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*  CA 074|Cathepsin B inhibitor|CAS# 134448-10-5
To test the therapeutic efficacy of cysteine protease inhibitors in vivo, we treated 4T1.2 tumor -bearing mice with the ...
  http://www.apexbt.com/ca-074.html
*  CDO1 Gene - GeneCards | CDO1 Protein | CDO1 Antibody
Cysteine Dioxygenase Type 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The ... cysteine dioxygenase-1,cytosolic,expressed in liver *CDO1. UniProtKB/Swiss-Prot CatalyticActivity: L-cysteine + O(2) = 3- ... Overexpression of cysteine dioxygenase reduces intracellular cysteine and glutathione pools in HepG2/C3A cells. (PMID: 17327371 ... An insight into the mechanism of human cysteine dioxygenase. Key roles of the thioether-bonded tyrosine-cysteine cofactor. ( ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=CDO1
*  Selective Targeting of Tumor and Stromal Cells By a Nanocarrier System Displaying Lipidated Cathepsin B Inhibitor
Emerging roles of cysteine cathepsins in disease and their potential as drug targets.. Vasiljeva O, Reinheckel T, Peters C, ... Cysteine cathepsins: multifunctional enzymes in cancer.. Mohamed MM, Sloane BF., Nat. Rev. Cancer 6(10), 2006 PMID: 16990854 ... Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges.. Brix K, McInnes J, Al ... Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells.. Sobotic B, Vizovisek M, ...
  https://pub.uni-bielefeld.de/publication/2703442
*  Cysteine proteinase inhibitors and ras gene products share the same biological activities including transforming activity...
Taken together, the cysteine proteinase-specific inhibitory activity of p21 may be important for its biological activities. ... The saturation density of NIH3T3 cells was increased by repeated treatment with cysteine proteinase-specific inhibitors such as ... Because p21 transforms NIH3T3 cells and also induces differentiation of PC12 pheochromocytoma cells, several potent cysteine ... Expression of cysteine protease inhibitors in human gliomas and meningiomas. *Marupudi Sivaparvathi. , Ian McCutcheon. , ...
  https://www.semanticscholar.org/paper/Cysteine-proteinase-inhibitors-and-ras-gene-produc-Hiwasa-Sawada/5d5ed304eefcc558a24d7577f4a03c4676d40457
*  Papain Market Sees a Steady Growth Ahead - BizPR.ca | Canadian Free Press Release and Distribution Centre
Papain latex is a rich source of cysteine endopeptidases including chymopapain, caricain and glycyl endopeptidase. Papain is ...
  http://www.bizpr.ca/2017/03/21/papain-market-sees-steady-growth-ahead/
*  Collagenolytic cysteine proteinases of bone tissue. Cathepsin B, (pro)cathepsin L and a cathepsin L-like 70 kDa proteinase |...
Collagenolytic cysteine proteinases of bone tissue. Cathepsin B, (pro)cathepsin L and a cathepsin L-like 70 kDa proteinase. J M ... Collagenolytic cysteine proteinases of bone tissue. Cathepsin B, (pro)cathepsin L and a cathepsin L-like 70 kDa proteinase ... Collagenolytic cysteine proteinases of bone tissue. Cathepsin B, (pro)cathepsin L and a cathepsin L-like 70 kDa proteinase ... Collagenolytic cysteine proteinases of bone tissue. Cathepsin B, (pro)cathepsin L and a cathepsin L-like 70 kDa proteinase ...
  http://www.biochemj.org/content/279/1/167
*  "Inhibition of cathepsin B activity attenuates extracellular matrix deg" by Bernadette C. Victor, Arulselvi Anbalagan et al.
We examined expression of the cysteine protease cathepsin B and the serine protease urokinase plasminogen activator (uPA), its ... We examined expression of the cysteine protease cathepsin B and the serine protease urokinase plasminogen activator (uPA), its ...
  https://scholar.uwindsor.ca/biologypub/18/
*  Signaling pathways activated by a protease allergen in basophils. - The Kennedy Institute of Rheumatology
A cysteine protease, papain, is a prototypic protease allergen that can directly activate basophils and mast cells, leading to ... A cysteine protease, papain, is a prototypic protease allergen that can directly activate basophils and mast cells, leading to ... Cysteine Proteinase Inhibitors, Gene Expression Regulation, Immunization, Interleukin-13, Interleukin-33, Interleukin-4, ...
  https://www.kennedy.ox.ac.uk/publications/627578
*  Protocol specific for Cysteine Dioxygenase Type 1 RNAi (H00001036-R01): Novus Biologicals
Global antibody supplier and research reagent supplier to the life science community. Find antibodies and reagents all backed by our Guarantee+.
