Ephrin-A2 is a protein that in humans is encoded by the EFNA2 gene. This gene encodes a member of the ephrin family. The ... "Entrez Gene: EFNA2 ephrin-A2". Flanagan JG, Vanderhaeghen P (1998). "The ephrins and Eph receptors in neural development". Annu ... mouse LERK-4/Ephrin-A4 (Epl4), and human LERK-6/Ephrin-A2 (EPLG6): conservation of intron/exon structure". Genomics. 47 (1): ... 2002). "Expression of ephrin-A2 in the superior colliculus and EphA5 in the retina following optic nerve section in adult rat ...

CRYSTAL STRUCTURE OF EPHRIN A2 (EPHA2) RECEPTOR PROTEIN KINASE WITH COMPOUND 1J - 5NK0 , canSARS ... CRYSTAL STRUCTURE OF EPHRIN A2 (EPHA2) RECEPTOR PROTEIN KINASE WITH COMPOUND 1J ... CRYSTAL STRUCTURE OF EPHRIN A2 (EPHA2) RECEPTOR PROTEIN KINASE WITH COMPOUND 1J ...

CRYSTAL STRUCTURE OF EPHRIN A2 (EPHA2) RECEPTOR PROTEIN KINASE WITH COMPOUND 4A - 5NKB , canSARS ... CRYSTAL STRUCTURE OF EPHRIN A2 (EPHA2) RECEPTOR PROTEIN KINASE WITH COMPOUND 4A ... CRYSTAL STRUCTURE OF EPHRIN A2 (EPHA2) RECEPTOR PROTEIN KINASE WITH COMPOUND 4A ...

Sen, S., Diercke, K., Zingler, S., Lux, C. J., and Erber, R. (2015). Compression Induces Ephrin-A2 in PDL Fibroblasts via C-Fos ...

Next-day shipping cDNA ORF clones derived from LOC100332852 ephrin-A2-like available at GenScript, starting from $99.00. ... Danio rerio ephrin-A2-like (LOC100332852), mRNA.. pcDNA3.1-C-(k)DYK or customized vector. 7-9. $174.30. $249.00. ... ephrin-A2-like. Comment. MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived ... LOC100332852 ( XM_002663727.5 ) cDNA ORF clone, Danio rerio(Zebrafish) -, XP_002663773.1 Danio rerio ephrin-A2-like ( ...

Crystal structure of the human ephrin A2 ectodomain. 3hhr. HUMAN GROWTH HORMONE AND EXTRACELLULAR DOMAIN OF ITS RECEPTOR: ... Crystal Structure of EphA2 ectodomain in complex with ephrin-A5. 3mzg. Crystal structure of a human prolactin receptor ... Epha4 ectodomain complex with ephrin a5. 4m6a. N-Terminal beta-Strand Swapping in a Consensus Derived Alternative Scaffold ... The solution structure of the second fibronectin type III domain of mouse Ephrin type-A receptor 1. ...

Crystal structure of the human ephrin A2 ectodomain. 3hhr. HUMAN GROWTH HORMONE AND EXTRACELLULAR DOMAIN OF ITS RECEPTOR: ... Crystal Structure of EphA2 ectodomain in complex with ephrin-A5. 3mzg. Crystal structure of a human prolactin receptor ... Epha4 ectodomain complex with ephrin a5. 4m6a. N-Terminal beta-Strand Swapping in a Consensus Derived Alternative Scaffold ... The solution structure of the second fibronectin type III domain of mouse Ephrin type-A receptor 1. ...

We first describe the transgenic models where ephrin-A expression has been manipulated to understand the role of these guidance ... We further describe the behavioral consequences of lacking ephrin-A guidance cues in these animal models. These studies have ... to manipulate activity in the brain to compensate for the lack of guidance cues in ephrin-knockout animal models. We describe ... the mechanisms involved in creating and refining such well-defined maps in the brain with a focus on the Eph and ephrin ...

