Enterochromaffin (EC) cells (also known as Kulchitsky cells) are a type of enteroendocrine cell, and neuroendocrine cell. They ... Enterochromaffin-like (ECL) cells are a population of cells that are found in the gastric pits of the stomach luminal ... 1985). "Ultrastructure of enterochromaffin cells and associated neural and vascular elements in the mouse duodenum". Cell and ... ECL cells histologically appear similar to EC cells and are hence named as such. They are however a different cell type and do ...
"Enterochromaffin-like Cells" by people in this website by year, and whether "Enterochromaffin-like Cells" was a major or minor ... "Enterochromaffin-like Cells" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Neuroendocrine cells in the glands of the GASTRIC MUCOSA. They produce HISTAMINE and peptides such as CHROMOGRANINS. ECL cells ... Below are the most recent publications written about "Enterochromaffin-like Cells" by people in Profiles. ...
Lansoprazole produced dose-related gastric enterochromaffin-like (ECL) cell hyperplasia and ECL cell carcinoids in both male ... Enterochromaffin-like (ECL) Cell Effects. During lifetime exposure of rats with up to 150 mg/kg/day of lansoprazole dosed seven ... Because this enzyme system is regarded as the acid (proton) pump within the parietal cell, lansoprazole has been characterized ... In male rats, lansoprazole produced a dose-related increase of testicular interstitial cell adenomas. The incidence of these ...
Serotonin synthesis by enterochromaffin (EC) cells is influenced by the gut microbiota and has been reported to have an ... The number of EC cells in the caecum of IBS-D patients was higher than in HCs and the expression of TPH1 was higher in IBS-D ... EC cell numbers increased in IBS-D patients and the expression of TPH1 was higher than in HCs. The Ruminococcus torques group ... The abundance of Dorea was positively associated with EC cell number, IBS-SSS, HAM-A, HAM-D and frequency of abdominal pain. ...
Enterochromaffin-like (ECL) Cell Effects. There are no data available on the effects of intravenous esomeprazole on ECL cells. ... Increased gastrin causes enterochromaffin-like cell hyperplasia and increased serum Chromogranin A (CgA) levels. The increased ... The incidence of ECL cell hyperplasia in these studies increased with time; however, no case of ECL cell carcinoids, dysplasia ... the prevalence of ECL cell hyperplasia increased with time and dose. No patient developed ECL cell carcinoids, dysplasia, or ...
Enterochromaffin-like (ECL) Cell Effects Human gastric biopsy specimens have been obtained from more than 3000 patients treated ... Increased gastrin causes enterochromaffin-like cell hyperplasia and increased serum Chromogranin A (CgA) levels. The increased ... Lupus erythematosus is an autoimmune disorder (the bodys immune cells attack other cells or organs in the body). Some people ... The incidence of ECL cell hyperplasia in these studies increased with time; however, no case of ECL cell carcinoids, dysplasia ...
Enteroendocrine cell physiology, specifically enterochromaffin cell mechanosensitivity. Mayo Clinic locations. Rochester, ... C-Sig Mini Sabbatical AwardMayo Clinic Center for Cell Signaling in Gastroenterology ...
Prinz C, Zanner R, Gratzl M. Physiology of gastric enterochromaffin-like cells. Annu Rev Physiol. 2003. 65:371-82. [QxMD ... Neuroendocrine tumor markers and enterochromaffin-like cell hyper/dysplasia in type 1 diabetes. Diabetes Care. 2004 Jun. 27(6): ... Parietal cells are responsible for the secretion of hydrochloric acid and also produce intrinsic factor. Parietal cells have ... Loss of parietal cell expression of Sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells. ...
5-HT (magenta) labels enterochromaffin cells in colonic tissues, showing no co-expression of DTR-GFP (cyan). Scale bars ... a, Single cell RNA-seq analysis of FZD1, 2, and 7 expression in different cell types within colonic tissues in mice58. Size of ... DsRed-positive cells are clearly separate from lymphatic endothelial cells. Scale bar is 50 µm. c-f, Experiments were carried ... Natural killer cells degenerate intact sensory afferents following nerve injury. Cell 176, 716-728.e18 (2019). ...
