GTPase-activating protein - Wikipedia
EIF5 is a GTPase-activating protein. Furthermore, YopE is a protein domain that is a Rho GTPase-activating protein (GAP), which ... GTPase-activating proteins or GTPase-accelerating proteins (GAPs) are a family of regulatory proteins whose members can bind to ... With a nonfunctional G protein enzyme, GAPs cannot activate the GTPase activity, and the G protein is constitutively on. This ... These G proteins acquire missense mutations that disrupt the inherent GTPase activity of the proteins. The mutant G proteins ...
Ras GTPase activating protein 1
Synonyms - GTPase-activating protein 1, Gap1 Cytological map position - 67D2--3 Function - Ras GTPase-activating protein ... The cloning and characterization of this protein reveals it to be a GTPase-activating protein, specifically a member of the ... a Ras GTPase-activating protein). No interactions were seen between Sprouty and several other proteins involved in the Ras ... A novel GTPase-activating protein (GAP) for Ras has been purified: it is immunologically distinct from the known Ras GAPs, ...
Zhouxiang Jin's Research on IQ motif containing GTPase activating protein 1
| CureHunter
IQ motif containing GTPase activating protein 1. 11/2014. Quercetin suppresses the proliferation of multiple myeloma cells by ... down-regulating IQ motif-containing GTPase activating protein 1 expression and extracellular signal-regulated kinase activation ... IQ motif containing GTPase activating protein 1IBA 11/2014 - 12/2013. ...
A Stretch of Polybasic Residues Mediates Cdc42 GTPase-activating Protein (CdGAP) Binding to Phosphatidylinositol 3,4,5...
Resveratrol induces apoptosis by directly targeting Ras-GTPase-activating protein SH3 domain-binding protein 1<...
Here, the Ras-GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) was identified as a potential target of ... Here, the Ras-GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) was identified as a potential target of ... Here, the Ras-GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) was identified as a potential target of ... Here, the Ras-GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) was identified as a potential target of ...
The potential probiotic Lactobacillus rhamnosus CNCM I-3690 strain protects the intestinal barrier by stimulating both mucus...
RAP1GAP-RAP1 GTPase-activating protein; RAPGEF3-Rap guanine nucleotide exchange factor 3; RGS14-regulator of G-protein ... 11 fibronectin-binding proteins (FBPs), 10 choline-binding proteins (CBPs), and 28 mucus-binding proteins (MBPs) (Fig. 1). They ... Waetzig, G. H. & Schreiber, S. Review article: mitogen-activated protein kinases in chronic intestinal inflammation - targeting ... resulting in decreased mucin production and reduced levels of tight-junction proteins, including occludin (a protein modulated ...
Ultrafast Two-Photon Imaging of a High-Gain Voltage Indicator in Awake Behaving Mice
3WPS: Crystal Structure Of The Gap Domain Of Mgcracgap(s387d)
A dominant mutation in the stereocilia-expressing gene TBC1D24 is a probable cause for nonsyndromic hearing impairment
MedlinePlus: Genes: S
RCSB PDB - 2GRQ: Crystal Structure of human RanGAP1-Ubc9-D127A
Ran GTPase-activating protein 1. B. 170. Homo sapiens. Mutation(s): 0 Gene Names: RANGAP1, KIAA1835, SD. ... E2 conjugating proteins that transfer ubiquitin and ubiquitin-like modifiers to substrate lysine residues must first activate ... E2 conjugating proteins that transfer ubiquitin and ubiquitin-like modifiers to substrate lysine residues must first activate ... It seems that Ubc9 uses an indirect mechanism to activate lysine for conjugation that may be conserved among E2 family members. ...
