IKK\(\beta\) Regulates Essential Functions of the Vascular Endothelium Through Kinase-Dependent and -Independent Pathways
Vascular endothelium provides a selective barrier between the blood and tissues, participates in wound healing and angiogenesis ... IKK\(\beta\) -deleted endothelium manifests increased vascular permeability and reduced migration. Surprisingly, we find that ... IKK\(\beta\) Regulates Essential Functions of the Vascular Endothelium Through Kinase-Dependent and -Independent Pathways. ... IKK\(\beta\) Regulates Essential Functions of the Vascular Endothelium Through Kinase-Dependent and -Independent Pathways. ...https://dash.harvard.edu/handle/1/8316402
AMPK Alpha 1-Induced RhoA Phosphorylation Mediates Vasoprotective Effect of Estradiol | Arteriosclerosis, Thrombosis, and...
... estradiol-mediated vascular protection could also involve direct effect on vascular smooth muscle. In this context, inhibition ... Goirand et al observed that activation AMPKα1, but not AMPKα2, induced aortic relaxation in mice in an endothelium- and eNOS- ... A, Vascular smooth muscle cells (VSMC) were treated with estradiol (E2) at a concentration of 10−9 mol/L for 1 hour without ( ... Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta. Science. 2002;295:505-508. ...http://atvb.ahajournals.org/content/31/11/2634
Vascular Function Tests in Women With no Obstructive CAD | JACC: Cardiovascular Imaging
Endothelium plays a critical role in maintaining healthy homeostatic properties of the vasculature. Endothelial dysfunction ... This study underlines the importance of assessing vascular functions in more than one vascular bed and the need to define which ... Vascular Function Tests in Women With no Obstructive CAD Message Subject (Your Name) has forwarded a page to you from JACC: ... Vascular wall imaging by intravascular ultrasonography or coronary computerized tomography angiography are also viable options ...http://imaging.onlinejacc.org/content/9/4/418
Impaired Progenitor Cell Activity in Age-Related Endothelial Dysfunction | JACC: Journal of the American College of Cardiology
Elderly individuals showed endothelium-specific dysfunction of vascular reactivity, indicated by impaired FMD with preserved ... EPC function correlates with endothelium-dependent vascular parameters. We showed a strong univariate correlation between the ... or both could produce disequilibrium between vascular injury and vascular repair, which leads to atherosclerosis (2,33). Indeed ... This kind of vascular repair mechanism is critical for maintaining organ viability in a setting of impaired blood flow or ...http://www.onlinejacc.org/content/45/9/1441
Interleukin-33 Drives a Proinflammatory Endothelial Activation That Selectively Targets Nonquiescent Cells | Arteriosclerosis,...
To more directly address the effect of cytokines on the vascular endothelium, we enumerated the fraction of vessels that ... We therefore considered that if nuclear IL-33 were involved in the control of vascular integrity and quiescence,27 it might ... Arteriosclerosis, Thrombosis, and Vascular Biology. 2013;33:e47-e55, originally published January 16, 2013 ... Arteriosclerosis, Thrombosis, and Vascular Biology. 2013;33:e47-e55, originally published January 16, 2013 ...http://atvb.ahajournals.org/content/33/2/e47
Predictive value of noninvasivelydetermined endothelial dysfunction for long-term cardiovascular events inpatients with...
The vascular endothelium plays a central role in the regulation of vascular tone, thrombosis, and inflammation through ... 1990) Regulatory functions of the vascular endothelium. N Engl J Med 323:27-36. ... Consecutive patients with peripheral vascular disease undergoing nonemergent vascular surgery at Boston Medical Center and the ... 1998) Endothelium-dependent flow-mediated vasodilation in coronary and brachial arteries in suspected coronary artery disease. ...http://www.onlinejacc.org/content/41/10/1769
Rapid Perfusion and Network Remodeling in a Microvascular Construct After Implantation | Arteriosclerosis, Thrombosis, and...
