The PBAP remodeling complex is required for histone H3.3 replacement at chromatin boundaries and for boundary functions |...
2007). General, negative feedback mechanism for regulation of Trithorax-like gene expression in vivo: new roles for GAGA factor ... Department of Developmental Genetics, National Institute of Genetics, Mishima, Shizuoka-ken 411-8540, Japan. ... 2003). Drosophila FACT contributes to Hox gene expression through physical and functional interactions with GAGA factor. Genes ... 2003). A novel boundary element may facilitate independent gene regulation in the Antennapedia complex of Drosophila. EMBO J. ...http://dev.biologists.org/content/139/24/4582
Long noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes | Genome Biology | Full Text
This expression is reduced at later developmental stages in all three species, suggesting that the locus has retained temporal ... Many such lncRNA loci may thus be involved in the cis-regulation of neighboring protein-coding transcription factor genes [17, ... As these lncRNAs do not differ substantially from protein-coding genes in their sequence or expression properties, we propose ... Bouchard M, Grote D, Craven SE, Sun Q, Steinlein P, Busslinger M: Identification of Pax2-regulated genes by expression ...https://genomebiology.biomedcentral.com/articles/10.1186/gb-2010-11-7-r72
Long non-coding RNA - Wikipedia
... may be illustrative of a generalised mechanism that tightly regulates important developmental genes with complex expression ... such as the heat shock genes. This additional hierarchy of regulation that exempts individual genes from the generalised ... July 2008). "Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta- ... A recent study observed an inverse expression profile of the p15 gene and an antisense ncRNA in leukaemia. A detailed analysis ...https://en.wikipedia.org/wiki/Long_non-coding_RNA
Long noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes. - Nuffield Department of...
... and investigate whether they exhibit conservation of brain expression. In contrast to conventional protein-coding genes, the ... and similarities in their pattern of brain expression during embryonic and early postnatal stages together indicate that these ... orthologs among birds and mammals within sequence and expression databases. RESULTS: Here, we performed a multi-disciplinary ... sequences, transcriptional start sites, exon structures, and lengths for these non-coding genes are all highly variable. ...https://www.ndcn.ox.ac.uk/publications/106551
Solexa Sequencing of Novel and Differentially Expressed MicroRNAs in Testicular and Ovarian Tissues in Holstein Cattle
... of the role of miRNA in reproductive biological processes and the mechanisms of target gene expression and regulation. ... Developmental Cell. 2006;11:441-50 10. Coutinho LL, Matukumalli LK, Sonstegard TS. et al. Discovery and profiling of bovine ... of all mammalian genes encode for miRNA, which regulate the expression of approximately 30% of all of the protein-coding genes ... Caraux G, Pinlonche S. PermutMatrix: a graphical environment to arrange gene expression profiles in optimal linear order. ...http://www.ijbs.com/v07p1016.htm
Browsing BioMedCentral SWORD Deposits by Subject "Gene Expression Regulation, Developmental"
... Archie Digital Collections. ... Browsing BioMedCentral SWORD Deposits by Subject "Gene Expression Regulation, Developmental". * 0-9 ...http://archie.kumc.edu/handle/2271/794/browse?value=Gene+Expression+Regulation%2C+Developmental&type=subject
Developmental Regulation of Gonadotropin-releasing Hormone Gene Expression by the MSX and DLX Homeodomain Protein Families
... *. ... Therefore, we propose that MSX and DLX family members participate in developmental regulation of GnRH gene expression. ... result in dynamic regulation of GnRH promoter expression. Indeed, the transcriptional activity of the GnRH gene appears to be ... in regulation of gene expression during development is well documented in vertebrate and invertebrate species (19-23). ...http://pubmedcentralcanada.ca/pmcc/articles/PMC2932481/
Genetic and epigenetic regulation of gene expression in fetal and adult human livers | BMC Genomics | Full Text
Our analyses generated a comprehensive resource of factors involved in the regulation of hepatic gene expression, and allowed ... and gene expression levels (526 unique genes (eQTL)), at a false discovery rate (FDR) < 0.05. Of the 526 unique eQTL associated ... we identified 657 differentially methylated genes with adult-specific expression, these genes were enriched for transcription ... However, there is substantial inter-individual variation in hepatic gene expression, and although numerous genetic factors have ...https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-15-860
Patent US7356416 - Method and system for automated inference creation of physico-chemical ... - Google Patents
Gene Expression Regulation, Developmental/drug effects. MH -. Mesoderm/drug effects/*physiology. MH -. Microinjections. ... given a gene expression profile indicating that expression of Gene X is inhibited in cells treated with Compound Y, this datum ... Gene expression and evaluation system. WO2000015847A2. Sep 8, 1999. Mar 23, 2000. Gene Logic, Inc.. Genomic knowledge discovery ... with the genes said gene expression profile reveals to be up-regulated or down-regulated under pre-determined experimental ...http://www.google.com/patents/US7356416?dq=KOI-18
DNA Methylation Research Trends
Developmental Gene Expression Regulation. 08.. Lecture Notes on Computational Mutation. 09.. Fragile Sites: New Discoveries and ...https://www.novapublishers.com/catalog/product_info.php?products_id=5718
Handbook on Longevity: Genetics, Diet and Disease
Developmental Gene Expression Regulation. 08.. Lecture Notes on Computational Mutation. 09.. Fragile Sites: New Discoveries and ... Research on Aging and Longevity in the Parthenogenetic Marbled Crayfish, with Special Emphasis on Stochastic Developmental ...https://www.novapublishers.com/catalog/product_info.php?products_id=9477
High oxygen prevents fetal lethality due to lack of catecholamines.
