*  Secreted Protein Acidic and Rich in Cysteines-like 1 Suppresses Aggressiveness and Predicts Better Survival in Colorectal...
The mRNA level of SPARCL1 was barely detectable in most of colorectal tumor cell lines including RKO and SW620 (Supplementary ... 106 viable tumor cells at the site of costal region. Tumor size was measured every 3 days. Tumor volume was calculated on the ... Cell culture and SPARCL1 expression plasmid transfection. Colon cancer cell lines (RKO and SW620) were obtained from American ... Laparotomy was conducted on all the mice at 40 days after the implantation of tumor cells. It revealed that RKO-pLXSN cells ...
  http://clincancerres.aacrjournals.org/content/18/19/5438?rss=1
*  Cell Death Identification in Anticancer Therapy-Response | Cancer Research
As it has been pointed out, the major form of cell death triggered in a cell culture relies on the genetics of tumor cells and ... Enter multiple addresses on separate lines or separate them with commas.. You are going to email the following Cell Death ... of tumor cells are active clonogenic cells, but less consensus is met when considering if those "cancer stem cells" constitute ... This setting keeps cell-to-cell and paracrine communications in closer degree than what would happen in actual tumors without ...
  http://cancerres.aacrjournals.org/content/early/2015/08/17/0008-5472.CAN-15-1540
*  Effect of Cav-1 expression in prostate cancer cells on | Open-i
Effect of Cav-1 expression in prostate cancer cells on in vitro lymphangiogenesis(A) LEC differentiation into tube-like ... Bottom Line: The effect of PCa cell conditioned media on lymphatic endothelial cell (LEC) viability, chemotaxis, chemokinesis ... Cav-1 is overexpressed in PCa, promotes prostate tumour progression and metastasis. We investigated the effect of caveolar and ... Bottom Line: The effect of PCa cell conditioned media on lymphatic endothelial cell (LEC) viability, chemotaxis, chemokinesis ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4549361_oncoscience-02-635-g004&req=4
*  2-Methoxyestradiol als neue Substanz zur Behandlung solider Tumore
... has a very strong growth inhibitory effect on cell lines from different solid cancer types. The tumors investigated were ... We found up to 90% growth inhibition in all cell lines with the exception of one pancreatic cancer cell line. This effect could ... growth inhibition due to 2-ME treatment was the induction of apoptosis in all cell lines except one pancreatic cancer cell line ... In one HCC cell line (SK-Hep1), which is the most sensitive to 2-ME, we found a down-regulation of the strongest anti-apoptosis ...
  https://edoc.hu-berlin.de/handle/18452/14592?C=N
*  CD146 suppresses breast tumor invasion via its novel downstream transcriptional target gene, TimpV | OncologyPRO
... the weakly and the highly invasive BC cell lines MCF-7 and MDA-MB-231, respectively. CD146/TimpV association was validated by ... CD146, a marker of endothelial cells, promotes tumor progression of many cancers including melanoma and the prostate. ... it is negatively regulated in melanoma cells, where increased CD146 inhibits TimpV to promote melanoma cell motility. ... 66P - CD146 suppresses breast tumor invasion via its novel downstream transcriptional target gene, TimpV. ...
  http://oncologypro.esmo.org/Topics/Breast-Cancer/CD146-suppresses-breast-tumor-invasion-via-its-novel-downstream-transcriptional-target-gene-TimpV
*  Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death | Cancer Research
Several cancer cell lines in the National Cancer Institute panel of 60 tumor cell lines, including MCF-7 and MDA-MB-231, ... Cells were stored in liquid nitrogen and used within 6 months after thawing. Cell lines were grown at 37°C in 5% CO2. MCF-7 ... Greater cell cycle inhibition and cytotoxicity induced by a 2-deoxy-D-glucose in tumor cells treated under hypoxic vs. aerobic ... Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin. Cancer Res 1987;47:2594-8. ...
  http://cancerres.aacrjournals.org/content/72/10/2634.long
*  Figure s1. Metformin (MET) effects on proliferation of various human cancer cell lines. Lung carcinoma cells (A549, H1299, SK...
