The DnaX ribosomal frameshifting element is a RNA element found in the mRNA of the dnaX gene in E. coli. The dnaX gene has two ... Page for DnaX ribosomal frameshifting element at Rfam v t e (Cis-regulatory RNA elements, All stub articles, Molecular and ... "Structural probing and mutagenic analysis of the stem-loop required for Escherichia coli dnaX ribosomal frameshifting: ... The gamma protein is synthesised due to programmed frameshifting and is shorter than tau. The two products of the dnaX gene are ...
Translational recoding or ribosomal frameshifting - a process when ribosomes either omit nucleotide(s)… ... provide genetic and biochemical evidence for ribosomal frameshifting in chloroplasts. Plant Cell https://doi.org/10.1093/plcell ...
1 Programmed Ribosomal Frameshifting as a Force-Dependent Process",. abstract = "−1 Programmed ribosomal frameshifting is a ... 1 programmed ribosomal frameshifting.. AB - −1 Programmed ribosomal frameshifting is a translational recoding event in which ... 1 programmed ribosomal frameshifting.",. keywords = "RNA, force, optical tweezers, single molecule, −1 programmed ribosomal ... 1 Programmed Ribosomal Frameshifting as a Force-Dependent Process. / Visscher, Koen. Nanotechnology Tools for the Study of RNA ...
1 ribosomal frameshifting (-1 PRF) was first identified in viruses. Early observations that global dysregulation of -1 PRF had ... Abstract Like most basic molecular mechanisms, programmed -1 ribosomal frameshifting (-1 PRF) was first identified in viruses. ...
Notably, we discovered a long-range RNA-RNA interaction, the FSE-arch, that encircles the programmed ribosomal frameshifting ...
Transfer RNA modification status influences retroviral ribosomal frameshifting. Virology 255, 2-8 (1999). ... Waas, W. F., Druzina, Z., Hanan, M. & Schimmel, P. Role of a tRNA base modification and its precursors in frameshifting in ... Smith, A. M., Jain, M., Mulroney, L., Garalde, D. R. & Akeson, M. Reading canonical and modified nucleobases in 16S ribosomal ... Tukenmez, H., Xu, H., Esberg, A. & Bystrom, A. S. The role of wobble uridine modifications in +1 translational frameshifting in ...
2 frameshifting was optimal at a spacer length 1-2 nucleotides shorter than that optimal for -1 frameshifting with all ... 2 frameshifting with stem-loop, pseudoknot or antisense oligonucleotide stimulators. By examining -1 and -2 frameshifting ... Here we examined frameshifting at the U6A slippery sequence of the HIV gag/pol signal and found high levels of both -1 and - ... Frameshifting signals comprise a heptanucleotide slippery sequence, where the ribosome changes frame, and a stimulatory RNA ...
2 ribosomal frameshifting on a U 6 A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting ... 2 ribosomal frameshifting on a U 6 A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting ...
Programmed ribosomal frameshifting mediates expression of the alpha-carboxysome. J. Mol. Biol. 428, 153-164 (2016). ...
The T-FRAME (Real-time analysis of ribosomal frameshifting and its impact on immunity and disease) project ends in 2026. For ... Real-time analysis of ribosomal frameshifting and its impact on immunity and disease ...
Brierley I, Boursnell ME, Binns MM, Bilimoria B, Blok VC, Brown TD, et al. An efficient ribosomal frame-shifting signal in the ... Characterization of an efficient coronavirus ribosomal frameshifting signal: requirement for an RNA pseudoknot. Cell. 1989;57: ... The ribosomal shift may have resulted in generation of the ORF1a/b protein encoding 19,962 nt and the deduced 6,653 aa. ... The coronaviruses have a pseudoknot tertiary structure that allows a ribosomal shift of the reading frame between ORF1a and ...
ZAP acts as an inhibitor of SARS-CoV-2 programmed ribosomal frameshifting. Nature Communications, December 2021. DOI: 10.1038/ ...
ribosomal frameshifting: A directed change in translational reading frame that allows the production of a single protein from ... ribosomal RNA rRNA genes: Gene categories ribosomal self-splicing RNA: Components of ribosomal RNA that undergo auto-catalyzed ... They are believed to have a catalytic function in reconstituting biologically active ribosomal subunits. MeSH 2003 ribosomal ... Abundant and functionally important types of non-coding RNAs include transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well ...
Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation., Gabriel Demo, Howard Gamper, Anna B. ... Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP, Christine E Carbone, Anna B Loveland, Howard Gamper ... Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA., Howard Gamper, Haixing Li, Isao Masuda, D ...
Additional targets include, inhibiting viral entry and unpackaging, ribosomal frameshifting, viral assembly and exit from the ...
NS1 of flaviviruses in the Japanese encephalitis virus serogroup is a product of ribosomal frameshifting and plays a role in ... may derive from ribosomal frameshifting. Virol. J. 2009, 6, 14. [Google Scholar] [CrossRef] [PubMed][Green Version] ... Song, Y.; Mugavero, J.; Stauft, C.B.; Wimmer, E. Dengue and Zika virus 5′ untranslated regions harbor internal ribosomal entry ... 1 ribosomal frameshift occurring at codons 8-9 of NS2A in JEV and WNV infection [63,123,124,125], because ZIKV lacks two ...
Accounting for programmed ribosomal frameshifting in the computation of codon usage bias indices [poster]. ... Accounting for programmed ribosomal frameshifting in the computation of codon usage bias indices. ... Accounting for programmed ribosomal frameshifting in the computation of codon usage bias indices. ...
Kendra JA, de la Fuente C, Brahms A, Woodson C. Ablation of Programmed -1 Ribosomal Frameshifting in Venezuelan Equine ...
Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based ... Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based ... Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based ... Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based ...
To do this, the novel coronavirus uses a process called programmed ribosomal frameshifting (PRF)-a topic that biophysicist ...
The short isoform of the host antiviral protein ZAP acts as an inhibitor of SARS-CoV-2 programmed ribosomal frameshifting. ...
Belew AT, Meskauskas A, Musalgaonkar S: Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway. ... Lagesen K, Hallin PF, Rødland E: RNAmmer: consistent and rapid annotation of ribosomal RNA Genes. Nucleic Acids Res 2007, 35: ... ribosomal structure, and biogenesis. In the metabolism module, 84 genes were associated with amino acid transport and ... ribosomal structure, and biogenesis. In the metabolism module, 12 genes were associated with amino acid transport and ...
Alam SL, Atkins JF, Gesteland RF: Programmed ribosomal frameshifting: Much ado about knotting! Proceedings of the National ... Harger JW, Meskauskas A, Dinman JD: An integrated model of programmed ribosomal frameshifting. Trends in Biochemical Sciences ... Farabaugh PJ: Programmed translational frameshifting. Annual Review of Genetics 1996, 30: 507-528. 10.1146/annurev.genet.30.1. ... 1 frameshifting, into VIEKgvsvpdp...(stop). While a diagnostic pseudoknot was discovered immediately downstream of the ...
"A new genomic RNA packaging element in retroviruses and the interplay with ribosomal frameshifting," published today in the ...
... foreign and blocking transcription of the protein it encodes has been found on some occasions to cause ribosomal frameshifting. ... foreign and blocking transcription of the protein it encodes has been found on some occasions to cause ribosomal frameshifting. ...
Viral ribosomal frameshifting signals, etc [2]. There are 26,704 sequences in 71 ncRNA seed families of Rfam 10.0 [3] ...
1 ribosomal frameshifting. Nucleic Acids Research 46 (16), S. 8079 - 8089 (2018) ... 1 programmed ribosome frameshifting on viral and bacterial mRNAs. FEBS Letters 593 (13), S. 1468 - 1482 (2019) ... Non-canonical binding site for bacterial initiation factor 3 on the large ribosomal subunit. Cell Reports 20 (13), S. 3113 - ... Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance. Nucleic Acids Research 47 (10), S. 5210 - 5222 (2019) ...
He was one of the first researchers to discover ribosomal frameshifting as a gene expression mechanism in plant RNA viruses and ...
Solenopsis invicta virus 3: mapping of structural proteins, ribosomal frameshifting, and similarities to Acyrthosiphon pisum ...
rogrammed -1 ribosomal frameshifting (PRF) in cardioviruses is activated by the 2A protein, a multi-functional virulence factor ... Thermodynamic control of -1 programmed ribosomal frameshifting.. Bock, Lars V; Caliskan, Neva; Korniy, Natalia; Peske, Frank; ... Programmed -1 ribosomal frameshifting (-1PRF) is a recoding mechanism to make alternative proteins from a single mRNA ... As an example, the interaction of the SARS-CoV-2 programmed ribosomal frameshifting element with the trans-acting factor short ...