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*  Membrane Docking Pathway Bioinformatics: Novus Biologicals
Complement Component C2b Antibody (269716). MAB1936. Mouse Monoclonal Species Human. Applications WB, IP ... The Membrane Docking Pathway complements our catalog of research reagents including antibodies and ELISA kits against SNARE, ...
  https://www.novusbio.com/pathways/membrane-docking
*  C2 Gene - GeneCards | CO2 Protein | CO2 Antibody
Complement C2, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene ... complement component 2,110kDa,activated by C1r to form C2a and C2b,combining with C4A and C4B to form C3/C5 convertase, ... Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or ... Complement component 2 (A2BE06_HUMAN). *cDNA FLJ38939 fis, clone NT2NE2015747, highly similar to COMPLEMENT C2 (EC 3.4.21.43) ( ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=C2
*  Human Gene C2 (uc011hbu.2) Description and Page Index
DESCRIPTION: SubName: Full=Complement C2b fragment; SubName: Full=cDNA FLJ54376, highly similar to Complement C2 (EC 3.4.21.43 ... h_compPathway - Complement Pathway. h_classicPathway - Classical Complement Pathway. h_lectinPathway - Lectin Induced ... Genetic variation in complement component 2 of the classical complement pathway is associated with increased mortality and ... hsa04610 - Complement and coagulation cascades. hsa05322 - Systemic lupus erythematosus. BioCarta from NCI Cancer Genome ...
  http://rohsdb.cmb.usc.edu/GBshape/cgi-bin/hgGene?hgg_gene=uc011hbu.2&hgg_prot=B4DQI1&hgg_chrom=chr6_mann_hap4&hgg_start=3244195&hgg_end=3256269&hgg_type=knownGene&db=hg19&hgsid=1289098_rEYyzmWZ9Xw4hhMOGbGzlYRwArae
*  Complement component 2 - Wikipedia
C2 complement component 2". Krishnan V, Xu Y, Macon K, Volanakis JE, Narayana SV (2009). "The structure of C2b, a fragment of ... Complement C2 is a protein that in humans is encoded by the C2 gene. The protein encoded by this gene is part of the classical ... C2b is the larger, enzymatically active fragment which is incorporated into the C3 convertase in this pathway, C4b2b. C2a is ... It is thought that cleavage of C2 by C1s, while bound to C4b, results in a conformational rotation of C2b whereas the released ...
  https://en.wikipedia.org/wiki/Complement_component_2
*  EC 3.4.21.43
... complement C3 convertase. Comments: A complex of complement fragments C4b, C2a and C2b. C2a contains the active site, C2b the ... C2a and C2b are formed by cleavage of proenzyme C2 by complement subcomponent C. . Cleavage of C5 requires complement fragment ... Ser bond in complement component C3 α-chain to form C3a and C3b, and Arg. bond in complement component C5 α-chain to form C5a ... Complement component C2a is in peptidase family S1 (trypsin family). Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, ...
  http://www.sbcs.qmul.ac.uk/iubmb/enzyme/EC3/4/21/43.html
*  Complement C4b Antibody (25.3F4) [DyLight 755] (NBP2-31554IR): Novus Biologicals
Mouse Monoclonal Anti-Complement C4b Antibody (25.3F4) [DyLight 755]. Validated: WB, ELISA. Tested Reactivity: Human. 100% ... Home » Complement C4b » Complement C4b Antibodies » Complement C4b Antibody (25.3F4) [DyLight 755] ... Blogs on Complement C4b. There are no specific blogs for Complement C4b, but you can read our latest blog posts. ... Reviews for Complement C4b Antibody (NBP2-31554IR) (0) There are no reviews for Complement C4b Antibody (NBP2-31554IR). By ...
  https://www.novusbio.com/products/complement-c4b-antibody-253f4_nbp2-31554ir
*  Complement Factor MASP3/MASP1 Overexpression Lysate (Native) (NBP2-05611): Novus Biologicals
Complement Factor MASP3/MASP1 Overexpression Lysate (Native). Tested Reactivity: Hu. Validated: WB. Backed by our 100% ... Additional Complement Factor MASP3/MASP1 Products. Complement Factor MASP3/MASP1 NBP2-05611 * Complement Factor MASP3/MASP1 ... Blogs on Complement Factor MASP3/MASP1. There are no specific blogs for Complement Factor MASP3/MASP1, but you can read our ... Reviews for Complement Factor MASP3/MASP1 Lysate (NBP2-05611) (0) There are no reviews for Complement Factor MASP3/MASP1 Lysate ...
