... and restoration of GJC by forced expression of connexins reduces indice … ... are formed by assembly of trans-membrane connexin proteins and have multiple functions including the coordination of cell ... and restoration of GJC by forced expression of connexins reduces indices of neoplasia. Expression of connexin 43 (Cx43), the ... Transcriptional regulation of connexin 43 expression by retinoids and carotenoids: similarities and differences Mol Carcinog. ...
connexin, Cx43, gap junction, migration, p38MAPK. Subjects:. 500 Natural sciences and mathematics. 500 Natural sciences and ... A channel independent function of connexin 43 in cell migration A channel independent function of connexin 43 in cell migration ... Behrens, Juliane (2011): A channel independent function of connexin 43 in cell migration. Dissertation, LMU München: Faculty of ...
Connexin 43 (Cx43) is a particularly important connexin to gap junctional communication and could act either to preserve the ... of two connexon hemichannels from the two communicating cells and these connexons themselves are composed of six connexin ... Connexin 43 (Cx43) is a particularly important connexin to gap junctional communication and could act either to preserve the ... Connexin-43 and Traumatic Brain Injury: A potential target for therapeutic intervention ...
We chose to focus on these two proteins out of the five connexins (Cx26, 43, 40, 37, and 45) which we found by RT-PCR to be ... Connexins 43 and 26 are differentially increased after rat bladder outlet obstruction. In: Experimental cell research, 2002, ... To evaluate whether these connexins are affected by changes in transmural urine pressure, we used a rat model of bladder outlet ... To evaluate the regulation of connexin expression by fluid pressure, we have studied the effects of elevated transmural urine ...
Connexins are commonly named according to their molecular weights, e.g. Cx26 is the connexin protein of 26 kDa. A competing ... Media related to connexins at Wikimedia Commons Connexins at the U.S. National Library of Medicine Medical Subject Headings ( ... Kamasawa N, Sik A, Morita M, Yasumura T, Davidson KG, Nagy JI, Rash JE (2005). "Connexin-47 and connexin-32 in gap junctions of ... As of this edit, this article uses content from "1.A.24 The Gap Junction-forming Connexin (Connexin) Family", which is licensed ...
Probing Endothelial Cell Mechanics through Connexin 43 Disruption *M. M. Islam. *R. L. Steward ... These two modes of stimulation have previously been shown to produce distinct cellular responses34,43. FN distribution in cells ...
Mouse CX43(Connexin 43) ELISA Kit. To Order Contact us below: [email protected] ... Description: A sandwich ELISA kit for detection of Connexin 43 from Mouse in samples from blood, serum, plasma, cell culture ... Description: A sandwich ELISA kit for quantitative measurement of Mouse CX43 (Connexin 43) in samples from Serum, Plasma, Cell ... Description: A sandwich quantitative ELISA assay kit for detection of Rat Connexin 43 (CX43) in samples from tissue homogenates ...
keywords = "Connexin 43, Energy metabolism, Hypothalamus, NAD, Supplement",. author = "Eun Roh and Park, {Jae Woo} and Kang, { ... Exogenous nicotinamide adenine dinucleotide regulates energy metabolism via hypothalamic connexin 43. Eun Roh, Jae Woo Park, ... Extracellular NAD was imported into N1 hypothalamic neuronal cells in a connexin 43-dependent and CD73-independent manner. ... Consistent with the in vitro data, inhibition of hypothalamic connexin 43 blocked hypothalamic NAD uptake and NAD-induced ...
Glial connexin 43 hemichannels (Cx43 HCs) enable direct exchange with the extracellular space and can regulate neuronal network ... Blockade of Glial Connexin 43 Hemichannels Reduces Food Intake. http://api.archives-ouvertes.fr/search/?fq=halId_s:hal-03037294 ...