Human lung embryonic fibroblast cell line was treated with an increasing concentrations of MET (0µmol-25µmol) for a period of ... Cells were subsequently fixed with ethanol and DNA content was used as a marker for proliferation rate determined by crystal ... Metformin (MET) effects on proliferation of human lung embryonic fibroblast cell line. ... Tumor Markers Lecture one By Dr. Reem Sallam. Objectives  To briefly introduce cancers, their incidence, some common terms, ...
  http://slideplayer.com/slide/684069/
*  Plus it
Cell lines. The human breast cancer cell lines DU4475, MDA-MB-231, and MDA-MB-435 and mouse myeloma cell lines P3-X63-Ag8.653 ... 3B) proliferation of hypoxic tumor cells in a dose response. A similar result was observed in treatment of the tumor cells with ... reduced tumor cell proliferation, and increased tumor cell apoptosis. Pharmacokinetic/pharmacodynamic studies established a ... Inhibition of tumor cell proliferation. Serum-starved DU4475 cells were treated with desferrioxamine followed by treatment with ...
  http://clincancerres.aacrjournals.org/content/12/21/6573
*  Plus it
It is overexpressed in a variety of primary tumor cell cultures and tumor cell lines (13, 15-18, 25, 34), whereas normal cells ... PM-RCC cell line). PM-RCC is renal cell carcinoma cell line that has been shown to express IL-13Rα2 chain (13). When breast ... A, RT-PCR analysis for IL-13Rα2 chain transcripts in breast cancer cell lines. Total RNA (2 μg) from five cell lines ... and from 1000 to 320 ng/ml in ZR-75-1 cell line, respectively. Using MCF-7 cell line, we also confirmed that the protein ...
  http://mct.aacrjournals.org/content/3/2/137
*  Plus it
... of such an approach is that the catalog of currently available cell lines is inevitably finite and possibly poor for some tumor ... The main reason for this inadequacy is an inherent difficulty in deriving long-term cell cultures from human tumors, which not ... Therefore, experiments with cell lines cannot recapitulate the wide heterogeneity of human malignancy that occurs among ... High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of ...
  http://cancerdiscovery.aacrjournals.org/content/1/6/508
*  Tumor Cells Deactivate Human Monocytes by Up-Regulating IL-1 Receptor Associated Kinase-M Expression via CD44 and TLR4 | The...
Human monocytes were cocultured with different tumor cell lines at a ratio of 1:0.3 (monocytes:tumor cells) for the times ... human hepatoblastoma cell line), and HeLa (human cervical tumor) provided by the American Type Culture. All cell lines were ... Fixed tumor cell lines and soluble factors from cultured cancer cells induce IRAK-M gene expression in human monocytes. To gain ... human breast carcinoma cell line), HL60 (human promyelocytic leukemia cell line), Jurkat (human T cell leukemia), HepG2 ( ...
  http://www.jimmunol.org/content/174/5/3032.long
*  Induction of apoptosis by polyamine metabolites in immunocompetent cells and different tumor cell lines | Arthritis Research &...
Induction of apoptosis by polyamine metabolites in immunocompetent cells and different tumor cell lines. ... and various tumor cell lines (Jurkat, SKW-3, U937). Moreover, DSG and Spm triggered apoptosis in human Fas-deficient cells and ... and PA-triggered glutathion depletion cause apoptosis in immunocompetent cells and apoptosis-resistant tumor cell lines. ... It is described that polyamines can induce apoptosis in mesenchymal cell lines. The aim of our study was to analyze whether the ...
