*  Acanthosicyos horridus (PROTA) - PlantUse English
Cucurbitacins B and D have been identified as the primary source of bitterness, together with traces of cucurbitacins G and H. ... The same four cucurbitacins are found in higher concentrations in the dried root. The bitter principles occur as aglycones in ... Cucurbitacins from Acanthosicyos horridus. Phytochemistry 25(7): 1681-1684.. * Jeffrey, C., 1980. A review of the Cucurbitaceae ... The LD50 of cucurbitacin B administered intraperitoneally to mice is 1 mg/kg, and this dose produces pulmonary oedema. The ...
  http://uses.plantnet-project.org/en/Acanthosicyos_horridus_
*  Creamy Cucumber Salad | We Grow
At the top of the phytonutrient list for cucumbers are its cucurbitacins, lignans, and flavonoids. These three types of ...
  http://wegrowfoods.com/creamy-cucumber-salad/
*  Scientific findings : THIS FRUIT KILLS DIABETES AND STOPS BREAST CANCER CELLS FROM GROWING AND SPREADING - Mr. Healthy...
Bitter melon contains alkaloids, glycoside, peptides, acids, cucurbitins, charantin, cucurbitacins, momordine,.... Naum Joveski ... Bitter melon contains alkaloids, glycoside, peptides, acids, cucurbitins, charantin, cucurbitacins, momordine, momorcharins, ...
  http://mrhealthyalternative.com/2016/09/18/scientific-findings-fruit-kills-diabetes-stops-breast-cancer-cells-growing-spreading/
*  Drink This Juice For Glowing Skin! - mindbodygreen
At the top of the phytonutrient list for cucumbers are its cucurbitacins, lignans, and flavonoids. These three types of ...
  https://www.mindbodygreen.com/0-14205/drink-this-juice-for-glowing-skin.html
*  Cucurbitacin - Wikipedia
Cucurbitacin S[edit]. *Cucurbitacin S from Bryonia dioica [1]:84'85. Cucurbitacin T[edit]. *Cucurbitacin T, from the fruits of ... Cucurbitacin K[edit]. *Cucurbitacin K, stereoisomer of cucurbitacin J,[9]:2 from Iberis amara [1]:70 *Cucurbitacin K 2-O-β- ... Cucurbitacin O[edit]. *Cucurbitacin O from Brandegea bigelovii [1]:73 *Cucurbitacin Q 2-O-glucoside, from Picrorhiza kurrooa [1 ... Cucurbitacin J[edit]. *Cucurbitacin J from Iberis amara [1]:69 *Cucurbitacin J 2-O-β-glucopyranoside from Trichosanthes ...
  https://en.wikipedia.org/wiki/Cucurbitacin
*  cucurbitacins Pesticide Petition Filing 8/99
Cucurbitacin I is the most toxic. The LD,INF,50,/INF, of cucurbitacin E-glycoside, one of the more effective insect feeding ... Most cucurbitacins are insoluble in water and transfer of these cucurbitacins to ground water is unlikely. The glycosylated ... The cucurbitacins occur in nature in mixtures. Cucurbitacin B [25-(acetyloxy)-2,16,20- trihydroxy-9-methyl-19-norlanosta- 5,23- ... Cucurbitacins from the buffalo gourd and zucchini squash are currently used in pesticide products. Cucurbitacins are oxygenated ...
  http://pmep.cce.cornell.edu/profiles/miscpesticides/alphaalkyl-metaldehyde/cucurbitacins/cucurbaticins_pet_899.html
*  Cucurbitacin E Has Neuroprotective Properties and Autophagic Modulating Activities on Dopaminergic Neurons
... Anne-Marie Arel- ... Anne-Marie Arel-Dubeau, Fanny Longpré, Julie Bournival, et al., "Cucurbitacin E Has Neuroprotective Properties and Autophagic ...
  https://www.hindawi.com/journals/omcl/2014/425496/cta/
*  Cucurbitacin E Has Neuroprotective Properties and Autophagic Modulating Activities on Dopaminergic Neurons
... Anne-Marie Arel- ... We evaluated the neuroprotective potential of cucurbitacin E (CuE), a tetracyclic triterpenoid phytosterol extracted from the ...
  https://www.hindawi.com/journals/omcl/2014/425496/abs/
*  cucurbitacin - oi
Cucurbitacins as Feeding and Oviposition Deterrents to Insects 496PAlterations of cellular proliferation, apoptosis and ... Cucurbitacin E suppresses cytokine expression in human Jurkat T cells through down-regulating the NF-κB signaling ... Cucurbitacin B induces rapid depletion of the G-actin pool through reactive oxygen species-dependent actin aggregation in ... Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal ...
