Cytochalasin - Wikipedia
Cytochalasin A Cytochalasin B Cytochalasin C Cytochalasin D Cytochalasin E Cytochalasin F Cytochalasin H Cytochalasin J ... cytochalasin A and cytochalasin B can also inhibit the transport of monosaccharides across the cell membrane, cytochalasin H ... cytochalasin D inhibits protein synthesis and cytochalasin E prevents angiogenesis. Cytochalasins are known to bind to the ... One cytochalasin will bind to one actin filament. Studies done with cytochalasin D (CD) have found that CD-actin dimers contain ...
Fermentek | Cytochalasin E ( 36011-19-5 )
Cytochalasins are a group of about 20 known mycotoxins, which affect actin stress fibers, causing actin depolymerization. ... Cytochalasin E Inhibits actin polymerization in blood platelets. It does not inhibit glucose transport. ...
Platelet Aggregation Is Not Initiated by Platelet Shape Change | Laboratory Investigation
... and when platelets were activated in the presence of shape-change inhibitors such as cytochalasin D and vincristine. Microscopy ... Addition of cytochalasin D preserved the discoid morphology of platelets (Fig. 6A) even after addition of thrombin. A thrombin ... Cytochalasin D and PGE1 were dissolved in dimethysulfoxide (DMSO). DMSO alone had no effect on platelet aggregation when added ... PRP was placed in the aggregometer at 37° C, the stirrer was turned on to 1000 rpm, and 60 μm cytochalasin D was added followed ...
Effects of Cytochalasin B in Culture and in Vivo on Murine Madison 109 Lung Carcinoma and on B16 Melanoma<...
Effects of Cytochalasin B in Culture and in Vivo on Murine Madison 109 Lung Carcinoma and on B16 Melanoma. In: Cancer Research ... Effects of Cytochalasin B in Culture and in Vivo on Murine Madison 109 Lung Carcinoma and on B16 Melanoma. Cancer Research. ... N2 - Cytochalasin B (CB), at 100 or at 10 mg/kg single dose s.c. in carboxymethyl-cellulose (2%)/Tween-20 (1%) 24 h after s.c. ... AB - Cytochalasin B (CB), at 100 or at 10 mg/kg single dose s.c. in carboxymethyl-cellulose (2%)/Tween-20 (1%) 24 h after s.c. ...
Cytochalasin D restores nuclear size acting on F-actin and IZUMO1 localization in low-quality spermatozoa
... Int J Biol Sci. 19(7 ... Cytochalasin D restores nuclear size acting on F-actin and IZUMO1 localization in low-quality spermatozoa Guillaume Martinez1,2 ... Accordingly, depolymerization of F-actin, induced by in vitro Cytochalasin-D (CYTO-D) treatment, restored the normal IZUMO1 and ... A correct IZUMO1 repositioning following in vitro induction of F-actin depolymerization, by cytochalasin D treatment, occurred ...
Toxins | Free Full-Text | Multi-Mycotoxin Screening Reveals the Occurrence of 139 Different Secondary Metabolites in Feed and...
Colistin Toku E - World of Odes
Validation of Osteogenic Properties of Cytochalasin D by High-Resolution RNA-Sequencing in Mesenchymal Stem Cells Derived from...
Cancers | Free Full-Text | Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for...
Cytochalasins. Inhibits polymerization by binding F-actin. [189,190]. Latrunculin. Inhibits polymerization. Enhances ... Calaghan, S.C.; White, E.; Bedut, S.; Le Guennec, J.Y. Cytochalasin D reduces Ca2+ sensitivity and maximum tension via ... In vitro growth inhibitory effects of cytochalasins and derivatives in cancer cells. Planta Med. 2011, 77, 711-717. [Google ...
Registration Dossier - ECHA
After this period, Cytochalasin B (4 µg/mL) was added and the cells were cultured another approximately 20 hours until ... Cytochalasin B. Metabolic activation:. with and without. Metabolic activation system:. Phenobarbital/beta-naphthoflavone ... After washing, the cells were re-suspended in complete culture medium containing 10 % FBS (v/v). Cytochalasin B (4 µg/mL) was ...
Registration Dossier - ECHA
Cytochalasin B (Sigma) was added to the cells simultaneously with the test item at the 24 hour exposure time. A vehicle control ... Cytochalasin B (Sigma) was added to the cells simultaneously with the test item at the 24 hour exposure time.. - Properly ... Cytochalasin B. Metabolic activation:. with and without. Metabolic activation system:. Phenobarbital/ß-naphthoflavone induced ... After a second centrifugation step, HBSS was removed and cells were resuspended in 5 mL culture medium with cytochalasin B (5 ...
