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*  What are the morphologic features of cells undergoing dedifferentiation - Stem Cell
What is the source of your epithelial cell? The morphology cannot certify that a cell is undergoing de-differentiation. You ... What is the source of your epithelial cell? The morphology cannot certify that a cell is undergoing de-differentiation. You ... if you find and prove the dedifferentiation of special cells, you may deserve a big paper!! QUOTE (Fetus @ Mar 10 2006, 08:28 ... What are the morphologic features of cells undergoing dedifferentiation - (Feb/24/2006 ). Hello All,. Could someone tell me ...
  http://www.protocol-online.org/biology-forums/posts/14029.html
*  Role of endothelial cell denudation and smooth muscle cell dedifferentiation in neointimal formation of human vein grafts after...
Spindle shaped cells and round cells at the response site are positive. (D) HHF-35. The spindle shaped cells and round cells ... Role of endothelial cell denudation and smooth muscle cell dedifferentiation in neointimal formation of human vein grafts after ... Role of endothelial cell denudation and smooth muscle cell dedifferentiation in neointimal formation of human vein grafts after ... Both spindle shaped cells and round cells in the neointima are positive. (C) HHF-35. The cells in the neointima do not stain. ( ...
  http://heart.bmj.com/content/83/1/69
*  JCI Insight - Virus-like infection induces human β cell dedifferentiation
Lastly, we identified SOX9 targets in human β cells as potentially new markers of dedifferentiation in T1D. These findings ... We undertook this study to examine whether viral infection could induce human β cell dedifferentiation. Using the functional ... EndoC-βH1 cells were treated with proinflammatory cytokines (TNF-α, IL-1β, and IFN-γ). (. A. ) SOX9. , HES1. , MYC. , MAFA. , ... EndoC-βH1 cells were transfected with control nontarget siRNA (siCTRL) or siRNA targeting RELA (siRELA). They were next treated ...
  https://insight.jci.org/articles/view/97732/figure/4
*  JCI Insight - Usage information: Virus-like infection induces human β cell dedifferentiation
Lastly, we identified SOX9 targets in human β cells as potentially new markers of dedifferentiation in T1D. These findings ... We undertook this study to examine whether viral infection could induce human β cell dedifferentiation. Using the functional ... SOX9 was induced by the NF-κB pathway and also in a paracrine non-cell-autonomous fashion through the secretion of IFN-α. ... Recent data suggest that viral infection of human islets leads to a decrease in insulin production rather than β cell death, ...
  https://insight.jci.org/articles/view/97732/usage
*  Stem Cell Dedifferentiation
More from: Stem Cell Dedifferentiation. TOR (focus on of rapamycin) can be an evolutionarily conserved nutrient. P April 28, ... Objective To examine the frequency and phenotype of Th17 cells in * Wig-1 is definitely a transcriptional target of the tumor ... Objective To examine the frequency and phenotype of Th17 cells in * Wig-1 is definitely a transcriptional target of the tumor ... evolutionarily conserved nutrient sensing proteins kinase that regulates development and metabolism in every eukaryotic cells. ...
  http://expandingmarketing.com/category/stem-cell-dedifferentiation/
*  Dedifferentiation of neoplastic cells in medullary thyroid carcinoma: Report of a case | SpringerLink
Dedifferentiation of neoplastic cells in medullary thyroid carcinoma: Report of a case. ... These cytological changes might represent dedifferentiation of the neoplastic cells or the anaplastic transformation of MTC. ... Nishiyama RH, Dunn EL, Thompson NW (1972) Anaplastic spindle-cell and giant-cell tumors of the thyroid gland. Cancer 30:113-127 ... Roediger WEW (1973) A comparative study of the normal human neonatal and the canine thyroid C cell. J Anat 115:255-276PubMed ...
  https://link.springer.com/article/10.1007/BF02482271
*  HGF Accelerates Wound Healing by Promoting the Dedifferentiation of Epidermal Cells through -Integrin/ILK Pathway
H. Li, X. Fu, L. Zhang, T. Sun, and J. Wang, "In vivo dedifferentiation of human epidermal cells," Cell Biology International, ... "Dedifferentiation derived cells exhibit phenotypic and functional characteristics of epidermal stem cells," Journal of Cellular ... HGF Accelerates Wound Healing by Promoting the Dedifferentiation of Epidermal Cells through -Integrin/ILK Pathway. Jin-Feng Li, ... P. H. Jones, S. Harper, and F. M. Watt, "Stem cell patterning and fate in human epidermis," Cell, vol. 80, no. 1, pp. 83-93, ...
  https://www.hindawi.com/journals/bmri/2013/470418/ref/
*  SOX17 Regulates Conversion of Human Fibroblasts into Endothelial Cells and Erythroblasts via De-Differentiation into CD34+...
Conclusions-De-differentiation of fibroblasts to intermediate CD34+ progenitors gives rise to endothelial cells and ... SOX17 Regulates Conversion of Human Fibroblasts into Endothelial Cells and Erythroblasts via De-Differentiation into CD34+ ... SOX17 Regulates Conversion of Human Fibroblasts into Endothelial Cells and Erythroblasts via De-Differentiation into CD34+ ... SOX17 Regulates Conversion of Human Fibroblasts into Endothelial Cells and Erythroblasts via De-Differentiation into CD34+ ...
  http://circ.ahajournals.org/content/early/2017/04/05/CIRCULATIONAHA.116.025722.1
*  Abstract 4376: Acquired cancer stem cell like features through Oct4 mediated dedifferentiation | Cancer Research
Abstract 4376: Acquired cancer stem cell like features through Oct4 mediated dedifferentiation. Suresh M.K Kumar, Shujing Liu, ... Abstract 4376: Acquired cancer stem cell like features through Oct4 mediated dedifferentiation ... of Oct4 gene or transmembrane delivery of Oct4 protein promoted dedifferentiation of melanoma cells to CSC-like cells. The ... Abstract 4376: Acquired cancer stem cell like features through Oct4 mediated dedifferentiation ...
  http://cancerres.aacrjournals.org/content/71/8_Supplement/4376
*  MicroRNAs modulate Schwann cell response to nerve injury by reinforcing transcriptional silencing of dedifferentiation-related...
