*  Chromosome 18 (human) - Wikipedia
Gilbert F (1997). "Disease genes and chromosomes: disease maps of the human genome. Chromosome 18". Genet Test. 1 (1): 69-71. ... The following is a partial list of genes on human chromosome 18. For complete list, see the link in the infobox on the right. ... The following are some of the gene count estimates of human chromosome 18. Because researchers use different approaches to ... People normally have two copies of this chromosome. Chromosome 18 spans about 80 million base pairs (the building material of ...
  https://en.wikipedia.org/wiki/Chromosome_18_(human)
*  Bacterial artificial chromosome - Wikipedia
"Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector ... Cosmid End-sequence profiling Fosmid Human artificial chromosome Yeast artificial chromosome O'Connor M, Peifer M, Bender W ( ... BACs can also be utilized to detect genes or large sequences of interest and then used to map them onto the human chromosome ... "Construction of a 750-kb bacterial clone contig and restriction map in the region of human chromosome 21 containing the ...
  https://en.wikipedia.org/wiki/Bacterial_artificial_chromosome
*  ROCK1 - Wikipedia
The human ROCK1 gene is located on human chromosome 18 with specific location of 18q11.1. The location of the base pair starts ... In humans, the main function of ROCK1 is actomyosin contractility. As mentioned before, this contributes to many proximal ... "Q13464 (ROCK1_HUMAN)". "Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and ... Therefore, increased expression of RhoA and its downstream effector ROCK1 is often observed in human cancers. These cancers are ...
  https://en.wikipedia.org/wiki/ROCK1
*  Haplogroup S1a (Y-DNA) - Wikipedia
Cox MP, Mirazón Lahr M (2006). "Y-chromosome diversity is inversely associated with language affiliation in paired Austronesian ... Haplogroup S1a is a human Y-DNA haplogroup, defined by SNPs Z41335, Z41336, Z41337, Z41338, Z41339, Z41340, and Z41341. S1a is ... European Journal of Human Genetics. 23. doi:10.1038/ejhg.2014.106. Kayser M, Choi Y, Van Oven M, Mona S, Brauer S, Trent RJ, ... "Improved phylogenetic resolution and rapid diversification of Y-chromosome haplogroup K-M526 in Southeast Asia". Eur J Hum ...
  https://en.wikipedia.org/wiki/Haplogroup_S1a_(Y-DNA)
*  Haplogroup S-M230 - Wikipedia
... genealogy Haplogroup Haplotype Human Y-chromosome DNA haplogroup Molecular phylogenetics Paragroup Subclade Y-chromosome ... "Y-chromosome diversity is inversely associated with language affiliation in paired Austronesian- and Papuan-speaking ... "Reduced Y-Chromosome, but Not Mitochondrial DNA, Diversity in Human Populations from West New Guinea". The American Journal of ... Haplogroup S-M230, also known as S1a1b (and previously as S* or K2b1a4), is a Y-chromosome DNA haplogroup. It is by far the ...
  https://en.wikipedia.org/wiki/Haplogroup_S-M230
*  Y-DNA haplogroups in populations of Oceania - Wikipedia
Y-chromosome haplotypes and implications for human history in the Pacific". Human Mutation. 17 (4): 271-80. doi:10.1002/humu.23 ... Cox, Murray P.; Mirazón Lahr, Marta (2006). "Y-chromosome diversity is inversely associated with language affiliation in paired ... by human Y-chromosome DNA haplogroups based on relevant studies. Oceania Languages of Oceania Demographics of Oceania List of ... "Reduced Y-Chromosome, but Not Mitochondrial DNA, Diversity in Human Populations from West New Guinea". The American Journal of ...
