*  C3 Nephritic Factor | Diagnostic Testing | Clinical Laboratory
Complement Lab. Synonyms. Complement (C3 Nephritic Factor);2-D Immunoelectrophoresis (C3 Nephritic Factor) ... This is not a direct measurement of antibody quality, but only a qualitative (indirect) measure of its activity in causing C3 ...
  https://www.nationaljewish.org/for-professionals/diagnostic-testing/adx/tests/c3-nephritic-factor
*  PED Flashcards by Dimitrios Drekolias | Brainscape
A/w accelerated complement activation and C3 nephritic factor ==> Hypothesized to cause lysis of adipose tissue. ...
  https://www.brainscape.com/flashcards/ped-6562480/packs/10385697
*  List of MeSH codes (D12.776) - Wikipedia
... complement c3 nephritic factor MeSH D12.776.377.715.548.114.323.390 - immunoconglutinins MeSH D12.776.377.715.548.114.323.480 ... complement factor h MeSH D12.776.377.715.182.338 - hemopexin MeSH D12.776.377.715.182.580 - plasminogen MeSH D12.776.377.715. ... vascular endothelial growth factor a MeSH D12.776.467.100.800.300 - vascular endothelial growth factor b MeSH D12.776.467.100. ... fibroblast growth factor 4 MeSH D12.776.624.664.700.112 - fibroblast growth factor 6 MeSH D12.776.624.664.700.114 - fms-like ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776)
*  Barraquer-Simons syndrome - Wikipedia
... low C3 serum complement levels, and the presence of a C3 nephritic factor. C3 nephritic factor is a serum immunoglobulin G that ... C3 nephritic factor induces the lysis of adipocytes that secrete adipsin, a product identical to complement factor D. The ... Around 83% of APL patients had low complement 3 (C3) levels and the presence of polyclonal immunoglobulin C3 nephritic factor. ... due to complement activation and consumption of C3). Low C3 levels may impair complement-mediated phagocytosis and bacterial ...
  https://en.wikipedia.org/wiki/Barraquer%E2%80%93Simons_syndrome
*  List of MeSH codes (D12.776.124) - Wikipedia
... complement c1 inhibitor protein MeSH D12.776.124.486.274.920.287 -- complement c3 nephritic factor MeSH D12.776.124.486.274.920 ... complement factor h MeSH D12.776.124.486.274.920.325.210 -- complement factor i MeSH D12.776.124.486.274.920.662 -- complement ... complement factor d MeSH D12.776.124.486.274.900 -- complement factor b MeSH D12.776.124.486.274.920 -- complement inactivator ... complement c3 nephritic factor MeSH D12.776.124.486.485.114.323.390 -- immunoconglutinins MeSH D12.776.124.486.485.114.323.480 ...
  https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D12.776.124)
*  Progressive Lipodystrophy
... low C3 serum complement levels, and the presence of a C3 nephritic factor. C3 nephritic factor is a serum immunoglobulin G that ... C3 nephritic factor induces the lysis of adipocytes that secrete adipsin, a product identical to complement factor D. The ... Hypocomplementemia is characterized by a low C3 complement level, a normal C4 level, and the presence of C3 nephritic factor. ... Adipocytes synthesize factor D, the limiting component of the alternative complement pathway, which cleaves C3-bound factor B ...
  http://misc.medscape.com/pi/iphone/medscapeapp/html/A1082489-business.html
*  Complement, not Compliment | PascaleLane's Stream of Thought
... that occurs with activation of the complement system of immunity. The Complement System The complement system of proteins ... and complements: C3, C4, and C3 nephritic factor. The latter, an antibody to the activated form of C3 that can activate C5, is ... After a couple of steps it activates C3. Ultimately C5 and other complements come together, resulting in a membrane attack ... If C4 is low, then the classical pathway has been stimulated; C3 may be suppressed as well. If C4 remains normal with a low C3 ...