  https://www.novusbio.com/products/complement-factor-masp3-masp1-lysate_nbp2-05611
*  Complement Factor H Antibody (C18/3) [Alexa Fluor® 700] (NBP2-23542AF700): Novus Biologicals
Mouse Monoclonal Anti-Complement Factor H Antibody (C18/3) [Alexa Fluor® 700]. Validated: WB, ELISA. Tested Reactivity: Human. ... Home » Complement Factor H » Complement Factor H Antibodies » Complement Factor H Antibody (C18/3) [Alexa Fluor® 700] ... Blogs on Complement Factor H. There are no specific blogs for Complement Factor H, but you can read our latest blog posts. ... PTMs for Complement Factor H Antibody (NBP2-23542AF700). Learn more about PTMs related to Complement Factor H Antibody (NBP2- ...
  https://www.novusbio.com/products/complement-factor-h-antibody-c18-3_nbp2-23542af700
*  Complement C3a Antibody (K13/16-5.7) [Alexa Fluor® 405] (NBP1-05122AF405): Novus Biologicals
Mouse Monoclonal Anti-Complement C3a Antibody (K13/16-5.7) [Alexa Fluor® 405]. Validated: WB, ELISA, ICC/IF, IHC, IHC-P. Tested ... Home » Complement C3a » Complement C3a Antibodies » Complement C3a Antibody (K13/16-5.7) [Alexa Fluor® 405] ... Blogs on Complement C3a. There are no specific blogs for Complement C3a, but you can read our latest blog posts. ... PTMs for Complement C3a Antibody (NBP1-05122AF405). Learn more about PTMs related to Complement C3a Antibody (NBP1-05122AF405). ...
  https://www.novusbio.com/products/complement-c3a-antibody-k13-16-57_nbp1-05122af405
*  Complement in Immune and Inflammatory Disorders: Pathophysiological Mechanisms | The Journal of Immunology
The enzymatic fragment of C2 is referred to as C2b in this review; the same fragment is sometimes designated as C2a in ... Complement beyond microbial defense. The past decade revealed a new perception of complement that reaches beyond the ... Complement can also be therapeutically engaged for the killing of tumor cells via complement-dependent cytotoxicity; for ... Beneficial effects of complement inhibition with soluble complement receptor 1 (TP10) during cardiac surgery: is there a gender ...
  http://www.jimmunol.org/content/190/8/3831
*  Anti-C2 antibody [5C3] (ab17451) | Abcam
C2b and C2a. C2a, a serine protease, then combines with complement factor 4b to generate the C3 or C5 convertase. ... Defects in C2 are the cause of complement component 2 deficiency (C2D) [MIM:217000]. A deficiency of the complement classical ... Human complement component C2: production and characterization of polyclonal and monoclonal antibodies against C2.. Mol Immunol ... No se ha testado si el anticuerpo reacciona con el fragmento C2b en su forma purificada. Espero haberte ayudado. Para cualquier ...
  https://www.abcam.com/c2-antibody-5c3-ab17451.html
*  C5-convertase - Wikipedia
The classical pathway C5 convertase is composed of the larger fragments of complement proteins, C4b, C2b produced by cleavage ... The complement component C5 can be also activated by fluid phase C5 convertase. C5 is activated by CVFBb in the presence of ... In these respects, the mode of action of C5 is completely analogous to that of the other components of complement. The C5 step ... The binding of C5 is influenced by C6 and C7, components which are thought to act subsequent to it in the complement sequence. ...
  https://en.wikipedia.org/wiki/C5-convertase
*  C2 MaxPab mouse polyclonal antibody (B01) - (H00000717-B01) - Products - Abnova
Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or ... Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. ...
  https://www.abnova.com/products/products_detail.asp?Catalog_id=H00000717-B01
*  C2 monoclonal antibody (M17), clone 5C3 - (H00000717-M17) - Products - Abnova
Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or ... Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. ...
  http://www.abnova.com/products/products_detail.asp?Catalog_id=H00000717-M17
*  Frontiers | The Complement System: A Prey of Trypanosoma cruzi | Microbiology
The complement consists of at least 35 or more plasma proteins and cell surface receptors/regulators, which can be activated by ... The complement consists of at least 35 or more plasma proteins and cell surface receptors/regulators, which can be activated by ... In this context, the complement, as one of the first line of host defense against infection was shown to play an important role ... Nevertheless, the parasite uses a sequence of events in order to escape from complement-mediated lysis. In fact, several T. ...
  https://www.frontiersin.org/articles/10.3389/fmicb.2017.00607/full
*  Reactome | Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane]
Complement cascade (Homo sapiens) * Initial triggering of complement (Homo sapiens) * Conversion of C2 into C2a and C2b (Homo ... Lectin pathway of complement activation (Homo sapiens) * Activation of MASPs (Homo sapiens) * MBL2,FCN:activated MASPs: ...
