Dimercaprol is a chelator and works by binding with heavy metals. It has a very pungent odor. Dimercaprol was first made during ... Dimercaprol is a copper chelating agent that has been approved by the FDA to treat Wilsons disease. Dimercaprol also shows ... Dimercaprol has long been the mainstay of chelation therapy for lead or arsenic poisoning, and it is an essential drug. It is ... Dimercaprol also enhances the toxicity of selenium and tellurium, so it is not to be used to remove these elements from the ...
Get up-to-date information on Dimercaprol side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about ... How was your experience with Dimercaprol?. First, a little about yourself. Male Female ... The Dimercaprol dose your doctor recommends will be based on the following (use any or all that apply): ... Take dimercaprol exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. ...
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WHO Model List of Essential Medicines (2021) / Dimercaprol Dimercaprol. Injection 50 mg/ml Injection 100 mg/mL Injection 50 mg ...
Dimercaprol (BAL in Oil). *View full drug information. British antilewisite is agent of choice in United States. Used as ...
WebMD provides information about interactions between Slo-Release Iron Oral and iron-dimercaprol. ... Dimercaprol/Iron Interactions. This information is generalized and not intended as specific medical advice. Consult your ... Your doctor may tell you to stop taking iron while you are taking dimercaprol. Your doctor may want to test your kidney ... The complex of dimercaprol and iron is toxic and may harm your kidneys. ...
Dimercaprol. *Eltrombopag. *Erdafitinib. *Magnesium Sulfate. *Raltegravir. Using this medicine with any of the following ...
Are we ready to replace dimercaprol (BAL) as an arsenic antidote?. Hum Exp Toxicol. 1997 Aug. 16(8):460-5. [QxMD MEDLINE Link] ...
Prolonged chelation therapy with dimercaprol.. *Cessation of further exposure.. *Surveillance for lung cancer. ...
Dimercaprol was developed as an antidote to lewisite, an arsenic-based war gas and was designated British anti-Lewisite or BAL ... Dimercaprol, penicillamine, N-acetylcysteine, and other chelating agents have been used to treat reactions unresponsive to ... Chelation can be accomplished with oral penicillamine; IV dimercaprol can be used for person who can not take oral medications. ... Specific chelating agents include edetate calcium disodium (EDTA), deferoxamine mesylate (Desferal), dimercaprol (BAL in oil) ...
Dimercaprol (BAL). In: Plumb DC. Plumbs Veterinary Drug Handbook. 9th ed. Ames, IA: Wiley-Blackwell, 2017. ...
Some common chelators include ethylenediaminetetraacetic acid (EDTA), dimercaptosuccinic acid, and dimercaprol.. Some chelators ...
Mass Percentage of Dimercaprol mercury thallium chromium Dimercaprol (HSCH2CHSHCH2OH) is a complexing agent developed during ...
British Anti-Lewisite (BAL), also called Dimercaprol, is a chelating agent shown to reduce systemic effects from Lewisite ... Alkalization of the urine stabilizes the Dimercaprol-metal complex and has been proposed to protect the kidneys during ... If acute renal insufficiency develops, hemodialysis should be considered to remove the Dimercaprol-arsenic complex. Side ...
Acute intermittent porphyria (AIP) is one of the porphyrias, a group of diseases involving defects in heme metabolism and that results in excessive secretion of porphyrins and porphyrin precursors. AIP manifests itself by abdomen pain, neuropathies, and constipation, but, unlike most types of porphyria, patients with AIP do not have a rash.
Oral chelation therapy was started with penicillamine on day 2. EDTA or dimercaprol could not be instituted due to ...
Calcium EDTA is also effective if administered four hours after the administration of dimercaprol. Administering dimercaprol, ... People receiving dimercaprol need to be assessed for peanut allergies since the commercial formulation contains peanut oil. ... Dimercaprol used alone may also redistribute lead to the brain and testes.[240] An adverse side effect of calcium EDTA is renal ... dimercaprol (BAL), which are injected, and succimer and d-penicillamine, which are administered orally.[238]Chelation therapy ...
Dimercaprol, a FDA approved drug, possesses thiol groups and is capable of binding both the carbon-carbon double bond and the ... Taken together, these studies suggest that both dimercaprol and the modified phenelzine analogue may be efficacious acrolein ... At a safe dose, systemic administration of dimercaprol reduced acrolein levels and associated tissue damage, promoted locomotor ... Here, we present two new acrolein scavengers, dimercaprol and a designed phenelzine analogue. Our studies illustrated that both ...
2,3-Dimercaprol has long been the mainstay of chelation therapy for lead or arsenic poisoning in emergency rooms; however, its ... Common side effects associated with Dimercaprol include high blood pressure, vomiting, and fever. Hydrophilic chelators like ... Obviously, with their associated side effects, Dimercaprol and Dimercaptosuccinic acid are only applicable for highly toxic ...
Aktuelle API Auditberichte • GMP-Audits der Herstelung pharmazeutischer Ausgangs- und Wirkstoffe nach ICH Q7 / EU GMP Guide Part II • Diapharm
Two molecules of dimercaprol (BAL) combine with one atom of heavy metal to form a stable complex. BAL enhances fecal and ... Two molecules of dimercaprol (BAL) combine with one atom of heavy metal to form a stable complex. BAL enhances fecal and ... Dimercaprol 2,3-dimercapto-l-propanol BAL Cuprimine D-penicillamine 3-mercapto-D-valine D-penicillamine Chemet Succimer Meso 2, ... the treatment should not be started until after chelation is completed in children receiving dimercaprol (BAL). * EP LEVEL. An ...
dimercaprol *Lacrimation. *docetaxel *Lacrimation increased: postmarketing, rare, 5% - 12% *Lacrimation: postmarketing, rare, 0 ...
Dimercaprol (BAL): Used as an antidote for heavy metal poisoning, such as lead, mercury, or arsenic. ... Chelators such as EDTA, dimercaprol (BAL), penicillamine, and 2,3-dimercaptosuccinic acid (DMSA, succimer. Heavy metal ...
If copper toxicity has caused problems such as anemia or has damaged the kidneys or liver, dimercaprol is injected into a ...
A conventional protocol for acute arsenic intoxication includes dimercaprol administered at a dose of 3 mg/kg intramuscularly ...