  https://arthritis-research.biomedcentral.com/articles/10.1186/ar496
*  The Role for NES1 Serine Protease as a Novel Tumor Suppressor | Cancer Research
Similar to breast cancer cell lines, prostate cancer cell lines also lacked NES1 mRNA and protein expression. Together, these ... 231 breast cancer cell line suppressed the oncogenicity as revealed by inhibition of the anchorage-independent growth and tumor ... that is expressed in normal mammary epithelial cells but is down-regulated in most breast cancer cell lines. Here, we ... The Role for NES1 Serine Protease as a Novel Tumor Suppressor. Jaya Goyal, Karen M. Smith, Janet M. Cowan, David E. Wazer, Sam ...
  http://cancerres.aacrjournals.org/content/58/21/4782.long
*  Wilms' Tumour(tumor) cell lines
... Mr. D.M. Shaw incubus at liverpool.ac.uk Thu Jun 13 09:11:29 EST 1996 *Previous message: A260 ... Hi cell biologists, I am looking for tumour cell lines derived from childhood renal tumours such as Wilms' or the bone marrow ... metastasizing renal tumour of chilhood (BMRTC). Can anyone help? Please send replies vie E-mail incubus at liv.ac.uk Many ...
  http://www.bio.net/bionet/mm/methods/1996-June/045631.html
*  Vascular mimicry in cultured head and neck tumour cell lines.
... by which some genetically deregulated and aggressive tumour cells generat ... Vascuologenesis is the de novo establishment of blood vessels and vascular networks from mesoderm-derived endothelial cell ... cell lines and other aggressive tumour cell lines. We present experimental evidence of vasculogenic mimicry in HNSCC cell lines ... Metastatic HNSCC cells lines were found to have vasculogenic properties similar to HUVEC cell lines when compared to cell lines ...
  http://www.biomedsearch.com/nih/Vascular-mimicry-in-cultured-head/22196216.html
*  Atlas of Human Tumor Cell Lines | 9780123335302 | VitalSource
Buy or Rent Atlas of Human Tumor Cell Lines as an eTextbook and get instant access. With VitalSource, you can save up to 80% ... Atlas of Human Tumor Cell Lines Edition by Robert K.M. Hay and Publisher Academic Press. Save up to 80% by choosing the ...
  https://www.vitalsource.com/products/atlas-of-human-tumor-cell-lines-robert-k-m-hay-v9781483288628
*  Poly A+ RNA, mRNA from Human Tumors and Cell Lines
Cell Line. Poly A Plus RNA samples are enriched through two rounds of oligo(dT) chromatography. Representative populations with ... Human Cell Line ZR75-1 (Breast Carcinoma) Poly A+ RNA 5 ug $538.00 ... Human Cell Line HEP G2 (Hepatoblastoma) Poly A+ RNA 5 ug $538.00 ... Cell Biology * Measure Cell Proliferation. * Measure Cell Death ... Human Cell Line MCF7 (Breast Adenocarcinoma) Poly A+ RNA 5 ug $538.00 ...
  http://www.clontech.com/US/Products/cDNA_Synthesis_and_Library_Construction/RNA/Poly_A_Plus_RNA_Human/Cancer_and_Cell_Line?sitex=10020:22372:US&PROD=1Oq2jpVJto4Uy5ejthsazt3H:S&PROD_pses=ZGDD45B6EAF5C0F611CCCCD9230E168D554257911F27C3A592C132F1605D3BA6AB346B83D2EBD432CCF114AF5D19A3FE964BCCD8FCC3410A26
*  Poly A+ RNA, mRNA from Human Tumors and Cell Lines
Cell Line. Poly A Plus RNA samples are enriched through two rounds of oligo(dT) chromatography. Representative populations with ... Human Cell Line ZR75-1 (Breast Carcinoma) Poly A+ RNA 5 ug $517.00 ... Human Cell Line HEP G2 (Hepatoblastoma) Poly A+ RNA 5 ug $517.00 ... Human Stem Cell Derived Beta Cells * Human Stem Cell Derived ... Human Cell Line MCF7 (Breast Adenocarcinoma) Poly A+ RNA 5 ug $517.00 ...
