Loading...
*  In vivo expression profile of an endothelial nitric oxide synthase promoter-reporter transgene.
... gene. Although a more comprehensive understanding of transcriptional regulation of eNOS is emerging with respec ... is primarily attributable to constitutive expression of the endothelial nitric oxide synthase (eNOS) ... Gene Expression Regulation, Enzymologic*. Genes, Reporter. Hypertension / enzymology. Juxtaglomerular Apparatus / enzymology. ... 16603213 - Up-regulation of cytosolic phospholipase a2alpha expression by n,n-diethyldithiocarbama.... 11466573 - Molecular ...
  http://www.biomedsearch.com/nih/In-vivo-expression-profile-endothelial/10749733.html
*  Availability of Rubisco small subunit up-regulates the transcript levels of large subunit for stoichiometric assembly of its...
For synthesis of the Rubisco holoenzyme, both genes need to be expressed coordinately. To ... of eight small subunits coded for by the nuclear RBCS multigene family and eight large subunits coded for by the rbcL gene in ... Gene Expression Regulation, Enzymologic. Gene Expression Regulation, Plant*. Genes, Plant*. Holoenzymes / genetics, metabolism* ... These results demonstrate that the availability of RBCS protein up-regulates the gene expression of rbcL primarily at the ...
  http://www.biomedsearch.com/nih/Availability-Rubisco-Small-Subunit-Up/22811433.html
*  Differential expression of two flavonoid 3'-hydroxylase cDNAs involved in biosynthesis of anthocyanin pigments and 3...
Gene Expression Regulation, Enzymologic*. Gene Expression Regulation, Plant*. Genes, Plant. Mixed Function Oxygenases / ... The sorghum mesocotyls represent a good system for investigation of differential regulation of F3'H genes/alleles responding to ... In sorghum mesocotyls, SbF3'H1 expression was involved in light-specific anthocyanin accumulation while SbF3'H2 expression was ... Differential expression of two flavonoid 3'-hydroxylase cDNAs involved in biosynthesis of anthocyanin pigments and 3- ...
  http://www.biomedsearch.com/nih/Differential-expression-two-flavonoid-3/16943219.html
*  The activity and expression of NTPDase is altered in lymphocytes of multiple sclerosis patients.
Gene Expression Regulation, Enzymologic*. Humans. Lymphocytes / metabolism*. Male. Middle Aged. Multiple Sclerosis / enzymology ... Next Document: The clinical implications of MMP-11 and CK-20 expression in human breast cancer.. ... We evaluated the activity and expression of NTPDase and adenosine deaminase (ADA) activity in lymphocytes from patients with ... RESULTS: The NTPDase activity and expression were increased in lymphocytes from RRMS patients when compared with the control ...
  http://www.biomedsearch.com/nih/activity-expression-NTPDase-altered-in/19914228.html
*  JNK1, JNK2, and JNK3 are involved in P-glycoprotein-mediated multidrug resistance of hepatocellular carcinoma cells.
Gene Expression Regulation, Enzymologic. Gene Expression Regulation, Neoplastic. Humans. Inhibitory Concentration 50. Liver ... JNK1, JNK2 and JNK3 mRNA expression levels were quantified by real-time PCR. Expression and phosphorylation of JNK1, JNK2, and ... Previous Document: Relationship between the expression of IP-10 and IP-10 mRNA in peripheral blood and HBV DNA level in.... ... Flow cytometry was used to analyze the cell cycle distribution and to measure the expression levels of P-glycoprotein (P-gp) ...
  http://www.biomedsearch.com/nih/JNK1-JNK2-JNK3-are-involved/20525557.html
*  eNOS mediates L-arginine-induced inhibition of thick ascending limb chloride flux.
Gene Expression Regulation, Enzymologic. Loop of Henle / enzymology*. Male. Mice. Mice, Inbred C57BL. Mice, Knockout. Nitric ... 7557128 - Role of inducible nitric oxide synthase expression and peroxynitrite formation in guine.... 16635558 - Inhibitory ...
  http://www.biomedsearch.com/nih/eNOS-mediates-L-arginine-induced/10642318.html
*  An inducible transgenic mouse model for familial hypertension with hyperkalaemia (Gordon's syndrome or pseudohypoaldosteronism...
Gene Expression Regulation, Enzymologic / drug effects. Genotype. Humans. In Situ Hybridization, Fluorescence. Kidney / ... This inducible model shows, for the first time, that in vivo expression of a mutant WNK4 protein is sufficient to cause the ... Withdrawal of doxycycline switched off mutant TG expression and the disappearance of the PHAII phenotype. Western blotting of ... copy numbers and displaying varying degrees of TG expression (low, medium and high). Each of these transgenic lines ...
  http://www.biomedsearch.com/nih/inducible-transgenic-mouse-model-Familial/23336180.html
*  The expression of a grapefruit gene encoding an isoflavone reductase-like protein is induced in response to UV irradiation.
