*  Abstract 18478: Deletion of E2f1 Promotes Bone-marrow Progenitor Cell Differentiation and Ischemic Cardiac Repair | Circulation
Since an increase in oxidative phosphorylation in stem/progenitor cells is often associated with cell differentiation, we ... progenitor cells is markedly lower than those in WT cells (P,0.01, n=4). After culture in the EPC differentiation medium for 7 ... Abstract 18478: Deletion of E2f1 Promotes Bone-marrow Progenitor Cell Differentiation and Ischemic Cardiac Repair. Shiyue Xu, ... Abstract 18478: Deletion of E2f1 Promotes Bone-marrow Progenitor Cell Differentiation and Ischemic Cardiac Repair ...
  http://circ.ahajournals.org/content/130/Suppl_2/A18478
*  A new class of stem cells in South Africa: iPS cells
How are iPS cells made?. When cell differentiation occurs, the cell follows a process of changes in gene activity whereby ... The end result of this differentiation 'programme' is a specialised cell of one type or another (e.g. cardiac muscle cells or ... iPS cells have been derived from a wide range of cell types and differentiated into an equally broad range of cell types ... Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell ...
  http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742013000100012&lng=es&nrm=iso&tlng=en
*  Pleiotrophin antagonizes Bromodomain-containing protein 2 (Brd2) during neuronal differentiation | Journal of Cell Science
To shed light on the role of Brd2 in the transition from cell proliferation to differentiation we have looked for Brd2 ... Ptn-mediated antagonism of Brd2 has been assessed in a cell differentiation model and in two embryonic processes associated ... The splicing co-factor Barricade/Tat-SF1 is required for cell cycle and lineage progression in Drosophila neural stem cells. ... on cell motility. A Travelling Fellowship from Journal of Cell Science allowed her to spend time in Prof Maddy Parson's lab at ...
  http://jcs.biologists.org/content/early/2014/03/31/jcs.147462
*  OPC differentiation assay<...
Following 5 days of differentiation, cells are stained and imaged in high-content ArrayScan™ reader in multiple channels. ... OPC differentiation assay. Renovo's OPC differentiation assay is used to identify compounds that promote the production of ... Cells were imaged in a high-content ArrayScan reader using a 10x objective. Green, PLP-EGFP+ oligodendrocytes; blue, Hoechst- ... Differentiation of OPCs into EGFP+ oligodendrocytes: CTL, no treatment; T3, treatment with thyroid hormone T3. OPCs were ...
  http://www.renovoneural.com/services/cell-based-assays/opc-differentiation-assay/
*  Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation. | CHAVI-ID
Bcl6 is required for CD4 T cell differentiation into T follicular helper cells (Tfh). In this study, we examined the role of IL ... Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation.. Thu, 05/16/ ... IL-6 mediated STAT3 activation is important for downregulation of IL-2Rα to limit Th1 cell differentiation in an acute viral ... Home » Cutting edge: STAT1 is required for IL-6-mediated Bcl6 induction for early follicular helper cell differentiation. ...
  http://chavi-id.org/publications/cutting-edge-stat1-required-il-6-mediated-bcl6-induction-early-follicular-helper-cell
*  Inhibition of T cell differentiation into effectors by NKT cells requires cell contacts. - The Kennedy Institute of Rheumatology
... play only a minor role if any in the blockade of T cell differentiation by NKT cells. Diabetes is still prevented by NKT cells ... to determine the respective role of cytokines and cell contacts in the blockade of T cell differentiation by NKT cells. These ... cells inhibit the development of type 1 diabetes by impairing the differentiation of anti-islet T cells into Th1 effector cells ... In contrast, we show for the first time that cell contacts are crucial for the immunoregulatory function of NKT cells. ...
  https://www.kennedy.ox.ac.uk/publications/55303
*  Integrins regulate epithelial cell differentiation by modulating Notch activity | Journal of Cell Science
However, in some cell types, a modified cell cycle occurs during differentiation, in which the DNA is replicated without ... 2007). A double-assurance mechanism controls cell cycle exit upon terminal differentiation in Drosophila. Dev. Cell 12, 631-643 ... The processes of cell proliferation and differentiation have been studied independently, but the cell cycle is intimately ... The coordination of cell proliferation with the gradual differentiation of different cell types is essential for proper ...
