*  PLOS Genetics: A Comprehensive tRNA Deletion Library Unravels the Genetic Architecture of the tRNA Pool
When a deleted tRNA belongs to a family which contains multiple genes with the same anti-codon, the affected cells responded by ... Our tRNA deletion library is a unique resource that paves the way towards fully characterizing the tRNA pool and their role in ... Co-deletion of tRNA combinations revealed that tRNAs with essential function can be compensated by members of the same or ... We created a comprehensive tRNA deletion library in yeast and assessed the essentiality of each tRNA in multiple conditions. ...
  http://journals.plos.org/plosgenetics/article/figure?id=10.1371/journal.pgen.1004084.g004
*  久米 一規(大学院先端物質科学研究科)
Screening for a gene deletion mutant whose temperature sensitivity is suppressed by FK506 in budding yeast and its application ... Effect of ethanol on cell growth of budding yeast: Genes that are important for cell growth in the presence of ethanol, ... GENES TO CELLS, 20巻, 12号, pp.1046-pp.1058, DEC 2015. DOIを用いた論文検索結果へのリンク ...
  http://seeds.office.hiroshima-u.ac.jp/profile/ja.ea18e48d41ddec8c520e17560c007669.html
*  Strain sensitivity to different translation-inhibitory | Open-i
Wild type (WT) or gene deletion mutant strains (yploo9cΔ, yil137cΔ, ypl183w-aΔ, ydr056cCΔ and ... Wild type (WT) or gene deletion mutant strains (yploo9cΔ, yil137cΔ, ypl183w-aΔ, ydr056cCΔ and yjr111cΔ) were serially diluted ... Wild type (WT) or gene deletion mutant strains (yploo9cΔ, yil137cΔ, ypl183w-aΔ, ydr056cCΔ and yjr111cΔ) were serially diluted ... More than 70,000 strains were analyzed from the array of gene deletion mutant yeast strains. As expected, the overall profiles ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2925817_1472-6769-10-6-2&req=4
*  Gene Deletion Linked to Mental Illness, Obesity
Home » Disorders » Eating Disorders » Gene Deletion Linked to Mental Illness, Obesity. Gene Deletion Linked to Mental Illness, ... psychcentral.com/news/2012/10/11/gene-deletion-linked-to-mental-illness-obesity/45914.html ... "Because thousands of genes are involved in mood, anxiety, or obesity, it allows us to root our studies on a solid foundation." ... Linking a deletion in BDNF conclusively to mood and anxiety really tells us that it is possible to dissect the biological ...
  https://psychcentral.com/news/2012/10/11/gene-deletion-linked-to-mental-illness-obesity/45914.html
*  Frontiers | Conditional IL-2 Gene Deletion: Consequences for T Cell Proliferation | Immunology
... mice were created to allow conditional il2 gene deletion when treated with the estrogen analogue, tamoxifen (TAM) as adults. ... mice were created to allow conditional il2 gene deletion when treated with the estrogen analogue, tamoxifen (TAM) as adults. ... and to circumvent the IL-2 deficiency autoimmune syndrome of conventional il2 gene deletion, ... and to circumvent the IL-2 deficiency autoimmune syndrome of conventional il2 gene deletion, ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2012.00102/full
*  Need Help: Bacterial gene deletion- sacB sucrose resistance - Molecular Biology - BioForum
Bacterial gene deletion- sacB sucrose resistance - posted in Molecular Biology: Hi All, I have a problem regarding selecting ... a counterselectable gene promotes the death of the microorganisms harboring it. Hence, transformants which have integrated a ... The gene you're working with is a gene required for the bacterium to live under any condition, not simply a virulence gene ... has no sacB gene in it). I check for the gene knockout in 'centrimide+kan+amp' plate with PAO1 using the gene inserted suicide ...