  http://www.clontech.com/US/Products/cDNA_Synthesis_and_Library_Construction/RNA/Poly_A_Plus_RNA_Human/Cancer_and_Cell_Line?sitex=10020:22372:US&PEBCL1=EgywJCYu5xkKYJ0ltqKTYMJXTP&PEBCL1_pses=ZG9C350B6746E3CFF74C26E275501D41D1F0919BFB6056C7371C40EF44E7779F262EBCC3D289B192A4DF6ED0B8FA43DD390D1A66342065B0A9
*  List of breast cancer cell lines - Wikipedia
Cailleau R, Young R, Olivé M, Reeves WJ Jr (1974). "Breast tumor cell lines from pleural effusions". Journal of the National ... Lasfargues EY, Coutinho WG, Redfield ES (1978). "Isolation of two human tumor epithelial cell lines from solid breast ... 2006). "A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes". Cancer Cell. 10 (6): ... "Molecular Profiling of Breast Cancer Cell Lines Defines Relevant Tumor Models and Provides a Resource for Cancer Gene Discovery ...
  https://en.wikipedia.org/wiki/List_of_breast_cancer_cell_lines
*  Halichondrin B - Wikipedia
"NCI-60 DTP Human Tumor Cell Line Screen". Developmental Therapeutics Program, National Cancer Institute. Archived from the ... "60-cell line screen" The complete chemical synthesis of halichondrin B was achieved by Yoshito Kishi and colleagues at Harvard ... these authors also reported the exquisite anticancer activity of halichondrin B against murine cancer cells both in culture and ...
  https://en.wikipedia.org/wiki/Halichondrin_B
*  DAOY (biology) - Wikipedia
Sep 2003). "Protein profiles of medulloblastoma cell lines DAOY and D283: identification of tumor-related proteins and ... Sep 2016). "Top-down proteomic characterization of DAOY medulloblastoma tumor cell line". EuPA Open Proteomics. 12: 13-21. ... DAOY is a widely used human primary medulloblastoma cell line. It has epithelial morphology and was obtained from a 4-year-old ... Srivastava VK, Nalbantoglu J (Oct 2008). "Flow cytometric characterization of the DAOY medulloblastoma cell line for the cancer ...
  https://en.wikipedia.org/wiki/DAOY_(biology)
*  Tumor necrosis factor superfamily - Wikipedia
It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, ... FASL, a cell surface protein involved in cell death. 4-1BBL, an inducible T cell surface molecule that contributes to T-cell ... two related cytokines produced by lymphocytes that are cytotoxic for a wide range of tumor cells in vitro and in vivo. T cell ... The tumor necrosis factor (TNF) superfamily refers to a superfamily of cytokines that can cause cell death (apoptosis). The ...
  https://en.wikipedia.org/wiki/Tumor_necrosis_factor_superfamily
*  Interleukin 10 - Wikipedia
Expression of IL-10 from transfected tumor cell lines. in IL-10 transgenic mice. or dosing with IL-10 leads to control of ... mast cells, CD4+CD25+Foxp3+ regulatory T cells, and in a certain subset of activated T cells and B cells. IL-10 can be produced ... In melanoma cell lines, IL-10 modules the surface expression of NKG2D ligands. Knockout studies in mice suggested the function ... it is also stimulatory towards certain T cells (Th2) and mast cells and stimulates B cell maturation and antibody production. ...
  https://en.wikipedia.org/wiki/Interleukin_10
*  Myeloid-derived suppressor cell - Wikipedia
Tumor cell lines overexpressing colony stimulating factors (e.g. G-CSF and GM-CSF) have long been used in in vivo models of ... Similar to other myeloid cells, MDSCs interact with other immune cell types including T cells, dendritic cells, macrophages and ... These MDSCs infiltrate inflammation sites and tumors, where they stop immune responses by inhibiting T cells and NK cells, for ... MDSC (myeloid-derived suppressor cells) are a heterogenous group of immune cells from the myeloid lineage (a family of cells ...
  https://en.wikipedia.org/wiki/Myeloid-derived_suppressor_cell