genes as components of the smoking gene battery raises the issue as to whether this is part of a ... Human AKR genes also regulate retinoid, prostaglandin, and steroid hormone metabolism and can regulate the local concentrations ... Among all the human genes regulated by the Keap1/Nrf2 pathway, they are consistently the most overexpressed in response to Nrf2 ...
THRSP - Wikipedia
Ota Y, Mariash A, Wagner JL, Mariash CN (1997). "Cloning, expression and regulation of the human S14 gene". Mol. Cell. ... a metabolic integrator in normal and neoplastic cells". Thyroid. 8 (9): 815-25. doi:10.1089/thy.1998.8.815. PMID 9777755. ... The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and ... "Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention ...
Abhinav Adhikari, Ph.D. | Harvard Catalyst Profiles | Harvard Catalyst
Gene Expression Regulation, Neoplastic. 1. 2020. 8452. 0.060. Why? Apoptosis. 1. 2020. 9756. 0.060. Why? ...
The cancer stem cell subtype determines immune infiltration of glioblastoma - University of Regensburg Publication Server
GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesis - University of Regensburg Publication...
Gene Expression Regulation, Neoplastic. MESH. Glucose Transporter Type 1/genetics. MESH. Humans. MESH. ... Therefore, we aimed to analyze the expression and function of the GLUT1 gene in cases of HCC. We found significantly higher ... Therefore, we aimed to analyze the expression and function of the GLUT1 gene in cases .... ... However, its expression level and functional significance in hepatocellular cancer (HCC) are still disputed. ...
RALGDS | Cancer Genetics Web
Neoplastic Cell Transformation. *Cancer Gene Expression Regulation. *Cervical Cancer. *Cell Proliferation. *Neoplasm ... Search the gene expression profiles from curated DataSets in the Gene Expression Omnibus (GEO) repository. ... Ral GDS pathways highlighted the importance of the RalGDS pathways in the regulation of S100A10 gene expression. Depletion of ... Oncogenic RAS expression increased S100A10 gene expression which resulted in an increase in S100A10 protein levels. Analysis ...
XAF1 promotes neuroblastoma tumor suppression and is required for KIF1B?-mediated apoptosis | ScholarBank@NUS
Gene Expression Regulation, Neoplastic. Heterografts. Humans. Intracellular Signaling Peptides and Proteins. Kaplan-Meier ... gene expression regulation. Kaplan Meier method. metabolism. mortality. neuroblastoma. pathology. physiology. prognosis. tumor ... gene silencing. general aspects of disease. genetic transfection. human. human cell. human tissue. in vitro study. in vivo ... protein expression. protein function. survival rate. survival time. tumor growth. tumor volume. animal. apoptosis. ...
The roles of MASPIN expression and subcellular localization in non-small cell lung cancer.
Gene Regulatory Networks. *Gene Expression Regulation, Neoplastic. *Female. *Disease-Free Survival. Citation. APA ... Bioinformatics analysis also revealed the 85 most frequently altered neighboring genes of SERPINB5, and gene ontology (GO) and ... Wang X-F, Liang B, Zeng D-X, Lei W, Chen C, Chen Y-B, Huang J-A, Gu N, Zhu Y-H. The roles of MASPIN expression and subcellular ... Wang, X.-F., Liang, B., Zeng, D.-X., Lei, W., Chen, C., Chen, Y.-B., … Zhu, Y.-H. (2020). The roles of MASPIN expression and ...
Expression of multiple chemokine genes by a human mast cell leukemia.
"Expression of multiple chemokine genes by a human mast cell leukemia." J Biol Chem, vol. 269, no. 19, May 1994, pp. 13893-98. ... "Expression of multiple chemokine genes by a human mast cell leukemia." J Biol Chem 269, no. 19 (May 13, 1994): 13893-98. ... Expression of multiple chemokine genes by a human mast cell leukemia.. Publication , Journal Article ... Expression of multiple chemokine genes by a human mast cell leukemia. J Biol Chem. 1994 May 13;269(19):13893-8. ...
100 results in SearchWorks articles
gene expression regulation, neoplastic2. *genetic variation2. *growth hormone-secreting pituitary adenoma2 ... SPEN also emerges as a relevant gene for del1p36 syndrome by co-expression analyses. Finally, we show that haploinsufficiency ... Next-generation sequencing revealed they contained a fusidic acid resistance gene, exfoliative toxin genes and an epidermal ... were positive for the bla VIM gene using PCR. Sequencing was performed on 112 CIM-positive and 56 CIM-negative isolates (n = ...
Medical Science Monitor | Tenacigenin B Has Anti-Tumor Effect in Lymphoma by In Vitro and In Vivo Study - Article abstract ...
... relative protein expressions were evaluated by immunohistochemistry assay, and relative mRNA expression was evaluated by RT-PCR ... Tenacigenin B had anti-tumor effects on lymphoma via regulation of Aurora-A in vitro and in vivo. ... and relative protein expressions were measured by western blot assay in an in vitro study. In an in vivo study, we used a nude ... and P21 mRNA and protein expressions of the Drug group, the si-Aurora-A group, and the si-Aurora-A+Drug group were ...
Folate Deficiency: Practice Essentials, Background, Pathophysiology
... and impairment of methylation reactions involved in the regulation of gene expression, thus increasing neoplastic risks. ... Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene. Am J Clin Nutr. ... researchers have demonstrated that increasing folic acid levels led to dose-dependent down-regulation of tumor suppressor genes ... 40] and DNA strand breaks and hypomethylation within the P53 gene. [41] ...