EphA5 has been shown to bind ephrin-A5, ephrin-A1,. ephrin‑A2, ephrin-A3, and ephrin-A4 (2, 3). The extracellular domains of ... is a member of the Eph receptor family which binds members of the ephrin ligand family. There are two classes of receptors, ... ephrin type-A receptor 5; Hek7; receptor protein-tyrosine kinase HEK7; Rek7; TYRO4HEK7CEK7; tyrosine-protein kinase receptor ... The Eph/ephrin families also appear to play a role in angiogenesis (3). ...

Rac1-mediated endocytosis during ephrin-A2- and semaphorin 3A-induced growth cone collapse. J. Neurosci. ... Rac1-mediated endocytosis during ephrin-A2- and semaphorin 3A-induced growth cone collapse. J. Neurosci. ... This is in contrast to the role of Rac1 in mediating ephrin-induced growth cone collapse, where inhibition of Rac1 does not ... Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase. J. Cell Biol. ...

... ephrin A2 and ephrin A5. CBF1 controls ephrin A5 by a DNA binding-dependent mechanism, ephrin A2 by a DNA binding-independent ... ephrin-A2 and ephrin-A5, in the tectum. The distribution of these two ephrins in other retinorecipient structures in the chick ... topographic mapping is impaired in muscles of mutant mice lacking ephrin-A2 plus ephrin-A5. Thus, ephrins mediate or modulate ... A prediction of this model is that in the ephrin-A2-/-; ephrin-A5-/- double mutant, axons would tend to map more posteriorly ...

EPH receptor A2 (ephrin type-A receptor 2) is a protein encoded by the EPHA2 gene and belongs to the ephrin receptor subfamily ... G. J. Szebeni, Á. Balázs, I. Madarász et al., "Achiral Mannich-base curcumin analogs induce unfolded protein response and ... cytosolic phospholipase A2, inhibitor of NF-κB kinase-1-2, P38MAPK, p-Tau (p-τ), and TNFα. ...

... ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the ...

Accelerated experience-dependent pruning of cortical synapses in ephrin-A2 knockout mice. Neuron. 80(1):64-71. ...

Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry. Zhang, H., Li, Y., Wang, H. B., Zhang, A., Chen ...

EPH A2 [591-976] Ephrin receptor A2 NM_004431 Human 50 EPH A4 [570 - 986] Ephrin receptor A4 NM_004438 Human 50 ... CDK2 [2 - 298] / Cyclin A2 [171 - 432] cyclin-dependent kinase 2-cyclin A complex NM_001798 Human 20 ...

Ephrin-A2 Un-Glus the Synapse. Postnatal maturation of the brain requires pruning of excess synapses, a process that is ... Accelerated experience-dependent pruning of cortical synapses in ephrin-A2 knockout mice ... found that Ephrin-A contributed to synapse stabilization in the cortex. ... (by Jason Berndt in Science Signaling) ...

ephrin A2 [Source:HGNC Symbol;Acc:HGNC.... EGF. 1950. EGF. epidermal growth factor [Source:HGNC S.... ...

Expression and purification of the intact cytoplasmic domain of the human ephrin receptor A2 tyrosine kinase in Escherichia ... Expression of EphA2 and Ephrin A-1 in carcinoma of the urinary bladder. Abraham, S., Knapp, D. W., Cheng, L., Snyder, P. W., ...

... distal dendritic domains of Purkinje cells were not affected by treatment with tetrodotoxin alone or in combination with ephrin ... McClelland AC, Sheffler-Collins SI, Kayser MS, Dalva MB (2009) Ephrin-B1 and ephrin-B2 mediate EphB-dependent presynaptic ... 2007) EphA4-dependent axon guidance is mediated by the RacGAP a2-chimaerin. Neuron 55: 756-767. ... The delivery of ephrinA2/Fc (C) or ephrinB1/Fc does not affect the morphology of the Purkinje cell proximal dendritic domain, ...