Rasal2 MGI Mouse Gene Detail - MGI:2443881 - RAS protein activator like 2
IPR001936 Ras GTPase-activating domain. IPR039360 Ras GTPase-activating protein. IPR023152 Ras GTPase-activating protein, ... protein coding gene. Chr1:156962752-157240170 (-). 129S1/SvImJ MGP_129S1SvImJ_G0016631. protein coding gene. Chr1:162141166- ... protein coding gene. Chr1:173635385-173956428 (-). DBA/2J MGP_DBA2J_G0016478. protein coding gene. Chr1:154558177-154836363 (-) ... protein coding gene. Chr1:160360737-160652455 (-). BALB/cJ MGP_BALBcJ_G0016573. protein coding gene. Chr1:156112395-156391089 ...
Wnt/β-catenin signaling pathway induces autophagy-mediated temozolomide-resistance in human glioblastoma | Cell Death & Disease
In this study, we demonstrated that the loss of DOC-2/DAB2 interacting protein (DAB2IP) is responsible for TMZ-resistance in ... Meanwhile, the DOC-2/DAB2 interacting protein DAB2IP was previously identified as a member of the Ras-GTPase activating protein ... Interaction of Disabled-1 and the GTPase activating protein Dab2IP in mouse brain. Brain Res Mol. Brain Res. 115, 121-129 (2003 ... Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2. J. Biol. Chem. 277, ...
Plastic Surgery for Capillary Malformations: Practice Essentials, Epidemiology, Etiology
The RASA1 gene encodes p120 Ras GTPase-activating protein. When mutated, p120 Ras GTPase-activating protein binds to Krev-1/ ... rap1a, an integrin β1-mediated cell adhesion and angiogenesis protein. The pathogenesis of capillary malformations is not ...
Son of Sevenless
GTPase activating protein. Chimerin 1 - RasGAP (Neurofibromin 1, IQ motif containing GTPase activating protein). ... The normal rate of Ras catalytic GTPase (GTP hydrolysis) activity can be increased by proteins of the RasGAP family, which bind ... Categories: Genes on chromosome 2 , Genes on chromosome 14 , GTP-Binding Protein Regulators , Proteins ... Thus, upon binding to GTP, the duration of Ras-GTPase activity is limited by the rate at which it hydrolyzes its bound GTP to ...
negative regulation of binding - Ontology Report - Rat Genome Database
Rap1 GTPase-activating protein. IMP. RGD. PMID:19066305. RGD:9835342. NCBI chr 5:149,873,987...149,939,254 Ensembl chr 5: ... Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine ... methyl CpG binding protein 2. IMP. RGD. PMID:24636259. RGD:12789709. NCBI chr X:151,781,177...151,844,687 Ensembl chr X: ... heat shock protein family A (Hsp70) member 4. IMP. Rela. RGD. PMID:17473852. RGD:5688754. NCBI chr10:37,408,025...37,449,080 ...
ADAP1 ORF clone FXC10551 - KOP/KDRI
Arf GTPase activating protein. HMMPfam. IPR001164. 8. 119. PF01412. Arf GTPase activating protein. ... ORF Protein. Cloned ORF protein sequence for pF1KB6565 Download >KIBB6565 374 aa ... Result of homology search against CCDS protein database ( FASTA output, Multiple alignment). ... Arf GTPase activating protein. IPR001164. 37. 54. PR00405. Arf GTPase activating protein. ...
Arhgap21
ARHGAP44 protein expression summary - The Human Protein Atlas
GTPase-activating protein (GAP) that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases ... Rho GTPase activating protein 44. Gene namei Official gene symbol, which is typically a short form of the gene name, according ... Protein evidence. Evidence at protein level (all genes). Number of transcriptsi Number of protein-coding transcripts from the ... Protein classi Assigned HPA protein class(es) for the encoded protein(s). ...
