*  C3a Complement
C3a is an anaphylatoxin that triggers a response by stimulating inflammatory cells to release histamine, enzymes, cytokines and ... C3a. C3a is a one of the peptides (complement split products) formed by the cleavage of complement component 3. C3a is an ... The ELISA method is sensitive and specific for C3a, using monoclonal anti-C3a antibodies to capture C3a on the 96-well ELISA ... Through these mediators C3a can induce changes in the vascular permeability and local blood flow. It has been shown to be a ...
  https://www.nationaljewish.org/for-professionals/diagnostic-testing/adx/diagnostic-testing/frequently-ordered-tests/c3a
*  C3a (complement) - Wikipedia
C3a is one of the proteins formed by the cleavage of complement component 3; the other is C3b. C3a is a 77 residue ... C3a molecules induce responses through the GPCR C3a receptor. Like other anaphylatoxins, C3a is regulated by cleavage of its ... C3a has a regulatory process and a structure homologous to complement component C5a, with which it shares 36% of its sequence ... C3a formation occurs through activation and cleavage of complement component 3 in a reaction catalyzed by C3-convertase. There ...
  https://en.wikipedia.org/wiki/C3a_(complement)
*  Anti-Complement C3a / C3a des-Arg Antibody (clone 2991) for WB/Western LS-C140007
C3a des-Arg Antibody (clone 2991) for WB/Western LS-C140007 ... Human C3a des-Arg. Specificity:. Human Complement C3a/C3a des- ... Most Popular Complement C3a / C3a des-Arg Antibodies. Anti-Complement C3a / C3a des-Arg Antibody (clone 2991) LS-C140007 ... About Complement C3a / C3a des-Arg. Description:. C3a is one of the proteins formed by the cleavage of complement component 3; ... Mouse Monoclonal [clone 2991] (IgG1) to Human Complement C3a / C3a des-Arg. ...
  https://www.lsbio.com/antibodies/anti-complement-c3a-antibody-c3a-des-arg-antibody-clone-2991-wb-western-ls-c140007/144720
*  Preservation of antimicrobial properties of complement peptide C3a - from invertebrates to humans.
... Pasupuleti, Mukesh LU ; ... Human C3a and C4a (but not C5a) were antimicrobial, in... (More). The human anaphylatoxin peptide C3a, generated during ... article{9d06ba00-5f88-4746-895e-2c5bbf9fe49b, abstract = {The human anaphylatoxin peptide C3a, generated during complement ... The human anaphylatoxin peptide C3a, generated during complement activation, exerts antimicrobial effects. Phylogenetic ...
  https://lup.lub.lu.se/search/publication/164289
*  Complement C3a causes human RPE cells to make basal deposits in vitro | IOVS | ARVO Journals
We recently demonstrated the roles of complement C3a and extracellular matrix (ECM) turnover in an in vitro model for deposit ... Rosario Fernandez-Godino, Donita Garland, Eric A Pierce; Complement C3a causes human RPE cells to make basal deposits in vitro ... Complement C3a causes human RPE cells to make basal deposits in vitro ... Complement C3a causes human RPE cells to make basal deposits in vitro ...
  http://iovs.arvojournals.org/article.aspx?articleid=2563816
*  Complement activation via a C3a receptor pathway alters CD4+ T lymphocytes and mediates lung cancer progression | Cancer...
Complement activation via a C3a receptor pathway alters CD4+ T lymphocytes and mediates lung cancer progression. Jeff W Kwak, ... Complement activation via a C3a receptor pathway alters CD4+ T lymphocytes and mediates lung cancer progression ... Complement activation via a C3a receptor pathway alters CD4+ T lymphocytes and mediates lung cancer progression ... Complement activation via a C3a receptor pathway alters CD4+ T lymphocytes and mediates lung cancer progression ...
  http://cancerres.aacrjournals.org/content/early/2017/11/08/0008-5472.CAN-17-0240.figures-only
*  Application Index: Complement Proteins | China-Mainland | Sigma-Aldrich
Complement Proteins offered by Sigma-alderich online.The complement system is a complex cascade involving proteolytic cleavage ... Complements C3a and C4b are opsonins that bridge phagocytes to microorganisms. Complements C3a and C4a promote phagocyte ... Complement C5a, like C3a is an anaphylatoxin, and is a chemotactic attractant for induction of neutrophilic release of ... Complement factors C3a, C5a and C4 can induce vasodilatation, increased capillary permeability, and expression of leukocyte ...