  http://www.protocol-online.org/forums/topic/9924-need-help-bacterial-gene-deletion-sacb-sucrose-resistance/
*  Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions - Full Text View - ClinicalTrials.gov
Healthy normal volunteers, people with isolated aniridia, and people with WAGR or another chromosome 11 gene deletion may be ... The syndrome is caused by heterozygous contiguous gene deletions of variable size on chromosome 11, involving a region that ... Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions. This study has been completed. ... For WAGR/11p deletion subjects:. *Diagnosis of WAGR/11p deletion confirmed by prior genetic testing or clinical history ...
  https://clinicaltrials.gov/ct2/show/NCT00758108?recr=Open&cond=%22Wilms+Tumor%22&rank=17
*  NPM1 gene deletions in myelodysplastic syndromes with 5q- and complex karyotype | Haematologica
NPM1 gene deletions in myelodysplastic syndromes with 5q- and complex karyotype. Emanuele Ammatuna, Paola Panetta, Xabier ... NPM1 gene deletions in myelodysplastic syndromes with 5q- and complex karyotype. Emanuele Ammatuna, Paola Panetta, Xabier ... NPM1 gene deletions in myelodysplastic syndromes with 5q- and complex karyotype Message Subject (Your Name) has forwarded a ... we analyzed the NPM1 gene in terms of mutational and methylation status and presence of deletions in 53 patients with MDS or ...
  http://www.haematologica.org/content/early/2011/03/10/haematol.2010.038620
*  FRI0161 Sec16a Gene Deletion in A Large Axial Spondyloarthritis Family | Annals of the Rheumatic Diseases
The association of this deletion within the SEC16A gene with AxSpA is particularly interesting given that the gene product ... Although this in-frame deletion had no significant impact on gene or protein expression, a detrimental impact on protein ... The in-frame deletion had no significant impact on gene or protein expression. ... Gene expression profiling was performed using a Taqman Gene Expression Assay (Cat#4331182, SEC16A-Hs00389570_m1, GAPDH- ...
  http://ard.bmj.com/content/73/Suppl_2/440.2
*  Human Glucocorticoid Receptor Gene Deletion following Exposure to Cancer Chemotherapeutic Drugs and Chemical Mutagens | Cancer...
Human Glucocorticoid Receptor Gene Deletion following Exposure to Cancer Chemotherapeutic Drugs and Chemical Mutagens. Lisa A. ... Human Glucocorticoid Receptor Gene Deletion following Exposure to Cancer Chemotherapeutic Drugs and Chemical Mutagens ... Human Glucocorticoid Receptor Gene Deletion following Exposure to Cancer Chemotherapeutic Drugs and Chemical Mutagens ... Human Glucocorticoid Receptor Gene Deletion following Exposure to Cancer Chemotherapeutic Drugs and Chemical Mutagens ...
  http://cancerres.aacrjournals.org/content/52/23/6612
*  CD20 gene deletion causes a CD20-negative relapse in diffuse large B-cell lymphoma - Nakamaki - 2012 - European Journal of...
CD20 gene deletion causes a CD20-negative relapse in diffuse large B-cell lymphoma. Authors. *. Tsuyoshi Nakamaki,. ... Deletion of the CD20 gene is a molecular mechanism of CD20-negative relapse in a subset of DLBCL. ... showed homozygous deletion of the CD20 gene with loss of the copy number of 11q12. SD07 is the first case in which it is proven ... PCR assay for immunoglobulin (Ig) kappa (κ) chain gene rearrangement. Figure S2. The karyotype of the CD20-negative DLBCL cell ...
  http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0609.2012.01838.x/abstract
*  Constitutional and mosaic large NF1 gene deletions in neurofibromatosis type 1. | Journal of Medical Genetics
A set of neurofibromatosis type 1 (NF1) patients was screened for large NF1 gene deletions by comparing patient and parent ... indicative of NF1 gene deletion. These five patients did not have severe NF1 manifestations, mental retardation, or dysmorphic ... All five deletions were de novo and occurred on the maternal chromosome. However, two patients showed partial LOH, consistent ... We suggest that large NF1 deletions (1) are not always associated with unusual clinical features, (2) tend to occur more ...
  http://jmg.bmj.com/content/35/6/468
*  Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental...
Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental ... Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental ... Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental ... Gene deletion of the kinin receptor B1 attenuates cardiac inflammation and fibrosis during the development of experimental ...
  http://diabetes.diabetesjournals.org/content/early/2009/03/10/db08-0329
*  A Genetic Screen for Fission Yeast Gene Deletion Mutants Exhibiting Hypersensitivity to Latrunculin A | G3: Genes | Genomes |...
We obtained version 4 of the Bioneer gene deletion library (Kim et al. 2010) and carried out a screen for deletion mutants ... pombe genes of the Bioneer gene deletion set and analyzed using a hyper-geometric test. A multiple testing correction ( ... of nonessential Schizosaccharomyces pombe genes. Each strain carries a defined gene deletion constructed with the kanMX4 ... seven genes), and "regulation of adenylate cyclase activity" (six genes) (Figure 5C). Of the genes involved in chromatin ...
  http://www.g3journal.org/content/6/10/3399
*  Similarity of DMD gene deletion and duplication in the Chinese patients compared to global populations - Wang, Xiaozhu, Wang,...
Results Seventy-three percent of the subjects were found having a deletion (66.25%) or duplication (6.25%). ... DNA deletion and duplication were determined as the major mutation underlying Duchenne muscular dystrophy (DMD) and Becker ... Similarity of DMD gene deletion and duplication in the Chinese patients compared to global populations : ... Similarity of DMD gene deletion and duplication in the Chinese patients compared to global populations De Wang, Xiaozhu, Wang, ...
  http://www.youscribe.com/catalogue/documents/savoirs/similarity-of-dmd-gene-deletion-and-duplication-in-the-chinese-2035848
*  Construction of a Recyclable Genetic Maker and Serial Gene Deletions in the Human Pathogenic Mucorales Mucor circinelloides |...
Construction of a Recyclable Genetic Maker and Serial Gene Deletions in the Human Pathogenic Mucorales Mucor circinelloides. ... Construction of a Recyclable Genetic Maker and Serial Gene Deletions in the Human Pathogenic Mucorales Mucor circinelloides. ... Construction of a Recyclable Genetic Maker and Serial Gene Deletions in the Human Pathogenic Mucorales Mucor circinelloides. ... Construction of a Recyclable Genetic Maker and Serial Gene Deletions in the Human Pathogenic Mucorales Mucor circinelloides ...
  http://www.g3journal.org/content/early/2017/05/04/g3.117.041095
*  A Recessive Contiguous Gene Deletion of Chromosome 2p16 Associ...
Deletions ranging from 100 Kb to 1 Mb-too small ... A Recessive Contiguous Gene Deletion of Chromosome 2p16 ... A Recessive Contiguous Gene Deletion of Chromosome 2p16 Associated with Cystinuria and a Mitochondrial Disease. Publisher. The ... Deletions ranging from 100 Kb to 1 Mb-too small to be detected under the microscope-may still involve dozens of genes, thus ... which includes the type I cystinuria gene (SLC3A1), the protein phosphatase 2Cβ gene (PP2Cβ), an unidentified gene (KIAA0436), ...
  https://www.mysciencework.com/publication/show/a-recessive-contiguous-gene-deletion-of-chromosome-2p16-associated-with-cystinuria-and-a-mitochondrial-disease
*  Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary...
Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary ... Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary ... Slpi− / − mice had impaired collagen gene expression but animals demonstrated minimal reduction in lung fibrosis compared with ... Lung fibrosis was determined by collagen subtype-specific gene expression, hydroxyproline concentration, and histological ...
  http://eprints.nottingham.ac.uk/32862/
*  Chimeric Genes in Deletions and Duplications Associated with Intellectual Disability
Deletions and duplications are usually pathogenic when affecting dose-sensitive genes. Alternatively, a chimeric gene may also ... detected in 282 of the 384 validated cancer genes. Interstitial deletion can also generate fusion genes as described by Tomlins ... Chimeric Genes in Deletions and Duplications Associated with Intellectual Disability. Sonia Mayo, Sandra Monfort, Mónica ... Chimeric genes can have different possible consequences: when due to a deletion, not only the loss of a fully functional copy ...