Gene Expression Regulation, Enzymologic / radiation effects*. Gene Expression Regulation, Plant / radiation effects*. Immunity ... The expression of the IRL gene was demonstrated to be induced also by wounding and pathogen infection.. ... In order to gain insight into the mechanism of this UV-induced resistance we initiated a study for isolation of genes induced ... Sequence analysis revealed that this cDNA represents a gene encoding for an isoflavone reductase-like protein and was termed ...
  http://www.biomedsearch.com/nih/expression-grapefruit-gene-encoding-isoflavone/9520276.html
*  Hydrolytic pathway protects against ceramide-induced apoptosis in keratinocytes exposed to UVB.
Gene Expression Regulation, Enzymologic / radiation effects. Humans. Hydrolysis. Keratinocytes* / cytology, drug effects, ... 19017998 - Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine respo.... 19803548 - ...
  http://www.biomedsearch.com/nih/Hydrolytic-Pathway-Protects-against-Ceramide/20520628.html
*  mTOR/S6 kinase pathway contributes to astrocyte survival during ischemia. | CureHunter
Gene Expression Regulation, Enzymologic. *Glucose (metabolism) *Ischemia (pathology) *Mice. *Mice, Inbred C57BL ... To identify genes involved in astrocyte function during ischemia, we performed mRNA differential display in astrocytes after ... OGD-induced apoptosis was increased by the combined deletion of S6K1 and S6K2 genes, as well as by treatment with rapamycin ... Rescue of either S6K1 or S6K2 expression by adenoviral infection revealed that protective functions were specifically mediated ...
  http://www.curehunter.com/public/pubmed19535330.do
*  Kallikrein gene 'knock-down' by small interfering RNA transfection induces a profibrotic phenotype in rat mesangial cells.
The aim of the current investigation was to delineate the role of kallikrein in the regulation of fibrosis, by 'knocking dow ... Gene Expression Regulation, Enzymologic / drug effects, genetics. LDL-Receptor Related Protein 1 / drug effects, genetics, ... The aim of the current investigation was to delineate the role of kallikrein in the regulation of fibrosis, by 'knocking down' ... 8905915 - Regulation of constitutive rat hepatic cytochromes p450 by 3-methylcholanthrene.. 23082035 - Manuka honey is ...
  http://www.biomedsearch.com/nih/Kallikrein-gene-knock-down-by/18090545.html
*  Effects of 4d and 4e on three types of MAP kinases and | Open-i
Gene Expression Regulation, Enzymologic*. *MAP Kinase Signaling System*. *Microglia/metabolism*. *p38 Mitogen-Activated Protein ... We confirmed that 4d and 4e regulate the expression of iNOS, COX-2, IL-1β, and IL-6 at the mRNA level and the expression of TNF ... We confirmed that 4d and 4e regulate the expression of iNOS, COX-2, IL-1β, and IL-6 at the mRNA level and the expression of TNF ... which are key transcription factors for inflammatory gene expression in microglial cells (Figure 9B). To confirm an involvement ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3921125_pone.0087030.g009&req=4
*  Construct used for tobacco transformation and Western b | Open-i
Gene Expression Regulation, Enzymologic. *Gene Expression Regulation, Plant. *Hydrogen Peroxide/pharmacology. *Oxidative Stress ... Expression patterns of various stress responsive genes were enhanced, and the activities of anti-oxidative enzymes were ... Expression patterns of various stress responsive genes were enhanced, and the activities of anti-oxidative enzymes were ... Expression of AtIpk2β is driven by the Cauliflower Mosaic Virus 35S promoter. Ocs, ocs terminator; RB and LB, right and left ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2238787_11103_2007_9267_Fig2_HTML&req=4
*  Overexpression of activated PIK3CA in OSE resulted in h | Open-i
Gene Expression Regulation, Enzymologic*. *Gene Expression Regulation, Neoplastic*. *Genes, ras*. *Ovary/enzymology* ... We found that PIK3CA mRNA expression level was 18.5-fold higher in OSEs from PIK3CA-Tg mice (200.93 ±89.47 relative expression ... We found that PIK3CA mRNA expression level was 18.5-fold higher in OSEs from PIK3CA-Tg mice (200.93 ±89.47 relative expression ... We found that expression of the activated PIK3CA resulted in hyperplasia in mouse OSE and a paucity of follicles in four month- ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2629728_pone.0004295.g007&req=4
*  Recombinant P32 binds to recombinant RNase H1, enhances | Open-i
Gene Expression Regulation, Enzymologic. *HEK293 Cells. *HeLa Cells. *Humans. *Hydrolysis. *Mass Spectrometry ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3750045_pone.0071006.g002&req=4
*  Competitive effect of Zn(II) on metal ion accumulation. | Open-i
Gene Expression Regulation, Enzymologic/physiology*. *Manganese/metabolism*. *Oxidative Stress/physiology*. *Streptococcus ... Bottom Line: We show that manganese starvation led to a decrease in sodA transcription indicating that expression of sodA was ... Bottom Line: We show that manganese starvation led to a decrease in sodA transcription indicating that expression of sodA was ... We show that manganese starvation led to a decrease in sodA transcription indicating that expression of sodA was regulated ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3928430_pone.0089427.g002&req=4
*  HPGD | Cancer Genetics Web
Enzymologic Gene Expression Regulation. *Squamous Cell Carcinoma. *Genetic Variation. *Receptors, Prostaglandin E, EP2 Subtype ... Search the gene expression profiles from curated DataSets in the Gene Expression Omnibus (GEO) repository. ... was used to compare gene expression across groups. ER- case samples displayed significantly higher expression of 18 genes/ ... In parallel with suppressing 15-PGDH expression, H. pylori infection activated expression of TLR4 and MyD88 expression, ...