  http://jcs.biologists.org/content/127/21/4667
*  β-Catenin signaling is required for neural differentiation of embryonic stem cells | Development
Neural differentiation of ES cells is regulated by cell density. ES cells were induced to differentiate by the 4-/4+ protocol ... Cells were seeded at high (106 cells/ml, HD) or low densities (105 cells/ml, LD) and treated with or without RA (cells in ... Cell density. Introduction. Embryonic stem (ES) cells are pluripotent cells derived from the inner cell mass of the blastocyst ... Neural differentiation of ES cells is inhibited at high density. To define the effects of cell density on neuronal lineage ...
  http://dev.biologists.org/content/131/15/3545
*  E2F4 Modulates Differentiation and Gene Expression in Hematopoietic Progenitor Cells during Commitment to the Lymphoid Lineage ...
... fetal liver cells to differentiation from cells corresponding to multilineage stem cells (the LSK cells) to cells corresponding ... Reconstitution analysis for LSK cells, CLP-like cells, CMP-like cells, DN1 thymocytes, pre-B and pro-B cells, GMP-like cells, ... LSK cells and CLP-like cells from reconstituted mice were sorted using a FACSAria cell sorter (BD Biosciences). Cells were ... cells, e2f4+/− (CD45.2+) cells mixed with e2f4+/+ (CD45.1+) cells, or e2f4−/− (CD45.2+) cells mixed with e2f4+/+ (CD45.1+) ...
  http://www.jimmunol.org/content/180/6/3699.long
*  springerlink, sciencedirect, wileyinterscience, z8OoqYUZwowyMHOpM6SRMRM1M0c: Three differentiation states risk-stratify bladder...
We investigated whether a molecular classification of tumor cell differentiation, based on a developmental biology approach, ... Three differentiation states risk-stratify bladder cancer into distinct subtypes. *Jens-Peter Volkmera,b,c,1,2, ... iDepartment of Molecular and Cellular Biology, Dan L. Duncan Cancer Center, Center for Cell Gene and Therapy, Baylor College of ... Our data indicate that BC can be subclassified into three subtypes, on the basis of their differentiation states: basal, ...
  http://journalaccess.blogspot.com/2012/02/three-differentiation-states-risk.html
*  iPSC to Hepatocyte Differentiation System Overview
The process of generating hiPS cell-derived hepatocytes begins with the directed differentiation of hiPS cells into definitive ... Functional, disease-specific hepatocytes from patient-derived cell lines. The Cellartis iPS Cell to Hepatocyte Differentiation ... undifferentiated stem cell population is ideal. The iPS Cell to Hepatocyte Differentiation System promotes high-quality ... hiPS cells were differentiated into functional hepatocytes using the Cellartis iPS Cell to Hepatocyte Differentiation System. ...
  http://www.clontech.com/US/Products/Stem_Cell_Research/Resources/iPS_to_Hepatocyte_Differentiation_Overview?sitex=10020:22372:US&PEBCL1=q8DIRG9bPvMbTPhbC49c9ONqG5&PEBCL1_pses=ZG7AFC907621D7D9B47296560AA304D443226DB8FD4546DE161C4122758BE6DAF83AA0A21DAD20AEFF0C559D6E161D0F78B40BF35311019719
*  Functional characterization of Nurr1 and Pin1 in neuronal progenitor cell differentiation | ScholarBank@NUS
neuronal progenitor cell (NT2/D1), differentiation, Nurr1, cell cycle, Pin1, dopaminergic neuron. ... However, the mechanism by which Nurr1 promotes dopamine cell differentiation has remained unknown. In this study, I have used a ... DONG BEIBEI (2006-02-28). Functional characterization of Nurr1 and Pin1 in neuronal progenitor cell differentiation. ... and Pin1 was identified and the possible mechanism whereby Pin1 affects the progression of cell cycle and cell differentiation ...