  https://www.hindawi.com/journals/ijg/2017/4798474/
*  PreciseDeletion: Primers for seamless genome-wide gene deletion of genes
PreciseDeletion: Primers for seamless genome-wide gene deletion of genes. PreciseDeletion is a database of primers for the ... deletion of genes, according to the methods described in Aubrey et al. (2015) A Tool for Multiple Targeted Genome Deletions ...
  http://precise-deletion.dcs.aber.ac.uk
*  VHL gene deletion and enhanced VEGF gene expression detected i...
VHL gene deletion and enhanced VEGF gene expression detected in the stromal cells of retinal angioma.: These findings suggest ... VHL gene deletion and enhanced VEGF gene expression detected in the stromal cells of retinal angioma.. Authors * Chan, C C ...
  https://www.mysciencework.com/publication/show/vhl-gene-deletion-enhanced-vegf-gene-expression-detected-stromal-cells-retinal-angioma-13c46253
*  Behavioural and neurobiological consequences of macrophage migration inhibitory factor gene deletion in mice | Journal of...
In summary, we show that deletion of the MIF gene led to reduced behavioural despair in mice of both sexes, as assessed in the ... In summary, we found that mice with a genetic deletion of the MIF gene displayed reduced depressive-like behaviour in the FST. ... Behavioural and neurobiological consequences of macrophage migration inhibitory factor gene deletion in mice. ... Psychiatric symptoms have been shown to be associated with an IFN-γ gene (+874) T/A gene polymorphism, as hepatitis C patients ...
  https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-015-0387-4
*  Behavioural and neurobiological consequences of macrophage migration inhibitory factor gene deletion in mice - PDF
p , 0.05 compared to WT equivalents (n = 7 14 animals per group) Discussion In summary, we show that deletion of the MIF gene ... In summary, we found that mice with a genetic deletion of the MIF gene displayed reduced depressive-like behaviour in the FST. ... Gene Therapy. The use of DNA as a drug. Edited by Gavin Brooks. BPharm, PhD, MRPharmS (PP) Pharmaceutical Press Gene Therapy ... Gene Expression Application Note No. 4 Gene Expression Application Note No. 4 Relative Quantification of mirna Target mrnas by ...
  http://docplayer.net/2020557-Behavioural-and-neurobiological-consequences-of-macrophage-migration-inhibitory-factor-gene-deletion-in-mice.html
*  CRISPR-Cas9 mediated gene deletions in lager yeast Saccharomyces pastorianus | Microbial Cell Factories | Full Text
... pastorianus genes in the scientific literature based on impact of gene deletion [7-9]. Instead a S. pastorianus gene or allele ... This intricate genome organisation significantly complicates functional gene analysis. Indeed, a simple gene deletion based on ... 3c). In the meantime, mapping of the IMX1187 reads on the sequence of the deletion cassette including the cas9 and nat genes ... This strategy was tested by attempting deletion of the SeILV6 gene in IMX1187 (AaTEF1p-cas9). The S. pastorianus strain CBS1483 ...
  https://microbialcellfactories.biomedcentral.com/articles/10.1186/s12934-017-0835-1
*  Absence of a NPR-A Gene Functional Deletion Allele in a Postmyocardial Infarction Cohort From New Zealand | Circulation Research
Absence of a NPR-A Gene Functional Deletion Allele in a Postmyocardial Infarction Cohort From New Zealand. Barry R. Palmer, ... An 8-nucleotide deletion in the 5′ untranslated region (UTR) of the gene was found to be associated with essential hypertension ... Absence of a NPR-A Gene Functional Deletion Allele in a Postmyocardial Infarction Cohort From New Zealand ... Absence of a NPR-A Gene Functional Deletion Allele in a Postmyocardial Infarction Cohort From New Zealand ...
  http://circres.ahajournals.org/content/94/10/e86