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*  Diffuse esophageal spasm: a case study
The esophagus functions to transport food and liquid from the pharynx to the stomach. It is comprised of striated and smooth muscle and has specialized sphincters at its proximal (upper) and distal (lower) ends. Its muscle action produces the sequential, coordinated peristalsis that propels food and liquid distally. This peristaltic movement needs to have coordinated primary and secondary contractions. When these do not occur, tertiary contractions result. These contractions are dysfunctional and create a motility disorder of the esophagus. One such motility disorder is Diffuse Esophageal Spasm (DES). Symptoms of DES include atypical chest pain that can mimic angina, and dysphagia (swallowing difficulty), particularly a feeling of food or liquid being caught in the throat. DES is best confirmed through manometry, a procedure that assesses pressure, timing, and intensity of esophageal muscle movement, and radiography, or imaging, of the ...
  https://soar.wichita.edu/handle/10057/3564
*  What are esophageal spasms? | Reference.com
Esophageal spasms occur when normal contractions of the esophagus become irregular, uncoordinated or stronger than normal, according to the Norris Cotton Cancer Center. Diffuse esophageal spasm and...
  https://www.reference.com/health/esophageal-spasms-b99b494080e95aa
*  Swallowing Disorders/Dysphagia | Columbia University Department of Surgery
Difficulty swallowing, also called dysphagia, may indicate a problem in the throat or esophagus. There are many causes of dysphagia, including the following: Diffuse Esophageal Spasm (DES) In diffuse Esophageal Spasm (DES), abnormal spasms of the esophagus keep swallowed food from reaching the stomach. Nutcracker Esophagus In nutcracker esophagus, muscles of the esophagus contract too powerfully. The condition is frequently related to GERD. Scleroderma
  http://columbiawoundhealing.org/conditions-and-treatments/swallowing-disordersdysphagia
*  Most recent papers with the keyword Esophageal spasm | Read by QxMD
Distal esophageal spasm (DES) is a primary esophageal motility disorder. We encountered a rare case of DES accompanied by multiple esophageal diverticula. A 72-year-old woman complained of prolonged dysphagia and chest pain. A barium esophagogram showed multiple esophageal diverticula and significant contraction of the lower esophagus just above the cardia. Esophagogastroduodenoscopy revealed a corkscrew-like appearance, with spiral contractions and diverticula. High-resolution manometry revealed that the integrated relaxation pressure was normal; premature contractions were observed in ≥20% of the swallowing wave; the distal contractile integral was normal ...
  https://www.readbyqxmd.com/keyword/87309
*  Comparison of Esophageal and Anorectal Manometry Catheters - Tabular View - ClinicalTrials.gov
Twenty subjects with abnormal esophageal motility (5 subjects each with achalasia, nutcracker esophagus, scleroderma, diffuse esophageal spasm or hypertensive LES) previously referred for clinical esophageal motility testing will be contacted. These twenty subjects must have previously undergone esophageal manometry testing using the standard clinical protocol at the University of Utah motility with solid state manometry catheters. After obtaining informed consent, these twenty subjects will undergo the esophageal manometry using air-filled balloon catheters per the standard clinical protocol. Following the repeat procedure a short one-page questionnaire will be completed by the subject and the motility nurse.. Five subjects with the diagnosis of incontinence previously referred for clinical anorectal motility testing will be contacted. These five subjects must have previously undergone ...
  https://clinicaltrials.gov/ct2/show/record/NCT00204763
*  Comparison of Esophageal and Anorectal Manometry Catheters - Full Text View - ClinicalTrials.gov
Twenty subjects with abnormal esophageal motility (5 subjects each with achalasia, nutcracker esophagus, scleroderma, diffuse esophageal spasm or hypertensive LES) previously referred for clinical esophageal motility testing will be contacted. These twenty subjects must have previously undergone esophageal manometry testing using the standard clinical protocol at the University of Utah motility with solid state manometry catheters. After obtaining informed consent, these twenty subjects will undergo the esophageal manometry using air-filled balloon catheters per the standard clinical protocol. Following the repeat procedure a short one-page questionnaire will be completed by the subject and the motility nurse.. Five subjects with the diagnosis of incontinence previously referred for clinical anorectal motility testing will be contacted. These five subjects must have previously undergone ...
  https://clinicaltrials.gov/show/NCT00204763
*  Article - Eosinophilic Esophagitis
Gastroenterology Esophageal and Swallowing Disorders Gastrointestinal Motility Disorders Heartburn, Achalasia Dr. Arnon Lambroza is a gastroenterologist who specializes in esophageal and swallowing disorders, including gastroesophageal reflux disease, Barrett's esophagus, achalasia and diffuse esophageal spasm. He is also an expert in the diagnosis and treatment of gastrointestinal motility disorders such as gastroparesis (delayed gastric emptying), irritable bowel syndrome and constipation.