Connexin protein monomers complex to form gap junction intercellular channels between various communicating cell types Connexin ... β-glycyrrhetinic acid alters expression and phosphorylation of the gap junction protein connexin-43 in enterocyte-like cells. ... 43 is the major connexin expressed in intestinal epithelial cells in culture (R.B. & M.K., unpublished) β-glycyrrhetinic acid ...
Dive into the research topics of Novel pharmacophores of connexin43 based on the "rxp" series of Cx43-binding peptides. ... Novel pharmacophores of connexin43 based on the "rxp" series of Cx43-binding peptides. ...
Western blot analysis showed that connexin 43 (Cx43), which is the major functional protein of gap junction, is present in ... Western blot analysis showed that connexin 43 (Cx43), which is the major functional protein of gap junction, is present in ... Western blot analysis showed that connexin 43 (Cx43), which is the major functional protein of gap junction, is present in ... Western blot analysis showed that connexin 43 (Cx43), which is the major functional protein of gap junction, is present in ...
Connexin43 (Cx43) is the most abundant connexin isoform and is found in the working myocardium of the atrium and ventricle as ... Connexin hemichannels: methods for dye uptake and leakage. J Membr Biol. 2016;249(6):713-741.. View this article via: PubMed ... Therapeutic strategies targeting connexins. Nat Rev Drug Discov. 2018;17(12):905-921.. View this article via: PubMed CrossRef ... The effects of connexin phosphorylation on gap junctional communication. Int J Biochem Cell Biol. 2004;36(7):1171-1186.. View ...
Profundice en los temas de investigación de Mechanosensitive piezo1 calcium channel activates connexin 43 hemichannels through ... Mechanosensitive piezo1 calcium channel activates connexin 43 hemichannels through PI3K signaling pathway in bone. ...
Dive into the research topics of Cardiotoxic effects of short-term doxorubicin administration: Involvement of connexin 43 in ... Cardiotoxic effects of short-term doxorubicin administration: Involvement of connexin 43 in calcium impairment. ...
Connexin 43 plays an important role in the transformation of cholangiocytes with Clonochis sinensis excretory-secretory protein ... Connexin 43 plays an important role in the transformation of cholangiocytes with Clonochis sinensis excretory-secretory protein ... YUHSpace: Connexin 43 plays an important role in the transformation of cholangiocytes with Clonochis sinensis excretory- ... The gap-junction proteins connexin (Cx) 43 and Cx26 increased. In contrast, Cx32 expression decreased in cells treated with ...
The uniform distribution of connexin 43 on the cell membrane of MICs, rather than localisation in gap junction plaques, may ... Myometrial smooth myocytes from term uterine biopsies expressed connexin 43 in a punctate pattern typical of gap junctions. ... Immunohistochemistry using an antibody directed against connexin 43 unphosphorylated at serine 368 showed that it is this ... Double-stain immunofluorescence for unphosphorylated connexin 43 and KIT, an established marker for interstitial cells, ...
While this pathway is well-described in the literature, Sheng says they are the first to identify connexin 43s role in ... "To me, the most novel finding in this study is that we discovered connexin 43 selectively binds to the PIK3CB/p110beta protein ... In previous studies of gliomas, increased levels of the connexin 43 protein suppressed tumor growth. But in more aggressive ... The researchers described the positive effects of inhibiting connexin 43 activityin their2015 study published in Cancer Re ...
Increased expression of connexin 43. [86]. Chitosan-modified Au NPs. Chitosan. Crosslinking of the hydrogel in NPs/polymer ... You, J.-O.; Rafat, M.; Ye, G.J.C.; Auguste, D.T. Nanoengineering the Heart: Conductive Scaffolds Enhance Connexin 43 Expression ... In addition, there was a higher expression level of connexin 43 and higher synchronized contractile frequency compared to the ... The neonatal rat cardiomyocytes seeded on the scaffold showed enhanced proliferation, and increased the level of connexin-43 in ...
Connexin 43. +. +. +. Cytokeratin 15. +. +. +. +=moderate to high expression; +/−=low to moderate expression; -=no expression ...
