*  Abstract 18478: Deletion of E2f1 Promotes Bone-marrow Progenitor Cell Differentiation and Ischemic Cardiac Repair | Circulation
Since an increase in oxidative phosphorylation in stem/progenitor cells is often associated with cell differentiation, we ... progenitor cells is markedly lower than those in WT cells (P,0.01, n=4). After culture in the EPC differentiation medium for 7 ... Abstract 18478: Deletion of E2f1 Promotes Bone-marrow Progenitor Cell Differentiation and Ischemic Cardiac Repair. Shiyue Xu, ... Abstract 18478: Deletion of E2f1 Promotes Bone-marrow Progenitor Cell Differentiation and Ischemic Cardiac Repair ...
  http://circ.ahajournals.org/content/130/Suppl_2/A18478
*  Pleiotrophin antagonizes Bromodomain-containing protein 2 (Brd2) during neuronal differentiation | Journal of Cell Science
To shed light on the role of Brd2 in the transition from cell proliferation to differentiation we have looked for Brd2 ... Ptn-mediated antagonism of Brd2 has been assessed in a cell differentiation model and in two embryonic processes associated ... The splicing co-factor Barricade/Tat-SF1 is required for cell cycle and lineage progression in Drosophila neural stem cells. ... on cell motility. A Travelling Fellowship from Journal of Cell Science allowed her to spend time in Prof Maddy Parson's lab at ...
  http://jcs.biologists.org/content/early/2014/03/31/jcs.147462
*  OPC differentiation assay<...
Following 5 days of differentiation, cells are stained and imaged in high-content ArrayScan™ reader in multiple channels. ... OPC differentiation assay. Renovo's OPC differentiation assay is used to identify compounds that promote the production of ... Cells were imaged in a high-content ArrayScan reader using a 10x objective. Green, PLP-EGFP+ oligodendrocytes; blue, Hoechst- ... Differentiation of OPCs into EGFP+ oligodendrocytes: CTL, no treatment; T3, treatment with thyroid hormone T3. OPCs were ...
  http://www.renovoneural.com/services/cell-based-assays/opc-differentiation-assay/
*  Cardiogenic Differentiation and Transdifferentiation of Progenitor Cells | Circulation Research
Cell-to-cell connection of endothelial progenitor cells with cardiac myocytes by nanotubes: a novel mechanism for cell fate ... bone marrow stem cell; VSESC, very small embryonic stem cell-like stem cell; EGS, embryonic germ cells. ... Cardiac differentiation has been reported for a variety of stem cell types, including both expected and unexpected cell types. ... Stem cells are clonogenic cells capable of both self-renewal and differentiation into more specialized progeny. Traditionally, ...
  http://circres.ahajournals.org/content/103/10/1058
*  β-Catenin signaling is required for neural differentiation of embryonic stem cells | Development
Neural differentiation of ES cells is regulated by cell density. ES cells were induced to differentiate by the 4-/4+ protocol ... Cells were seeded at high (106 cells/ml, HD) or low densities (105 cells/ml, LD) and treated with or without RA (cells in ... Cell density. Introduction. Embryonic stem (ES) cells are pluripotent cells derived from the inner cell mass of the blastocyst ... Neural differentiation of ES cells is inhibited at high density. To define the effects of cell density on neuronal lineage ...
  http://dev.biologists.org/content/131/15/3545
*  Breastmilk is a Novel Source of Stem Cells with Multilineage Differentiation Potential
... News Oct 12, 2012 ... They also highlight the potential of these cells to be used as novel models to understand adult stem cell plasticity and breast ... Here, we demonstrate that human breastmilk contains stem cells (hBSCs) with multilineage properties. Breastmilk cells from ... Mesenchymal Stem Cells can be Harvested from Amniotic Fluid During Caesareans News A team of scientists and clinicians at Lund ...
  https://www.technologynetworks.com/cell-science/news/breastmilk-is-a-novel-source-of-stem-cells-with-multilineage-differentiation-potential-189237
*  iPSC to Hepatocyte Differentiation System Overview
The process of generating hiPS cell-derived hepatocytes begins with the directed differentiation of hiPS cells into definitive ... Functional, disease-specific hepatocytes from patient-derived cell lines. The Cellartis iPS Cell to Hepatocyte Differentiation ... undifferentiated stem cell population is ideal. The iPS Cell to Hepatocyte Differentiation System promotes high-quality ... hiPS cells were differentiated into functional hepatocytes using the Cellartis iPS Cell to Hepatocyte Differentiation System. ...