  http://oxfordindex.oup.com/view/10.1093/oi/authority.20110803095652176
*  Cucurbitacin E - Wikipedia
Cucurbitacin E is a biochemical compound from the family of cucurbitacins. These are found in plants which are member of the ... Specific changes on this molecule under certain conditions can generate other types of cucurbitacins such as cucurbitacin I, J ... Cucurbitacin E inhibits the adhesion of cancer cells in type I collagen . Cucurbitacin-E protects hepatocytes from CCl4 (carbon ... Cucurbitacin E is an important inhibitor during the S to M phase in the cell mitosis. It causes a reduction of cell ...
  https://en.wikipedia.org/wiki/Cucurbitacin_E
*  Cucurbitacin D - Wikipedia
Cucurbitacin D is a plant steroid with anticancer activity. Cucurbitacin D induces growth inhibition, cell cycle arrest, and ...
  https://en.wikipedia.org/wiki/Cucurbitacin_D
*  Cucurbitacin Delta23-reductase - Wikipedia
In enzymology, a cucurbitacin Delta23-reductase (EC 1.3.1.5) is an enzyme that catalyzes the chemical reaction 23,24- ... This enzyme is also called NAD(P)H: cucurbitacin B Delta23-oxidoreductase. It employs one cofactor, manganese. Schabort JC, ... Schabort JC, Potgieter DJ, de Villiers V (1968). "Cucurbitacin B delta 23-reductase from Cucurbita maxima. I. Assay methods, ... Potgieter DJ (1968). "Cucurbitacin B delta 23-reductase from Cucurbita maxima. II Cofactor requirements, enzyme kinetics, ...
  https://en.wikipedia.org/wiki/Cucurbitacin_Delta23-reductase
*  Cucurbitacin L 2-O-β-Glucoside Demonstrates Apoptogenesis in Colon Adenocarcinoma Cells (HT-29): Involvement of Reactive Oxygen...
... and cucurbitacin Q; a highly selective inhibitor of JAK2 activation, cucurbitacin A; three dual inhibitors, cucurbitacin I, E, ... Isolation of Cucurbitacin L 2-O-β-Glucoside. Citrullus latanus var. citriode was collected from AL-Musawwarat area, Northern ... Cucurbitacin L 2-O-β-Glucoside Demonstrates Apoptogenesis in Colon Adenocarcinoma Cells (HT-29): Involvement of Reactive Oxygen ... The current study was designed to investigate the anti-ROS and -RNS effects of cucurbitacin L 2-O-β-glucoside (CLG) and the ...
  https://www.hindawi.com/journals/ecam/2012/490136/
*  The Anti-Melanoma Efficiency of the Intratumoral Injection of Cucurbitacin-Loaded Sustained Release Carriers: In Situ-Forming...
Our previous studies revealed that the PLGA-based particulate systems loaded with cucurbitacin showed limited anti-melanoma ... anti-melanoma efficiency cucurbitacin drug release in situ-forming implants (ISFIs) intratumoral injection ... The Anti-Melanoma Efficiency of the Intratumoral Injection of Cucurbitacin-Loaded Sustained Release Carriers: In Situ-Forming ... Our previous studies revealed that the PLGA-based particulate systems loaded with cucurbitacin showed limited anti-melanoma ...
  https://rd.springer.com/article/10.1208/s12249-015-0292-2
*  Comparison between the effects of potassium phosphite and chitosan on changes in the concentration of Cucurbitacin E and on...
The aim of this study was to investigate the effect of potassium phosphite (KPhi) and chitosan on Cucurbitacin E (CuE) ... Cucurbitacins are mostly found in the members of the family Cucurbitaceae and are responsible for the bitter taste of cucumber ... Seeds exhibit very low concentration of cucurbitacins [2]. The diversity of cucurbitacins lies in side chain derivatives that ... Cucumis sativus belongs to Cucurbitaceae family and is known to be rich in cucurbitacins. Cucurbitacins have become interesting ...
  https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-017-1808-y
*  IDEALS @ Illinois: Disposition of Cucurbitacin as a Factor in Host Plant Selection by Diabroticite Beetles and Electrophoretic...
beetles fed on squash fruit containing cucurbitacins were rejected. Moreover, even when adults did not feed on cucurbitacins, ... fruit devoid of cucurbitacins). The longevity of female A. vittatum, however, was unaffected by the presence or absence of ... Disposition of Cucurbitacin as a Factor in Host Plant Selection by Diabroticite Beetles and Electrophoretic Analysis of the ... Disposition of Cucurbitacin as a Factor in Host Plant Selection by Diabroticite Beetles and Electrophoretic Analysis of the ...
