*  NIOSHTIC-2 Publications Search - 00188654 - The role of enzyme induction on metabolite formation of bis(2- methoxyethyl) ether...
The effect of enzyme induction on the metabolism of bis(2- methoxyethyl)ether (111966) (diglyme) was studied in rats. Male ... The effect of enzyme induction on the metabolism of bis(2- methoxyethyl)ether (111966) (diglyme) was studied in rats. Male ... The role of enzyme induction on metabolite formation of bis(2- methoxyethyl) ether in the rat.. ... NIOSH-Author; Organic-solvents; Glycols; In-vivo-studies; Laboratory-animals; Biotransformation; Enzyme-activity; Urinalysis; ...
  https://www.cdc.gov/niosh/nioshtic-2/00188654.html
*  Enzyme induction and inhibition - Wikipedia
Enzyme inhibition can refer to the inhibition of the expression of the enzyme by another molecule interference at the enzyme- ... Enzyme induction is a process in which a molecule (e.g. a drug) induces (i.e. initiates or enhances) the expression of an ... If the molecule induces enzymes that are responsible for its own metabolism, this is called auto-induction (or auto-inhibition ... the French molecular biologists François Jacob and Jacques Monod became the first to explain enzyme induction, in the context ...
  https://en.wikipedia.org/wiki/Enzyme_induction_and_inhibition
*  Nerve growth factor-mediated enzyme induction in primary cultures of bovine adrenal chromaffin cells: specificity and level of...
As compared to NGF, cAMP produces a different pattern of enzyme induction (in addition to TH, DBH, PNMT, and AChE, dopa ... These data suggest that there may be multiple mechanisms by which NGF regulates enzyme induction. We have also compared the ... In this study, we have shown that NGF mediates the specific induction of the key enzymes in catecholamine biosynthesis, ... Nerve growth factor-mediated enzyme induction in primary cultures of bovine adrenal chromaffin cells: specificity and level of ...
  http://www.jneurosci.org/content/4/7/1771
*  Pharmacodynamics of enzyme induction attributable to carbamazepine treatment using midazolam, caffeine and digoxin as probe...
Enzyme induction is a process whereby a molecule enhances the expression of enzymes. If the affected enzymes are involved in ... The aim of the conducted research was to investigate these key aspects of enzyme induction and the consequences that induction ... The key aspects of the enzyme induction process have been examined using mechanistic induction models. These novel models ... The induction process depends on the half-life of the induced enzyme, the pharmacokinetics of the inducing agent, and the ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:170066
*  Coordinate Protein Kinase Activation and Specific Enzyme Induction by Cyclic Nucleotide Derivatives in Intact Cultured Hepatoma...
The results demonstrate that enzyme induction is tightly coupled to protein kinase activation and is consistent with the ... Coordinate Protein Kinase Activation and Specific Enzyme Induction by Cyclic Nucleotide Derivatives in Intact Cultured Hepatoma ... Coordinate Protein Kinase Activation and Specific Enzyme Induction by Cyclic Nucleotide Derivatives in Intact Cultured Hepatoma ... Coordinate Protein Kinase Activation and Specific Enzyme Induction by Cyclic Nucleotide Derivatives in Intact Cultured Hepatoma ...
  http://molpharm.aspetjournals.org/content/16/2/449
*  Barbiturate enzyme induction
Home / ABA Keyword Categories / B / Barbiturate enzyme induction. Barbiturate enzyme induction. Definition. Barbiturates ( ... This enzyme induction also causes barbiturate tolerance due increased barbiturate metabolism. In addition, barbiturates induce ... Chronic use of barbiturates will cause upregulation, or induction, of the microsomal enzymes (CYPs 1A2, 2C9, 2C19, and 3A4), ... is their effect on the hepatic microsomal enzyme system (cytochrome P450 (CYP) enzymes). These effects are dependent on the ...
  http://www.openanesthesia.org/aba_barbiturate_enzyme_induction/
*  Tegretol Enzyme Induction
... enzymeCarbamazepine 79 4.5. Enzyme induction and inhibition 73 The effects of enzyme induction and enzyme inhi- Proliferation ... enzymeCarbamazepine 79 4.5. Enzyme induction and inhibition 73 The effects of enzyme induction and enzyme inhi- Proliferation ... Concurrent Enzyme Induction with Carbamazepine tion of enzyme induction have emerged over the Selective liver enzyme induction ... Induction/?a=sLearn what other patients are saying about Phenytoin and Enzyme Induction.ENZYME INDUCTION AND INHIBITION - ...
  http://observatoriojyd.org/index.php?option=com_k2&view=itemlist&task=user&id=73635
*  Variations of some parameters of enzyme induction in chemical workers. | IRIS Università degli Studi di Firenze
... some enzyme being inhibited and others induced in the same group of workers. The sensitivity of these workers to toxic effects ... some enzyme being inhibited and others induced in the same group of workers. The sensitivity of these workers to toxic effects ...
  https://flore.unifi.it/handle/2158/329003
*  Investigations on Cell Proliferation and Enzyme Induction in Male Rat Kidney and Female Mouse Liver Caused by Tetrahydrofuran :...
