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*  The Ogg1 protein of Saccharomyces cerevisiae: a 7,8-dihydro-8-oxoguanine DNA glycosylase/AP lyase whose lysine 241 is a...
... formamidopyrimidine-DNA glycosylase): excision of purine lesions in DNA produced by ionizing radiation or photosensitization. ... 6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase of Escherichia coli and an activity nicking DNA at apurinic/ ... de Oliveira R, van der Kemp PA, Thomas D, Geiger A, Nehls P, Boiteux S. Formamidopyrimidine DNA glycosylase in the yeast ... Boiteux S, Huisman O. Isolation of a formamidopyrimidine-DNA glycosylase (fpg) mutant of Escherichia coli K12. Mol Gen Genet. ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC146873/
*  Induction and repair inhibition of oxidative DNA damage by nickel(II) and cadmium(II) in mammalian cells. : Carcinogenesis - oi
... determined the frequencies of DNA strand breaks and of lesions recognized by the bacterial formamidopyrimidine-DNA glycosylase ... As indicators of oxidative DNA damage, we determined the frequencies of DNA strand breaks and of lesions recognized by... ... DNA strand breaks occurred at 10 microM and no Fpg-sensitive sites were detected. However, the repair of Fpg-sensitive DNA ... In the present study we used human HeLa cells to investigate the potential of nickel(II) and cadmium(II) to induce DNA lesions ...
  http://oxfordindex.oup.com/view/10.1093/carcin/18.5.1021
*  DNA-formamidopyrimidine glycosylase - Wikipedia
... formamidopyrimidine-DNA glycosylase, formamidopyrimidine-DNA glycosylase, DNA-formamidopyrimidine glycosidase, Fpg protein) is ... DNA-formamidopyrimidine glycosylase (EC 3.2.2.23, Fapy-DNA glycosylase, deoxyribonucleate glycosidase, 2,6-diamino-4-hydroxy-5N ... DNA-formamidopyrimidine glycosylase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... Boiteux, S.; O'Connor, T.R.; Laval, J. (1987). "Formamidopyrimidine-DNA glycosylase of Escherichia coli: cloning and sequencing ...
  https://en.wikipedia.org/wiki/DNA-formamidopyrimidine_glycosylase
*  mutM - Formamidopyrimidine-DNA glycosylase - Burkholderia pseudomallei - mutM gene & protein
Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8 ... 8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta ... Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. ... IPR015886 DNA_glyclase/AP_lyase_DNA-bd. IPR015887 DNA_glyclase_Znf_dom_DNA_BS. IPR020629 Formamido-pyr_DNA_Glyclase. IPR012319 ...
  https://www.uniprot.org/uniprot/A0A069AXT4
*  RCSB PDB - Protein Feature View - Formamidopyrimidine-DNA glycosylase - P42371 (FPG LACLC)
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes ... lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single- ...
  http://www.rcsb.org/pdb/protein/P42371
*  mutM - Formamidopyrimidine-DNA glycosylase - Phenylobacterium zucineum (strain HLK1) - mutM gene & protein
Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8 ... 8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta ... Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. ... Formamidopyrimidine-DNA glycosylaseUniRule annotation. ,p>Manual validated information which has been generated by the ...
  http://www.uniprot.org/uniprot/B4RC43
*  mutM - Formamidopyrimidine-DNA glycosylase - Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) - mutM gene & protein
Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8 ... 8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta ... Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. ... Formamidopyrimidine-DNA glycosylaseUniRule annotation. ,p>Manual validated information which has been generated by the ...
  http://www.uniprot.org/uniprot/Q6FE90
*  Formamidopyrimidine DNA glycosylase - Wikipedia
"Crystal structure of the Lactococcus lactis formamidopyrimidine-DNA glycosylase bound to an abasic site analogue-containing DNA ... Formamidopyrimidine DNA glycosylase (FPG) is a base excision repair enzyme which recognizes and removes a wide range of ... "Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from ... oxidized purines from correspondingly damaged DNA. It was discovered by Zimbabwean scientist Christopher J. Chetsanga in 1975. ...
  https://en.wikipedia.org/wiki/Formamidopyrimidine_DNA_glycosylase
*  mutM - Formamidopyrimidine-DNA glycosylase - Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99) - mutM gene & protein
Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8 ... 8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta ... Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. ... IPR015886. DNA_glyclase/AP_lyase_DNA-bd. IPR015887. DNA_glyclase_Znf_dom_DNA_BS. IPR020629. Formamido-pyr_DNA_Glyclase. ...
  http://www.uniprot.org/uniprot/B2VF70
*  Sensitive detection of formamidopyrimidine-DNA glycosylase activity based on target-induced self-primed rolling circle...