  https://reactome.org/content/detail/R-HSA-2855106
*  Reactome | Ig lambda chain V-II region TOG [extracellular region]
Complement cascade (Homo sapiens) * Initial triggering of complement (Homo sapiens) * Conversion of C2 into C2a and C2b (Homo ... Classical antibody-mediated complement activation (Homo sapiens) * Activation of C1r (Homo sapiens) * Antigen:IgG:C1Q:2x ... Regulation of Complement cascade (Homo sapiens) * Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates ...
  https://reactome.org/content/detail/R-HSA-983664
*  Immuno Five: Complement Flashcards - Cram.com
Complement at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com makes it easy to get the grade you want! ... C2b a weak kinin, and so can increase vascular permeability, it is a proteolytic fragment of C2 ... term which refers to the spontaneous production of C3b which will activate AP of complement ... ":"Immuno Five: Complement","payreferer_url":"\/flashcards\/copy\/immuno-five-complement-503728","isGuest":true,"ga_id":"UA- ...
  http://www.cram.com/flashcards/immuno-five-complement-503728
*  Complement system - Wikipedia
... and C2b. C4b and C2b (historically, the larger fragment of C2 was called C2a but is now referred to as C2b) bind to form the ... Polymorphisms of complement component 3, complement factor B, and complement factor I, as well as deletion of complement factor ... Here, for consistency, we shall call all large fragments of complement b, so the larger fragment of C2 will be designated C2b. ... Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway ...
  https://en.wikipedia.org/wiki/Complement_system
*  Reactome | C1S N-terminal fragment [extracellular region]
Complement cascade (Homo sapiens) * Initial triggering of complement (Homo sapiens) * Conversion of C2 into C2a and C2b (Homo ... Classical antibody-mediated complement activation (Homo sapiens) * Activation of C1s (Homo sapiens) * Antigen:IgG:C1Q:2x ... Regulation of Complement cascade (Homo sapiens) * Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates ...
  https://reactome.org/content/detail/R-HSA-173607
*  Reactome | A0A287B484 [extracellular region]
Complement cascade (Sus scrofa) * Initial triggering of complement (Sus scrofa) * Conversion of C2 into C2a and C2b (Sus scrofa ... Classical antibody-mediated complement activation (Sus scrofa) * Activation of C1r (Sus scrofa) * Antigen:IgG:C1Q:2x Activated ... Regulation of Complement cascade (Sus scrofa) * Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates ( ...
  https://reactome.org/content/detail/R-SSC-983550-19
*  Reactome | Ca2+ [extracellular region]
Complement cascade (Bos taurus) * Initial triggering of complement (Bos taurus) * Conversion of C2 into C2a and C2b (Bos taurus ... Lectin pathway of complement activation (Bos taurus) * Activation of MASPs (Bos taurus) * MBL2,FCN:MASPs:carbohydrate patterns ... Classical antibody-mediated complement activation (Bos taurus) * Activation of C1r (Bos taurus) * C-reactive protein pentamer: ... Regulation of Complement cascade (Bos taurus) * Thrombin, ELANE cleave C5 (Bos taurus) * Activated thrombin, (ELANE) [ ...
  https://reactome.org/content/detail/R-ALL-74112
*  Evolving Immunity
The origin and evolution of the complement system. *The evolution of complement begins with an ancestor to protease inhibitor a ... C2 can then attach to C4b, and is then cleaved by C1 into C2a and C2b. C2b and C4b then form the second serine protease in the ... Model for the evolution of the complement system Any model for the origin of the complement system must begin with the ... The complement system - Behe's largest error in chapter 6 is choosing the complement system as an example of how evolution ...
  http://www.talkdesign.org/faqs/Evolving_Immunity1.2.html
*  Evolving Immunity
... complement protein homologous to complement C3 of the mammalian complement system." Journal of Immunology 133(6): 3242-3249. ... C2 can then attach to C4b, and is then cleaved by C1 into C2a and C2b. C2b and C4b then form the second serine protease in the ... The origin and evolution of the complement system. *The evolution of complement begins with an ancestor to protease inhibitor a ... Model for the evolution of the complement system Any model for the origin of the complement system must begin with the ...
  http://www.talkdesign.org/faqs/Evolving_Immunity.html
*  Complement
C2b. Unknown.. C3. C3a. Mediates inflammation; anaphylatoxin.. C3b. Binds C5 for cleavage by C2a.. Binds cell surfaces for ... Complement. COMPONENTS AND FUNCTIONS OF THE COMPLEMENT SYSTEM The complement system found in the blood of mammals is composed ... ACTIVATION OF THE COMPLEMENT CASCADE Classical Pathway The classical pathway starts with C1; C1 binds to immunoglobulin Fc ( ... Most of the complement components are numbered (e.g. C1, C2, C3, etc.) but some are simply refered to as 'Factors'. Some of the ...
  http://medmicro.atwebpages.com/cment.htm