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DiethylnitrosamineLiver Neoplasms, ExperimentalNitrosamines2-Acetylaminofluorenegamma-GlutamyltransferaseCarcinogensPhenobarbitalAlkylating AgentsPrecancerous ConditionsRats, Inbred F344LiverCocarcinogenesisLiver NeoplasmsDiethylaminesCarcinogenicity TestsHeptachlor EpoxideGlutathione TransferaseHepatectomyDimethylnitrosamineAdenoma, Liver CellCarcinoma, HepatocellularOrgan SizeOryziasPentachlorophenolNeoplasms, ExperimentalCholine DeficiencyMethyldimethylaminoazobenzeneGlucose-6-PhosphataseAlkylationLiver RegenerationMethylcholanthreneAnticarcinogenic AgentsHepatocytesMethylnitrosoureaBody WeightHistocytochemistryClofibrateRats, Inbred StrainsDeoxyguanosineCell Transformation, NeoplasticHyperplasiaMesocricetusRats, Wistar
Pomegranate action in curbing the incidence of liver injury triggered by Diethylnitrosamine by declining oxidative stress via...Pomegranate action in curbing the incidence of liver injury triggered by Diethylnitrosamine by declining oxidative stress via...
Pomegranate action in curbing the incidence of liver injury triggered by Diethylnitrosamine by declining oxidative stress via ... Pomegranate action in curbing the incidence of liver injury triggered by Diethylnitrosamine by declining oxidative stress via ... Potential preventive effect of carvacrol against diethylnitrosamine-induced hepatocellular carcinoma in rats. Mol Cell Biochem. ... Husain, H., Latief, U. & Ahmad, R. Pomegranate action in curbing the incidence of liver injury triggered by Diethylnitrosamine ...
https://www.nature.com/articles/s41598-018-26611-1?error=cookies_not_supported&code=95459860-5df2-44ba-9d7b-6b786286fb25
Suppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced...Suppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced...
Suppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced ... N-diethylnitrosamine (DEN)-initiated hepatocarcinogenesis. Male F344 rats initiated with DEN were fed the AUR-containing diet ...
https://pubmed.ncbi.nlm.nih.gov/16012713/
The effect of capsaicin and diethylnitrosamine on mouse nephrotoxicity, hepatotoxicity and hepatocarcinogenesis | Acta...
... diethylnitrosamine alone, and diethylnitrosamine and capsaicin in combination in different manners in two groups. After 14 ... Diethylnitrosamine is well known for its toxic and carcinogenic properties affecting mainly liver and kidneys. Capsaicin has ... In this study we used diethylnitrosamine induced mouse experimental model of liver and kidney damage to assess the potential ... In conclusion, our experiment demonstrated the toxic properties of diethylnitrosamine in mice liver and kidneys, with the ...
https://actavet.vfu.cz/89/4/0383/
Tyrosine | GreenMedInfo | Substance | Natural Medicine | AlternativeTyrosine | GreenMedInfo | Substance | Natural Medicine | Alternative
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.Jun ...
https://greenmedinfo.com/substance/tyrosine
Page 1 | Search Results | Cancer Research | American Association for Cancer ResearchPage 1 | Search Results | Cancer Research | American Association for Cancer Research
Kinetics of Diethylnitrosamine Hepatocarcinogenesis in the Infant Mouse. Cancer Res., 43: 4253-4259, 1983 ... Kinetics of Diethylnitrosamine Hepatocarcinogenesis in the Infant Mouse. Cancer Res., ,em,43:,/em, 4253-4259, 1983 in another ... Kinetics of Diethylnitrosamine Hepatocarcinogenesis in the Infant Mouse. Cancer Res., ,em,43:,/em, 4253-4259, 1983 ... of α-Fetoprotein-positive Cells in Hepatocellular Foci and Microcarcinomas Induced by Single Injections of Diethylnitrosamine ...
https://aacrjournals.org/cancerres/search-results?f_AllAuthors=Stanley+Goldfarb
Journal of Complementary and Integrative MedicineJournal of Complementary and Integrative Medicine
Objectives Diethylnitrosamine (DEN) is found in workplaces, processed meats, tobacco smoke, whiskey, etc. It is capable of ... Leaf paste of Telfairia occidentalis favourably modulates deleterious effects associated with exposure to diethylnitrosamine in ...
https://www.degruyter.com/journal/key/jcim/html
Daminozide - WikipediaDaminozide - Wikipedia
... diethylnitrosamine] alone. Daminozide, UDMH, and the combination were not carcinogenic in this model. Groth III, Edward (19 May ...
https://en.wikipedia.org/wiki/Daminozide
Inter Research » DAO » v5Inter Research » DAO » v5
Diethylnitrosamine-induced hepatic neoplasms in the fish Rivulus ocellatus marmoratus DAO 5:39-50 , Full text in pdf format. ...