Catalytic domain of the Protein Tyrosine Kinase, Ephrin Receptor A2. Protein Tyrosine Kinase (PTK) family; Ephrin Receptor ( ... Binding of the ephrin ligand to EphR requires cell-cell contact since both are anchored to the plasma membrane. The resulting ... EphRs contain an ephrin binding domain and two fibronectin repeats extracellularly, a transmembrane segment, and a cytoplasmic ... There are ten vertebrate EphA receptors (EphA1-10), which display promiscuous interactions with six ephrin-A ligands. ...

Effect of Trp112Cys mutation on Ephrin A2 (33-173 amino acids) structure. Within the Ephrin family, only one mutation Ephrin A2 ... However, the number in ephrin was much more diverse, with 28.9% of mutations predicted to be pathogenic in Ephrin A2 whereas ... Unlike Ephrin A2, all the EphA were simulated till 200 ns as they attained stability post 100 ns of simulations. Slight ... A) Ephrin A2 receptor binding domain Trp112Cys. (B) EphA3 ligand binding domain Phe152Ser. (C) EphA3 kinase domain Ala749Asp. ( ...

EPHA2; EPH receptor A2; ECK, EphA2; ephrin type-A receptor 2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; ... The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their ... affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in ... This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have ...

Ephrin receptor a2 is an epithelial cell receptor for epstein-barr virus entry. Nat. Microbiol. 2018. [Google Scholar] [ ... Chen, J.; Sathiyamoorthy, K.; Zhang, X.; Schaller, S.; Perez White, B.E.; Jardetzky, T.S.; Longnecker, R. Ephrin receptor a2 is ... ephrin receptor A2 role in EBV entry into epithelial cells [70,71], and the roles of IL-1 Receptor Associated Kinase 4 (IRAK4 ...

in a majority of mice lacking (−/−) ephrin-A2 (57%), and Volasertib molecular weight ephrin-A2 and -A5 (89%). A similar but ... Fluorescent tracers were injected into V1 of wild-type (WT), ephrin-A2−/− or ephrin-A2A5−/− mice. We examined the number, ... of ephrin-A2A5−/− mice. Abnormalities in one or other of the projections were detected in 10% of ephrin-A2−/− mice. Importantly ... Compared with WT and ephrin-A2−/− mice, the volume of individual TZs in the SC was smaller ...

Ephrin receptor A2 (EphA2) plays dual functions in tumorigenesis through ligand-independent tumor promotion or ligand-dependent ...

The tyrosine kinase receptor ephrin receptor A2 (EPHA2) is overexpressed in lung (LSCC) and head and neck (HNSCC) squamous cell ... We analyzed the expression profile and mutational status of the ephrin receptor A2 (EPHA2) in SCC and MPM cell lines and ...

Abstract 750: Nanoliposomal targeting of Ephrin receptor A2 (EphA2): Clinical translation Walid S. Kamoun, Shinji Oyama, Tad ... Abstract 871: Nanoliposomal targeting of ephrin receptor A2 (EphA2): Preclinical in vitro and in vivo rationale ... View article titled, Abstract 871: Nanoliposomal targeting of ephrin receptor A2 (EphA2): Preclinical in vitro and in vivo ... View article titled, Abstract 750: Nanoliposomal targeting of Ephrin receptor A2 (EphA2): Clinical translation ...

The impact of Ephrin Receptor A2 polymorphisms on KSHV infectivity and Kaposis Sarcoma incidence and severity in HIV/AIDS ... The impact of Ephrin Receptor A2 polymorphisms on KSHV infectivity and Kaposis Sarcoma incidence and severity in HIV/AIDS ...

Vγ9Vδ2 T cells can also recognize the cell stress-induced annexin A2 and ephrin receptor A2 (EphA2) through γδ TCRs [33]. Cells ...