Herein, a unique nick (8-oxoguanine, 8-oxoG) was positioned in duplex DNA containing P-circle and P1, whi RSC papers by GRC ... We developed a novel approach to determine formamidopyrimidine DNA glycosylase (FPG) activity by taking advantage of target- ... Sensitive detection of formamidopyrimidine-DNA glycosylase activity based on target-induced self-primed rolling circle ... Sensitive detection of formamidopyrimidine-DNA glycosylase activity based on target-induced self-primed rolling circle ...
  http://pubs.rsc.org/en/content/articlelanding/2018/an/c7an02032e
*  Molecular dynamics simulation of the opposite-base preference and interactions in the active site of formamidopyrimidine-DNA...
The side chains of Arg109 and Phe111 that Fpg inserts into DNA to maintain its kinked conformation tended to withdraw from ... The crystal structures of several Fpg-DNA complexes have been solved, yet no structure with A opposite the lesion is available ... Here we use molecular dynamic simulation to model interactions in the pre-catalytic complex of Lactococcus lactis Fpg with DNA ... Overall, the discrimination against A opposite to the lesion seems to be due to incorrect DNA distortion around the lesion- ...
  https://bmcstructbiol.biomedcentral.com/articles/10.1186/s12900-017-0075-y
*  LMG 10879 Strain Passport - StrainInfo
Stenotrophomonas maltophilia isolate 891 DNA-formamidopyrimidine glycosylase (mutM) gene, partial cds. LMG 10879 ... Stenotrophomonas maltophilia partial gyrB gene for DNA gyrase subunit B, isolate LMG 10879. LMG 10879 ...
  http://www.straininfo.net/strains/26634
*  LMG 10991 Strain Passport - StrainInfo
Stenotrophomonas maltophilia isolate 892 DNA-formamidopyrimidine glycosylase (mutM) gene, partial cds. LMG 10991 ...
  http://www.straininfo.net/strains/26704
*  ATCC 15099 Strain Passport - StrainInfo
Stenotrophomonas maltophilia isolate 889 DNA-formamidopyrimidine glycosylase (mutM) gene, partial cds. LMG 10873 ... Stenotrophomonas maltophilia partial gyrB gene for DNA gyrase subunit B, isolate LMG 10873. LMG 10873 ...
  http://www.straininfo.net/strains/26612
*  ATCC 17671 Strain Passport - StrainInfo
Stenotrophomonas maltophilia isolate 890 DNA-formamidopyrimidine glycosylase (mutM) gene, partial cds. LMG 10874 ... Stenotrophomonas maltophilia partial gyrB gene for DNA gyrase subunit B, isolate LMG 10874. LMG 10874 ...
  http://www.straininfo.net/strains/26615
*  Search: All Pfam signatures | InterPro | EMBL-EBI
Formamidopyrimidine-DNA glycosylase, catalytic domain (IPR012319) Pfam signature: PF01149 Nucleoside phosphatase GDA1/CD39 ( ... DNA-directed DNA polymerase, family B, multifunctional domain (IPR006134) Pfam signature: PF00136 ... DNA-directed DNA polymerase, family A, palm domain (IPR001098) Pfam signature: PF00476 ... Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding (IPR014048) Pfam signature: PF01035 ...
  http://www.ebi.ac.uk/interpro/member-database/Pfam
*  MTH1 deficiency selectively increases non-cytotoxic oxidative DNA damage in lung cancer cells: more bad news than good? |...
Formamidopyrimidine-DNA glycosylase (Fpg)-modified alkaline comet assay to determine DNA damage levels (expressed as % tail DNA ... DNA damage was assessed using Formamidopyrimidine-DNA glycosylase (Fpg)-modified comet assay that is a slight modification of ... Oxidised DNA bases do not majorly disrupt DNA structure; however, they can subsequently lead to secondary types of DNA damage ... such as DNA mispairs [10], DNA single-strand breaks (SSBs) that arise when DNA glycosylases remove damaged bases during base ...
  https://rd.springer.com/article/10.1186/s12885-018-4332-7
*  Sequence Similarity - 1PJI: Crystal structure of wild type Lactococcus lactis FPG complexed to a 1,3 propanediol...
... comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNA. ... Formamidopyrimidine-DNA glycosylase protein, length: 271 (BLAST) Sequence Similarity Cutoff. Rank. Chains in Cluster. Cluster ... DNA (5'-D(*CP*TP*CP*TP*TP*TP*(PDI)P*TP*TP*TP*CP*TP*CP*G)-3') dna, length: 14 (BLAST) ... DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3') dna, length: 14 (BLAST) ...
  http://www.rcsb.org/pdb/explore/sequenceCluster.do?structureId=1PJI
*  IL36RN Polyclonal Antibody - Gentaur.com
konkukian Formamidopyrimidine-DNA glycosylase (mutM). Supplier:MyBioSource. Price:906.81USD. Paeonol 20mg ...
  https://gentaur.com/prod/il36rn-polyclonal-antibody/biomatik/2103265679
*  UniProt: Q4QLW2
DE RecName: Full=Formamidopyrimidine-DNA glycosylase {ECO:0000255,HAMAP-Rule:MF_00103}; DE Short=Fapy-DNA glycosylase {ECO: ... DNA_glyclase/AP_lyase_DNA-bd. DR InterPro; IPR015887; DNA_glyclase_Znf_dom_DNA_BS. DR InterPro; IPR020629; Formamido-pyr_DNA_ ... ECO:0000250}. FT CHAIN 2 271 Formamidopyrimidine-DNA glycosylase. FT /FTId=PRO_0000228438. FT ZN_FING 235 269 FPG-type. {ECO: ... DNA damage; DNA repair; DNA-binding; Glycosidase; KW Hydrolase; Lyase; Metal-binding; Multifunctional enzyme; Zinc; KW Zinc- ...
  http://www.genome.jp/dbget-bin/www_bget?uniprot:Q4QLW2
*  MYPE2000
Fapy_DNA_glyco. 1. Formamidopyrimidine-DNA glycosylase N-. 2-119. 164.4. 3.3e-46 H2TH. 1. Formamidopyrimidine-DNA glycosylase ... gi,15828781 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (FAPY-DNA GLYCOSYLASE) [Mycoplasma pulmonis]. 217. 1.5e-58 mmob. gi,47459207 ... formamidopyrimidine-DNA glycosylase [Mycoplasma pneumoniae M129] 643. 2.3e-65. gi,188524384. formamidopyrimidine-DNA ... MPN380 fpg Formamidopyrimidine-DNA glycosylase 457147:457980. 271. 9.2e-75 mgen. gi,12045118 formamidopyrimidine-DNA ...
  http://www0.nih.go.jp/Mypet/gview/view_annon.cgi?molecule=MYPE&id=2000
*  NWMN RS08875 - AureoWiki
Genetic information processingDNA metabolismDNA replication, recombination, and repairDNA-formamidopyrimidine glycosylase ( ... DNA-formamidopyrimidine glycosylaseHydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4- ... no clan definedFapy_DNA_glyco; Formamidopyrimidine-DNA glycosylase N-terminal domain (PF01149; HMM-score: 99.2) ... H2TH (CL0303) H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain (PF06831; HMM-score: 70.1) ...
  http://aureowiki.med.uni-greifswald.de/NWMN_RS08875
*  Regulation and characterization of four CBF transcription factors from Brassica napus, Plant Molecular Biology | 10.1023/A...
Multiple forms of formamidopyrimidine-DNA glycosylase produced by alternative splicing in Arabidopsis thaliana ... Complementary DNA sequence of a low temperature-induced Brassica napus gene with homology to the Arabidopsis thaliana kin1 gene ... All four BNCBF clones encode a putative DRE/CRT (LTRE)-binding protein with an AP2 DNA-binding domain, a putative nuclear ... A maize DNA-binding factor with a bZIP motif is induced by low temperature ...
  https://www.deepdyve.com/lp/springer_journal/regulation-and-characterization-of-four-cbf-transcription-factors-from-P1C3O7VKBf
*  Affi-GelĀ® Blue Gel | Process Separations | Bio-Rad
DNA polymerase. Calf thymus. 0-0.5 M KCl. Formamidopyrimidine-DNA glycosylase. E. coli. 0.1-0.8 M KCl. ...
  http://www.bio-rad.com/en-ca/product/ready-use-affinity-media/affi-gel-blue-gel?pcp_loc=lnav
*  Complete medium | definition of complete medium by Medical dictionary
Formamidopyrimidine-DNA Glycosylase Enhances Arsenic-Induced DNA Strand Breaks in PHA-Stimulated and Unstimulated Human ...
  http://medical-dictionary.thefreedictionary.com/Complete+medium