Initiation of polyoma virus DNA synthesis : a mutational analysis
Initiation of polyoma virus DNA synthesis: a mutational analysis. Österlund, Mårten Uppsala University, Disciplinary Domain of ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:294505
Biology | Free Full-Text | A Comparison of Two Single-Stranded DNA Binding Models by Mutational Analysis of APOBEC3G
... but none reveal how this enzyme binds to substrate single-stranded DNA. Here, we constructed a panel of APOBEC3G amino acid ... APOBEC3G is the best known of several DNA cytosine deaminases that function to inhibit the replication of parasitic genetic ... A Comparison of Two Single-Stranded DNA Binding Models by Mutational Analysis of APOBEC3G. Keisuke Shindo †. ... "A Comparison of Two Single-Stranded DNA Binding Models by Mutational Analysis of APOBEC3G." Biology 1, no. 2: 260-276. ...http://mdpi.com/2079-7737/1/2/260/xml
A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers.
DNA repair, cell-cycle checkpoints, and transcriptional regulation. BRCA1 germline mutations confer a high risk of early-onset ... DNA Mutational Analysis. DNA Repair-Deficiency Disorders. DNA, Neoplasm / analysis. Death-Associated Protein Kinases. Female. ... BRCA1 breast cancers displayed a mutational signature consistent with that caused by lack of HR DNA repair in both ER-positive ... Sequencing analysis of independent cohorts of hereditary BRCA1 and sporadic non-BRCA1 breast cancers for the presence of ...http://www.biomedsearch.com/nih/whole-genome-massively-parallel-sequencing/22362584.html
Mutational spectrum induced in Saccharomyces cerevisiae by the carcinogen N-2-acetylaminofluorene.
DNA Adducts. DNA Mutational Analysis. DNA, Fungal. Molecular Sequence Data. Mutagenicity Tests. Mutagens / toxicity*. Orotidine ... 0/DNA Adducts; 0/DNA, Fungal; 0/Mutagens; 53-96-3/2-Acetylaminofluorene; EC 18.104.22.168/Orotidine-5'-Phosphate Decarboxylase ... Sequence analysis of the URA3 mutants revealed approximately 48% frameshifts, approximately 44% base substitutions and ...http://www.biomedsearch.com/nih/Mutational-spectrum-induced-in-Saccharomyces/7845359.html
A general role of the DNA glycosylase Nth1 in the abasic sites cleavage step of base excision repair in Schizosaccharomyces...
One of the most frequent lesions formed in cellular DNA are abasic (apurinic/apyrimidinic, AP) sites that are both cytotoxic ... DNA Glycosylases / genetics, metabolism, physiology*. DNA Mutational Analysis. DNA Repair*. DNA-(Apurinic or Apyrimidinic Site ... phoshodiesterase or dRPase leaving a gap in DNA. The gap is filled by a DNA polymerase and the strand sealed by a DNA ligase. ... DNA glycosylase activities in cell extracts from S.pombe. (A) Cleavage of A/8oxoG-containing duplex DNA. An aliquot of 0.5 and ...http://www.biomedsearch.com/nih/general-role-DNA-glycosylase-Nth1/15452279.html
MYD88 | Cancer Genetics Web
To investigate the mutational profile of PCNSL, we analyzed nine paired tumor and germline DNA samples from PCNSL patients by ... Mutational analysis of primary central nervous system lymphoma.. Oncotarget. 2014; 5(13):5065-75 [PubMed] Article available ... Literature Analysis. Mouse over the terms for more detail; many indicate links which you can click for dedicated pages about ... Analysis of BRAF and NRAS showed mutation frequencies of 4.8 and 9.5%, respectively. No MYD88 mutations could be detected in ...http://www.cancerindex.org/geneweb/MYD88.htm
EXTL1 | Cancer Genetics Web
... we performed 1p deletion analysis and mutation screening of the EXTL1-coding region on DNA from 22 primary neuroblastomas and ... Literature Analysis. Mouse over the terms for more detail; many indicate links which you can click for dedicated pages about ... Mutation analysis of hereditary multiple exostoses in the Chinese.. Hum Genet. 1999 Jul-Aug; 105(1-2):45-50 [PubMed] Related ... Genetic analyses have revealed HME to be a multigenic disorder linked to three loci on chromosomes 8q24 (EXT1), 11p11-13 (EXT2 ...http://www.cancerindex.org/geneweb/EXTL1.htm
An overview of familial Mediterranean fever with emphasis on pyrin and colchicine.