  http://lambroza.com/index.php/eosinophilic-esophagitis/article-eosinophilic-esophagitis
*  Chest discomfort, nausea, probable esophageal spasm? - Online Doctor Chats
Online Doctor Chat - Chest discomfort, nausea, probable esophageal spasm?, Ask a Doctor about diagnosis, treatment and medication for Heart attack, Online doctor patient chat conversation by Dr. Prasad
  http://www.healthcaremagic.com/doctorchatlogs/Chest-discomfort-nausea-probable-esophageal-spasm/53768
*  HOW CAN I STOP THE PAIN OF ESOPHAGEAL SPASMS - Digestive Disorders / Gastroenterology - MedHelp
I have esophageal spasms. They feel just like a heart attack or that you are having labor in your chest. They last for about an hour. It is a tremendous pain. I have taken prilosec, zantac, nexium,...
  http://www.medhelp.org/posts/Digestive-Disorders---Gastroenterology/HOW-CAN-I-STOP-THE-PAIN-OF-ESOPHAGEAL-SPASMS/show/233164
*  Esophageal spasm? - Digestive Disorders / Gastroenterology - MedHelp
I have recently been diagnosed with esophageal spasms. After reading many of the postings here I am concerned that I may have to continue to live with this. What are the options? Does it e...
  http://www.medhelp.org/posts/Digestive-Disorders---Gastroenterology/Esophageal-spasm/show/885460
*  What are some remedies for relieving esophageal spasms? | Reference.com
For most cases of esophageal spasms, doctors recommend that patients avoid certain foods or situations that can trigger an attack, notes Mayo Clinic. Doctors also recommend that the patient treats...
  https://www.reference.com/health/remedies-relieving-esophageal-spasms-9374d32adf0f0644
*  High Resolution Manometry Vs Conventional Line Tracing for Esophageal Motility Disorders - Gastroenterology & Hepatology
G&H How are the various esophageal motility disorders classified?. RY The Chicago Classification categorizes esophageal motility disorders based on high resolution manometry esophageal pressure topography metrics. The Chicago Classification was first introduced in 2009 and is based on the work of the International High Resolution Manometry Working Group. The Chicago Classifica-tion has since undergone updates and is currently in version 3.0.. G&H When is esophageal manometry recommended?. RY Esophageal manometry is used to assess non-obstructive dysphagia, esophageal motility prior to antireflux intervention or surgery, symptoms such as regurgitation, heartburn, and noncardiac chest pain, and gastroesophageal reflux disease nonresponsive to proton pump inhibitor therapy.. G&H How does high resolution manometry compare to conventional line tracing?. RY Esophageal manometry ...
  http://www.gastroenterologyandhepatology.net/archives/march-2017/high-resolution-manometry-vs-conventional-line-tracing-for-esophageal-motility-disorders/
*  Esophageal Muscle Spasms: Home Care
Another name for Esophageal Muscle Spasms is Esophageal Spasm. Home care for esophageal spasm includes: * Ask your doctor to prescribe your medications ...
  http://www.freemd.com/esophageal-muscle-spasms/home-care.htm
*  Botulinum Toxin Injection in Hypercontractile Esophagus - Full Text View - ClinicalTrials.gov
Eligible patients will present chest pain and/or dysphagia related to the following hypercontractile esophageal motility disorders: distal esophageal spasm, jackhammer esophagus, nutcracker esophagus or type III achalasia with normalization of the integrated relaxation pressure after treatment, based on the Chicago classification of esophageal motility disorders for high resolution manometry (HRM). Upper gastrointestinal endoscopy and barium swallow will be performed before BTX injection to eliminate secondary disorders.. This is a prospective, randomized, double blind, controlled trial comparing BTX injection to sham procedure (absence of injection, the clinical team performing the follow-up will not be aware of the result of the randomization).. Drugs which could affect esophageal motility (nitrates and calcium channel blockers) will be stopped during the study.. Included patients will undergo esophageal ...
  https://clinicaltrials.gov/ct2/show/NCT01955174?recr=Open&intr=botulinum+toxin&rank=8
*  Esophageal Muscles
The esophageal muscles line the esophagus just above the point where it joins the stomach. The circular muscle fibers in the esophageal muscle walls are thickened. These fibers are usually contracted, and function to close the entrance to the stomach. In this way, they help prevent regurgitation of the stomach contents into the esophagus. When peristaltic waves reach the stomach, the muscle fibers Continue Scrolling To Read More Below... ...
  http://www.innerbody.com/image_dige01/musc32-new.html
*  Muscle Spasms Esophagus: Incidence
Another name for Muscle Spasms Esophagus is Esophageal Spasm. Facts about esophageal spasm: * About 1 out of 1,000 people in the US have an esophageal ...
  http://www.freemd.com/muscle-spasms-esophagus/incidence.htm
*  Achalasia, Esophageal Spasm and EoE oh my! | The (unofficial) University of Texas Southwestern Internal Medicine Blog
Today in VA morning report we had a lively discussion about esophageal problems with the lead discussant being our local esophagus expert Dr. Dunbar! Some quick PEARLS below! Achalasia - Typically presents with dysphagia to both solids and liquids Represents failure of relaxation of the LES (in most cases) Remember to perform an EGD on…
  https://utswim.wordpress.com/2017/07/25/achalasia-esophageal-spasm-and-eoe-oh-my/
*  Esophageal Spasms Or Heart Palpitations? - Sclero Forums (MAIN) - Sclero Forums
I feel a fluttering in the center of my chest but no pain. I've felt this many years ago too. Once it felt like my heart did a slow roll inside my chest, ...
  https://www.sclero.org/forums/topic/1004-esophageal-spasms-or-heart-palpitations/
*  Calcium Sensitization in Human Esophageal Muscle: Role for RhoA Kinase in Maintenance of Lower Esophageal Sphincter Tone |...