  https://en.wikipedia.org/wiki/Y-DNA_haplogroups_in_populations_of_Oceania
*  Marta Mirazón Lahr - Wikipedia
"Y-chromosome diversity is inversely associated with language affiliation in paired Austronesian- and Papuan-speaking ... She and Robert Foley were the first to propose a 'southern route' for humans out of Africa, and for human diversity to be the ... Lahr's research is in human evolution, and ranges across human and hominin morphology, prehistory and genetics. Her early work ... Lahr, M. M. & Foley, R. (1998). "Towards a theory of modern human origins: Geography, demography, and diversity in recent human ...
  https://en.wikipedia.org/wiki/Marta_Miraz%C3%B3n_Lahr
*  Haplogroup M-P256 - Wikipedia
Cox, Murray P.; Mirazón Lahr, Marta (2006). "Y-chromosome diversity is inversely associated with language affiliation in paired ... genetic genealogy Haplogroup Haplotype Human Y-chromosome DNA haplogroup molecular phylogeny Paragroup Subclade Y-chromosome ... "Reduced Y-Chromosome, but Not Mitochondrial DNA, Diversity in Human Populations from West New Guinea". The American Journal of ... Haplogroup M, also known as M-P256 and Haplogroup K2b1b (previously K2b1d) is a Y-chromosome DNA haplogroup. M-P256 is a ...
  https://en.wikipedia.org/wiki/Haplogroup_M-P256
*  Mothers against decapentaplegic homolog 4 - Wikipedia
In humans, the SMAD4 gene contains 54 829 base pairs and is located from pair n° 51,030,212 to pair 51,085,041 in the region ... In mammals, SMAD4 is coded by a gene located on chromosome 18. ... Somatic mutations found in human cancers of the MH1 domain of ... Zawel L, Dai JL, Buckhaults P, Zhou S, Kinzler KW, Vogelstein B, Kern SE (Mar 1998). "Human Smad3 and Smad4 are sequence- ... Martin MM, Buckenberger JA, Jiang J, Malana GE, Knoell DL, Feldman DS, Elton TS (Sep 2007). "TGF-beta1 stimulates human AT1 ...
  https://en.wikipedia.org/wiki/Mothers_against_decapentaplegic_homolog_4
*  ZIP9 - Wikipedia
... in the SLC39A9 gene can occur due to genetic deletion of the q24.1-24.3 band of base pairs within the human chromosome 14. This ... ZIP9 influxes zinc ions into the cytosol and its gene is expressed almost in every tissue of human body. The sub-cellular ... Role of human ZIP9 in testosterone-induced prostate and breast cancer cell apoptosis". Endocrinology. 155 (11): 4250-65. doi: ... A study in 2014, elucidated the intermediary role of ZIP9 in causing human breast and prostate cancer, as it induced the ...
  https://en.wikipedia.org/wiki/ZIP9
*  Western New Guinea - Wikipedia
Murray P. Cox and Marta Mirazón Lahr, "Y-Chromosome Diversity Is Inversely Associated With Language Affiliation in Paired ... Reduced Y-Chromosome, but Not Mitochondrial DNA, Diversity in Human Populations from West New Guinea Am J Hum Genet 72:281-302 ... Y-chromosome haplogroup M is the most common, with Y-chromosome haplogroup O2a as a small minority in second place and Y- ... Human habitation is estimated to have begun between 42,000 and 48,000 years ago. The Netherlands claimed the region and ...
  https://en.wikipedia.org/wiki/Western_New_Guinea
*  Human genetic variation - Wikipedia
Chromosome abnormalities are detected in 1 of 160 live human births. Apart from sex chromosome disorders, most cases of ... The human nucleotide diversity is estimated to be 0.1% to 0.4% of base pairs. A difference of 1 in 1,000 amounts to ... According to a 2000 study of Y-chromosome sequence variation, human Y-chromosomes trace ancestry to Africa, and the descendants ... No two humans are genetically identical. On average, in DNA sequence, each human is 99.5% similar to any other human. Even ...