  https://www.novusbio.com/support/protocols/protocol-specific-for-cysteine-dioxygenase-type-1-rnai-h00001036-r01.html
*  中国科学院水生生物研究所机构知识库(IHB OpenIR): Identification and characterization of a cathepsin L-like cysteine protease from Taenia
Identification and characterization of a cathepsin L-like cysteine protease from Taenia solium metacestode.pdf(1186KB). --. -- ... In this study, we identified a cDNA encoding for a cathepsin L-like cysteine protease from the T solium metacestode (TsCL-1) ... In this study, we identified a cDNA encoding for a cathepsin L-like cysteine protease from the T solium metacestode (TsCL-1) ... Identification and characterization of a cathepsin L-like cysteine protease from Taenia solium metacestode.pdf ...
  http://ir.ihb.ac.cn/handle/152342/8802
*  Wholesale Amino Acid Cysteine, China Wholesale Amino Acid Cysteine Manufacturers & Suppliers | Made-in-China.com
Select 2017 high quality Wholesale Amino Acid Cysteine products in best price from certified Chinese Hyaluronic Acid Dermal ... 99% L (+) -Cysteine From China Manufacturer (CAS No: 52-90-4) FOB Price: $1 - $100 / KG Min. Order: 1 KG ... High Quality Aji L-Glutamic Acid, L-Serine, S-Carboxymethyl-L-Cysteine FOB Price: $1 - $100 / kg Min. Order: 10 kg ... Medicine Grade Cysteine for Treatment Skin Disease FOB Price: $10 - $50 / Piece Min. Order: 2 Pieces ...
  http://www.made-in-china.com/products-search/hot-china-products/Wholesale_Amino_Acid_Cysteine.html
*  Measurement of Cysteine Dioxygenase Activity and Protein Abundance - Current Protocols
... dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate 3‐sulfinoalanine ... The amount of cysteine dioxygenase may be measured by immunoblotting. Upon SDS‐PAGE, cysteine dioxygenase can be separated into ... Overexpression of cysteine dioxygenase reduces intracellular cysteine and glutathione pools in HepG2/C3A cells. Am. J. Physiol ... Regulation of cysteine dioxygenase degradation is mediated by intracellular cysteine levels and the ubiquitin‐26S proteasome ...
  http://www.currentprotocols.com/WileyCDA/CPUnit/refId-tx0615.html
*  "Lysosomal cathepsin B participates in the podosome-mediated extracellu" by Chun Tu, Ceasar F. Ortega-Cava et al.
The lysosomal cysteine cathepsins, a third major class of matrix-degrading enzymes involved in tumor invasion and tissue ... The lysosomal cysteine cathepsins, a third major class of matrix-degrading enzymes involved in tumor invasion and tissue ...
  https://scholar.uwindsor.ca/biologypub/23/
*  VackvSuG: Cys revealed that FER TYR kinase linked the CDO of two plant cells.
Many biological effects controlled by taurine biosynthetic enzymes cysteine dioxygenase (CDO) and cysteine sulfinate ... the primary metabolizing enzyme of cysteine and the regulatory point of sulfate appear to be homogeneous and cysteine of ... Cu non-specifically bound copper catalysis conversion of sulfite to sulfate* via sulfite oxidase (SO) was begun by cysteine ... Kinetic studies of mutant CDOs reveal that the cysteine residue. The structural biology exist and instead adopts the first step ...
  http://lnwme.blogspot.com/2009/10/cys-revealed-that-fer-tyr-kinase-linked.html
*  Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin
Non-Invasive Imaging of Cysteine Cathepsin Activity in Solid Tumors Using a 64Cu-Labeled Activity-Based Probe. PloS one. 2011;6 ... Prognostic value of the cysteine proteases cathepsins B and cathepsin L in human breast cancer. Clinical cancer research. 1995; ... Cysteine cathepsins: from structure, function and regulation to new frontiers. Biochimica et biophysica acta. 2012;1824:68-88 ... Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response. Nature reviews Cancer. 2015;15:712-29 ...
  http://thno.org/v07p2806.htm
*  Cystatin - Wikipedia
The cystatins are a family of cysteine protease inhibitors which share a sequence homology and a common tertiary structure of ... Machleidt W, Borchart U, Fritz H, Brzin J, Ritonja A, Turk V (November 1983). "Protein inhibitors of cysteine proteinases. II. ... van Wyk SG, Du Plessis M, Cullis CA, Kunert KJ, Vorster BJ (November 2014). "cysteine protease and cystatin expression and ... found some 19 different cystatins similar to oryzacystatin-I in the soybean along with related cysteine proteases. Chicken ...
