Enoximone - Wikipedia
Enoximone (INN, trade name Perfan) is an imidazole phosphodiesterase inhibitor. It is used in the treatment of congestive heart ... Media related to Enoximone at Wikimedia Commons v t e (Articles with short description, Short description matches Wikidata, ... "Combined use of ultra-short acting beta-blocker esmolol and intravenous phosphodiesterase 3 inhibitor enoximone". Expert Opin ...
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... higher with enoximone (32%) than with placebo (22%). During therapy, five deaths occurred in the enoximone group, and none ... 1.7 ml O2/kg/min with enoximone and 0.2 +/- 1.5 ml O2/kg/min with placebo). The dropout rate was significantly higher (p less ... 50 receiving enoximone and 52 receiving placebo) with moderate to moderately severe congestive heart failure. All were on a ... in anaerobic threshold at 1 month with enoximone. (2.7 +/- 0.8 ml O2/kg/min) compared with placebo (-0.8 +/- 1.2 ml O2/kg/min ...
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25) SANDRONI C, CAVALLARO F, ADDARIO C, FERRO G, GALLIZZI F, A NTONELLI M. Successful treatment with enoximone for severe ... 242 Ca++ Calcium channel ENOXIMONE Activation - Phosphodiesterase Cyclic AMP Metabolites ATP GLUCAGON Adenilate cyclase + ... Phosphodiesterase Inhibitors Phosphodiesterase III inhibitors (enoximone) represent possible alternatives to glucagon in CCB ... Activated Adenilate cyclase Beta adrenoceptor Catecholamines Figure 1. Mechanisms of action of glucagon and enoximone. ...
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