  https://pascalelane.wordpress.com/2011/12/30/complement-not-compliment/
*  Lipodystrophy, including Lipoatrophy
... and autoimmune disorders.Presence of C3 nephritic factor. C3 nephritic factor casues activation of the alternative complement ... This is associated with increased C3 nephritic factor levels, which is responsible for decreased C3 levels. ... A lack of knowledge regarding specific etiopathogenic factors, as well as the opportunism of some professionals and the media, ... The FDA has approved tesamorelin (synthetic analogue of growth hormone-relasing factor) acetate injection as the first and only ...
  http://www.psychiatryadvisor.com/dermatology/lipodystrophy-including-lipoatrophy/article/589225/
*  Pediatric Nephritis: Practice Essentials, Etiology, Epidemiology
C3 nephritic factor associated with C3 glomerulopathy in children. Pediatr Nephrol. 2014 Jan. 29 (1):85-94. [Medline]. ... Defining the complement biomarker profile of C3 glomerulopathy. Clin J Am Soc Nephrol. 2014 Nov 7. 9 (11):1876-82. [Medline]. ... Nephritic syndrome may occur in people of all races. The race of the child is not generally helpful in determining the primary ... C3 glomerulopathy: clinicopathologic features and predictors of outcome. Clin J Am Soc Nephrol. 2014 Jan. 9 (1):46-53. [Medline ...
  https://emedicine.medscape.com/article/982811-overview
*  Homologous restriction factor | definition of homologous restriction factor by Medical dictionary
... homologous restriction factor explanation free. What is homologous restriction factor? Meaning of homologous restriction factor ... Looking for online definition of homologous restriction factor in the Medical Dictionary? ... Christmas factor coagulation f. IX.. C3 nephritic factor (C3 NeF) an autoantibody that stabilizes the alternative complement ... Rheumatoid factor, Rho factor, Risk factor, S factor, Safety factor, Satiation factor, Scatter factor, Serum spreading factor, ...
  http://medical-dictionary.thefreedictionary.com/homologous+restriction+factor
*  Glomerulonephritis - Wikipedia
The C3 Nephritic Factor autoantibody stabilizes C3-convertase, which may lead to an excessive activation of complement. Rapidly ... The nephritic syndrome is characterised by blood in the urine (especially Red blood cell casts with dysmorphic red blood cells ... These forms usually present with a triad of blood in the urine, decreased urine production, and hypertension, the nephritic ... Type 2 MPGN, also known as Dense Deposit Disease, is characterised by an excessive activation of the complement system. ...
  https://en.wikipedia.org/wiki/Glomerulonephritis
*  Eosinophil colony-stimulating factor | definition of eosinophil colony-stimulating factor by Medical dictionary
What is eosinophil colony-stimulating factor? Meaning of eosinophil colony-stimulating factor medical term. What does ... Looking for online definition of eosinophil colony-stimulating factor in the Medical Dictionary? eosinophil colony-stimulating ... Christmas factor coagulation f. IX.. C3 nephritic factor (C3 NeF) an autoantibody that stabilizes the alternative complement ... Rheumatoid factor, Rho factor, Risk factor, S factor, Safety factor, Satiation factor, Scatter factor, Serum spreading factor, ...
  https://medical-dictionary.thefreedictionary.com/eosinophil+colony-stimulating+factor
*  Factor VIII activity | definition of factor VIII activity by Medical dictionary
What is factor VIII activity? Meaning of factor VIII activity medical term. What does factor VIII activity mean? ... Looking for online definition of factor VIII activity in the Medical Dictionary? factor VIII activity explanation free. ... Christmas factor coagulation f. IX.. C3 nephritic factor (C3 NeF) an autoantibody that stabilizes the alternative complement ... Rheumatoid factor, Rho factor, Risk factor, S factor, Safety factor, Satiation factor, Scatter factor, Serum spreading factor, ...