  https://en.wikipedia.org/wiki/Human_genetic_variation
*  Base pair - Wikipedia
The haploid human genome (23 chromosomes) is estimated to be about 3.2 billion bases long and to contain 20,000-25,000 distinct ... The GU pairing, with two hydrogen bonds, does occur fairly often in RNA (see wobble base pair). Paired DNA and RNA molecules ... kb (= kbp) = kilo base pairs = 1,000 bp Mb (= Mbp) = mega base pairs = 1,000,000 bp Gb = giga base pairs = 1,000,000,000 bp. ... In the Human genome, the centimorgan is about 1 million base pairs. List of Y-DNA single-nucleotide polymorphisms Non-canonical ...
  https://en.wikipedia.org/wiki/Base_pair
*  RUFY2 - Wikipedia
The human RUFY2 gene is located on the long (q) arm of chromosome 10 at region 21 band 3, from base pair 70,100,864 to base ... RUN and FYVE domain containing 2 (RUFY2) is a protein that in humans is encoded by the RUFY2 gene. The RUFY2 gene is named for ... 8,180 base pairs upstream of RUFY2 is the protein-coding gene for phenazine biosynthesis-like protein domain containing (PBLD ... pair 70,167,051 on the reverse strand (Build GRCh37/hg19) (map). The gene produces a 2,080 base pair mRNA. There are 18 ...
  https://en.wikipedia.org/wiki/RUFY2
*  Duffy antigen system - Wikipedia
DARC protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) Duffy at BGMUT Blood Group Antigen ... The gene was first localised to chromosome 1 in 1968, and was the first blood system antigen to be localised. It is a single ... The mouse gene has two exons (100 and 1064 nucleotides in length respectively), separated by a 461 base pair intron. In the ... The ancestral form of extant DARC alleles in humans appears to be the FY*B allele. The gene appears to be under strong ...
  https://en.wikipedia.org/wiki/Duffy_antigen_system
*  Mendelian traits in humans - Wikipedia
The human Y chromosome is composed of about 59 million base pairs and is passed virtually unchanged from father to son. The ... Up to eighteen percent(18%) of children have a different father than what is believed and is called misattributed paternity. ... repair Electrophoresis Genetic disorder Heritability Human chromosomes Human genetic variation Human genetic clustering Human ... "First Human Embryos Edited in U.S." author Steve Connor. July 26, 2017 Gene editing used to correct sickle cell disease, human ...
  https://en.wikipedia.org/wiki/Mendelian_traits_in_humans
*  STAG3 (gene) - Wikipedia
... a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the ... "Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers". Proceedings of the National ... Stromal antigen 3 is a protein that in humans is encoded by the STAG3 gene. STAG3 protein is a component of a cohesin complex ... STAG3 appears to participate in sister-chromatid cohesion throughout the meiotic process in human oocytes. A homozygous 1-bp ...
  https://en.wikipedia.org/wiki/STAG3_(gene)
*  Chimpanzee genome project - Wikipedia
Humans have 23 pairs of chromosomes and other great apes have 24 pairs of chromosomes. In the human evolutionary lineage, two ... Human and chimpanzee chromosomes are very similar. The primary difference is that humans have one fewer pair of chromosomes ... Human evolutionary genetics Human chromosome 2 Human Genome Project McConkey EH (2004). "Orthologous numbering of great ape and ... producing human chromosome 2. There are nine other major chromosomal differences between chimpanzees and humans: chromosome ...
  https://en.wikipedia.org/wiki/Chimpanzee_genome_project
*  MiR-122 - Wikipedia
In humans, miR-122 is encoded at a single genomic locus in chromosome 18. The primary miR-122 transcript (pri-miR-122) is a ... The miR-122 hairpin precursor consensus shown here is predicted based on base pairing and cross-species conservation. The ... This molecule reduced HCV viremia in a small-scale trial in chimpanzees and was found to be safe in a small trial in humans. ... Lin CJ, Gong HY, Tseng HC, Wang WL, Wu JL (2008). "miR-122 targets an anti-apoptotic gene, Bcl-w, in human hepatocellular ...