  https://www.ideals.illinois.edu/handle/2142/71776
*  Plus it
Cucurbitacin I also failed to affect the activation of P-Rex1 by heregulin. Subsequent analysis revealed that cucurbitacin I ... Cucurbitacin I Inhibits Rac1 Activation in Breast Cancer Cells by a Ros-Mediated Mechanism and Independently of Jak2 and P-Rex1 ... Cucurbitacin I Inhibits Rac1 Activation in Breast Cancer Cells by a Ros-Mediated Mechanism and Independently of Jak2 and P-Rex1 ... Cucurbitacin I Inhibits Rac1 Activation in Breast Cancer Cells by a Ros-Mediated Mechanism and Independently of Jak2 and P-Rex1 ...
  http://molpharm.aspetjournals.org/content/early/2013/03/11/mol.112.084293
*  Cucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B Leukemic...
Cucurbitacin-I (JSI-124) is potent inhibitor of JAK/STAT3 signaling pathway and has anti-tumor activity in a variety of cancer ... Cucurbitacin-I (JSI-124) can be found in a variety of plants that have been used for centuries as folk medicines in Asia [1-3 ... Cucurbitacin-I (JSI-124) is potent inhibitor of JAK/STAT3 signaling pathway and has anti-tumor activity in a variety of cancer ... Cucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B Leukemic ...
  https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-11-268
*  Insecticidal Effect of Cucurbitacin E Glycoside Isolated from Citrullus colocynthis Against Aphis craccivora
... H.M., Torkey,; H. ... Insecticidal Effect of Cucurbitacin E Glycoside Isolated from Citrullus colocynthis Against Aphis craccivora. Login ...
  http://dspace.must.edu.eg/handle/123456789/215
*  Synergistic effect of cucurbitacin B in combination with curcumin via enhancing apoptosis induction and reversing multidrug...
Synergistic effect of cucurbitacin B in combination with curcumin via enhancing apoptosis induction and reversing multidrug ... In conclusion, cucurbitacin B in the combination with curcumin could serve as a novel, promising approach for human hepatoma.. ... Cucurbitacin B is a plant-derived tetracyclic triterpenoid, which has been used for a variety of cancers, especially human ... In the present study, the synergistic effect of cucurbitacin B and curcumin was studied on BEL7402/5-Fu cells in vitro and ...
  http://bioremede.com/logy/2015/11/21/synergistic-effect-of-cucurbitacin-b-in-combination-with-curcumin-via-enhancing-apoptosis-induction-and-reversing-multidrug-resistance-in-human-hepatoma-cells/
*  New Products
Cucurbitacin I Cucurbitacin I, Cucumis sativus L. has been found to suppress levels of phosphotyrosine Stat3 (signal transducer ... Cucurbitacin IIb Cucurbitacin Iib, extracted from Hemsleya amabilis Diels root tuber. A15406. Cucurbitacin S Cucurbitacin S, ...
  http://www.adooq.com/new-products
*  Angiogenesis Inhibitors | GreenMedInfo | Pharmacological Action
Cucurbitacin B inhibited the metastatic abilities of NSCLC through the inhibition of Wnt/β-catenin signaling axis.Dec 31, 2015 ... Cucurbitacin B inhibits α5β1 integrin-mediated adhesion, migration, proliferation of human glioblastoma cell line.Feb 14, 2017 ...
  http://www.greenmedinfo.com/pharmacological-action/angiogenesis-inhibitors
*  Ramon Enrique Robles Zepeda - Mendeley
Antiproliferative and apoptosis induction of cucurbitacin-type triterpenes from Ibervillea sonorae. *Torres-Moreno H ...
  https://www.mendeley.com/profiles/ramon-enrique-robles-zepeda/
*  Cucurbitales
Chemistry, Morphology, etc. For cucurbitacins, some of which affect microtubule development and mitosis, see X. Wang et al. ( ... Indeed, the concentration of cucurbitacins inside and outside the trench is about the same, but the sap is very rich in P- ... Trees, (deciduous); ?cucurbitacins, tannin 0; (wood fluorescing); (nodes with 2 traces from the lateral gaps); hairs glandular ... However, at least some of these beetles will eat cucurbitacin crystals neat, so physical avoidance of the copious sap produced ...
  http://www.mobot.org/mobot/research/APWeb/orders/cucurbitalesweb.htm