DNA Mutational Analysis. Exons / genetics. Familial Mediterranean Fever / diagnosis, drug therapy*, genetics*. Genetics, ... 23051629 - Predictors of braf mutation in melanocytic nevi: analysis across regions with different.... 24440239 - Spectrum and ... 24148579 - Inherited common variants in mitochondrial dna and invasive serous epithelial ovarian c.... 23317199 - Association ... 1456289 - Familial mediterranean fever: analysis of inheritance and current linkage data.. 9713229 - Linear epidermolytic ...http://www.biomedsearch.com/nih/overview-familial-Mediterranean-fever-with/19534089.html
FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy.
DNA Mutational Analysis. Disease-Free Survival. Female. Gene Frequency. Genetic Predisposition to Disease / genetics. Genotype ...http://www.biomedsearch.com/nih/Fgfr3-hras-kras-nras-pik3ca/21072204.html
VHL | Cancer Genetics Web
DNA Mutational Analysis. *Basic Helix-Loop-Helix Transcription Factors. *Single Nucleotide Polymorphism ... Literature Analysis. Mouse over the terms for more detail; many indicate links which you can click for dedicated pages about ... Mutational status of VHL gene and its clinical importance in renal clear cell carcinoma.. Virchows Arch. 2014; 465(3):321-30 [ ... Genomic DNA was isolated from normal and tumor tissues of 19 renal cell carcinoma patients. The samples were screened for ...http://www.cancerindex.org/geneweb/VHL.htm
Laryngeal involvement in the Dowling-Meara variant of epidermolysis bullosa simplex with keratin mutations of severely...
DNA Mutational Analysis. Epidermolysis Bullosa Simplex / genetics*, pathology. Female. Humans. Infant, Newborn. Keratins / ... Molecular analysis confirmed the diagnosis by identification of mis-sense point mutations in basal cell keratin genes in both ...http://www.biomedsearch.com/nih/Laryngeal-involvement-in-Dowling-Meara/10730767.html
A genome-wide screen and linkage mapping for a large pedigree with episodic ataxia.
DNA Mutational Analysis. Diagnosis, Differential. Female. Genetic Markers / genetics*. Genetic Predisposition to Disease / ... Haplotype analysis and fine mapping yielded a peak 2-point lod score of 4.14 and indicated a 4-cM region on 1q42 that is likely ...http://www.biomedsearch.com/nih/genome-wide-screen-linkage-mapping/16009908.html
PRSS1 | Cancer Genetics Web
DNA Mutational Analysis. *VEGFA. *alpha-Fetoproteins. *Cystic Fibrosis Transmembrane Conductance Regulator. Tag cloud generated ... Multiple single SNP analyses showed associations, which will require replication. Exploratory pathway analyses by recursive ... Association studies were done at the gene level by principal components analysis, whereas recursive partitioning analysis was ... A case-control analysis revealed a 0.118-fold (95% CI: 0.037-0.653), 0.842-fold (95% CI: 0.177-4.010), and 0.750-fold (95% CI: ...http://www.cancerindex.org/geneweb/PRSS1.htm
Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy.
