IJMS | Free Full-Text | Cocoa and Grape Seed Byproducts as a Source of Antioxidant and Anti-Inflammatory Proanthocyanidins
2.1.2. Flavonoids. Peaks 12, 18, 22 and 24 were determined as flavan-3-ol and derivatives. Peak 12 and 18 were characterized as ... flavonoids (flavan-3-ol, procyanidins and others flavonoids); and (3) other compounds. Note that a comprehensive ... The presence of the functional group "-OH" in the structure and its position on the ring of the flavonoid molecule determine ... Addition of "-OH" groups to the flavonoid nucleus will enhance the antioxidant activity, while substitution by -OCH3 groups ...
Nutrients | Free Full-Text | Flavonoids as Epigenetic Modulators for Prostate Cancer Prevention
Many dietary flavonoids have been found to reverse DNA aberrations that promote neoplastic transformation, particularly for PCa ... We overviewed the most recent evidence of the antitumoral effects exerted by dietary flavonoids, with a special focus on their ... The optimization of the use of flavonoids as natural epigenetic modulators for chemoprevention and as a possible treatment of ... Many research studies have highlighted the positive effects of natural flavonoids on chronic diseases, including PCa. Different ...
Processes | Free Full-Text | Optimization of Enzyme-Assisted Extraction of Flavonoids from Corn Husks
Overall, the results from this study indicate that corn husks are a valuable source of flavonoids and that they can be easily ... Although they are a rich source of bioactive compounds, especially flavonoids, corn husks are usually disposed of or used as ... about 1.3 g of total flavonoids per 100 g of dry waste were recovered. A statistical analysis of the results was performed to ... Determination of Total Flavonoid Content. Total flavonoids were determined according to the method proposed by Khorasani et al ...
Microbiology Research | Free Full-Text | Tannin-Tolerant Saccharomyces cerevisiae Isolated from Traditional Fermented Tea ...
... and flavonoids compared to S. cerevisiae TISTR 5088. This indicated its potential for high-tannin substrate-based bioconversion ... Total flavonoid. (μg QE/mL). 9.05 ± 0.15 a. 9.32 ± 0.19 a. 9.45 ± 0.56 a. 9.87 ± 0.23 a. 9.54 ± 0.82 a. 45.11 ± 0.73 a. 45.34 ... 2.8.3. Total Polyphenol, Total Tannin, and Total Flavonoid Contents. The total polyphenol (TP), total tannin (TT), and total ... and flavonoids [40,41]. Fruit wine production from Java plum has been previously reported, and the presence of ground seeds was ...
Plants | Special Issue : Antioxidant in Plants - Discovery, Biosynthesis, Regulation and Application
LC-HRMS/MS analysis of the nutmeg extracts noted fifteen metabolites (e.g., organic acids, flavonoids, phenolic acids, lignans ... The total flavonoid content (expressed as g rutoside/100 g dry extract) is similar for BE and LE (3.75 ± 0.3140 and 3.44 ± ... with a total phenolic and flavonoid content of 63.31 ± 0.72 mg GAE/g and 8.31 ± 0.06 mg RE/g, respectively. Moreover, it showed ... flavonoids, polyphenols, vitamins, quinones, coumarin, and alkenoic acid. ...
Nutrients | Free Full-Text | The Metabolomic-Gut-Clinical Axis of Mankai Plant-Derived Dietary Polyphenols
Figure 2. (A,B) Example of a UV spectra of the metabolites (experiment 4). (A). Flavonoid group quercetin and kaempferol ... Figure 2. (A,B) Example of a UV spectra of the metabolites (experiment 4). (A). Flavonoid group quercetin and kaempferol ... Chun, O.K.; Chung, S.J.; Song, W.O. Estimated dietary flavonoid intake and major food sources of US adults. J. Nutr. 2007, 137 ... Hooper, L.; Kroon, P.A.; Rimm, E.B.; Cohn, J.S.; Harvey, I.; Le Cornu, K.A.; Ryder, J.J.; Hall, W.L.; Cassidy, A. Flavonoids, ...
Pharmaceuticals | Special Issue : Grand Celebration: 100th Anniversary of the Discovery of Heparin
Special Issue in Molecules: Bioactive Flavonoids and Xanthones: From Bench to Industry. Pharmaceutical, Cosmetic and Industrial ... Interests: medicinal chemistry; organic synthesis; natural products; xanthones; flavonoids; antimicrobials; antitumor; ...