  http://medical-dictionary.thefreedictionary.com/factor+VIII+activity
*  Glomerulonephritis - Wikipedia
The C3 Nephritic Factor autoantibody stabilizes C3-convertase, which may lead to an excessive activation of complement.[4]:553 ... Main article: Nephritic syndrome. The nephritic syndrome is characterised by blood in the urine (especially Red blood cell ... Nephritic syndromeEdit. Podocytes, cells which line the glomerulus, are negatively charged and have small gaps, preventing the ... These forms present with the nephritic syndrome, hypocomplementemia, and have a poor prognosis. Two primary subtypes exist:[4]: ...
  https://en.m.wikipedia.org/wiki/Glomerulonephritis
*  Pathology Flashcards by John DeWaard | Brainscape
Due to activation of alternate complement pathway. *Most patients have C3 nephritic factor in the serum ... Linear IgG and C3 deposits in GBM. *Antibodies may cross-react w/ pulmonary alveolar basement membranes to produce pulmonary ... Tissue factor activates the coagulation pathway (adding to size of thrombus). *Thrombus evolves to partly or completely occlude ... Present w/ nephritic syndrome. *Course is somewhat variable, depending upon type, but renal involvement is rapidly progressive ...
  https://www.brainscape.com/flashcards/pathology-6828613/packs/10860859
*  B cell stimulatory factor II | definition of B cell stimulatory factor II by Medical dictionary
What is B cell stimulatory factor II? Meaning of B cell stimulatory factor II medical term. What does B cell stimulatory factor ... Looking for online definition of B cell stimulatory factor II in the Medical Dictionary? B cell stimulatory factor II ... Christmas factor coagulation f. IX.. C3 nephritic factor (C3 NeF) an autoantibody that stabilizes the alternative complement ... Rheumatoid factor, Rho factor, Risk factor, S factor, Safety factor, Satiation factor, Scatter factor, Serum spreading factor, ...
  http://medical-dictionary.thefreedictionary.com/B+cell+stimulatory+factor+II
*  Renal Fellow Network: Idiopathic MPGN and its subtypes. Or: I'm going to need the whole bottle to get through this
It is associated with dysregulation of the alternative complement pathway through C3NeF (C3 nephritic factor), which stabilizes ... resulting in perpetual breakdown of C3 and continuously activated alternative complement pathway. Factor H deficiency or ... He had a slow reacting C3NeF, low C3, normal C4, low terminal complement levels, and by biopsy had paramesangial and ... It is associated with a slow acting nephritic factor of the terminal pathway(NeFt), which stabilizes a properdin dependent C5 ...
  http://renalfellow.blogspot.com/2011/05/idiopathic-mpgn-and-its-subtypes-or-im.html
*  Renal Fellow Network: May 2011
It is associated with dysregulation of the alternative complement pathway through C3NeF (C3 nephritic factor), which stabilizes ... resulting in perpetual breakdown of C3 and continuously activated alternative complement pathway. Factor H deficiency or ... It is important to add complements and cryo to your workup.. *MPGN: (low C3 and C4) Renal manifestations range from hematuria ... He had a slow reacting C3NeF, low C3, normal C4, low terminal complement levels, and by biopsy had paramesangial and ...
  http://renalfellow.blogspot.com/2011/05/
*  Complement C3-C5 Convertases - C3 Convertase Summary Report | CureHunter
Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B, or cleave COMPLEMENT C5 into COMPLEMENT C5A ... These include the different forms of C3/C5 convertases in the classical and the alternative pathways of COMPLEMENT ACTIVATION. ... Anti-C3 NAb preparations exhibited nephritic factor activity that was up to 60 times stronger than that of total IgG from a ... Complement 5 Convertase; Complement C3 Convertases; Complement C5 Convertases; Activator, C3; C3 Convertases, Complement; C3-C5 ...