  https://en.wikipedia.org/wiki/MiR-122
*  NDUFA6 - Wikipedia
The NDUFA6 gene is located on the q arm of chromosome 22 in position 13.2 and spans 5,359 base pairs. The gene produces an 18 ... Related pseudogenes have also been identified on four other chromosomes. The human NDUFA6 gene codes for a subunit of Complex I ... 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489-95. doi:10.1038/990031. PMID 10591208. Hattori M, ... 2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311-9. doi:10.1038/35012518. PMID 10830953. Strausberg RL ...
  https://en.wikipedia.org/wiki/NDUFA6
*  Human accelerated regions - Wikipedia
HAR1 is an 106-base pair stretch found on the long arm of chromosome 20 overlapping with part of the RNA genes HAR1F and HAR1R ... Human accelerated regions (HARs), first described in August 2006, are a set of 49 segments of the human genome that are ... "Comment on "Human-Specific Gain of Function in a Developmental Enhancer"". Science. February 6, 2009. What Makes Us Human?, ... They are named according to their degree of difference between humans and chimpanzees (HAR1 showing the largest degree of human ...
  https://en.wikipedia.org/wiki/Human_accelerated_regions
*  KIAA1841 - Wikipedia
The KIAA1841 gene spans 52809 base pairs and is orientated on the ++ strand. The coding region is made up of 4292 base pairs ... KIAA1841 is expressed at low levels in a wide range of tissues throughout the human body. In humans, the KIAA1841 gene produces ... Genes PEX13 and C2orf74 neighbor KIAA1841 on chromosome 2. KIAA1841 is highly expressed in reproductive structures and nervous ... "Genecards". The Gene Human Database. "Aceview". NCBI. "Genecards". The Gene Human Database. "BLAST". NCBI. Hedges, SB. " ...
  https://en.wikipedia.org/wiki/KIAA1841
*  Biomphalaria glabrata - Wikipedia
The chromosomes in this snail are small, and the haploid number of chromosomes is 18. A complete genome sequence from the ... 1997). The genome length is estimated as about 929,10 Mb (millions of base pairs; 0.95 ± 0.01 pg), which is a small genome size ... Sequencing of the whole genome was approved as a priority by National Human Genome Research Institute in August 2004, Its ... Crompton, D. W. (1999). "How much human helminthiasis is there in the world?" (PDF). The Journal of Parasitology. 85 (3): 397- ...
  https://en.wikipedia.org/wiki/Biomphalaria_glabrata
*  PAX4 - Wikipedia
Paired box gene 4, also known as PAX4, is a protein which in humans is encoded by the PAX4 gene. This gene is a member of the ... Tamura T, Izumikawa Y, Kishino T, Soejima H, Jinno Y, Niikawa N (1994). "Assignment of the human PAX4 gene to chromosome band ... Pilz AJ, Povey S, Gruss P, Abbott CM (1993). "Mapping of the human homologs of the murine paired-box-containing genes". ... Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes ...
  https://en.wikipedia.org/wiki/PAX4
*  Keratin 18 - Wikipedia
1997). "Mutation of human keratin 18 in association with cryptogenic cirrhosis". J. Clin. Invest. 99 (1): 19-23. doi:10.1172/ ... chromosomal location emphasizes difference from other keratin pairs". New Biol. 2 (5): 464-78. PMID 1705144. Romano V, Hatzfeld ... Waseem A, Gough AC, Spurr NK, Lane EB (1990). "Localization of the gene for human simple epithelial keratin 18 to chromosome 12 ... Detection of mRNAs encoding human cytokeratins nos. 8 and 18 in normal and tumor cells by hybridization with cDNA sequences in ...
  https://en.wikipedia.org/wiki/Keratin_18