Nutrients | Free Full-Text | Phytomedicine in Joint Disorders
phenols, flavonoids. (−) NO, TNF-α, IL-1β, IL-6, IL-12, anti-type II collagen antibodies, (+) antioxidants (AM). [24]. ... salicin, polyphenols, flavonoids. (−) TNFα, COX-2, IL-1, IL-6 (in vitro). [87,95]. ... The anti-arthritic efficiency is attributed by some authors to a synergism of phenolic and flavonoid compounds, the dominant ... such as polyphenols and flavonoids, which showed inhibitory activity on COX-2 and decreased synthesis of pro-inflammatory ...
Biomolecules | Free Full-Text | Evaluation of Halophyte Biopotential as an Unused Natural Resource: The Case of Lobularia...
The antimicrobial properties of plants may be associated with their content of secondary metabolites such as flavonoids and ... TP, total phenols; TF, total flavonoids; CT, condensed tannins; GAE, gallic acid equivalent; CE, catechin equivalent; PG, ... total flavonoids 35 ± 2.88 mg QE/g DW) the extract was found to be an active radical scavenger in in vitro tests (DPPH, lipid ... flavonoids, and vitamins, are much more resistant to salt stress [34,123]. Previous studies have shown that salt treatment (200 ...
Molecules | Free Full-Text | Mechanism Investigation of Tagetes patula L. against Chronic Nonbacterial Prostatitis by...
Generally, the potential anti-CNP mechanism of flavonoids and polysaccharides of T. patula might be through reducing the ... The study demonstrated that the flavonoids and polysaccharides of T. patula could alleviate prostatitis by improving the level ... The flavonoids in T. patula can also reduce the increasing of TNF-α levels caused by CNP. Here we supposed that the flavonoids ... The structure of flavonoids usually contains phenolic hydroxyl and ketone carbonyl, which have antioxidant effects in the study ...
IJMS | Free Full-Text | Bioactivities of Phenolics by Focusing on Suppression of Chronic Diseases: A Review
Phenolic acids, flavonoids, and tannins. Anticancer. [101]. Indian gooseberry. Phenolic acids and flavonoids. Anticancer. [101] ... Flavonoids biosynthesis, referred to as the flavonoid branch pathway, starts with a combination of three molecules of malonyl ... Flavonoids and breast cancer risk in Italy. Cancer Epidemiol. Biomark. Prev. 2005, 14, 805-808. [Google Scholar] [CrossRef] [ ... Phenolic acids, flavonoids, and anthocyanins. Anti-inflammation. [97]. Red bean. Catechin-7-β-d-glucopyranoside. Anti- ...
Pharmaceutics | Free Full-Text | Quercetin Loaded Monolaurate Sugar Esters-Based Niosomes: Sustained Release and Mutual...
... in this work niosomes have been selected to encapsulate the hepatoprotective natural flavonoid quercetin. The aim of this study ... Flavonoids possess different interesting biological properties, including antibacterial, antiviral, anti-inflammatory and ... Panche, A.; Diwan, A.; Chandra, S. Flavonoids: An overview. J. Nutr. Sci. 2016, 5, e47. [Google Scholar] [CrossRef][Green ... Kumar, S.; Pandey, A.K. Chemistry and biological activities of flavonoids: An overview. Sci. World J. 2013, 2013, 162750. [ ...
Processes | Free Full-Text | Comparison of Different Extraction Methods for the Recovery of Olive Leaves Polyphenols
Ioannou, I.; Ghoul, M. Biological activities and effects of food processing on flavonoids as phenolics antioxidants. Adv. Appl ... flavonoids (e.g., RT) are more sensitive to thermal degradation than phenolic acids [28]. The elevated temperature usually ... flavonoids and secoiridoids, are the ones responsible for these various positive properties. Several studies have reported the ...
Molecules | Free Full-Text | Comparative Interaction Studies of Quercetin with 2-Hydroxyl-propyl-β-cyclodextrin and 2,6...
Havsteen, B.H. The biochemistry and medical significance of the flavonoids. Pharmacol. Ther. 2002, 96, 67-202. [Google Scholar ... Andersen, Ø.M.; Markham, K.R. (Eds.) Flavonoids: Chemistry, Biochemistry, and Applications; CRC, Taylor & Francis: Boca Raton, ... Like many flavonoids, QUE is best known for its antioxidant activity [4,5,6], suggesting that it could be used in preserving ...