  http://www.curehunter.com/public/keywordSummaryD050577-Complement-C3-C5-Convertases-C3-Convertase.do
*  Antibodies - MeSH - NCBI
Complement C3 Nephritic FactorImmunoconglutininsImmunoglobulins, Thyroid-Stimulating +Rheumatoid FactorImmune Sera ... Complement C3 Nephritic FactorImmunoconglutininsImmunoglobulins, Thyroid-Stimulating +Rheumatoid FactorImmune Sera ... Complement C3 Nephritic FactorImmunoconglutininsImmunoglobulins, Thyroid-Stimulating +Rheumatoid FactorImmune Sera ... Immunologic Factors. All MeSH CategoriesChemicals and Drugs CategoryAmino Acids, Peptides, and ProteinsProteinsBlood Proteins ...
  https://www.ncbi.nlm.nih.gov/mesh?Db=mesh&Cmd=DetailsSearch&Term=%22Antibodies%22%5BMeSH+Terms%5D
*  Barraquer-Simons syndrome: a rare form of acquired lipodystrophy | BMC Research Notes | Full Text
The lack of C3 allows for a clear distinction between this syndrome and other forms of lipodystrophy. The C3-nephritic factor ... Complement mediated adipocyte lysis by nephritic factor sera. J Exp Med. 1993;177:1827-31.View ArticlePubMedGoogle Scholar. ... C3), and the presence of the C3-nephritic factor [14, 15]. The authors describe the clinical case of a female patient with ... Patients usually have decreased serum complement-component 3 levels, associated with complement activation by the alternative ...
  https://0-bmcresnotes-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s13104-016-1975-9
*  M. Amin Arnaout - Wikipedia
He was the first to show that C3 nephritic factor is an autoantibody that activates the alternative complement pathway, a ... finding that suggested the potential of B cell or complement C5 depletion as adjunct therapies in certain forms of kidney ...
  https://en.wikipedia.org/wiki/M._Amin_Arnaout
*  Complement factor b | definition of Complement factor b by Medical dictionary
What is Complement factor b? Meaning of Complement factor b medical term. What does Complement factor b mean? ... Looking for online definition of Complement factor b in the Medical Dictionary? Complement factor b explanation free. ... clotting f's coagulation factors.. C3 nephritic factor (C3 NeF) an autoantibody that stabilizes the alternative complement ... stable factor factor VII, one of the coagulation factors.. Stuart factor (Stuart-Prower factor) factor X, one of the ...
  http://medical-dictionary.thefreedictionary.com/Complement+factor+b
*  Membranoproliferative GN
C3 nephritic factor, an autoantibody to the alternative pathway C3 convertase C3bBb, is seen in 60-70% of those with type II ... Genetic predisposition to MPGN is linked to mutations in factor H or other complement proteins such as C3 that lead to abnormal ... Genetic mutations in factor H or other proteins in the alternative pathway of complement can result in a predisposition to the ... Type I MPGN is associated with a low C3 and reduced levels of terminal components of the complement cascade, C6, C7, and C9. ...
  http://www.neurologyadvisor.com/pediatrics/membranoproliferative-gn/article/622095/
*  C4 Nephritic Factor | Molecular Otolaryngology and Renal Research Laboratories
C3 Nephritic Factor/C5 Nephritic Factor/Nef Activity. *C4 Nephritic Factor. *Complement C3 Plasma Level ... Tanuma, Y, et al.: C3 nephritic factor and C4 nephritic factor in the serum of two patients with hypocomplementaemic ... C4 Nephritic Factors Dense Deposit Disease and C3 Glomerulonephritis Testing is appropriate for patients with C3 glomerulopathy ... Halbwachs L, et al.: Nephritic factor of the classical pathway of complement: immunoglobulin G autoantibody directed against ...
  https://morl.lab.uiowa.edu/clinical-diagnostics/complement-assays/tests-included/c4-nephritic-factor