  http://www.clontech.com/US/Products/Stem_Cell_Research/Resources/iPS_to_Hepatocyte_Differentiation_Overview?sitex=10020:22372:US&PEBCL1=q8DIRG9bPvMbTPhbC49c9ONqG5&PEBCL1_pses=ZG7AFC907621D7D9B47296560AA304D443226DB8FD4546DE161C4122758BE6DAF83AA0A21DAD20AEFF0C559D6E161D0F78B40BF35311019719
*  Movassagh M and Philpott A (2008), Cardiac differentiation in Xenopus requires the... - Xenbase Paper
We show that cell-cycling post-gastrulation is not essential for cardiac differentiation in Xenopus embryos, and conversely ... Figure 5. The requirement for Xic1 in cardiomyocyte differentiation is distinct from its ability to arrest the cell cycle. ... plays a role in neuronal and myotome differentiation beyond its ability to arrest the cell cycle. Thus, we investigated whether ... these results suggest that CDKIs play an important direct role in driving cardiomyocyte differentiation in addition to cell- ...
  http://www.xenbase.org/literature/article.do?method=display&articleId=37634
*  The Wnt/β-catenin pathway directs neuronal differentiation of cortical neural precursor cells | Development
The cells were incubated for 2 days with Fgf2, and the percentage of TuJ1+ cells among GFP+ cells was determined. *P, 0.02 and ... The cells were then incubated for 3 days in the absence of Fgf2. (A) The percentage of TuJ1+ cells among GFP+ cells was ... cell number (Fig. 2A). Most of the TuJ1- cells were Nestin+ and when the cells were cultured 3 days longer, many of them became ... DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Dev. Cell 1,749 -758. ...
  http://dev.biologists.org/content/131/12/2791
*  Telomere Length Influences Cancer Cell Differentiation
... promotes the differentiation of cancer cells, probably reducing malignancy, which is strongly associated with a loss of cell ... differentiation. They report their findings in a manuscript published online ahead of print, in the journal Molecular and ... promotes the differentiation of cancer cells, probably reducing malignancy, which is strongly associated with a loss of cell ... Cancer cells have shorter telomeres compared to healthy cells, but they guard their immortality by maintaining these telomeres ...
  https://www.asm.org/index.php/asm-newsroom/journal-tip-sheets/88-news-room/journal-tipsheets/91725-telomere-length-influences-cancer-cell-differentiation
*  Frontiers | Regulators of Tfh Cell Differentiation | Immunology
Tfh cells are also generated from the conversion of other effector T cells as exemplified by Th1 cells converting into Tfh ... Tfh cells are also generated from the conversion of other effector T cells as exemplified by Th1 cells converting into Tfh ... Tfh cells are generated from naïve CD4 T cells with sequential steps involving cytokine signaling (IL-21, IL-6, IL-12, activin ... Tfh cells are generated from naïve CD4 T cells with sequential steps involving cytokine signaling (IL-21, IL-6, IL-12, activin ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2016.00520/full
*  Phys.org - stem cell differentiation
Phys.org internet news portal provides the latest news on science including: Physics, Space Science, Earth Science, Health and Medicine
  https://phys.org/tags/stem+cell+differentiation/sort/liverank/1w/
*  Cell differentiation - Biology-Online Dictionary
It is the process in which a cell changes into another cell type. During cell differentiation, the changes may include cell ... A cell that underwent differentiation is described as differentiated. A differentiated cell means a cell that has changed in ... Cell differentiation refers to the normal process by which a less specialized cell goes through development and maturation in ... An undifferentiated cell therefore would be a primitive cell or a progenitor cell that is yet to undergo cellular ...
  https://www.biology-online.org/dictionary/Cell_differentiation
*  Dissecting teleost B cell differentiation using transcription factors.
In the absence of serological reagents, an alternative approach to dissecting teleost B cell development is to use ... B cell developmental pathways in teleost fishes are poorly understood. ... Cell Differentiation / genetics, immunology. Cell Separation. Fishes / immunology. Flow Cytometry. Gene Expression Regulation, ... B cell developmental pathways in teleost fishes are poorly understood. In the absence of serological reagents, an alternative ...
  http://www.biomedsearch.com/nih/Dissecting-teleost-B-cell-differentiation/21251922.html
*  Scientists Map Epigenetic Changes During Blood Cell Differentiation - 08/16/2010
... a Johns Hopkins-led team of scientists has produced the first-ever epigenetic landscape map for tissue differentiation. ... Having charted the occurrence of a common chemical change that takes place while stem cells decide their fates and progress ... Scientists Map Epigenetic Changes During Blood Cell Differentiation. Potential Application For Stem Cell Therapies ... The team could tell which types of stem cells the blood cells had come from, because epigenetically those blood cells had not ...
  https://www.hopkinsmedicine.org/news/media/releases/scientists_map_epigenetic_changes_during_blood_cell_differentiation
*  Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation | Nature Immunology
T cell differentiation, regulated the formation of terminal-effector cell fates and memory-precursor cell fates, respectively. ... Differentiation and persistence of memory CD8+ T cells depend on T cell factor 1. . Immunity 33, 229-240 (2010). ... T cell differentiation. *Bingfei Yu1. n2*, Kai Zhang ORCID: orcid.org/0000-0003-3454-73572. n2*, J Justin Milner1. *, Clara ... YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity. . Nat. Commun. 7, ...