Figure 3. Microvascular implants contain vascular endothelium and smooth muscle-positive perivascular cells that are nearly ... Vascular Biology. Rapid Perfusion and Network Remodeling in a Microvascular Construct After Implantation. Benjamin R. Shepherd ... vascular remodeling. Vascularization is the process by which perfusion pathway length and vessel segment number are increased ... Folkman J, Cotran R. Relation of vascular proliferation to tumor growth. Int Rev Exp Pathol. 1976; 16: 207-248. ...http://atvb.ahajournals.org/content/24/5/898
Endothelial Function and Dysfunction | Circulation
Endothelium in Normal Vascular Homeostasis. Although only a simple monolayer, the healthy endothelium is optimally placed and ... depends on profound dynamic changes in vascular biology.1 The endothelium has emerged as the key regulator of vascular ... Vascular endothelium, hemodynamic forces, and atherogenesis. Am J Pathol. 1999; 155: 1-5. ... The importance of the endothelium was first recognized by its effect on vascular tone. This is achieved by production and ...http://circ.ahajournals.org/content/115/10/1285
... further reducing PVAT inflammation and breaking the vicious cycle between adipose tissue and vascular endothelium. ... In normal vascular physiology, nitric oxide (NO) plays a key role in maintaining the vascular wall in a quiescent state by ... The initial trigger for the reduction in vascular NO bioavailability during obesity may involve activation of vascular nuclear ... Perivascular fat-mediated vascular dysfunction and remodeling through the AMPK/mTOR pathway in high-fat diet-induced obese rats ...http://diabetes.diabetesjournals.org/content/61/12/3070
Patente US5302384 - Endothelial-derived II-8 adhesion inhibitor - Google Patentes
The adherence of leukocytes to vascular endothelium in areas of inflammation and injury has long been known. It has also long ... 136:4548-4553 (1986)) can act directly on vascular endothelium in vitro to increase the adhesiveness of the endothelial cell ... Bevilacqua et al., "Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear ... Bevilacqua et al., "Interleukin-1 activation of vascular endothelium-effects on procoagulant activity and leukocyte adhesion", ...http://www.google.es/patents/US5302384?dq=flatulence
British Library EThOS: The role of the vascular endothelium in experimental and genetic hypertension
Endothelial modulation was similar in both sets of arteries, suggesting that the endothelium does not mask an increased ... There was a positive correlation between blood pressure and vascular structure, suggesting that blood pressure is a major ... determinant of vascular structure. Only ACE inhibitor treatment normalised resistance vessel contractility and endothelium- ... Treatment also prevented the development of impaired endothelium-dependent relaxation. Treatment of SHRs with either an ACE ...http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.674367
Philip A. Marsden | Medical Biophysics, University of Toronto
Regulated expression of nitric oxide (NO) in vascular tissue. Release of NO from the vascular endothelium represents a ... Yan, M.S., Matouk, C.C., Marsden, P.A. Epigenetics of the vascular endothelium. J Appl Physiol. 109:916-926, 2010 ... The control of new blood vessel formation, or angiogenesis, is orchestrated by vascular endothelium and endothelial cells ... vascular endothelium at the post-transcriptional level. Also, our most recent identification of a VEGF-A-responsive large ...http://medbio.utoronto.ca/faculty/marsden.html
At baseline, all women underwent a vascular reactivity test on the brachial artery to measure the endothelium-dependent ... It is well known that FMD induced by reactive hyperemia is endothelium dependent (33,34); in other words, it depends on the ... Rubanyi GM, Romero JC, Vanhoutte PM: Flow-induced release of endothelium-derived relaxing factor. Am J Physiol 250:1145-1149, ... Sagach VF, Tkachenko MN: On the mechanisms of the involvement of endothelium in reactive hyperemia. Experientia 47:828-830, ...http://care.diabetesjournals.org/content/28/3/702
Leukocyte-Endothelium Interaction During the Early Stages of Hypercholesterolemia in the Rabbit | Arteriosclerosis, Thrombosis,...
Expression of P-selectin on the vascular endothelium was significantly increased in both 1- and 2-week HC diet-fed rabbits by ≈ ... Recently, other endothelial CAMs (ie, VCAM-1 and ICAM-1) have also been found to be expressed on the vascular endothelium ... Basal NO Release From the Vascular Endothelium. In an effort to determine the degree of endothelial dysfunction in large ... Endothelium-dependent vascular relaxation is abnormal in the coronary microcirculation of atherosclerotic primates. Circulation ...http://atvb.ahajournals.org/content/18/7/1093
Endothelial Function and Aminothiol Biomarkers of Oxidative Stress in Healthy Adults | Hypertension
The bioavailability of NO from the vascular endothelium is exquisitely modulated by reactive oxygen species that degrade NO, ... levels correlated with endothelium-dependent but not endothelium-independent vasodilation, even after adjusting for the ... Blood Vessels/Endothelium. Endothelial Function and Aminothiol Biomarkers of Oxidative Stress in Healthy Adults. Salman Ashfaq ... Relationship of Endothelium-Independent Vasodilation With Markers of Oxidative Stress and Traditional Risk Factors. There was a ...http://hyper.ahajournals.org/content/52/1/80
Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium
Despite its known expression in both the vascular endothelium and the lung epithelium, until recently the physiological role of ... Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium. Niaudet, Colin Uppsala University, ... Vascular BiologyDepartment of Immunology, Genetics and Pathology In the same journal. PLoS ONE On the subject. Immunology in ... Further analysis of this knockout model revealed cerebral vascular leakage, beginning at around 1.5 months of age. Additionally ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:867036
Effects of Different Types of Exercise Training Followed by Detraining on Endothelium-Dependent Dilation in Patients With...
Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. J Clin Invest. 2000; 105: ... Training improves endothelium-dependent vasodilation in resistance vessels of patients with heart failure. J Appl Physiol. 1997 ... It has been speculated that the volume of exercise could influence vascular reactivity.34 In our study, the total number of ... Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol. 2005; 561: 1-25. ...http://circ.ahajournals.org/content/119/12/1601
Antigenic Heterogeneity of Vascular Endothelium | SpringerLink
In view of the participation of vascular endothelial cells (EC) in a wide range of normal and pathological conditions, ... Antigenic Heterogeneity of Vascular Endothelium. In: Catravas J.D., Callow A.D., Gillis C.N., Ryan U.S. (eds) Vascular ... In view of the participation of vascular endothelial cells (EC) in a wide range of normal and pathological conditions, ... Endothelium. NATO ASI Series (Series A: Life Sciences), vol 208. Springer, Boston, MA. * DOI https://doi.org/10.1007/978-1-4615 ...https://link.springer.com/chapter/10.1007/978-1-4615-3736-6_51
Endothelium/Vascular Type/Nitric Oxide | Circulation
Circular Noncoding RNA HIPK3 Mediates Retinal Vascular Dysfunction in Diabetes Mellitus Kun Shan, Chang Liu, Bai-Hui Liu, Xue ...http://circ.ahajournals.org/taxonomy/term/1470
Potassium softens vascular endothelium and increases nitric oxide release | PNAS
Potassium softens vascular endothelium and increases nitric oxide release. H. Oberleithner, C. Callies, K. Kusche-Vihrog, H. ... Potassium softens vascular endothelium and increases nitric oxide release. H. Oberleithner, C. Callies, K. Kusche-Vihrog, H. ... Potassium softens vascular endothelium and increases nitric oxide release. H. Oberleithner, C. Callies, K. Kusche-Vihrog, H. ... Potassium softens vascular endothelium and increases nitric oxide release Message Subject (Your Name) has sent you a message ...http://www.pnas.org/content/106/8/2829.full
Endothelium/Vascular Type/Nitric Oxide | Stroke
Vascular Cell Senescence Contributes to Blood-Brain Barrier Breakdown Yu Yamazaki, Darren J. Baker, Masaya Tachibana, Chia-Chen ... Differential Effect of B-Vitamin Therapy by Antiplatelet Use on Risk of Recurrent Vascular Events After Stroke Baback Arshi, ...http://stroke.ahajournals.org/collection/endotheliumvascular-typenitric-oxide
Vascular Endothelium in Hemostasis and Thrombosis | Postgraduate Medical Journal
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center's RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...http://pmj.bmj.com/content/64/752/481.2
Psycho-Neuro-Immune-Endocrine System, Vascular Endothelium and Heart Failure | Clinical Science
Psycho-Neuro-Immune-Endocrine System, Vascular Endothelium and Heart Failure. L. Lorente, M.-A. Aller, J. Arias ... Psycho-Neuro-Immune-Endocrine System, Vascular Endothelium and Heart Failure Message Subject (Your Name) has forwarded a page ...http://www.clinsci.org/content/90/4/321
Vascular endothelium responds to fluid shear stress gradients. | Arteriosclerosis, Thrombosis, and Vascular Biology
Vascular endothelium responds to fluid shear stress gradients.. N DePaola, M A Gimbrone, P F Davies, C F Dewey ... In vitro investigations of the responses of vascular endothelium to fluid shear stress have typically been conducted under ... Arteriosclerosis, Thrombosis, and Vascular Biology. 1992;12:1254-1257, originally published November 1, 1992 ... Arteriosclerosis, Thrombosis, and Vascular Biology. 1992;12:1254-1257, originally published November 1, 1992 ...http://atvb.ahajournals.org/content/12/11/1254.short
... a single trace leaving the vascular sympodium; leaf vascular bundles amphicribral; guard cells the only epidermal cells with ... endothelium +, nucellar epidermis does not persist; exotestal [!: even when a single integument] cells lignified, esp. on ... TRACHEOPHYTA / VASCULAR PLANTS. Sporophyte long lived, cells polyplastidic, photosynthetic red light response, stomata open in ... There are nectaries at the base of the ovary in the ovary wall, and the number (1, 3) of vascular bundles varies (di Fulvio et ...http://www.mobot.org/MOBOT/Research/APweb/orders/boraginalesweb.htm