https://www.int-res.com/abstracts/dao/v5/
CCL4 | Cancer Genetics Web
Animal models of diethylnitrosamine (DEN) or DEN/CCl. RESULTS: Erbin inactivated ERα signaling to drive tumorigenesis of HCC, ... Role of the BrafV637E mutation in hepatocarcinogenesis induced by treatment with diethylnitrosamine in neonatal B6C3F1 mice.. ... Liver inflammation and tumor models of mice were produced by carbon tetrachloride (CCl4) and diethylnitrosamine (DEN) ... injection with diethylnitrosamine after birth and repetitive carbon tetrachloride (CCl. RESULTS: We show that human CCR2. ...
http://www.cancerindex.org/geneweb/CCL4.htm
World Journal of Gastroenterology - Baishideng Publishing GroupWorld Journal of Gastroenterology - Baishideng Publishing Group
Peroxisome proliferator-activated receptor γ ligands suppress liver carcinogenesis induced by diethylnitrosamine in rats. World ... Peroxisome proliferator-activated receptor γ ligands suppress liver carcinogenesis induced by diethylnitrosamine in rats. World ... Peroxisome proliferator-activated receptor γ ligands suppress liver carcinogenesis induced by diethylnitrosamine in rats ...
https://wjgnet.com/1007-9327/CitedArticles?id=10.3748%2Fwjg.v10.i23.3419
Molecules | Free Full-Text | Mustard Seed (Brassica nigra) Extract Exhibits Antiproliferative Effect against Human Lung Cancer...Molecules | Free Full-Text | Mustard Seed (Brassica nigra) Extract Exhibits Antiproliferative Effect against Human Lung Cancer...
... inhibited diethylnitrosamine-initiated hepatocarcinogenesis in rats [30]. ...
https://www.mdpi.com/1420-3049/25/9/2069
Model Details
Chemical/Drug : diethylnitrosamine (DEN) Tumor Synonym. liver tumor. Strain Synonyms. alb-agouti 83 • FVB/N-Tg(Alb1-a)83R ...
https://tumor.informatics.jax.org/mtbwi/tumorSummary.do?strainKey=4294&organOfOriginKey=26&tumorFrequencyKeys=30324,30325
Emerging Roles of Impaired Autophagy in Fatty Liver Disease and Hepatocellular CarcinomaEmerging Roles of Impaired Autophagy in Fatty Liver Disease and Hepatocellular Carcinoma
The study further pointed out that wild-type mice exposed to diethylnitrosamine, a carcinogen, developed only benign tumors. ...
https://www.hindawi.com/journals/ijh/2021/6675762/
Nutrients | Free Full-Text | Molecular Bases Underlying the Hepatoprotective Effects of CoffeeNutrients | Free Full-Text | Molecular Bases Underlying the Hepatoprotective Effects of Coffee
evaluated the effects of coffee or caffeine in a rat model of fibrosis/carcinogenesis induced by diethylnitrosamine (DEN) and ...
https://www.mdpi.com/2072-6643/9/1/85/htm
Frontiers | Glucosinolates From Cruciferous Vegetables and Their Potential Role in Chronic Disease: Investigating the...Frontiers | Glucosinolates From Cruciferous Vegetables and Their Potential Role in Chronic Disease: Investigating the...
Chen and coworkers assessed the effect on mice given diethylnitrosamine before being placed on a Western diet or Western diet ... Dietary Broccoli Lessens Development of Fatty Liver and Liver Cancer in Mice Given Diethylnitrosamine and Fed a Western or ... w/w freeze-dried broccoli before being treated with diethylnitrosamine. The initiation and progression of liver cancer was ... Protects against Fatty Liver Development but Not against Progression of Liver Cancer in Mice Pretreated with Diethylnitrosamine ...
https://www.frontiersin.org/articles/10.3389/fphar.2021.767975/full
SciELO - Brazil - A comparative study to evaluate the effects of antibiotics, plant extracts and fluoride-based toothpaste on...SciELO - Brazil - A comparative study to evaluate the effects of antibiotics, plant extracts and fluoride-based toothpaste on...
Evaluation of chemopreventive and chemotherapeutic effect of Artemisia vulgaris extract against diethylnitrosamine induced ... Evaluation of chemopreventive and chemotherapeutic effect of Artemisia vulgaris extract against diethylnitrosamine induced ...
https://www.scielo.br/j/bjb/a/qGzS8t57ypTCrGrvBtnQqHP/?lang=en
Registration Dossier - ECHARegistration Dossier - ECHA
A) single i.p. administration of 100 mg/kg bw diethylnitrosamine (DEN) at the commencement of the experiment. B) single i.g. ...
https://www.echa.europa.eu/web/guest/registration-dossier/-/registered-dossier/13364/7/8
Mechanisms of chronic alcohol exposure-induced aggressiveness in cellular model of HCC and recovery after alcohol withdrawal |...Mechanisms of chronic alcohol exposure-induced aggressiveness in cellular model of HCC and recovery after alcohol withdrawal |...