  http://scholarbank.nus.edu.sg/handle/10635/15062
*  Movassagh M and Philpott A (2008), Cardiac differentiation in Xenopus requires the... - Xenbase Paper
We show that cell-cycling post-gastrulation is not essential for cardiac differentiation in Xenopus embryos, and conversely ... Figure 5. The requirement for Xic1 in cardiomyocyte differentiation is distinct from its ability to arrest the cell cycle. ... plays a role in neuronal and myotome differentiation beyond its ability to arrest the cell cycle. Thus, we investigated whether ... these results suggest that CDKIs play an important direct role in driving cardiomyocyte differentiation in addition to cell- ...
  http://www.xenbase.org/literature/article.do?method=display&articleId=37634
*  Reduction of Prep1 Levels Affects Differentiation of Normal and Malignant B Cells and Accelerates Myc Driven Lymphomagenesis -...
Reduction of Prep1 Levels Affects Differentiation of Normal and Malignant B Cells and Accelerates Myc Driven Lymphomagenesis ... Moreover, we show that Prep1 is in fact required for the differentiation of Pro-B and Pre-B cells into IgM+ lymphocytes and-or ... Reduction of Prep1 Levels Affects Differentiation of Normal and Malignant B Cells and Accelerates Myc Driven Lymphomagenesis. ... Reduction of Prep1 Levels Affects Differentiation of Normal and Malignant B Cells and Accelerates Myc Driven Lymphomagenesis - ...
  http://libros.duhnnae.com/2017/jun7/149818268845-Reduction-of-Prep1-Levels-Affects-Differentiation-of-Normal-and-Malignant-B-Cells-and-Accelerates-Myc-Driven-Lymphomagenesis.php
*  The Wnt/β-catenin pathway directs neuronal differentiation of cortical neural precursor cells | Development
The cells were incubated for 2 days with Fgf2, and the percentage of TuJ1+ cells among GFP+ cells was determined. *P, 0.02 and ... The cells were then incubated for 3 days in the absence of Fgf2. (A) The percentage of TuJ1+ cells among GFP+ cells was ... cell number (Fig. 2A). Most of the TuJ1- cells were Nestin+ and when the cells were cultured 3 days longer, many of them became ... DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Dev. Cell 1,749 -758. ...
  http://dev.biologists.org/content/131/12/2791
*  The Neurocritic: February 2008
Stem Cells for Peter's McStroke Fig 3 (Daadi et al., 2008). Dispersion, engraftment and differentiation of the hNSCs [human ... Stem cells helped repair stroke damage in rats, early Stanford study shows. By AMY ADAMS. STANFORD, Calif. - Neural cells ... BACKGROUND: Human embryonic stem cells (hESCs) offer a virtually unlimited source of neural cells for structural repair in ... 2008). Adherent self-renewable human embryonic stem cell-derived neural stem cell line: functional engraftment in experimental ...
  http://neurocritic.blogspot.hu/2008/02/
*  Directed differentiation - Wikipedia
Cell differentiation involves a transition from a proliferative mode toward differentiation mode. Directed differentiation ... Proper differentiation of the cell type of interest is verified by analyzing cell type specific markers, gene expression ... It is essentially harnessing the potential of stem cells by constraining their differentiation in vitro toward a specific cell ... co-culture with stromal cells or feeder cells, and on specific culture substrates: support cells and matrices provide ...
  https://en.wikipedia.org/wiki/Directed_differentiation

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*  Facial Development Newsletter: July 2009
... cells that act as adult stem cells, and can produce osteoblasts, osteoclasts and fibroblasts. The receptors in the PDL let us ... There is an increase in cAMP (cyclic adenosine monophosphate) and cellular differentiation begins within the PDL. ... The PDL contains nerve fibers (receptors) blood vessels and mesenchymal cells that are undifferentiated, or partly ... are detected by mechanoreceptors on the surface of the periodontal and periosteal cells. When the light forces are applied to ...
  http://facialdevelopment.blogspot.com/2009/07/
*  Efficacy of Endoscopic Mucosal Resection after Circumferential Mucosal Incision of Small Rectal Carcinoid Tumors | OMICS...
