DnaX ribosomal frameshifting element - Wikipedia
The DnaX ribosomal frameshifting element is a RNA element found in the mRNA of the dnaX gene in E. coli. The dnaX gene has two ... Page for DnaX ribosomal frameshifting element at Rfam v t e (Cis-regulatory RNA elements, All stub articles, Molecular and ... "Structural probing and mutagenic analysis of the stem-loop required for Escherichia coli dnaX ribosomal frameshifting: ... The gamma protein is synthesised due to programmed frameshifting and is shorter than tau. The two products of the dnaX gene are ...
Tag: ribosomal frameshifting | Plantae
Translational recoding or ribosomal frameshifting - a process when ribosomes either omit nucleotide(s)… ... provide genetic and biochemical evidence for ribosomal frameshifting in chloroplasts. Plant Cell https://doi.org/10.1093/plcell ...
1 Programmed Ribosomal Frameshifting as a Force-Dependent Process<...
1 Programmed Ribosomal Frameshifting as a Force-Dependent Process",. abstract = "−1 Programmed ribosomal frameshifting is a ... 1 programmed ribosomal frameshifting.. AB - −1 Programmed ribosomal frameshifting is a translational recoding event in which ... 1 programmed ribosomal frameshifting.",. keywords = "RNA, force, optical tweezers, single molecule, −1 programmed ribosomal ... 1 Programmed Ribosomal Frameshifting as a Force-Dependent Process. / Visscher, Koen. Nanotechnology Tools for the Study of RNA ...
Cell cycle control (and more) by programmed -1 ribosomal frameshifting: implications for disease and therapeutics.
The Short- and Long-Range RNA-RNA Interactome of SARS-CoV-2
The expanding world of tRNA modifications and their disease relevance | Nature Reviews Molecular Cell Biology
Transfer RNA modification status influences retroviral ribosomal frameshifting. Virology 255, 2-8 (1999). ... Waas, W. F., Druzina, Z., Hanan, M. & Schimmel, P. Role of a tRNA base modification and its precursors in frameshifting in ... Smith, A. M., Jain, M., Mulroney, L., Garalde, D. R. & Akeson, M. Reading canonical and modified nucleobases in 16S ribosomal ... Tukenmez, H., Xu, H., Esberg, A. & Bystrom, A. S. The role of wobble uridine modifications in +1 translational frameshifting in ...
Spacer-length dependence of programmed -1 or -2 ribosomal frameshifting on a U6A heptamer supports a role for messenger RNA ...
2 frameshifting was optimal at a spacer length 1-2 nucleotides shorter than that optimal for -1 frameshifting with all ... 2 frameshifting with stem-loop, pseudoknot or antisense oligonucleotide stimulators. By examining -1 and -2 frameshifting ... Here we examined frameshifting at the U6A slippery sequence of the HIV gag/pol signal and found high levels of both -1 and - ... Frameshifting signals comprise a heptanucleotide slippery sequence, where the ribosome changes frame, and a stimulatory RNA ...
Spacer-length dependence of programmed −1 or −2 ribosomal frameshifting on a U 6 A heptamer supports a role for messenger RNA ...
Reprogramming bacterial protein organelles as a nanoreactor for hydrogen production | Nature Communications
Shedding light on the HIV life cycle
Determination of Ferret Enteric Coronavirus Genome in Laboratory Ferrets - Volume 23, Number 9-September 2017 - Emerging...
Brierley I, Boursnell ME, Binns MM, Bilimoria B, Blok VC, Brown TD, et al. An efficient ribosomal frame-shifting signal in the ... Characterization of an efficient coronavirus ribosomal frameshifting signal: requirement for an RNA pseudoknot. Cell. 1989;57: ... The ribosomal shift may have resulted in generation of the ORF1a/b protein encoding 19,962 nt and the deduced 6,653 aa. ... The coronaviruses have a pseudoknot tertiary structure that allows a ribosomal shift of the reading frame between ORF1a and ...
Highlight Publications | News & Events | Helmholtz Centre for Infection Research
Pharmaceutical RNA glossary
ribosomal frameshifting: A directed change in translational reading frame that allows the production of a single protein from ... ribosomal RNA rRNA genes: Gene categories ribosomal self-splicing RNA: Components of ribosomal RNA that undergo auto-catalyzed ... They are believed to have a catalytic function in reconstituting biologically active ribosomal subunits. MeSH 2003 ribosomal ... Abundant and functionally important types of non-coding RNAs include transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well ...
Department of Biochemistry and Molecular Biology Faculty Papers | Department of Biochemistry and Molecular Biology | Thomas...
Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation., Gabriel Demo, Howard Gamper, Anna B. ... Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP, Christine E Carbone, Anna B Loveland, Howard Gamper ... Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA., Howard Gamper, Haixing Li, Isao Masuda, D ...