Medical Science Monitor | MiR-506 Over-Expression Inhibits Proliferation and Metastasis of Breast Cancer Cells - Article...
miR-506 over-expression may thus be able to improve the malignant phenotype of breast cancer cells. ... CONCLUSIONS:MiR-506 over-expression significantly inhibits the proliferation, colony formation, and migration of breast cancer ... Gene Expression Regulation, Neoplastic - genetics, In Vitro Techniques, Lipids, Molecular Mimicry - genetics, Neoplasm ... MiR-506 Over-Expression Inhibits Proliferation and Metastasis of Breast Cancer Cells Fei YuACE, Mingli LvBCD, Dan LiBCD, ...
POZ for effect - POZ-ZF transcription factors in cancer and development - McMaster Experts
Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study<...
keywords = "Aged, Aged 80 and over, Castration, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, ... Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study. ... Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study. ... Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer : a prospective, two-stage study. ...
Poor prognosis of constitutive γ-H2AX expressing triple-negative breast cancers is associated with telomere length<...
keywords = "BRCA1 Protein/genetics, Cell Line, Tumor, Gene Expression Regulation, Neoplastic, Histones/metabolism, Humans, ... Further, we correlated γ-H2AX expression in breast cancer tumor tissues with telomere length.RESULTS: γ-H2AX positive breast ... Further, we correlated γ-H2AX expression in breast cancer tumor tissues with telomere length.RESULTS: γ-H2AX positive breast ... Further, we correlated γ-H2AX expression in breast cancer tumor tissues with telomere length.RESULTS: γ-H2AX positive breast ...
Abnormal GRHL2 Methylation Confers Malignant Progression to Acute Leukemia
i,Results,/i,. We found a lower level of GRHL2 expression not only in acute leukemia patients but also in cell lines when ... At the same time, the expression level of GRHL2 in patients with acute leukemia was significantly correlated with leukocyte ... Then we investigated the demethylating effect of arsenic trioxide and 5-azacitidine on the mRNA and protein expression levels ... In addition, the lower GRHL2 expression group showed a significantly lower overall survival rate in acute leukemia patients ...
Transcriptional deregulation of myc in IgH/myc 6;7 translocation carrying rat immunocytomas | Make a difference for cancer
Gene Expression Regulation, Neoplastic * Genes, Immunoglobulin * Genes, myc * Humans * Immunoglobulin Heavy Chains ... Run-on analysis showed transcriptional attenuation in the normal rat myc gene, similar to the situation in mice and humans. The ... of the intact gene, proximal to the myc promoters. In this paper we describe the effect of the translocation on myc ...
Multiple myeloma. Medical search
Gene Expression Regulation, Neoplastic. Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence ... GeneticGene Expression Regulation, NeoplasticChromosomes, Human, Pair 13Cell ProliferationCell SurvivalChromosomes, Human, Pair ... GeneticDoxorubicinGene Expression Regulation, NeoplasticCombined Modality TherapyRecurrenceSurvival AnalysisSurvival Rate ... Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR ...
Dong-Young Ryu - Citation Index - NCSU Libraries
Gene Expression Regulation, Neoplastic; Hepcidins; Immunoblotting; Injections, Subcutaneous; Iron / blood; Iron / metabolism; ... Gene Expression Regulation, Enzymologic; Isoenzymes / metabolism; Liver / drug effects; Liver / enzymology; Male; Mice; Mice, ... Gene Expression Regulation, Enzymologic; Immunohistochemistry; Isoenzymes / genetics; Liver / enzymology; Male; Mice; Mice, ... Regulation of iron metabolism-related genes in diethylnitrosamine-induced mouse liver tumors ...
ΔNp63-mediated regulation of hyaluronic acid metabolism and signaling supports HNSCC tumorigenesis
Gene Expression Regulation, Neoplastic; HEK293 Cells; Head and Neck Neoplasms; Humans; Hyaluronan Receptors; Hyaluronan ... Importantly, p63 expression is positively correlated with CD44, HAS3, and ABCC1 expression in squamous cell carcinoma datasets ... Importantly, p63 expression is positively correlated with CD44, HAS3, and ABCC1 expression in squamous cell carcinoma datasets ... activation and the expression of ABCC1 multidrug transporter gene, thus contributing to tumor cell proliferation and ...
Differential expression of cancer-associated proteins in breastmilk. - Texas A&M University (TAMU) Scholar
Differential expression of cancer-associated proteins in breastmilk. - Texas A&M University (TAMU) Scholar profile, educations ... Gene Expression Regulation, Neoplastic * Humans * Infant, Newborn * Kallikreins * Lactation * Lipocalin-2 * Lipocalins ... To better understand the patterns of cancer-related protein expression in the breasts of lactating women, we determined the ... Sixteen proteins whose expression is altered in breast cancer (11 kallikreins [KLKs], basic fibroblast growth factor [bFGF], ...
A prognostic DNA methylation signature for stage I non-small-cell lung cancer<...
Gene Expression Regulation, Neoplastic, Humans, Kaplan-Meier Estimate, Lung Neoplasms/genetics, Male, Middle Aged, Neoplasm ... the validation cohort of the significant methylated sites from the discovery cohort found that hypermethylation of five genes ... the validation cohort of the significant methylated sites from the discovery cohort found that hypermethylation of five genes ... the validation cohort of the significant methylated sites from the discovery cohort found that hypermethylation of five genes ...