DNA Mutational Analysis. Dimethylallyltranstransferase / chemistry, genetics*, metabolism. Female. Genetic Linkage. Genotype. ... To facilitate phase determination during subsequent haplotype analysis, we collected DNA specimens from as many family members ... We used the Oragene kits from DNA Genotek (Ottawa, Canada) for self-collection of salivary DNA (particularly in situations ... nor 59 Caucasian HapMap DNA samples (118 chromosomes), nor 89 Asian HapMap DNA samples (178 chromosomes), nor are any of these ...http://www.biomedsearch.com/nih/Mutations-in-UBIAD1-gene-encoding/17668063.html
FLT3 | Cancer Genetics Web
Mutational analysis of certain genes, such as SF3B1, is also becoming an important tool to distinguish subsets of MDS that have ... DNA for every AML patient was extracted and underwent PCR with FLT3-ITD primers.. RESULTS: The mean age at diagnosis was 28.5 ... with data confirmed by state-of-the-art analyses of internalization, cell biology, gene analysis for FLT3-IDT gene, and Western ... Molecular genetic analysis of CEBPA, NPM1, and FLT3 is already standard of care in patients with AML, and mutations in several ...http://www.cancerindex.org/geneweb/FLT3.htm
NPM1 | Cancer Genetics Web
Mutational analysis of certain genes, such as SF3B1, is also becoming an important tool to distinguish subsets of MDS that have ... We analyzed DNA samples from 20 childhood (cAML) and 20 adult AML (aAML) patients, using NGS targeted sequencing. The average ... Mutational analysis of JAK2, CBL, RUNX1, and NPM1 genes in familial aggregation of hematological malignancies.. Ann Hematol. ... Molecular genetic analysis of CEBPA, NPM1, and FLT3 is already standard of care in patients with AML, and mutations in several ...http://www.cancerindex.org/geneweb/NPM1.htm
R25C mutation in the NKX2.5 gene in Italian patients affected with non-syndromic and syndromic congenital heart disease.
DNA Mutational Analysis / methods. Dogs. Gene Frequency. Genetic Predisposition to Disease. Heart Defects, Congenital / ... and mutational analysis was performed using denaturing high performance liquid chromatography and DNA sequencing.. RESULTS: One ... The coding region and flanking regions involved in gene splicing of the CSX/NKX2.5 gene were amplified from genomic DNA by PCR ...http://www.biomedsearch.com/nih/R25C-mutation-in-NKX25-gene/22964646.html
Primary - U of U School of Medicine - | University of Utah
DNA Mutational Analysis, Flow Cytometry, Molecular Genetics. Lab URL. https://dna.utah.edu ... DNA Alterations in Primary and Circulating Tumors, Non-Coding RNAs for Cancer Classification, Detection, and Monitoring, ... GC/MS and LC/MS Techniques for Analysis of Drugs in Biological Matrices, Metabolism of Drugs and Environmental Toxins in Human ... Economic Evaluation of Diagnostic Tests, Comparative Effectiveness of Diagnostic Tests, Operations Analysis, Research Synthesis ...http://medicine.utah.edu/pathology/faculty/
FOXL2 gene | Cancer Genetics Web
In addition, DNA replication error, on analysis of the lengths of CAG repeats in androgen receptor gene, revealed defective DNA ... DNA binding - DNA binding, bending - double-stranded DNA binding - embryonic eye morphogenesis - estrogen receptor binding - ... DNA methylation patterns and histone modification analysis; identification of splicing isoforms and of DNA regions that ... Advances in our understanding of the molecular basis of tumors, as well as in the technology of DNA analysis, are rapidly ...http://www.cancerindex.org/geneweb/FOXL2.htm
Localization of FLAG-tagged wild type and mutant NHS-A | Open-i
DNA Mutational Analysis. *Dogs. *Humans. *Male. *Molecular Sequence Data. *Mutagenesis. *Protein Isoforms/genetics/metabolism ... Mutation analysis also shed light on the significance of NHS-A regions for its localization and, hence, its function at ... Mutation analysis also shed light on the significance of NHS-A regions for its localization and, hence, its function at ... The mislocalization of the mutant NHS-A protein, revealed by mutation analysis, is expected to adversely affect cell-cell ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC2571945_mv-v14-1856-f4&req=4