Gene Expression Regulation, Developmental. Heart Rate. Hypoxia-Inducible Factor 1 / genetics, metabolism. Male. Mice. Mice, ... Previous Document: In vivo regulation of endothelium-dependent vasodilation in the rat renal circulation and the effect.... ... GSE10341), hypoxia-inducible factor-1 target genes are induced to a greater extent in null fetuses than in wt siblings, ...http://www.biomedsearch.com/nih/High-oxygen-prevents-fetal-lethality/18635452.html
beta-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium.
Gene Expression Regulation, Developmental. Gene Knockout Techniques. Integrases / genetics. Lac Operon. Mice. Mice, Inbred ... have used transgenic and cell type-specific knockout strategies to determine roles for beta-catenin-regulated gene expression ... Functional knockout of beta-catenin had no impact on expression of Clara cell differentiation markers, mitotic index, or ...http://www.biomedsearch.com/nih/beta-Catenin-Not-Necessary-Maintenance/19213872.html
Restricting Bmp-4 mediated apoptosis in hindbrain neural crest.
Gene Expression Regulation, Developmental. In Situ Hybridization. Neural Crest / cytology*, drug effects, metabolism*. Proteins ... An interesting feature of these domains of Noggin expression is that they lie between territories of Bmp-4 expression, ... Title: Developmental dynamics : an official publication of the American Association of Anatomists Volume: 220 ISSN: 1058-8388 ... At these later stages, expression also becomes apparent in the migratory post-otic crest as it flows by the otic vesicle. ...http://www.biomedsearch.com/nih/Restricting-Bmp-4-mediated-apoptosis/11241835.html
Caffeine acts via A1 adenosine receptors to disrupt embryonic cardiac function.
Gene Expression Regulation, Developmental*. Heart / embryology*. Heart Rate / drug effects. Mice. Mice, Inbred C57BL. Mice, ... Real-time PCR analysis of RNA from isolated E9.5 and E12.5 hearts showed that A1AR and A2aAR genes were expressed at both ages ... Section of Developmental Endocrinology and Biology, Yale Child Health Research Center, Department of Pediatrics, Yale ... At E12.5, embryonic hearts lacking A1AR expression (A1AR-/-) had elevated heart rates compared to A1AR+/- littermates, A1AR-/- ...http://www.biomedsearch.com/nih/Caffeine-Acts-via-A1-Adenosine/22164264.html
In vivo studies on nonmuscle myosin II expression and function in heart development.
Gene Expression Regulation, Developmental. Mice. Models, Molecular. Myocardium / metabolism. Nonmuscle Myosin Type IIB / ... in mouse hearts deficient in NM II-B expression results in destabilization of N-cadherin and beta-catenin in the intercalated ...http://www.biomedsearch.com/nih/In-vivo-studies-nonmuscle-myosin/22201759.html
Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes...
Gene Expression Regulation, Developmental. Mice. Mice, Knockout. Microarray Analysis. Nerve Tissue Proteins / genetics, ...http://www.biomedsearch.com/nih/Asymmetric-Segregation-Double-Stranded-RNA/22902295.html
The miR-30 family microRNAs confer epithelial phenotype to human pancreatic cells.