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways. Cell 2017, 170, 185-198.e116. [Google ... Braun, T.; Voland, P.; Kunz, L.; Prinz, C.; Gratzl, M. Enterochromaffin cells of the human gut: Sensors for spices and odorants ... Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis. PLoS ONE ... Cell. Mol. Life Sci. 2015, 72, 217-236. [Google Scholar] [CrossRef]. *Lee, R.J.; Kofonow, J.M.; Rosen, P.L.; Siebert, A.P.; ...
Inflammatory mediators participate in controlling the activity of enterochromaffin cells that store and release chromograni … ... Inflammatory mediators participate in controlling the activity of enterochromaffin cells that store and release chromogranins. ...
Direct effects of nitric oxide on histamine release from rat enterochromaffin-like cells. Eur. J. Pharmacol 2006, 535, 25-33. [ ... Cell. Cardiol. 1999, 31, 827-836. [Google Scholar]. *Pacher, P.; Beckman, J.S.; Liaudet, L. Nitric oxide and peroxynitrite in ... Our data refers to Chen et al. [51] who observed that cultured dorsal root ganglia neural cells co-incubated with ADMA ... The excessive generation of reactive oxygen species (ROS), adhesion of neutrophils to endothelial cells, the activation of ...
It is found in enterochromaffin cells in the gastrointestinal tract, where it regulates intestinal smooth muscle function, and ... These neoplasms primarily arise from enterochromaffin cells of endocrine and nervous system origin; the great majority of the ... mast cells, extracellular matrix (collagen, myxoid matrix, and elastin), and an overlying endothelial layer. Over 95% of those ... Serotonin receptors are present on heart valves and participate in collagen synthesis in valvular interstitial cells [16, 17]. ...
of the bodys total serotonin resides in the enterochromaffin cells in the gut, where it helps regulate the movement of the ... 2015). Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells ...
There are many types of cells in the stomach that help with the digestion of food. Here are their names, functions, and ... 2018). A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into ... These cells exist mainly in the fundus of the stomach.. *D-cells: These cells are in the pylorus of the stomach. They secrete ... ECL-like cells: These cells secrete histamine when gastrin stimulates them. Histamine binds to receptors on the parietal cells ...
Histamine is the most important gastric acid secretion stimulant and is released from enterochromaffin-like cells by gastric ... Oxidative phosphorylation dependent secretion by parietal cells. * Parietal cells: found in mucosal glands of the body and ... Activation of postganglionic vagal fibers (muscarinic cholinergic parietal cells receptor activation). * Role of histamine: * ... Basolateral parietal cells membranes contain receptors for: * Histamine-- stimulation gastric acid secretion ...
Debnath, S., and Guha, D. (2007). Role of Moringa oleifera on enterochromaffin cell count and serotonin content of experimental ... The extract protected against ulcer formation in aspirin-induced rats by stimulating enterochromaffin cells in the ... 2013). Antioxidant extracts of African medicinal plants induce cell cycle arrest and differentiation in B16F10 melanoma cells. ... cancerous cell death (Gismondi et al., 2013). It caused apoptosis at the sub G1-area and induced cell arrest at the G2/M phase ...
Adenosine A1 receptor activation inhibits histamine release in gastric enterochromaffin-like cells ... We found that MafF decreased in HCC tissues and cells. Lentivirus-mediated MafF overexpression inhibited HCC cell proliferation ... Effect of RBM10 on regulating the proliferation and metastasis activity of human hepatocellular carcinoma cells by affecting ... and induced cell apoptosis. Bioinformatics analysis and luciferase assay identified MafF as a direct target of miR-224-5p. RNA ...
Adenosine A1 receptor activation inhibits histamine release in gastric enterochromaffin-like cells ...