... histopathological differentiation, muscular invasion, and lymphovascular invasion [7,20]. Among these factors, tumor size was a ... Pancreatic Islet Cell Cancer * Pancreatitis * Pancreatitis Symptoms * Partial Hepatectomy * Portal Hypertension * Proton ...
  https://www.omicsonline.org/efficacy-of-endoscopic-mucosal-resection-after-circumferential-mucosal-incision-of-small-rectal-carcinoid-tumors-2161-069X.S6-006.php?aid=12323
*  Dienekes' Anthropology Blog: 02/2013
... but some cells in the body divide much more frequently and so may rack up many more mutations. Other cells, like brain cells, ... The publication of Tianyuan has shown that by ~40kya, differentiation of Asians from Europeans was already on its way, and this ... While that may seem like a high accuracy rate, cells in the body divide trillions of times. So that would mean an average twin ... One limitation of the study is that they could only estimate the mutation rate based on blood cells, ...
  http://dienekes.blogspot.com/2013_02_01_archive.html?m=0
*  JCI - Welcome
Recombinant adiponectin blocked fat cell formation in long-term bone marrow cultures and inhibited the differentiation of ... β cell regeneration from islet cell precursors might reverse this disease, but factors that can induce β cell neogenesis and ... β cell mass increased in parallel as a result of neogenesis and β cell replication. Thus, our results indicate that local ... Furthermore, adiponectin failed to block fat cell generation when bone marrow cells were derived from B6,129SPtgs2tm1Jed (COX- ...
  https://www.jci.org/tags/20?content=articles&page=17
*  SiNAPSA | eNevron | posta|Kongres nevrologov Srbije
Hands-on course Human pluripotent stem cell culture (iPSC/ESC) and neural differentiation. Andraž Matkovič , 11. 6. 2017 ...
  http://www.sinapsa.org/enevron/posta/2011-02-28/265/Kongres_nevrologov_Srbije
*  Forum MikroskopieTrends ´16: Von der Probe zum digitalen Modell « Quantum Related Diseases Research Group (QRDRG)
Altern Bakterien blood brain breast cancer cancer cancer cells cancer risk cancer therapy cell chemotherapy Chromosom CT Demenz ... A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation. ... About metabolism of a carcinoma cell. Most cancer cells utilize aerobic glycolysis irrespective of their tissue of origin. The ... Every day, billions of new blood cells are generated in the bone marrow. The gene Myc is known to play an important role in ...
  http://diseasesresearchgroup.xonl.de/2016/12/01/forum-mikroskopietrends-16-von-der-probe-zum-digitalen-modell/
*  PerCP Anti-Human CD2 (RPA-2.10) Flow Cytometry Reagents, Recombinant Proteins, PCR Reagents
Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York. ... a subset of NK cells, and all mature T cells. CD2 mediates lymphocyte adhesion and is involved in T cell activation. ... CD2, also known as LFA-2, is a receptor for CD58 in the human and is expressed on the cell surface of 80-90% of human ... LFA-2, T11, Sheep Red Blood Cell Receptor (SRBC-R), Ly-37. ...
  https://www.tonbobio.com/antibodies-and-reagents/percp-anti-human-cd2-rpa-2-10.html
*  JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
This includes differentiation from a stem cell population, mitotic amplification, and meiosis. In addition, post-meiotic germ ... Two-photon imaging of immune cells requires that the cells are fluorescently labeled, either by staining with a cell tracker ... imaging of T-cell interaction with tumor cells and tumor cells migration along the collagen IV of basement membrane. Taken ... Neural stem/precursor cells (NPCs) are a promising stem cell source for transplantation approaches aiming at brain repair or ...
  https://www.jove.com/visualize/abstract/23300962/long-term-in-vivo-imaging-of-multiple-organs-at-the-single-cell-level