COVID-19 Research Registry | Letters | ASM.org
Viruses | Free Full-Text | Development, Characterization, and Application of Two Reporter-Expressing Recombinant Zika Viruses
NS1 of flaviviruses in the Japanese encephalitis virus serogroup is a product of ribosomal frameshifting and plays a role in ... may derive from ribosomal frameshifting. Virol. J. 2009, 6, 14. [Google Scholar] [CrossRef] [PubMed][Green Version] ... Song, Y.; Mugavero, J.; Stauft, C.B.; Wimmer, E. Dengue and Zika virus 5′ untranslated regions harbor internal ribosomal entry ... 1 ribosomal frameshift occurring at codons 8-9 of NS2A in JEV and WNV infection [63,123,124,125], because ZIKV lacks two ...
Research Centre of Bioinformatics | ZHAW Institute of Computational Life Sciences ICLS
Accounting for programmed ribosomal frameshifting in the computation of codon usage bias indices [poster]. ... Accounting for programmed ribosomal frameshifting in the computation of codon usage bias indices. ... Accounting for programmed ribosomal frameshifting in the computation of codon usage bias indices. ...
Western Equine Encephalitis: Background, Pathophysiology and Etiology, Epidemiology
Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles | HIV Testing Aidstar-One
Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based ... Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based ... Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based ... Production of the longer (PP1ab) or shorter protein (PP1a) depends on a -1 ribosomal frameshifting event. The proteins, based ...
Scientist searches for drug to prevent novel coronavirus from replicating | Faculty of Science
To do this, the novel coronavirus uses a process called programmed ribosomal frameshifting (PRF)-a topic that biophysicist ...
Pubblicazioni
Determination and Structural Analysis of the Whole-Genome Sequence of Fusarium equiseti D25-1 | Research Square
Belew AT, Meskauskas A, Musalgaonkar S: Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway. ... Lagesen K, Hallin PF, Rødland E: RNAmmer: consistent and rapid annotation of ribosomal RNA Genes. Nucleic Acids Res 2007, 35: ... ribosomal structure, and biogenesis. In the metabolism module, 84 genes were associated with amino acid transport and ... ribosomal structure, and biogenesis. In the metabolism module, 12 genes were associated with amino acid transport and ...
Complete genome sequence of the lytic Pseudomonas fluorescens phage ϕIBB-PF7A | Virology Journal | Full Text
Alam SL, Atkins JF, Gesteland RF: Programmed ribosomal frameshifting: Much ado about knotting! Proceedings of the National ... Harger JW, Meskauskas A, Dinman JD: An integrated model of programmed ribosomal frameshifting. Trends in Biochemical Sciences ... Farabaugh PJ: Programmed translational frameshifting. Annual Review of Genetics 1996, 30: 507-528. 10.1146/annurev.genet.30.1. ... 1 frameshifting, into VIEKgvsvpdp...(stop). While a diagnostic pseudoknot was discovered immediately downstream of the ...
Discovery in HIV may solve efficiency problems for gene therapy
BioWorld Science: The Daily Drug R&D News Source
Shape and secondary structure prediction for ncRNAs including pseudoknots based on linear SVM | BMC Bioinformatics | Full Text
Publikationen | Max-Planck-Institut für Multidisziplinäre Naturwissenschaften
1 ribosomal frameshifting. Nucleic Acids Research 46 (16), S. 8079 - 8089 (2018) ... 1 programmed ribosome frameshifting on viral and bacterial mRNAs. FEBS Letters 593 (13), S. 1468 - 1482 (2019) ... Non-canonical binding site for bacterial initiation factor 3 on the large ribosomal subunit. Cell Reports 20 (13), S. 3113 - ... Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance. Nucleic Acids Research 47 (10), S. 5210 - 5222 (2019) ...
Genetics | BIO5 Institute
He was one of the first researchers to discover ribosomal frameshifting as a gene expression mechanism in plant RNA viruses and ...
ICTV Virus Taxonomy Profile: Solinviviridae | Microbiology Society
Publications of the group Recoding mechanisms in infections ([HIRI]REMI)
rogrammed -1 ribosomal frameshifting (PRF) in cardioviruses is activated by the 2A protein, a multi-functional virulence factor ... Thermodynamic control of -1 programmed ribosomal frameshifting.. Bock, Lars V; Caliskan, Neva; Korniy, Natalia; Peske, Frank; ... Programmed -1 ribosomal frameshifting (-1PRF) is a recoding mechanism to make alternative proteins from a single mRNA ... As an example, the interaction of the SARS-CoV-2 programmed ribosomal frameshifting element with the trans-acting factor short ...