basal cell adenoma morphologic abnormality 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
DNA Mutational Analysis. Female. Humans. *[Email] Email this result item Email the results to the following email address: [X] ... MeSH-major] Antigens, CD / analysis. Membrane Glycoproteins / analysis. Neoplasm Proteins / analysis. Parotid Gland / chemistry ... MeSH-major] Actins / analysis. Keratins / analysis. Neoplasm Proteins / analysis. Salivary Gland Neoplasms / pathology ... MeSH-major] DNA, Neoplasm / analysis. Flow Cytometry. Ploidies. Salivary Gland Neoplasms / diagnosis ...http://www.bmlsearch.com/?kwr=basal+cell+adenoma+morphologic+abnormality+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
acute myeloblastic leukaemia without maturation 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
DNA Mutational Analysis. DNA, Neoplasm / genetics. Disease-Free Survival. Female. Humans. Infant. Kaplan-Meier Estimate. Male. ... Antigens, CD7 / analysis. Antigens, CD79 / analysis. Antigens, Neoplasm / analysis. Biomarkers, Tumor / analysis. Leukemia, ... Skladanowski A, Bozko P, Sabisz M, Larsen AK: Dual inhibition of PI3K/Akt signaling and the DNA damage checkpoint in p53- ... Øyan AM, Bø TH, Jonassen I, Gjertsen BT, Bruserud Ø, Kalland KH: cDNA microarray analysis of non-selected cases of acute ...http://www.bmlsearch.com/?kwr=acute+myeloblastic+leukaemia+without+maturation+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
adult optic nerve glioma 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
DNA Mutational Analysis. Disease Susceptibility. Genetic Counseling. Genetic Predisposition to Disease / genetics. Genetic ... Liu B, Liang YS, Shi XE, Zhang QJ: [Preoperative diagnosis and microsurgery of the optic gliomas:retrospective analysis of 7 ... Rizvi SA, Gupta Y, Gupta M: Surgical treatment and histopathological analysis of proptosis. Nepal J Ophthalmol; 2010 Jan-Jun;2( ... Meta-Analysis. Practice Guideline. Randomized Controlled Trial. Review. More publication types:. Addresses. Bibliography. ...http://www.bmlsearch.com/?kwr=adult+optic+nerve+glioma+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
basal cell carcinoma with adnexal differentiation 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
DNA Mutational Analysis. Female. Gene Expression Regulation, Neoplastic. Humans. Male. Middle Aged. Molecular Sequence Data. ... Trans-Activators / analysis. Tumor Suppressor Proteins / analysis. *MedlinePlus Health Information. consumer health - Skin ... Meta-Analysis. Practice Guideline. Randomized Controlled Trial. Review. More publication types:. Addresses. Bibliography. ... MeSH-major] Biomarkers, Tumor / analysis. Carcinoma, Basal Cell / diagnosis. Carcinoma, Skin Appendage / diagnosis. Skin ...http://www.bmlsearch.com/?kwr=basal+cell+carcinoma+with+adnexal+differentiation+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
adult intracranial germ cell tumor 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
DNA Mutational Analysis. Female. Gene Expression Profiling. Humans. Immunohistochemistry. Male. Middle Aged. Mutation, Missense ... DNA Mutational Analysis. Female. Humans. Infant. Male. Microsatellite Repeats / genetics. Pedigree. Sex Characteristics. ... Survival Analysis. Syndrome. Time Factors. *[Email] Email this result item Email the results to the following email address: [X ... Lee D, Suh YL: Histologically confirmed intracranial germ cell tumors; an analysis of 62 patients in a single institute. ...http://www.bmlsearch.com/?kwr=adult+intracranial+germ+cell+tumor+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
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