  http://www.nature.com/articles/ni.3706?error=cookies_not_supported&code=c6e39a06-ad79-4ec5-8873-ead56d59bfc6
*  Interplay of matrix stiffness and protein tethering in stem cell differentiation. - PubMed - NCBI
Interplay of matrix stiffness and protein tethering in stem cell differentiation.. Wen JH1, Vincent LG1, Fuhrmann A2, Choi YS1 ... Our findings imply that the stiffness of planar matrices regulates stem cell differentiation independently of protein tethering ... osteogenic and adipogenic differentiation of human adipose-derived stromal cells and marrow-derived mesenchymal stromal cells. ... also regulates stem cell differentiation. By modulating substrate porosity without altering stiffness in polyacrylamide gels, ...
  https://www.ncbi.nlm.nih.gov/pubmed/25108614?access_num=25108614&link_type=MED&dopt=Abstract
*  IFN-β Inhibits Human Th17 Cell Differentiation | The Journal of Immunology
IFN-β-1a directly inhibits Th17 cell differentiation. A direct effect of IFN-β-1a on Th17 cell differentiation was investigated ... IFN-β-1a directly inhibits Th17 cell differentiation. A, IFN-β-1a inhibits RORc gene expression in CD4+CD45RA+ T cells cultured ... Dendritic cells transduced with SOCS-3 exhibit a tolerogenic/DC2 phenotype that directs type 2 Th cell differentiation in vitro ... and the Th17 cell surface marker IL-23R. The IFN-β-1a-mediated suppression of Th17 cell differentiation is also supported by ...
  http://www.jimmunol.org/content/183/8/5418?ijkey=7ddbecc251ce7249d4f5f8fcd06fdb702cf45964&keytype2=tf_ipsecsha
*  The Mesenchyme Controls the Timing of Pancreatic β-Cell Differentiation | Diabetes
... a master gene controlling endocrine cell-fate decisions in progenitor cells; then β-cell differentiation occurred. In the ... If differentiation occurs too early, the stem-cell pool remains small, and the final number of differentiated cells is ... β-cells did not develop (Figs. 4A, b and 7B, b). These results indicate that the mesenchyme modulates β-cell differentiation ... β-cell differentiation occurred, and the number of β-cells increased, as shown by in situ hybridization (Fig. 1A-E). Here, we ...
  http://diabetes.diabetesjournals.org/content/55/3/582
*  Tumor Cell Differentiation | Journal of Clinical Pathology
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center's RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
  http://jcp.bmj.com/content/41/4/480.3
*  JCI - Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation
Here, we show that expression of SPDEF or FOXA3 in airway epithelial cells in neonatal mice caused goblet cell differentiation ... SPDEF was required for goblet cell differentiation and pulmonary Th2 inflammation in response to house dust mite (HDM) extract ... Together, our results indicate that SPDEF causes goblet cell differentiation and Th2 inflammation during postnatal development ... where they regulate goblet cell differentiation and mucus production. Moreover, these transcription factors are upregulated in ...
  https://www.jci.org/articles/view/79422/pdf
*  miR-186 inhibits muscle cell differentiation through myogenin regulation. | Sigma-Aldrich
miR-186 inhibits muscle cell differentiation through myogenin regulation.. [Antonis Antoniou, Nikolaos P Mastroyiannopoulos, ... Functional studies demonstrated that miR-186 overexpression inhibited the differentiation of C2C12 and primary muscle cells. ... The complex process of skeletal muscle differentiation is organized by the myogenic regulatory factors (MRFs), Myf5, MyoD, Myf6 ... Our findings therefore identify miR-186 as a novel regulator of myogenic differentiation. ...
  https://www.sigmaaldrich.com/catalog/papers/24385428
*  Regulation of adipose stromal-vascular cell differentiation in culture
Differentiation of S-V cells was found to be under hormonal control. Insulin and glucocorticoids are essential for S-V cell ... Rat and pig S-V cells have different morphology when differentiated. Differentiated rat S-V cells appeared as individual cells ... of both sera inhibited differentiation and lipid filling in cultures of S-V cells but only rat fraction three promoted cell ... fasted pig sera stimulated greater differentiation and decreased cell replication as indicated by DNA content of rat S-V cell ...
  https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/pc289m34v
*  CiNii 論文 - Akt-FOXO3a Signaling Affects Human Endothelial Progenitor Cell Differentiation ...
Akt-FOXO3a Signaling Affects Human Endothelial Progenitor Cell Differentiation * * MOGI Masaki * Department of Molecular ... Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors ... Myogenic stem cell function is impaired in mice lacking the forkhead/winged helix protein MNF GARRY DJ ... Foxo3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1 BAKKER WJ ...
  https://ci.nii.ac.jp/naid/10021261462