It is concluded that THF enhances tumor formation in male rat kidney and female mouse liver via induction of cell proliferation ...
  http://oxfordindex.oup.com/view/10.1093/toxsci/70.1.140
*  A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing...
A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing ... Drug Interaction Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and ... The purpose of this study is to evaluate the potential effects of an intravenous (IV) induction and subcutaneous (SC) ... enzymes (CYP3A4, CYP2C9, CYP2C19, CYP2D6, and CYP1A2) in participants with moderate to severe Crohn's disease (CD). ...
  https://clinicaltrials.gov/ct2/show/NCT03358706?term=omeprazole&
*  KAKEN - Research Projects | Induction of enzymes by light in the mycelium of wood decay fungi (KAKENHI-PROJECT-02660181)
Light / Aeration condition / Tyromyces palustris / Coriolus versicolor / Enzyme induction / Mass loss / Hydrolytic enzyme / ... Induction of enzymes by light in the mycelium of wood decay fungi. Research Project ... Effects of light and aeration conditions on the activities of hydrolytic enzymes' Mokuzai Gakkaishi.. *. Description. 「研究成果報告書概 ... Effects of light and aeration condition on the activities of hydrolytic enzymes in the T. palustris mycelium. (1) When the ...
  https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02660181/
*  In Vitro Inhibition and Induction of Human Hepatic Cytochrome P450 Enzymes by Modafinil | Drug Metabolism & Disposition
In Vitro Inhibition and Induction of Human Hepatic Cytochrome P450 Enzymes by Modafinil. Philmore Robertson, Heleen H. DeCory, ... In Vitro Inhibition and Induction of Human Hepatic Cytochrome P450 Enzymes by Modafinil. Philmore Robertson, Heleen H. DeCory, ... In Vitro Inhibition and Induction of Human Hepatic Cytochrome P450 Enzymes by Modafinil. Philmore Robertson, Heleen H. DeCory, ... Enzyme Induction.. Freshly isolated human hepatocytes were cultured according to the method described by LeCluyse et al. (1994 ...
  http://dmd.aspetjournals.org/content/28/6/664.long
*  Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants | Drug...
Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants. Kouichi ... Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants. Kouichi ... Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants. Kouichi ... Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants ...
  http://dmd.aspetjournals.org/content/early/2006/03/31/dmd.105.007286
*  DailyMed - SERTRALINE- sertraline hydrochloride tablet, film coated
Microsomal Enzyme Induction Preclinical studies have shown sertraline to induce hepatic microsomal enzymes. In clinical studies ... These hepatic enzyme elevations usually occurred within the first 1 to 9 weeks of drug treatment and promptly diminished upon ... Induction of emesis is not recommended. Gastric lavage with a large-bore orogastric tube with appropriate airway protection, if ... elevated enzymes, increased bilirubin, hepatomegaly, hepatitis, jaundice, abdominal pain, vomiting, liver failure and death. ...
  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f9641190-9151-4f7e-89ff-1e7a818c30ee
*  Induction of Drug Metabolism Enzymes and MDR1 Using a Novel Human Hepatocyte Cell Line | Journal of Pharmacology and...
Measurement of induction by cytochromes 450 enzyme activity. Induction of CYP3A4, CYP2C9, and CYP1A2 enzyme activity in Fa2N-4 ... Induction of Drug Metabolism Enzymes and MDR1 Using a Novel Human Hepatocyte Cell Line. Jessica B. Mills, Kelly A. Rose, Nalini ... Induction of Drug Metabolism Enzymes and MDR1 Using a Novel Human Hepatocyte Cell Line. Jessica B. Mills, Kelly A. Rose, Nalini ... Induction of Drug Metabolism Enzymes and MDR1 Using a Novel Human Hepatocyte Cell Line. Jessica B. Mills, Kelly A. Rose, Nalini ...
  http://jpet.aspetjournals.org/content/309/1/303
*  Activity of antioxidant enzymes during induction of morphogenesis of Fritillaria meleagris in bulb scale culture
Activity of antioxidant enzymes during induction of morphogenesis of Fritillaria meleagris in bulb scale culture. 2014. ... Enzyme activity was measured 7, 14, 21, and 28 days after the start of morphogenesis induction. Superoxide dismutase and ... We investigated the activity of 3 antioxidant enzymes: superoxide dismutase, catalase, and peroxidase during morphogenesis of ...
  http://ibiss-r.rcub.bg.ac.rs/handle/123456789/2292
*  Stimulation of AMP-Activated Protein Kinase Is Essential for the Induction of Drug Metabolizing Enzymes by Phenobarbital in...