Husøy, T., Cruciani, V., Sanner, T., & Mikalsen, S-O. (2001). Phosphorylation of connexin43 and inhibition of gap junctional ... Phosphorylation of connexin43 and inhibition of gap junctional communication in 12-O-tetradecanoylphorbol-13-acetate-exposed R6 ... Phosphorylation of connexin43 and inhibition of gap junctional communication in 12-O-tetradecanoylphorbol-13-acetate-exposed R6 ... Husøy, T, Cruciani, V, Sanner, T & Mikalsen, S-O 2001, Phosphorylation of connexin43 and inhibition of gap junctional ...
... and reduced connexin43-positive gap junctions, but concomitant electrical pacing increases connexin43-positive gap junctions in ... Cardiac cell therapy with mesenchymal stem cell induces cardiac nerve sprouting, angiogenesis, and reduced connexin43-positive ... gap junctions, but concomitant electrical pacing increases connexin43-positive gap junctions in canine heart. ...
The treatment with trandolapril and losartan attenuates pressure and volume overload alternations of cardiac connexin-43 and ...
connexin 31.5 0 *Connexins. J Exp Biol 2000 Nov;203 Pt 21:3299-306 connexin 36 0 *Connexins. Gene 2000 Jun 27;251(2):123-30 ... connexin 44 0 *Connexins. J Membr Biol 2001 May 1;181(1):21-30 connexin 47 0 *Connexins Gap Junctions. J Neurosci 2001 Feb 15; ... connexin 30.2, mouse 0 *Connexins. FEBS Lett 2003 Apr 10;540(1-3):151-6 connexin 30, rat 0 *Connexins. Cell Tissue Res 1998 Dec ... connexin 41, Xenopus 0 *Connexins *Xenopus Proteins. Mol Reprod Dev 1995 Sep;42(1):7-18 connexin 26 127120-53-0 *Connexins. ...
Connexin 26 and Connexin 43 in Canine Mammary Carcinoma. Journals. Active Journals Find a Journal Proceedings Series ...
... expression of the gap junction protein Connexin43 within the lesion area in order to reduce post-infarct ventricular ... Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia. Nature 450: 819-824. ...
Other markers were enriched in GLT1+ cells between 8.9-fold (Gja1, Connexin-43) and 297.2-fold (Slc1a2, GLT1). Sox9 enrichment ... 2011) Dysfunction of astrocyte connexins 30 and 43 in dorsal lateral prefrontal cortex of suicide completers. Biol Psychiatry ... co-localization with connexin43 at gap junctions and late developmental appearance. Neuroscience 88:447-468. doi:10.1016/S0306- ... connexin-30 (Cx30) (Nagy et al., 1999), and, more recently, aldehyde dehydrogenase 1 family member L1 (ALDH1L1) (Cahoy et al., ...
Herein, we revised literature on connexins, the core gap junction forming proteins, and WT1, a transcription factor involved ... Connexin 43 and Sonic Hedgehog Pathway Interplay in Glioblastoma Cell Proliferation and Migration ... Mu and Delta Opioid Receptor Targeting Reduces Connexin 43-Based Heterocellular Coupling during Neuropathic Pain ... FROM PHYSIOLOGICAL TO NEOPLASTIC TRANSFORMATION: THE CRITICAL ROLES OF CONNEXINS AND WT1 ...
Connexin 43-mediated mitochondrial transfer of iPSC-MSCs alleviates asthma inflammation. Stem Cell Reports. (2018) 11:1120-35. ... Some studies have demonstrated that gap junction protein connexin 43 (CX43) is necessary for TNTs formation and TNT-mediated ... 43. French KC, Antonyak MA, Cerione RA. Extracellular vesicle docking at the cellular port: extracellular vesicle binding and ... J Thorac Cardiovasc Surg. (2017) 153:934-43. doi: 10.1016/j.jtcvs.2016.10.077 ...