Gene Expression Profiling. Gene Expression Regulation, Developmental. Humans. Mesenchymal Stromal Cells / metabolism, ... Previous Document: Downregulation of ZnT8 expression in pancreatic ?-cells of diabetic mice.. Next Document: Physiological ... We found that miR-30 family microRNAs target mesenchymal gene transcripts and maintain them in a translationally inactive state ...http://www.biomedsearch.com/nih/miR-30-family-microRNAs-confer/21099261.html
Pitx2 regulates gonad morphogenesis.
Gene Expression Regulation, Developmental / physiology. Germ Cells / cytology, physiology*. Homeodomain Proteins. Male. Mitotic ... by modulating cyclinD1 expression during asymmetric ovarian development, Pitx2 appears to control gonad organ size. All ... it is not yet clearly understood how specific gene functions are linked to the specific morphogenetic processes underlying the ... of paired organs along the left-right body axis has been shown to be regulated by the activity of the homeobox containing gene ...http://www.biomedsearch.com/nih/Pitx2-regulates-gonad-morphogenesis/18678914.html
Eya1 is required for lineage-specific differentiation, but not for cell survival in the zebrafish adenohypophysis.
Gene Expression Regulation, Developmental / physiology. Growth Hormone / biosynthesis, genetics. Homeodomain Proteins / ... Furthermore, eya1 is required for maintenance of pit1 expression, leading to subsequent loss of cognate hormone gene expression ... Title: Developmental biology Volume: 292 ISSN: 0012-1606 ISO Abbreviation: Dev. Biol. Publication Date: 2006 Apr ... in thyrotropes and somatotropes of mutant embryos, whereas prolactin expression in lactotropes persists. In contrast to other ...http://www.biomedsearch.com/nih/Eya1-required-lineage-specific-differentiation/16458879.html
Dissecting teleost B cell differentiation using transcription factors.
B cell developmental pathways in teleost fishes are poorly understood. In the absence of serological reagents, an alternative ... Gene Expression Regulation, Developmental / immunology. Lymphocyte Activation / genetics. Transcription Factors / immunology*. ... Possible future studies in teleost B cell development are suggested in the context of gene regulation. Lastly, broader impacts ... Title: Developmental and comparative immunology Volume: 35 ISSN: 1879-0089 ISO Abbreviation: Dev. Comp. Immunol. Publication ...http://www.biomedsearch.com/nih/Dissecting-teleost-B-cell-differentiation/21251922.html
Genome-wide gene expression analysis supports a developmental model of low temperature tolerance gene regulation in wheat ...
Analysis of variance of gene expression separated the samples by genetic background and by the developmental stage before or ... The levels of expression of these genes were highly influenced by the initial rate and the duration of the gene's response to ... The results support the developmental model of LT tolerance gene regulation and demonstrate the complex genotype by environment ... Using gene-specific ANOVA we identified 12,901 genes (at p < 0.001) that change in expression with respect to both genotype and ...https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-12-299
Nerve growth factor induces the expression of functional FSH receptors in newly formed follicles of the rat ovary.
Gene Expression Regulation, Developmental / drug effects. Nerve Growth Factor / pharmacology*. Organ Culture Techniques. ... This effect was cAMP-independent but additive to the cAMP-mediated increase in FSHR gene expression induced by either forskolin ... Previous Document: Localization and regulation of a functional GHRH receptor in the rat renal medulla.. Next Document: Caspase- ... 22542937 - Negative regulation of odd-skipped related 2 by tgf-beta achieves the induction of cell.... 24992387 - Anti-mirs ...http://www.biomedsearch.com/nih/Nerve-growth-factor-induces-expression/11897707.html
A factor(s) secreted from MIN-6 beta-cells stimulates differentiation of definitive endoderm enriched embryonic stem cells...
Gene Expression Regulation, Developmental / drug effects. Humans. Insulin-Secreting Cells / physiology, secretion*. ...http://www.biomedsearch.com/nih/factors-secreted-from-MIN-6/20674663.html
Green tea extract increases cyclophosphamide-induced teratogenesis by modulating the expression of cytochrome P-450 mRNA.
Gene Expression Regulation, Developmental / drug effects. Male. Microsomes, Liver / drug effects, enzymology. Plant Extracts / ... Moreover, repeated treatment with GTE greatly increased mRNA expression and activity of hepatic cytochrome P-450 (CYP) 2B, ... while reducing CYP3A expression (a detoxifying enzyme). The results suggest that repeated intake of GTE may aggravate ...http://www.biomedsearch.com/nih/Green-tea-extract-increases-cyclophosphamide/19103281.html