SCOPe 2.07: Domain d2g77a1: 2g77 A:246-442
PDB Compounds: (A:) GTPase-activating protein GYP1. SCOPe Domain Sequences for d2g77a1:. Sequence; same for both SEQRES and ... Other proteins in same PDB: d2g77b1. automated match to d1fkma1. complexed with af3, gdp, mg. ... Family a.69.2.1: Ypt/Rab-GAP domain of gyp1p [47924] (1 protein). duplication: contains two similar domains of this fold. ... Protein Ypt/Rab-GAP domain of gyp1p [47925] (1 species). *. Species Bakers yeast (Saccharomyces cerevisiae) [TaxId:4932] [ ...
Tissue expression of ARHGAP33 - Summary - The Human Protein Atlas
Rho GTPase activating protein 33. Predicted locationi All transcripts of all genes have been analyzed regarding the location(s ... Evidence at protein level. Protein expressioni A summary of the overall protein expression pattern across the analyzed normal ... RNA AND PROTEIN EXPRESSION SUMMARYi Below is an overview of RNA and protein expression data generated in the Human Protein ... Protein evidencei Evidence score for genes based on UniProt protein existence (UniProt evidence); neXtProt protein existence ( ...
MMRRC:040425-MU
Esben Lorentzen - Research - Aarhus University
IRA2 - COS12 Interaction Summary | BioGRID
CCS1, GLC4, Ras GTPase activating protein IRA2, L000000874, YOL081W. GTPase-activating protein; negatively regulates RAS by ... Protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins ... Ras GTPase activator activity [IDA, IMP]. Gene Ontology Cellular Component. *cytoplasm [IDA]*endoplasmic reticulum membrane [ ... negative regulation of Ras protein signal transduction [IMP]*negative regulation of cAMP biosynthetic process [IMP]*positive ...
Publications - Structural Cell Biology Section - NIDDK
Autoinhibition of Arf GTPase-activating protein activity by the BAR domain in ASAP1.. Jian X, Brown P, Schuck P, Gruschus JM, ... Membrane-bending proteins.. Prinz WA, Hinshaw JE.. Crit Rev Biochem Mol Biol (2009 Sep-Oct) 44:278-91. Abstract/Full Text. A ... Dynamins and BAR Proteins-Safeguards against Cancer.. Sundborger AC, Hinshaw JE.. Crit Rev Oncog (2015) 20:475-84. Abstract/ ... Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing.. Kitajiri S, Sakamoto T ...
Simon Cook - Publications | Babraham Institute
CAPRI is a member of the GAP1 family of GTPase-activating proteins (GAPs) for small G proteins. It is known to function as an ... Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP ... This activates the unfolded protein response (UPR) to re-establish the balance between ER protein folding capacity and protein ... demonstrate that the protein kinase MAP4K3 [mitogen-activated protein kinase kinase kinase kinase-3, a Ste20 family protein ...
ALSF Childhood Cancer Research Grants | Page 3 | Alex's Lemonade Stand Foundation for Childhood Cancer
Biomolecules | Free Full-Text | The Use of Euterpe oleracea Mart. As a New Perspective for Disease Treatment and Prevention
Dlc1Rho GTPase activating protein; Akt3: Akt serine/threonine kinase 3; DNA: deoxyribonucleic acid. DPPH: 2,2-diphenyl-1- ... Physical training enhanced the glucose-lowering effect, activating the phosphorylated adenosine monophosphate-activated protein ... NLRP3: nod-like receptor pyrin containing 3; p38-MAPK: p38 mitogen-activated protein kinase; NF-κB: nuclear factor κB; iNOS: ... 31], using BV-2 murine microglial cells, observed that the p38 mitogen-activated protein kinase (p38-MAPK) and the ...
RAB3GAP1 Antibody (NBP2-38206): Novus Biologicals
RAB3 GTPase activating protein subunit 1 (catalytic). *RAB3 GTPase-activating protein 130 kDa subunit ... Members of the RAB3 protein family (see RAB3A; MIM 179490) are implicated in regulated exocytosis of neurotransmitters and ... This antibody was developed against a recombinant protein corresponding to amino acids: ...