  http://www.sigmaaldrich.com/china-mainland/zh/life-science/metabolomics/enzyme-explorer/cell-signaling-enzymes/complement-proteins.html
*  Complement C3 antibody | acris-antibodies.com
The complement system is an important part of the humoral response in innate immunity, consisting of three different pathways. ... C3a is a protein of 74 amino acids. C3a itself is very short-lived and in serum is cleaved rapidly into the more stable C3a- ... Rabbit Polyclonal antibody to Complement C3 (complement component 3). Rabbit. IgG. Aff - Purified. Hu, Ms. ICC/IF, P, WB. 0.1 ... measurement of C3a-desArg allows reliable conclusions about the level of complement activation in the test samples. C3a is a ...
  https://www.acris-antibodies.com/target/complement-c3-antibody.htm
*  Lanthanide probes - Wikipedia
"Europium-Labeled Synthetic C3a Protein as a Novel Fluorescent Probe for Human Complement C3a Receptor". Bioconjugate Chemistry ... β2-adrenergic receptor and C3a receptor. The emitted photons from excited lanthanides are detected by highly sensitive devices ...
  https://en.wikipedia.org/wiki/Lanthanide_probes
*  Jia L[au] - PubMed - NCBI
The Complement C3a-C3aR Axis Promotes Development of Thoracic Aortic Dissection via Regulation of MMP2 Expression. ...
  https://www.ncbi.nlm.nih.gov/pubmed?access_num=Jia+L&link_type=AUTHORSEARCH&cmd=search&term=Jia+L%5Bau%5D&dispmax=50
*  Blood and Lymph Unit 3 Flashcards by Kristen Stahl | Brainscape
activate complement cascade. -degrade basement membrane. -C3a and 5a (as anaphylatoxins) release histamine and other mediators ... there the bind C1q and initiate the complement cascade C3a and 5a. -neutrophils are attracted and release a variety of ... IgG binds worm or ova, activates complement, C3a and 5z attract neutrophils. Neutrophils arrive, grab worm with IgG and C3 ... complement and neutrophils cause symptoms-called "allergic" disease but is type 3. -acute attack starts 4-8 hours after ...
  https://www.brainscape.com/flashcards/blood-and-lymph-unit-3-4806757/packs/6999439
*  C3a receptor - Wikipedia
"Characterization of synthetic C3a analog peptides on human eosinophils in comparison to the native complement component C3a". ... is a G protein-coupled receptor protein involved in the complement system. The receptor binds to complement component C3a, ... Complement peptide C5a, C4a, and C3a receptors". Pharmacological Reviews. 65 (1): 500-43. doi:10.1124/pr.111.005223. PMID ... The C3a receptor also known as complement component 3a receptor 1 (C3AR1) ...
  https://en.wikipedia.org/wiki/C3a_receptor
*  Fabry disease: characterisation of the plasma proteome pre- and post-enzyme replacement therapy | Journal of Medical Genetics
Distinct associations of complement C3a and its precursor C3 with atherosclerosis and cardiovascular disease. The CODAM study. ... Complement activation, regulation, and molecular basis for complement-related diseases. Embo J 2015;34:2735-57.doi:10.15252/ ... The activation of any of these three pathways results in the cleavage of C3 to yield C3a and C3b. C3a is an anaphylatoxin that ... In vivo characterisation of complement activation in FD. To assess the in vivo complement status in FD, renal histological ...
  http://jmg.bmj.com/content/54/11/771
*  List of all Brief Reviews Articles | The Journal of Immunology
Is the Complement Activation Product C3a a Proinflammatory Molecule? Re-evaluating the Evidence and the Myth. Liam G. Coulthard ... The Complement System and Antibody-Mediated Transplant Rejection. Erik Stites, Moglie Le Quintrec, and Joshua M. Thurman. J ... Complement in Immune and Inflammatory Disorders: Therapeutic Interventions. Daniel Ricklin and John D. Lambris. J Immunol 2013 ... Complement-Dependent Transport of Antigen into B Cell Follicles. Santiago F. Gonzalez, Veronika Lukacs-Kornek, Michael P. ...
  http://www.jimmunol.org/briefreviews
*  Thomas Martin, MD | Boston Children's Hospital
... are critical for respiratory syncytial virus-associated airway hyperreponsiveness through regulation by complement C3a and ...