Pharmacological evidence for Ca2+ sensitization was demonstrated based on sensitivity of esophageal muscle to two different RhoA-kinase inhibitors. Both Y-27632 and HA-1077 significantly attenuated contraction over a range of concentrations 100-fold lower than that found to inhibit PKC, consistent with their selective inhibition of RhoA kinase in other smooth muscles (Rattan et al., 2003; Somlyo and Somlyo, 2003; Shabir et al., 2004; Gokina et al., 2005; Harnett et al., 2005). Contractions elicited by different stimuli showed similar sensitivity, showing internal consistency. Effects on muscle contraction elicited by external application of muscarinic agonist were similar to those elicited by EFS of intrinsic nerves. Such nerve-mediated contractions are largely blocked by atropine, indicating muscarinic signaling (Krysiak and Preiksaitis, 2001; Kovac et al., 2006). The atropine-insensitive contraction includes a component due to tachykinins acting on NK2 receptors (Farré and Sifrim, 2008), ...
  http://jpet.aspetjournals.org/content/327/1/178.full
*  Tips From Other Journals - American Family Physician
Chest pain is a common reason for hospital admission. In most patients with chest pain, acute coronary artery disease (CAD) is the major concern. Nitrates often are used in emergency treatment of acute chest pain, but relief with nitrates is an uncertain diagnostic and prognostic sign. Because nitro-glycerin can relieve symptoms of noncardiac chest pain, including esophageal spasm, its value as a tool in the diagnosis of ischemic heart disease is questionable. Henrikson and associates conducted a prospective study to determine the usefulness of chest pain response to nitroglycerin as an indicator of ischemic coronary disease.. Patients who had documented chest pain while under medical supervision were given nitroglycerin. A chest pain response to the first dose of nitroglycerin was defined as a 50 percent or greater decrease in pain intensity within five minutes of nitroglycerin administration. The presence of active CAD was determined for all participants. Active CAD was ...
  https://www.aafp.org/afp/2004/0701/p182.html
*  Bulging disk chest pain - Things You Didn't Know
Bulging disk chest pain - I get immediate bulge in stomach after eating anything. Also get pain right below the left rib just above the stomach. Feels like I have a chest pain? Esophageal/gastic? You should see your doc and get an evaluation. This is unlikely to be cardiac but esophageal spasm, various gastic problems and perhaps other things could do this.
  https://www.healthtap.com/topics/Bulging-disk-chest-pain
*  Zenegra For Sale. Zenegra - Multitut
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  http://multitut.com/forums/topic/zenegra-for-sale-zenegra/
*  Thoracic Diaphragm Facts - Interesting Facts
Diaphragm is a dome shaped structure which has several large muscles which naturally separates any two adjacent parts in a human body or body of the mammals. The thoraco abdominal diaphragm is the commonly known muscle. Considering a human body, these muscles serve to part the cavity of the chest from that of the abdomen. The diaphragm top is located one and one and a half inches from the bottom of the sternum supports the heart, and diaphragm bottom is attached round the lower ribs connecting to the lower lumbar vertebrae. Being the chief part of the respiration process in humans, these muscles rest into dome shape during exhalation. It contracts when air is inhaled; it lets the chest cavity expand by a simultaneous contraction of the chest muscles. When air is deeply inhaled followed by the expansion of the belly while inhalation and retraction, while exhalation, the diaphragm moves further down into the abdomen, thereby making the lungs expand completely in the chest cavity. This suggests ...
  http://www.interestingfacts.org/fact/thoracic-diaphragm-facts
*  Anomaly of an Orange Life: Let's talk GERD **part THREE**
Basically my esophagus does not perform peristalsis like it should which means if I had the procedure Dr. Evans knew how to do, I would not be able to push food, liquid, etc. from my esophagus to my stomach. That's bad. To further complicate issues I have esophageal muscle weakness. So in other words not only does it not do what it is supposed to, it doesn't have enough muscle to do it correctly even if it was doing what it should. He goes on to explain to me the type of procedure I need, but that he isn't sure if anyone in York does it. He left the room to make some phone calls to local surgeons. When he came back, no one was available for him to talk to, but he told me he would continue to call around until he found someone willing to do the procedure. He said he might have to send me to Hershey or Hopkins. *whimper* WHY can't this just be easy ...
  http://anomalyofanorangelife.blogspot.com/2009/02/lets-talk-gerd-part-three.html