... subpopulation after ethanol-fed exposure in Diethylnitrosamine (DEN) HCC model [20, 21]. ...
https://link.springer.com/article/10.1007/s00018-022-04387-y
The EPA National Library Catalog | EPA National Library Network | US EPA
Image Cytometry of Hepatocytes Expressing Gamma-Glutamyl Transpeptidase and Glutathione S-Transferase in Diethylnitrosamine- ...
https://cfpub.epa.gov/ols/catalog/advanced_records_found.cfm?&FIELD1=SUBJECT&INPUT1=Phthalate%20esters&TYPE1=EXACT&LOGIC1=AND
Adult zebrafish as advanced models of human disease | Disease Models & Mechanisms | The Company of BiologistsAdult zebrafish as advanced models of human disease | Disease Models & Mechanisms | The Company of Biologists
Diethylnitrosamine-induced hepatic degeneration and neoplasia in the aquarium fish, brachydanio rerio ...
https://journals.biologists.com/dmm/article/16/8/dmm050351/324979/Adult-zebrafish-as-advanced-models-of-human
KLF6 inhibited oral cancer migration and invasion via downregulation of mesenchymal markers and inhibition of MMP-9 activitiesKLF6 inhibited oral cancer migration and invasion via downregulation of mesenchymal markers and inhibition of MMP-9 activities
Exposure to diethyl nitrosamine can induce more hepatic tumors in KLF6-/+ mouse than in wild-type animals [9]. KLF6 ...
https://www.medsci.org/v14p0530.htm
WikiGenes - CCRIS 3455 - 1,1-dimethylhydrazine; 1,2-dimethylhydrazineWikiGenes - CCRIS 3455 - 1,1-dimethylhydrazine; 1,2-dimethylhydrazine
Comparison of lesions induced in the Syrian golden hamster by diethylnitrosamine, dimethylhydrazine, and dibutylnitrosamine: ... The target organ specificity of the carcinogens diethylnitrosamine [(DENA) CAS: 55-18-5], dimethylhydrazine [(DMH) CAS: 57-14-7 ...
https://www.wikigenes.org/e/chem/e/61870.html
KAKEN - Research Projects | The lineage plasticity fo mature hepatocytes during liver injury and regeneration (KAKENHI-PROJECT...KAKEN - Research Projects | The lineage plasticity fo mature hepatocytes during liver injury and regeneration (KAKENHI-PROJECT...
... we found that part of hepatocyte express SOX9 during formation of hepatocellular carcinoma induced by diethylnitrosamine. Since ...
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K08716/
Saul Villa Personal PageSaul Villa Personal Page
Celecoxib enhances the detoxification of diethylnitrosamine in rat liver cancer. World Journal of Gastroenterolgy 15: 2345-2350 ... Efect of carotenoids against genotoxicity of diethylnitrosamine on rat hepatocytes. Toxicology in Vitro 12: 691-698 ... 2013 Comparative proteomic analysis of thiol proteins in the liver after oxidative stress induced by diethylnitrosamine. ... and anti-genotoxic properties of Calendula officinalis extracts in rat liver cell cultures treated with diethylnitrosamine. ...
http://www.bashanfoundation.org/contributions/Villa-R/villapub.html
Vesanoid (Tretinoin): Uses, Dosage, Side Effects, Interactions, WarningVesanoid (Tretinoin): Uses, Dosage, Side Effects, Interactions, Warning
In a carcinogenicity study, female B5D2F1 mice pretreated with a carcinogen diethylnitrosamine (DEN, intraperitoneal 50 mg/kg ...
https://www.rxlist.com/vesanoid-drug.htm
Potential Antioxidant Role of Tridham in Managing Oxidative Stress against Aflatoxin-B1-Induced Experimental Hepatocellular...Potential Antioxidant Role of Tridham in Managing Oxidative Stress against Aflatoxin-B1-Induced Experimental Hepatocellular...
D3 prevents DNA damage and restores antioxidant enzymes in rat hepatocarcinogenesis induced by diethylnitrosamine and promoted ...
https://www.hindawi.com/journals/ijh/2012/428373/
PDF) Critical review on pharmacological properties of BrahmiPDF) Critical review on pharmacological properties of Brahmi
rats from Diethyl nitrosamine-induced hepatic toxicity (54). Learning and memory: Plant extracts and isolated ...
https://www.researchgate.net/publication/296549746_Critical_review_on_pharmacological_properties_of_Brahmi
SR-BI Antibody - BSA Free (NB400-104): Novus BiologicalsSR-BI Antibody - BSA Free (NB400-104): Novus Biologicals
Accumulation of cholesterol, triglycerides and ceramides in hepatocellular carcinomas of diethylnitrosamine injected mice ...
https://www.novusbio.com/products/sr-bi-antibody_nb400-104
Broccoli Benefits: Cruciferous Vegetables May Protect Against Liver Cancer, But Refrain From Eating Too MuchBroccoli Benefits: Cruciferous Vegetables May Protect Against Liver Cancer, But Refrain From Eating Too Much
Dietary broccoli lessens development of fatty liver and liver cancer in mice given diethylnitrosamine and fed a Western or ...
https://www.medicaldaily.com/broccoli-benefits-cruciferous-vegetable-376641