  http://www.cancerindex.org/geneweb/HPGD.htm
*  14-3-3 recruitment to chromatin is important for tr | Open-i
14-3-3 recruitment to chromatin is important for transcriptional elongation of GATA-4 and of fetal cardiac genes. (A) ChIP-qPCR ... Gene Expression Regulation, Enzymologic. *Humans. *Male. *Mice, Knockout. *Phosphorylation. *Protein Processing, Post- ... Bottom Line: Heart failure is associated with the reactivation of a fetal cardiac gene programme that has become a hallmark of ... Bottom Line: Heart failure is associated with the reactivation of a fetal cardiac gene programme that has become a hallmark of ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4383650_path0235-0606-f6&req=4
*  CAF induced proliferation and resistance to apoptosis, | Open-i
Gene Expression Regulation, Enzymologic/drug effects. *Granulocytes/immunology. *Humans. *Kidney Tubules/drug effects/ ... we found that CAF up-regulated in hypoxic HUVECs the expression of several genes involved in angiogenesis, cell proliferation ... we found that CAF up-regulated in hypoxic HUVECs the expression of several genes involved in angiogenesis, cell proliferation ... Results: CAF increased basal as well as acetylcholine-induced NO release by a mechanism independent from eNOS expression and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4390339_pone.0117530.g008&req=4
*  Effects of feeding diets enriched in 5-HTP and L-TRP on | Open-i
Gene Expression Regulation, Enzymologic*/drug effects. *Glucose Transport Proteins, Facilitative/genetics*/metabolism* ... Our results suggest that increasing 5-HT production during the transition from pregnancy to lactation increases mRNA expression ... Our results suggest that increasing 5-HT production during the transition from pregnancy to lactation increases mRNA expression ... Serotonin (5-HT) affects expression of liver metabolic enzymes and mammary gland glucose transporters during the transition ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3585179_pone.0057847.g002&req=4
*  Assessment of the mutual influence of toluene- and mena | Open-i
Gene Expression Regulation, Enzymologic*. *Protein Kinases/genetics*/metabolism. *Pseudomonas putida/enzymology*/genetics ... opposing effects of menadione on glucose and toluene metabolism may be partially responsible for the interwoven regulation of ... opposing effects of menadione on glucose and toluene metabolism may be partially responsible for the interwoven regulation of ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4321377_mbt20008-0103-f8&req=4
*  Regulation of the hetero-octameric ATP phosphoribosyl transferase complex from Thermotoga maritima by a tRNA synthetase-like...
Gene Expression Regulation, Bacterial. MESH. Gene Expression Regulation, Enzymologic. MESH. Histidine/metabolism. MESH. ... Regulation of the hetero-octameric ATP phosphoribosyl transferase complex from Thermotoga maritima by a tRNA synthetase-like ... Regulation of the hetero-octameric ATP phosphoribosyl transferase complex from Thermotoga maritima by a tRNA synthetase-like ...
  https://epub.uni-regensburg.de/13678/
*  Recruitment of RNA Polymerase II to the Nos2 Promoter b | Open-i
Gene Expression Regulation, Enzymologic. *Interferon Type I/metabolism. *Interferon-Stimulated Gene Factor 3/metabolism ... To determine which situation applies to the macrophage Nos2 gene, we analyzed pol II association by ChIP. As shown in Figure 5A ... To determine which situation applies to the macrophage Nos2 gene, we analyzed pol II association by ChIP. As shown in Figure 5A ... the enzyme is recruited in response to the stimulus of gene activation (Adelman et al., 2009). ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2914224_gr5&req=4
*  The CISK PX domain can specifically bind phosphoinositi | Open-i
Gene Expression Regulation, Enzymologic. *Immediate-Early Proteins. *Membrane Proteins/isolation & purification. *Molecular ... The expression of the GST fusion proteins is shown on the right. Mentions: To test this possibility, we investigated the ... Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides. ... Although regulation of Akt can be achieved through several mechanisms, including its phosphoinositide-binding Pleckstrin ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2196448_0105089f2&req=4
*  Arginase inhibition reduces increases in UAE in STZ-dia | Open-i
Gene Expression Regulation, Enzymologic/drug effects. *Histiocytes/drug effects/pathology. *Hyperglycemia/etiology ... Research design and methods: The impact of arginase activity and expression on renal damage was evaluated in spontaneously ... Research design and methods: The impact of arginase activity and expression on renal damage was evaluated in spontaneously ... Bottom Line: In contrast, arginase-1 expression was undetectable in kidneys under normal or diabetes conditions.The increase in ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3198072_3015fig4&req=4