  http://www.childrenshospital.org/directory/physicians/m/thomas-martin
*  Atypical haemolytic uraemic syndrome and mutations in complement regulator genes | SpringerLink
Schraufstatter IU, Trieu K, Sikora L et al (2002) Complement c3a and c5a induce different signal transduction cascades in ... Vyse TJ, Spath PJ, Davies KA et al (1994) Hereditary complement factor I deficiency. Qjm 87(7):385-401PubMedGoogle Scholar ... Weis JH, Morton CC, Bruns GA et al (1987) A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr ... Riley-Vargas RC, Gill DB, Kemper C et al (2004) CD46: expanding beyond complement regulation. Trends Immunol 25(9):496-503 ...
  https://link.springer.com/article/10.1007%2Fs00281-005-0003-2
*  PHB - Prohibitin - Meleagris gallopavo (Wild turkey) - PHB gene & protein
complement component C3a binding Source: Ensembl. *complement component C3b binding Source: Ensembl ...
  http://www.uniprot.org/uniprot/G1MU38
*  Wound Healing and Repair: Overview, Types of Wound Healing, Categories of Wound Healing
Other chemotactic agents are released, including FGF, TGF-β and TGF-α, PDGF, and plasma-activated complements C3a and C5a ( ...
  https://emedicine.medscape.com/article/1298129-overview
*  Microarray Analysis of Differential Gene Expression Profile in Peripheral Blood Cells of Patients with Human Essential...
Complement component C3a receptor activity. 1. 7.16E-4. 4.4E-4. ... C3a anaphylatoxin receptor activity. 1. 7.16E-4. 4.4E-4. ... complement component 3a receptor 1. -1.678515094. 0.661637838. 107.40645. 201137_s_at. HLA-DPB1. major histocompatibility ... Complement factor D (adipsin). -1.817904316. 0.378262489. 107.40645. * The student's t-statistic value; #The lowest False ... complement component 4 binding protein, alpha. 2.720863469. 2.035574937. 107.3708967. 204838_s_at. MLH3. mutL homolog 3 (E. ...
  http://www.medsci.org/v08p0168.htm
*  Calcium Signaling in Microglial Cells | SpringerLink
Möller T, Nolte C, Burger R, Verkhratsky A, Kettenmann H (1997a). Mechanisms of C5a and C3a complement fragment-induced [Ca2+]i ... Expression of receptors for complement anaphylatoxins C3a and C5a following permanent focal cerebral ischemia in the mouse. Exp ... Morgan BP (2000). The complement system: an overview. Methods Mol Biol 150:1-13.PubMedGoogle Scholar ... Morgan BP, Gasque P (1996). Expression of complement in the brain: role in health and disease. Immunology Today 17:461-466. ...
  https://link.springer.com/chapter/10.1007/978-1-4757-4139-1_4
*  c3a - PCR Primer Pair - SYBR | PrimePCR | Bio-Rad
c3a. Gene Name:. Complement component c3a. Aliases:. Not Available. RefSeq:. NM_131242. ... PrimePCR™ SYBR® Green Assay: c3a, Zebrafish. print Real-time PCR primer assay designed for SYBR® Green gene expression analysis ... Home , Life Science Research , Products , PCR Amplification , PrimePCR™ PCR Primers, Assays, and Arrays , Gene: c3a, Zebrafish ... PrimePCR™ PreAmp for SYBR® Green Assay: c3a, Zebrafish Reaction: 400 reactions Gene-specific PCR primers for the unbiased ...
  http://www.bio-rad.com/en-us/prime-pcr-assays/assay/qdrecid0018882-primepcr-sybr-green-assay-c3a-zebrafish
*  C3a | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY
C3a ligand page. Quantitative data and detailed annnotation of the targets of licensed and experimental drugs. ... complement component 3 Mouse prepro-C3 acylation stimulating protein, complement factor 3, Plp ...
  http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=3641
*  Collective cell migration - Wikipedia
"Complement fragment C3a controls mutual cell attraction during collective cell migration". Developmental Cell. 21 (6): 1026-37 ... C3a in neural crest cells), that stimulates other cells in the group that have the receptors to that chemo-attractant. Cells ...
  https://en.wikipedia.org/wiki/Collective_cell_migration