IJMS | Free Full-Text | Managing Phenol Contents in Crop Plants by Phytochemical Farming and Breeding-Visions and Constraints
Dietary flavonoids and heath-Broadening the perspective. In Flavonoids Chemistry, Biochemistry and Applications; Andersen, OM, ... Forkmann, G. Genetics of flavonoids. In The Flavonoids; Harborne, JB, Ed.; Chapman and Hall: London, UK, 1993; pp. 537-564. [ ... Bohm, B. The minor flavonoids. In Flavonoids: Advances in Research since 1986; Harborne, JB, Ed.; Chapman & Hall: London, UK, ... Heller, W; Forkmann, G. Biosynthesis of flavonoids. In Flavonoids: Advances in Research since 1986; Harborne, JB, Ed.; Chapman ...
Molecules | Free Full-Text | Cuscuta chinensis and C. campestris Attenuate Scopolamine-Induced Memory Deficit and Oxidative...
The total flavonoid content of C. chinensis and C. campestris extracts was determined to be 20.07 ± 0.22 and 28.34 ± 0.95 mg/g ... Zhen, G.H.; Jiang, B.; Bao, Y.M.; Li, D.X.; An, L.J. The protect effect of flavonoids from Cuscuta chinensis in PC12 cells from ... The total flavonoid content in the extract was determined using the aluminum chloride colorimetric assay [35]. The content of ... Yang, D.; Wang, G.M.; Zhai, H.Y. Effects of Cuscuta chinensis flavonoids on inflammatory response of brain tissue in rats with ...
JCM | Free Full-Text | The Role of Antioxidants on Wound Healing: A Review of the Current Evidence
Tran, H.A.; Ly, K.L.; Fox, K.E.; Tran, P.A.; Nguyen, T.H. Immobilization of Antimicrobial Silver and Antioxidant Flavonoid as a ... Quercetin is a flavonoid compound commonly found in vegetables and fruits. It has strong antioxidant and anti-inflammatory ... Non-enzymatic antioxidants are low molecular weight compounds, such as vitamin E, vitamin C, glutathione and flavonoids. ... the antioxidant flavonoid quercetin. In vitro antibacterial assay results showed that the synergism of Ag and quercetin ...
Cells | Free Full-Text | Enhancing Salt Tolerance of Plants: From Metabolic Reprogramming to Exogenous Chemical Treatments and...
Gould, K.S.; Lister, C. Flavonoid functions in plants. In Flavonoids. Chemistry, Biochemistry, and Applications; Andersen, Ø.M ... increased flavonoid levels may help plants counter stress-induced oxidative damage [94,97]. Some flavonoids can act as ... Panche, A.N.; Diwan, A.D.; Chandra, S.R. Flavonoids: An overview. J. Nutr. Sci. 2016, 5, e47. [Google Scholar] [CrossRef][Green ... Agati, G.; Biricolti, S.; Guidi, L.; Ferrini, F.; Fini, A.; Tattini, M. The biosynthesis of flavonoids is enhanced similarly by ...
Molecules | Free Full-Text | Response of Phenylpropanoid Pathway and the Role of Polyphenols in Plants under Abiotic Stress
Plants exhibit increased synthesis of polyphenols such as phenolic acids and flavonoids under abiotic stress conditions, which ... Increase in contents of total phenols and flavonoids.. [115]. Brassica napus. Increase in contents of total phenols, flavonoid ... Increase in the contents of total flavonoids and anthocyanins.. [90]. Cd. Increase in total contents of flavonoids and ... Increase in contents of total phenols and flavonoids.. [136]. Chenopodium quinoa. Increase in total polyphenol and flavonoid ...
Molecules | Free Full-Text | Effects of Honey and Its Mechanisms of Action on the Development and Progression of Cancer
2. Structures of Major Flavonoids and Phenolic Acids in Honey. Flavonoids refer to a group of biologically active natural ... especially flavonoids and phenolic constituents. Some of the flavonoids and phenolic compounds that have been identified in ... Angst, E.; Park, J.L.; Moro, A.; Lu, Q.Y.; Lu, X.; Li, G.; King, J.; Chen, M.; Reber, H.A.; Go, V.L.; et al. The flavonoid ... Chan, C.W.; Deadman, B.J.; Manley-Harris, M.; Wilkins, A.L.; Alber, D.G.; Harry, E. Analysis of the flavonoid component of ...
Biomolecules | Free Full-Text | The Use of Euterpe oleracea Mart. As a New Perspective for Disease Treatment and Prevention
Kang, J.; Xie, C.; Li, Z.; Nagarajan, S.; Schauss, A.G.; Wu, T.; Wu, X. Flavonoids from açai (Euterpe oleracea Mart.) pulp and ... Flavonoids present in the EO juice may have been responsible for the observed property [26]. ... Five flavonoids were isolated and structurally identified. ORAC values varied significantly based on their chemical structures ... 31] reported the presence of the flavonoid quercetin and anthocyanins, such as cyanidin-3-glucoside and cyanidin-3-rutinoside ( ...
