*  Undiagnosed metabolic syndrome and other adverse effects among clozapine users of Xhosa descent
FAASEN, N; NIEHAUS, D J H; KOEN, L e JORDAAN, E. Undiagnosed metabolic syndrome and other adverse effects among clozapine users ... BACKGROUND: Clozapine use is known to be associated with significant side-effects, including prolongation of the QT-interval, ... However, few data exist on the prevalence of clozapine side-effects in patients of Xhosa descent. OBJECTIVE: To gather data ... There was an association between the duration of clozapine treatment and QT-interval (with Bazett's correction. CONCLUSION: The ...
  http://www.scielo.org.za/scielo.php?script=sci_abstract&pid=S2078-67862014000200005&lng=pt&nrm=iso
*  5786-21-0|Clozapine|API
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  http://jpet.aspetjournals.org/content/283/2/636
*  Aripiprazole versus haloperidol in combination with clozapine for treatment-resistant schizophrenia in routine clinical care: a...
Patients continued to take clozapine and were randomly assigned to receive daily augmentation with aripiprazole or haloperidol ... treatment with clozapine plus haloperidol in patients with schizophrenia who do not have an optimal response to clozapine. ... These results suggest that augmentation of clozapine with aripiprazole offers no benefit with regard to treatment withdrawal ... This multisite study was conducted to compare the efficacy and tolerability of combination treatment with clozapine plus ...
  https://www.neuroscience.ox.ac.uk/publications/425993
*  Augmenting clozapine with sertindole - a double blinded randomized placebo study - AdisInsight
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  http://adisinsight.springer.com/trials/700019349?error=cookies_not_supported&code=ed6dd7b7-9fd2-4dbd-9e1f-b3ea1b78036c
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*  Clozapine | Atypical antipsychotic | CAS [5786-21-0] | Axon 1146 | Axon Ligand™ with |99% purity available from stock from...
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*  Amisulpride Augmentation in Clozapine-unresponsive Schizophrenia - Full Text View - ClinicalTrials.gov
Any direct pharmacokinetic effect on clozapine levels will be assessed by pre- and post-augmentation plasma levels of clozapine ... Indication for current treatment with clozapine was intolerance/movement disorder. *A previous trial of clozapine augmentation ... as mentioned in the SPCs for clozapine and amisulpride. Medication adherence will be assessed by 'pill count' and clozapine/ ... Amisulpride Augmentation in Clozapine-unresponsive Schizophrenia (AMICUS). The safety and scientific validity of this study is ...
  https://clinicaltrials.gov/show/NCT01246232
*  Evidence for the Role of Metabotropic Glutamate (mGlu)2 Not mGlu3 Receptors in the Preclinical Antipsychotic Pharmacology of...
... we investigated the ability of clozapine and risperidone to reverse PCP-evoked hyperlocomotion. Clozapine and risperidone were ... Clozapine and risperidone attenuated PCP-evoked reductions in time at rest approximately 5-fold [Fig. 4c; F(3,28) = 33.26, p , ... Effect of clozapine (10 mg/kg) or risperidone (1 mg/kg) on PCP (7.5 mg/kg)-evoked ambulations (a), distance traveled (b) and ... Both clozapine and risperidone significantly reduced PCP-evoked ambulations [Fig. 4a; F(3,28) = 66.74, p , 0.001] and distance ...
  http://jpet.aspetjournals.org/content/326/1/209.long
*  Clozapine-Induced Hypersensitivity Myocarditis* - Redorbit
Clozapine-related myocarditis or acute viral myocarditis following a throat infection then was suspected, clozapine therapy was ... Clozapine is the "gold standard" treatment for schizophrenia patients who are resistant to neuroleptics. Its use, limited by ... In our patient, clozapine therapy was clealy indicated, and had a rapid and impressiye efficacy, therefore drug withdrawal ... Clozapine withdrawal and targeted 8-day, low-dose corticosteroid therapy resolved the symptoms and restored cardiac function. ( ...
  http://www.redorbit.com/news/health/106580/clozapineinduced_hypersensitivity_myocarditis/
*  clozapine | Cigna
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*  Clozapine: Efficacy and Safety
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  http://www.mentalhealth.com/mag1/scz/sb-cloz.html
*  Schizophrenia past clozapine: what works?
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*  Clozapine-induced maculopathy | The Medical Journal of Australia
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*  Clozapine-induced maculopathy | The Medical Journal of Australia
We thank Mack and Symons for their comments on our article.1 Our patient presented with bilateral asymmetric macular pigmentary changes, secondary to disturbances of the retinal pigment epithelium (RPE). Clinical examination findings corresponded with visual field and electrophysiology tests.. ...
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*  Serum Clozapine and Cognition - Tabular View - ClinicalTrials.gov
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*  Mortality in current and former users of clozapine | RTI
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