Registration Dossier - ECHA
Macrophage phagocytosis of SARS-CoV-2-infected cells mediates potent plasmacytoid dendritic cell activation | Cellular &...
For the phagocytosis inhibitory experiments, MDMs were pretreated for 2 h with Cytochalasin D (CytD; 5 µM; CAYMAN chemical ... for 18 h and cocultured with SARS-CoV-2-infected cells in the absence or presence of the phagocytosis inhibitor cytochalasin D ...
INTERCHIM: Toxicology, Toxicity Assays
Host-induced spermidine production in motile Pseudomonas aeruginosa triggers phagocytic uptake | eLife
Cytochalasin D was added to cell cultures at the indicated concentrations 30 min prior to infection to block phagocytosis. Upon ... Addition of 10 µM cytochalasin D to the culture medium blocked bacterial uptake to less than 1% (Figure 2-figure supplement 1D ... C) Adherence of bacterial cells to RAW264.7 macrophages following treatment with 10 µM cytochalasin D to inhibit phagocytic ... The initial bacterial load was set to 100% (black, technical replicates) while the bacterial uptake without cytochalasin D is ...
Inhibition of Induced Micronuclei Formation in Human Lymphocytes by Ginger
Cytochalasin B. Three milligram was dissolved in 10 mL of 1:1 dimethyl sulfoxide and water and was refrigerated at -20 °C. It ... Cytochalasin B was added at the 44th h after setting the cultures. ...
15.4.3.6.3
Cytochalasin B inhibits phagocytosis [3366]; Cytochalasin D, a drug that affects actin polymerization and particle ... Colchicine (at 150 mg/kg) and cytochalasin B (at 0.15 mg/kg) greatly depress pulmonary macrophage endocytosis or "particle ...
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Wissenschaftliche Publikationen | Max-Planck-Gesellschaft
Nesprins and opposing microtubule motors generate a point force that drives directional nuclear motion in migrating neurons |...
Treatment with the actin depolymerizer cytochalasin B (20 μM) immediately disrupted the actin cytoskeleton, as revealed by ... cytochalasin B (20 μM; Sigma), taxol (5 μM; Sigma) or nocodazole (1 μM; Sigma) dissolved in DMSO. For imaging of migration in ...
The JAX Synteny Browser for mouse-human comparative genomics. - SyMAP - Synteny browser for plant genomes, including Medicago...
Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids
Bovine parthenogenotes produced by inhibition of first or second polar bodies emission
Cytochalasin B, an inhibitor of actin microfilaments, was employed during in vitro maturation to inhibit first polar body ... In experiment 1, the effect of cytochalasin B on in vitro maturation of bovine oocytes was evaluated. Most oocytes (77%) were ... meiotic maturation, microfilaments, cytochalasin B, parthenogenesis Cite This Article. J., R. (2011). Bovine parthenogenotes ... In experiment 2, development of embryos exposed to cytochalasin B during in vitro maturation (CytoB-IVM) or during activation ( ...
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JCI - CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment
Chemicals. Cytochalasin D, latrunculin B, and jasplakinolide (Sigma-Aldrich) were used to inhibit actin polymerization in tumor ... Furthermore, cytochalasin D inhibited the secretion of soluble CD73, confirming that actin polymerization was essential also ... Indeed, coculture of peripheral blood NK cells with 4-1BBL-expressing K562 target cells in the presence of cytochalasin D, ... cytochalasin D (E), or jasplakinolide (F) (n = 4). (G) ELISA showing concentration of CD73 protein released after 24 hours of ...
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Volume 74 Issue 2 | Acta Haematologica | Karger Publishers
Modifications in the Phagocytosis of Human Neutrophils Induced by Vinblastine and Cytochalasin B: The Effects of Lithium ... View articletitled, Modifications in the Phagocytosis of Human Neutrophils Induced by Vinblastine and Cytochalasin B: The ...
Prognostic Value of Dual-Time-Point 18F-FDG PET for Idiopathic Pulmonary Fibrosis | Journal of Nuclear Medicine
Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets | eLife
Cytochalasin D (CD) and latrunculin A (LA) are commonly-used reagents that alter the state of actin polymerization by different ... Marrow cells were treated with 1µM latrunculin A, cytochalasin D, or DMSO.. Inhibitors were either left in culture (A), or ... B) MKs or marrow cells were treated with latrunculin A or cytochalasin D for two hours. After thorough washings, cells were co- ... 1998) Disruption of actin microfilaments by cytochalasin D leads to activation of p53 FEBS Letters 430:353-357. ...