Molecules | February 2018 - Browse Articles
This review focuses on sulphated flavonoids, an uncommon group of flavonoid derivatives found in some plant families. This work ... Nine flavonoids were isolated and identified from a chloroform-soluble fraction of the roots of Scutellaria baicalensis through ... Nine flavonoids were isolated and identified from a chloroform-soluble fraction of the roots of Scutellaria baicalensis through ... Flavonoids, for example, can be found as aglycone or as several sorts of glycosylated, acetylated, methylated, and sulphated ...
Molecules | Free Full-Text | Physicochemical and Antioxidant Properties of Black Garlic
Antioxidant components, including the total polyphenol and total flavonoids contents of BG, increased significantly until the ... flavonoids, and anthocyanins, and that this is connected to the type and duration of treatment. Flavonoids do not only belong ... Total flavonoid (mg RE/g). 3.22 ± 0.07 d. 5.38 ± 0.06 c. 8.34 ± 0.61 b. 15.37 ± 0.52 a. 16.26 ± 1.69 a. 15.70 ± 2.11 a. ... The total flavonoids content was analyzed according to the method described by Shen et al. [31]. Deionized water (2 mL) and 0.5 ...
IJERPH | Special Issue : Endocrine Disruptors and Public Health
Some flavonoids exhibit binding to estrogen receptors (ERs) with [...] Read more. Flavonoids are frequently used as dietary ... database for 22 flavonoids that bind ERs. The selected flavonoids are confirmed ER binders from our earlier studies, and were ... Some flavonoids exhibit binding to estrogen receptors (ERs) with consequential vigilance by regulatory authorities at the U.S. ... Flavonoids are frequently used as dietary supplements in the absence of research evidence regarding health benefits or toxicity ...
Cells | Special Issue : Natural Products in the Treatment of Cancer
Flavonoids exert many beneficial properties, such as anticancer activity. They were found to have chemopreventive effects ... Flavonoids exert many beneficial properties, such as anticancer activity. They were found to have chemopreventive effects ... There are also reports on the chemosensitizing properties of flavonoids, which indicate that they could be used as a support of ...
Nutrients | Free Full-Text | Patient Nutrition and Probiotic Therapy in COVID-19: What Do We Know in 2021?
González-Gallego, J.; Sánchez-Campos, S.; Tuñón, M.J. Anti-Inflammatory Properties of Dietary Flavonoids. Nutr. Hosp. 2007, 22 ...
Nutrients | Free Full-Text | A Specific Melon Concentrate Exhibits Photoprotective Effects from Antioxidant Activity in Healthy...
Patwardhan, J.; Bhatt, P. Ultraviolet-B Protective Effect of Flavonoids from Eugenia caryophylata on Human Dermal Fibroblast ...
Processes | Free Full-Text | Flow Characteristics and Stress Analysis of a Parallel Gate Valve
Optimization of Enzyme-Assisted Extraction of Flavonoids from Corn Husks. Next Article in Special Issue. Natural Frequency ...
Metabolites | Free Full-Text | Interlaboratory Coverage Test on Plant Food Bioactive Compounds and Their Metabolites by Mass...
Several flavonoids, such as genistein, bergaptol and luteolin, and some phenolic acids (ferulic and p-coumaric acid), were ... For flavonoids, the elution order has been established at a subclass level for RP-LC as follows: flavanols , flavanones , ... Flavonoids are a chemically diverse group, ranging from relatively lipophilic aglycones, such as genistein, to more complex ... Figure 6. The elution order of flavonoids (A) and three pairs of closely eluting compounds representing different compound ...
IJMS | Free Full-Text | Peimine, an Anti-Inflammatory Compound from Chinese Herbal Extracts, Modulates Muscle-Type Nicotinic...
... which are flavonoids present in Fb [40]. Noticeably, some flavonoids act as positive allosteric modulators of α7 nAChRs, ... Iwashina, T. Flavonoid function and activity to plants and other organisms. Biol. Sci. Space 2003, 17, 24-44. [Google Scholar ... Nielsen, B.; Bermudez, I.; Bouzat, C. Flavonoids as positive allosteric modulators of α7 nicotinic receptors. Neuropharmacology ... and some flavonoids, as quercetin or genistein, act as positive allosteric modulators of α7 nicotinic receptors [6], and (iv) ...