  https://en.wikipedia.org/wiki/Cystatin
*  Papain - Wikipedia
"Novel cysteine proteinase inhibitors homologous to the proregions of cysteine proteinases". Curr Protein Pept Sci. 3 (2): 231- ... This cysteine then performs a nucleophilic attack on the carbonyl carbon of a peptide backbone. This forms a covalent acyl- ... Papain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme present in papaya (Carica papaya) and ... The mechanism by which papain breaks peptide bonds involves the use of a catalytic triad with a deprotonated cysteine. Asn-175 ...
  https://en.wikipedia.org/wiki/Papain
*  Cysteine - Wikipedia
"cysteine - Definition of cysteine in English by Oxford Dictionaries". Oxford Dictionaries - English. Retrieved 15 April 2018.. ... Cysteine (symbol Cys or C;[3] /ˈsɪstiiːn/)[4] is a semi-essential[5] proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH ... For example, the reaction of cysteine with sugars in a Maillard reaction yields meat flavors.[25] L-Cysteine is also used as a ... N-Acetyl-L-cysteine is a derivative of cysteine wherein an acetyl group is attached to the nitrogen atom. This compound is sold ...
  https://en.wikipedia.org/wiki/L-cysteine
*  L-Cysteine
Other names: Cysteine, L-; «beta»-Mercaptoalanine; Cystein; Cysteine; Half-cystine; L-(+)-Cysteine; L-Alanine, 3-mercapto-; NSC ...
  https://webbook.nist.gov/cgi/inchi/InChI%3D1S/C3H7NO2S/c4-2
*  L-Cysteine
Other names: Cysteine, L-; «beta»-Mercaptoalanine; Cystein; Cysteine; Half-cystine; L-(+)-Cysteine; L-Alanine, 3-mercapto-; NSC ... On the character of the cyclic ionic H-bond in cryogenically cooled deprotonated cysteine, Phys. Chem. Chem. Phys., 2014, 16, ... and computations on cysteine and its conjugate base, J. Am. Chem. Soc., 2007, 129, 17, 5403-5407, https://doi.org/10.1021/ ...
  https://webbook.nist.gov/cgi/inchi?ID=C52904&Mask=8
*  Cysteine | Define Cysteine at Dictionary.com
Cysteine definition, a crystalline amino acid, C 3 H 7 O 2 NS, a component of nearly all proteins, obtained by the reduction of ... cysteine in Medicine Expand. cysteine cys·te·ine (sĭs'tē-ēn', -ĭn, sĭ-stē'ĭn). n. Abbr. Cys An alpha-amino acid found in most ... Eggs, he says, are a good source of cysteine, an amino acid that helps the liver break down alcohol faster. ...
  http://www.dictionary.com/browse/cysteine
*  Cysteine proteinase (P05993) | InterPro | EMBL-EBI
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
  http://www.ebi.ac.uk/interpro/protein/P05993
*  N-acetyl-L-cysteine (CHEBI:28939)
... is a N-acetyl-L-amino acid (CHEBI:21545) N-acetyl-L-cysteine (CHEBI:28939) is a L-cysteine ... N-acetyl-L-cysteine (CHEBI:28939) is a acetylcysteine (CHEBI:22198) N-acetyl-L-cysteine (CHEBI:28939) is conjugate acid of N- ... S-substituted N-acetyl-L-cysteine (CHEBI:47911) has functional parent N-acetyl-L-cysteine (CHEBI:28939). N-acetyl-L-cysteinate ... N-acetyl-L-cysteine (CHEBI:28939) has role antiviral drug (CHEBI:36044) N-acetyl-L-cysteine (CHEBI:28939) has role human ...
  https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:21548
*  DSpace@MIT: Cysteine arylation
For decades, cysteine-based reactions with maleimides and alkyl halides are the primary methods for selectively tagging ... These cysteine arylation reactions are applied to the synthesis of macrocyclic peptides and antibody-drug conjugates (ADCs). ... The goal of this thesis is to develop new cysteine arylation reactions to generate sulfur-sp² carbon bonds on proteins. These ... These traditional reactions generate sulfur-sp³ carbon bonds between the cysteine thiol and the labeling reagents. ...
  http://dspace.mit.edu/handle/1721.1/112448
*  Amino Acids: Cysteine and Cystine
Cysteine and Cystine are sulfur-containing amino acids that are synthesized in the liver and are involved in multiple metabolic ... Cysteine can be converted to cystine and taurine. Cystine itself is a disulfide, containing two cysteine molecules. Cysteine is ... L-cysteine also forms another amino acid, L-cystine, which is important in hair and nail tissues. L-cysteine supplementation ... POSSIBLE USES OF L-CYSTEINE. Smokers*. Smoker's cough/bronchitis. Air pollution. Exposure to chemicals. Psoriasis (aids skin ...
  http://www.healthy.net/Health/Article/Cysteine_and_Cystine/1942