Induction of drug-metabolizing enzymes and drug transporters by drugs and other chemicals is an adaptive response of mammals ... Stimulation of AMP-Activated Protein Kinase Is Essential for the Induction of Drug Metabolizing Enzymes by Phenobarbital in ... Stimulation of AMP-Activated Protein Kinase Is Essential for the Induction of Drug Metabolizing Enzymes by Phenobarbital in ... Stimulation of AMP-Activated Protein Kinase Is Essential for the Induction of Drug Metabolizing Enzymes by Phenobarbital in ...
  http://molpharm.aspetjournals.org/content/70/6/1925
*  Enzyme repression or induction acts at the level of - Medical Association of the USA
Enzyme repression or induction acts at the level of. By admin , 26.12.2017 ... Category: benefit blood coenzyme enzyme health sleep Post navigation. ← Digestive enzymes to help with gluten intoleranceHow do ... Studies suggest that the human sirtuins may function as intracellular regulatory enzyme repression or induction acts at the ... 1 is used to denote the gene product most similar to yeast Sir2 in what class of enzyme is present in beano and activity. In ...
  http://russky.me/enzyme-repression-or-induction-acts-at-the-level-of/
*  Biochemistry Enzymes and Biomarkers Flashcards by tish bullman | Brainscape
Study Biochemistry Enzymes and Biomarkers flashcards from tish bullman ... Biochemistry Enzymes and Biomarkers Flashcards Preview Cardio , Biochemistry Enzymes and Biomarkers , Flashcards ... Enzymes of similar catalytic activity but structural differences, pattern may be helpful to localize origin, e.g. CK, ALP. e.g ... Enzyme induction. Structural damage - cholestasis e.g. alcoholic cirrhosis. 25 γGT is elevated in ...
  https://www.brainscape.com/flashcards/biochemistry-enzymes-and-biomarkers-3056880/packs/3621475
*  ADME Services
Enzyme Induction and Inhibition Enzyme Induction and Inhibition Contact Us Most drug-drug interactions are metabolism based and ... Enzyme induction and inhibition, including cytochrome P450 (CYP) induction services using both cryopreserved and fresh human ... CYP Induction CYP Induction Contact Us Services include evaluation of drug-transporter interactions using in vitro models ... We can identify metabolic pathways catalyzed by multiple enzymes, including CYPs, FMOs, UGTs, CES enzymes, among others, to ...
  http://www.corning.com/emea/de/products/life-sciences/support-main/services/adme-services.html
*  c1. BASIC SCIence C (155-226) Flashcards by harold robinson | Brainscape
c. enzyme induction. Phenobarbitol is one of the most potent enzyme inducing agents. Patients who take phenobarbitol have an ... a. slow induction, rapid emergence. b. slow induction, slow emergence. c. rapid induction, slow emergence. d. rapid induction, ... b. rapid sequence induction with cricoid pressure. c. avoid nitrous oxide. d. insertion of nasogastric tube before induction ... The enzyme tyrosine hydroxylase is the rate limiting enzyme in catecholamine synthesis. It catalyzes the step from tyrosine to ...
  https://www.brainscape.com/flashcards/c1-basic-science-c-155-226-1828717/packs/3173451
*  Lamictal XR (Lamotrigine Extended-Release Tablets): Side Effects, Interactions, Warning, Dosage & Uses
Enzyme Induction. The effects of lamotrigine on the induction of specific families of mixed-function oxidase isozymes have not ... Enzyme-inducing antiepileptic drugsa. 0.79 (0.69, 0.90). 0.71 (0.61, 0.82). 0.99 (0.89, 1.09). ... Inhibition of this enzyme may interfere with the biosynthesis of nucleic acids and proteins. When oral daily doses of ... Antiepileptic drugs other than enzyme-inducing antiepileptic drugsa or valproate. 1.00 (0.88, 1.14). 0.89. (0.78, 1.03). 1.14. ...
  https://www.rxlist.com/lamictal-xr-drug.htm
*  Metabolism
... recombinant metabolic enzymes to primary hepatocytes. ... Enzyme induction. *Drug clearance *Metabolite ID. *Hepatic ...
  https://www.corning.com/kr/ko/products/life-sciences/products/adme-tox-research/metabolism.html
*  These highlights do not include all the information needed to use Lamotrigine tablets safely and effectively. See full...
Enzyme Induction: The effects of Lamotrigine on the induction of specific families of mixed-function oxidase isozymes have not ... Inhibition of this enzyme may interfere with the biosynthesis of nucleic acids and proteins. When oral daily doses of ... that self-induction by Lamotrigine may not occur when Lamotrigine is given as adjunctive therapy in patients receiving enzyme- ... Folate Metabolism: In vitro, lamotrigine inhibited dihydrofolate reductase, the enzyme that catalyzes the reduction of ...
  https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d33c4293-347c-49a1-9d98-f291c3dab6da&type=display
*  Microbial Biochemistry | Georges N. Cohen | Springer
Enzyme Induction in Catabolic Systems. Cohen, G. N.. Pages 179-193 Preview Buy Chapter $29.95 ...
  http://www.springer.com/us/book/9789401789073