*  C4bp complement protein - Semantic Scholar
It binds as a cofactor to COMPLEMENT FACTOR I which then hydrolyzes the COMPLEMENT C4B in the CLASSICAL PATHWAY C3 CONVERTASE ( ... A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. ... C4bp complement protein. Known as: C4bC3bINA Cofactor, Complement C3b C4b Inactivator Cofactor, Protein, Complement C4b-Binding ... A serum protein that regulates the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It binds as a cofactor to COMPLEMENT FACTOR I which ...
  https://www.semanticscholar.org/topic/C4bp-complement-protein/1286503
*  Atypical haemolytic uraemic syndrome and mutations in complement regulator genes | SpringerLink
Pangburn MK, Schreiber RD, Muller-Eberhard HJ (1977) Human complement C3b inactivator: isolation, characterization, and ... Disulfide bonds are localized within the short consensus repeat units of complement regulatory proteins: C4b-binding protein. ... Weis JH, Morton CC, Bruns GA et al (1987) A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr ... Wiedmer T, Sims PJ (1991) Participation of protein kinases in complement C5b-9-induced shedding of platelet plasma membrane ...
  https://link.springer.com/article/10.1007%2Fs00281-005-0003-2
*  Complement factor I - Wikipedia
Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. Complement ... is a protein of the complement system, first isolated in 1966 in guinea pig serum, that regulates complement activation by ... Maga TK, Nishimura CJ, Weaver AE, Frees KL, Smith RJ (Jun 2010). "Mutations in alternative pathway complement proteins in ... Nakamura S, Abe K (1985). "Genetic polymorphism of human factor I (C3b inactivator)". Human Genetics. 71 (1): 45-8. doi:10.1007 ...
  https://en.wikipedia.org/wiki/Complement_factor_I
*  Alternative complement pathway - Wikipedia
Factor I requires a C3b-binding protein cofactor such as complement factor H, CR1, or Membrane Cofactor of Proteolysis (MCP or ... Pangburn MK, Schreiber RD, Müller-Eberhard HJ (July 1977). "Human complement C3b inactivator: isolation, characterization, and ... cells from complement-mediated damage. CFHR5 (Complement Factor H-Related protein 5) is able to bind to act as a cofactor for ... Since C3b is free and abundant in the plasma, it can bind to either a host cell or a pathogen surface. To prevent complement ...
  https://en.wikipedia.org/wiki/Alternative_complement_pathway
*  Frontiers | Defining the Binding Region in Factor H to Develop a Therapeutic Factor H-Fc Fusion Protein against Non-Typeable...
FH18-20/Fc bound weakly to three of the strains but did not promote complement dependent killing. Outer-membrane protein P5 has ... FH18-20/Fc bound weakly to three of the strains but did not promote complement dependent killing. Outer-membrane protein P5 has ... Chimeric proteins containing the regions that most FH-binding bacteria use to engage human FH, domains 6 and 7 (FH6,7/Fc) and/ ... Chimeric proteins containing the regions that most FH-binding bacteria use to engage human FH, domains 6 and 7 (FH6,7/Fc) and/ ...
  https://www.frontiersin.org/articles/10.3389/fcimb.2016.00040/full
*  Mouse Anti-Human Complement C4c Clone 99-72-18 mAb | Cell Sciences
... a component in the complement cascade and a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and ... p,The mouse monoclonal antibody recognizes human Complement component 4 c (C4c), ... The C4 protein derives from the C4A-C4B genes.. ELISA: This antibody may be used as a capture antibody in combination with ... a component in the complement cascade and a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and ...
  https://www.cellsciences.com/mouse-anti-human-complement-c4c-clone-99-72-18-mab
*  List of MeSH codes (D12.776.124) - Wikipedia
... complement c3b inactivator proteins MeSH D12.776.124.486.274.920.325.200 -- complement factor h MeSH D12.776.124.486.274.920. ... complement c1 inactivator proteins MeSH D12.776.124.486.274.920.250.500 -- complement c1 inhibitor protein MeSH D12.776.124.486 ... complement factor b MeSH D12.776.124.486.274.920 -- complement inactivator proteins MeSH D12.776.124.486.274.920.124 -- ... complement c3a MeSH D12.776.124.486.274.250.260 -- complement c3b MeSH D12.776.124.486.274.250.260.500 -- complement c3c MeSH ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.124)
*  Skin Injuries Reduce Survival and Modulate Corticosterone, C-Reactive Protein, Complement Component 3, IgM, and Prostaglandin...