Interaction of Human Enterochromaffin Cells with Human Enteric Adenovirus 41 Leads to Serotonin Release and Subsequent ... Fiber mediated receptor masking in non-infected bystander cells restricts adenovirus cell killing effect but promotes ... Detta är ett kritiskt steg som ofta (men inte alltid) avgör vilken typ av cell, vävnad eller organ som infekteras. Detta steg ... Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection ...
... or by signaling from enterochromaffin cells; nerve endings in the submucosal or the myenteric plexus are typically activated by ... Reichling, D. B., Green, P. G., and Levine, J. D. (2013). The fundamental unit of pain is the cell. Pain 154(Suppl. 1), S2-S9. ... In the GI tract, nociceptive neurons, with cell bodies in the dorsal root ganglion (DRG), have free nerve endings that ... Typically, the peripheral nociceptive neuron synapses on a cell body of a projection neuron within the superficial lamina of ...
High gastrin levels also cause growth of other cells called enterochromaffin-like (ECL) cells, which are important in signaling ... Increased ECL cell density might also contribute to rebound gastric hyperacidity.. To determine if gastrin levels and ECL cells ... ECL cell density did not increase during or after treatment, suggesting these important signaling cells also do not contribute ... They measured ECL cell density by assessing serum chromogranin A (CgA) levels. ...
Circulating gastrin triggers the release of histamine from enterochromaffin-like cells in the body of the stomach. Histamine ... The parietal cells secrete acid, and the resulting drop in pH causes the antral D cells to release somatostatin, which inhibits ... Epithelial cells remove excess hydrogen ions (H+) via membrane transport systems and have tight junctions, which prevent back ... Acid is secreted by parietal cells in the proximal two thirds (body) of the stomach. Gastric acid aids digestion by creating ...
CONTEXT: Gastric neuroendocrine tumors are rare neoplasms that originate from gastric enterochromaffin-like (ECL) cells in the ... CONTEXT: Gastric neuroendocrine tumors are rare neoplasms that originate from gastric enterochromaffin-like (ECL) cells in the ... Carcinogenic hypergastrinemia: signet-ring cell carcinoma in a patient with multiple endocrine neoplasia type 1 with Zollinger- ... RESULTS: Immunohistochemical studies of gastric ECL cell tumors showed a largely diminished E-cadherin expression in comparison ...
Gut enterochromaffin cells drive visceral pain and anxiety. Nature. 2023 Apr; 616(7955):137-142. Bayrer JR, Castro J, ...
However, cytotoxic chemotherapy appears to be associated with release of serotonin from the enterochromaffin cells of the small ...
Neuroendocrine tumor of the rectum is a rare epithelial tumor of rectum arising from enterochromaffin cells, most often in the ...
Neuroendocrine tumors (NETs) are rare tumors originating from enterochromaffin cells of the neuroendocrine system of the ... Due to the presence of a variety of cells producing different hormones, the gastrointestinal tract may be considered the ... Depending upon the specific production of peptides and amines produced by the different neuroendocrine cell types, along with ...
In 1914, Gosset and Masson demonstrated that carcinoid tumors might arise from enterochromaffin cells (Kulchitsky cells) within ... Erspamer V, Asero B. Identification of enteramine, the specific hormone of the enterochromaffin cell system, as 5- ... arising in normal-appearing mucosa from enterochromaffin-like cells in the gastric fundus. These tumors are generally located ... 1, 2, 3] Carcinoid tumors are of neuroendocrine origin and derive from primitive stem cells, which can give rise to multiple ...
... of chronic inflammatory changes in the gut mucosa after an infection and the persistence of the enterochromaffin cell ... The baculovirus-insect cell expression system-insect cells used in conjunction with the baculovirus expression vector system ( ... Killer T cells in older adults found to be less effective at fighting influenza viruses ... Innovations in baculovirus-insect cell expression systems. Dr. Yingmin Zhu, Dr. Amy Sheng and Dr. Xuejiao Zhang ...