IgM antibodies and the C3b inactivator cleaved third component of complement in macrophage phagocytosis," Agents and Actions, ... C-reactive protein (CRP) is a general stress-response protein, which is produced in response to inflammation. Complement ... Herein, the IL-6-induced stress proteins including C-reactive protein (CRP), complement 3 (C3), immunoglobulin M (IgM), and ... IgM antibodies appear early in the course of an infection activating complement and causing C3b to bind to the antigen [27]. In ...
  https://www.hindawi.com/journals/omcl/2013/821541/
*  C3-convertase - Wikipedia
C4b-binding protein inhibits the haemolytic function of cell-bound C4b. C4b-binding protein and C3b inactivator control the C3 ... C3 convertase (EC 3.4.21.43, C42 , C4bC2b, C3bBb, complement C.hivin.4.hivin2, complement C3 convertase) belongs to family of ... "Modulation of the Classical Pathway C3 Convertase by Plasma Proteins C4 Binding Protein and C3b Inactivator". Proc Natl Acad ... in addition to enhancing proteolytic inactivation of C3b by C3b inactivator (C3bINA - endopeptidase). Membrane-associated ...
  https://en.wikipedia.org/wiki/C3-convertase
*  CFI Gene - GeneCards | CFAI Protein | CFAI Antibody
Protein Coding), Complement Factor I, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards ... Cloning and characterization of the promoter for the human complement factor I (C3b/C4b inactivator) gene. (PMID: 9479036) ... Protein Symbol:. P05156-CFAI_HUMAN. Recommended name:. Complement factor I Protein Accession:. P05156. Secondary Accessions: * ... CFI (Complement Factor I) is a Protein Coding gene. Diseases associated with CFI include Complement Factor I Deficiency and ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=CFI
*  System, devices, and methods for real-time monitoring of cerebrospinal fluid for markers of progressive conditions - Patent...
C3b-inactivator, C4 binding protein, C4 component, C4a component, C4-binding protein, C5 component, C5a component, C6 component ... complement components, coagulation factors, coagulation proteins, complement components, c-peptide, c-reactive protein, ... proteins (e.g., 14-3-3 protein, glial fibrillary acid protein (GFAP), myelin basic protein (MBP), neurofilament (NFL), neuron- ... phospho-tau protein, S100 calcium binding protein B, synaptosome-associated protein (SNAP-25), tau protein, thyrotropin- ...
  http://www.patentsencyclopedia.com/app/20120238837
*  Anti-CFI / Complement Factor I Antibody (Internal) - Rabbit Anti Human Polyclonal Antibody WB, IHC-P - Buy Now! |Abgent
Complement Factor I Antibody (Internal), Rabbit Anti Human Polyclonal Antibody validated in WB, IHC-P (ALS17749), Abgent ... CFI, AHUS3, C3BINA, C3b-inactivator, C3B/C4B inactivator, Complement component I, Complement component factor i, Factor I, FI, ... Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H ... KAF, I factor, I factor (complement), C3b-INA, Complement factor I, Light chain of factor I. ...
  http://www.abgent.com/products/ALS17749-Anti-CFI--Complement-Factor-I-Antibody-Internal
*  C4BPA抗体|Abcam中国|Anti-C4BPA抗体(ab121123)
It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates ... The Universal Protein Resource (UniProt) in 2010. Nucleic Acids Res. 38:D142-D148 (2010) . ... It interacts also with anticoagulant protein S and with serum amyloid P component. ... the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. ...
  http://www.abcam.cn/c4bpa-antibody-ab121123.html
*  Cellufine Sulphate | amsbio
Complement C3, C9. *Complement C1, C3b. Inactivators. *IgG. *Ceruloplasmin. *α2-Macroglobulin. *RNase ... Protein Purification Cellufine Sulfate mimics the affinity of heparin or dextran sulfate for many proteins. It can function as ... Protein Lysozyme : Hepatitis B Surface Antigen : >3 mg/ml. 7 mg/ml. ... Antigenic Protein Purification and Depyrogenation Cellufine Sulfate is ideal for depyrogenating virus and other microbial ...
  http://www.amsbio.com/affinity-chromatography.aspx
*  Systems, devices, and methods including catheters having components that are actively controllable between two or more...
C3b-inactivator, C4 binding protein, C4 component, C4a component, C4-binding protein, C5 component, C5a component, C6 component ... complement components, coagulation factors, coagulation proteins, complement components, c-peptide, c-reactive protein, ... basic protein B1, basic protein B2, 0.6 S γ2-globulin, 2 S γ 2-globulin, post γ-globulin, or the like. [0296] Among complement ... myelin basic protein, neuron-specific enolase, potassium, proteins, S-100 protein, small molecules, sodium, β2-microglobulin, ...
  http://www.patentsencyclopedia.com/app/20110152789
*  Systems, devices, and methods including catheters having UV-Energy emitting coatings - Patent application
C3b-inactivator, C4 binding protein, C4 component, C4a component, C4-binding protein, C5 component, C5a component, C6 component ... complement components, coagulation factors, coagulation proteins, complement components, c-peptide, c-reactive protein, ... basic protein B1, basic protein B2, 0.6 S γ2-globulin, 2 S γ 2-globulin, post γ-globulin, or the like. [0296] Among complement ... myelin basic protein, neuron-specific enolase, potassium, proteins, S-100 protein, small molecules, sodium, β2-microglobulin, ...
  http://www.patentsencyclopedia.com/app/20110152751
*  The Importance of C4d in Biopsies of Kidney Transplant Recipients
4. The Complement System and C4d. The complement system consists of several soluble or membrane proteins involved in both ... These convertases cleave the C3 plasma protein into two fragments called C3a and C3b. C3a is an anaphylatoxin, and C3b is a ... and complement receptors (CRs) [53, 54, 72, 73]. One of the ways in which these regulators/inactivators act is by cleaving ... J. E. Locke, C. M. Magro, A. L. Singer et al., "The use of antibody to complement protein C5 for salvage treatment of severe ...
  https://www.hindawi.com/journals/jir/2013/678180/
*  Structure and Modulation of Fc and Complement Receptors | SpringerLink
Complement receptor binding of C3b-coated cells treated with C3b inactivator, beta 1H globulin and trypsin, J. Immunol. 123:523 ... Law, S. K., and Levine, R. P., 1977, Interaction between the third complement protein and cell surface macromolecules, Proc. ... Law, S. K., Fearon, D. T., and Levine, R. P., 1979a, Action of the C3b-inactivator on cellbound C3b, J. Immunol. 122: 759. ... Griffin, F. M., Jr., and Mullinax, P. J., 1981, Augmentation of macrophage complement receptor function in vitro. III. C3b ...
  https://link.springer.com/chapter/10.1007/978-1-4757-4862-8_6
*  Apyrase activity from the crop soluble contents of Rhod | Open-i
Complement Inactivator Proteins/metabolism*. *Complement System Proteins/metabolism*. *Intestines/metabolism*. *Salivary Glands ... C3b, or C4b) on the surface of complement activator molecules linked to microplates. This methodology permitted to identify ... C3b, or C4b) on the surface of complement activator molecules linked to microplates. This methodology permitted to identify ... Bottom Line: Both, saliva and intestinal contents from all triatomines were able to inhibit C3b deposition in the classical and ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2698215_pone.0006047.g002&req=4
*  The complement system
Components of complement system includingC1, C2, C3, C4, C5, C6, C7, C8, C9, C1-INH, C3a-INA, Factors H and I, C3a-INA, C4-BP ... and Factor I, C3a-INA, Protein S (vitronectin). ... Components of complement system includingC1, C2, C3, C4, C5, C6 ... Components of complement system includingC1, C2, C3, C4, C5, C6, C7, C8, C9, C1-INH, C3a-INA, Factors H and I, C3a-INA, C4-BP ... C7, C8, C9, C1-INH, C3a-INA, Factors H and I, C3a-INA, C4-BP and Factor I, C3a-INA, Protein S (vitronectin). ...
  http://periobasics.com/the-complement-system.html
*  Allosteric inhibition of complement function by a staphylococcal immune evasion protein. - PubMed - NCBI
Complement C3b/chemistry. *Complement C3b/metabolism*. *Complement Factor B/metabolism. *Complement Inactivator Proteins/ ... A and B) The cocrystal structures of (A) C3b/fH1-4 (), C3b/CRIg (), and C3c/Compstatin (analog 4W9A, ref. ), and (B) C3b/Bb/ ... Efb-C-induced changes in C3b as revealed by SAXS. (A) Experimental scattering curves for free C3b (black) and C3b/Efb-C (blue) ... A and B) The binding of fB (A) and its fragment Ba (B) to C3b (blue) or C3b/Efb-C (red) was analyzed by SPR as in . (C) ...
  https://www.ncbi.nlm.nih.gov/pubmed/20876141
*  Complement control protein - Wikipedia
Most of the complement control proteins act on the convertases, C3b.Bb and C4b.2a, which are bimolecular complexes formed early ... Complement Inactivator Proteins at the US National Library of Medicine Medical Subject Headings (MeSH). ... "regulators of complement activation (RCA)" or "complement control proteins (CCP)". Complement control proteins work in concert ... Complement control proteins also play a role in malignancy. Complement proteins protect against malignant cells- both by direct ...
  https://en.wikipedia.org/wiki/Complement_control_protein
*  Complement Receptors | Springer for Research & Development
Complement was first described as a heat-labile component in serum with bactericidal activity. It was subsequently found to ... Whaley, K., and Ruddy, S., 1976, Modulation of C3b haemolytic activity by a plasma protein distinct from C3b-inactivator, ... Phorbol Ester Complement Receptor Human Complement Membrane Cofactor Protein Lung Surfactant Protein These keywords were added ... Complement receptor binding of C3b- coated cells treated with C3b inactivator, ß1H globulin and trypsin, J. Immunol. 123: 523- ...
  https://rd.springer.com/chapter/10.1007/978-1-4757-9534-9_9
*  Basic concepts in immunity and inflammation
The complement system involves cleavage reactions, where complement proteins are cleaved into a larger fragment which is ... The resulting C4bC2a complex is a C3 convertase, which cleaves C3 into C3a and C3b. C3b binds to the membrane in association ... C3a inactivator (C3a-INA; Carboxypeptidase B): It inactivates C3a.. Factor H: Its principal function is to regulate the ... The complement system. Term complement means to augment the effect of other components of the immune system. The complement ...
  http://periobasics.com/basic-concepts-in-immunity-and-inflammation.html