MicroRNAs modulate Schwann cell response to nerve injury by reinforcing transcriptional silencing of dedifferentiation-related ... MicroRNAs Modulate Schwann Cell Response to Nerve Injury by Reinforcing Transcriptional Silencing of Dedifferentiation-Related ... MicroRNAs Modulate Schwann Cell Response to Nerve Injury by Reinforcing Transcriptional Silencing of Dedifferentiation-Related ... MicroRNAs Modulate Schwann Cell Response to Nerve Injury by Reinforcing Transcriptional Silencing of Dedifferentiation-Related ...
  https://www.ncbi.nlm.nih.gov/pubmed/22131398
*  In This Issue | Cancer Discovery
Melanoma Cell Dedifferentiation Induces Resistance to T-cell Therapy. *Antitumor Activity of NY-ESO-1c259 Autologous T Cells in ... Melanoma Cell Dedifferentiation Induces Resistance to T-cell Therapy. See article, p. 935 ... Further, coculturing F5 TCR transduced T cells with human melanoma cell lines was sufficient to induce their dedifferentiation ... Persistent NY-ESO-1c259 cells were largely functional central memory and stem cell memory T cells. ...
  http://cancerdiscovery.aacrjournals.org/content/8/8/899?rss=1
*  Our Basic Diabetes Research | Naomi Berrie Diabetes Center
Cell Dedifferentiation As A Mechanism Of Diabetic -Cell Failure. Cell 150: 1223-1234 PMC3445031 ... cells arise cell-autonomously from Foxo1-deficient cells. Following ablation by the-cell toxin, streptozotocin, gut Ins+ cells ... Though we can now routinely generate insulin-producing cells from stem cells, the use of such cells in cell replacement is a ... Pancreatic -cell dedifferentiation as mechanism of diabetic -cell failure. Diabetes is thought to arise through a decrease in ...
  http://nbdiabetes.org/research/our-basic-diabetes-research
*  北京大学医学部机构知识库(IR@PKUHSC): Reversine Enhances Generation of Progenitor-like Cells by Dedifferentiation of Annulus Fibrosus Cells
Saraiya, Mansi,et al."Reversine Enhances Generation of Progenitor-like Cells by Dedifferentiation of Annulus Fibrosus Cells". ... Reversine Enhances Generation of Progenitor-like Cells by Dedifferentiation of Annulus Fibrosus Cells[J]. TISSUE ENGINEERING ... Reversine Enhances Generation of Progenitor-like Cells by Dedifferentiation of Annulus Fibrosus Cells. ... Reversine Enhances Generation of Progenitor-like Cells by Dedifferentiation of Annulus Fibrosus Cells.TISSUE ENGINEERING PART A ...
  http://ir.bjmu.edu.cn/handle/400002259/67424
*  Dedifferentiation, redifferentiation and bundle formation of smooth muscle cells in tissue culture: the influence of cell...
Dedifferentiation, redifferentiation and bundle formation of smooth muscle cells in tissue culture: the influence of cell ... Dedifferentiation, redifferentiation and bundle formation of smooth muscle cells in tissue culture: the influence of cell ... Dedifferentiation, redifferentiation and bundle formation of smooth muscle cells in tissue culture: the influence of cell ... Dedifferentiation, redifferentiation and bundle formation of smooth muscle cells in tissue culture: the influence of cell ...
  http://dev.biologists.org/content/32/2/297
*  FEZF1 - Fez family zinc finger protein 1 - Homo sapiens (Human) - FEZF1 gene & protein
Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for ... Expression is required in OSN to cell-autonomously regulate OSN axon projections. ... cell dedifferentiation Source: Ensembl. *forebrain anterior/posterior pattern specification Source: Ensembl. *negative ... Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer ...
  https://www.uniprot.org/uniprot/A0PJY2
*  Academic Programs Faculty - Last Initial L - Wake Forest School of Medicine
Abortion, Habitual; Progesterone; Cell Dedifferentiation; Cell Lineage; Bone Marrow Cells Department: 336-713-7777 ... Nanotubes, Carbon; Cell Movement; Cell Proliferation; Breast Neoplasms; Cell Line, Tumor Academic: 336-713-8052. Department: ... Pneumonia, Viral; Drug Resistance, Viral; Oseltamivir; Influenza A Virus, H1N1 Subtype; Precursor T-Cell Lymphoblastic Leukemia ...
  http://www.wakehealth.edu/School/FacultySR.htm?st=L&li=L&ft=R
*  Staff Profile - Faculty of Medical Sciences - Newcastle University
Beta cell dedifferentiation: Evidence for ductal progenitors as a source of new beta cells?. In: Diabetes UK Professional ... An in vitro model of beta cell de-differentiation and potential alpha cell reprogramming. In: Diabetes UK Professional ... Limitation of glucotoxicity-induced beta-cell dedifferentiation and alpha-cell transition following Nkx6.1 overexpression. In: ... 01.12.07-31.05.08 North East Stem Cell Institute (£8,000) - Phenotypic characterisation of stem cell derived beta-cells prior ...
  http://www.ncl.ac.uk/medicalsciences/research/groups/profile/jimshaw.html
*  Second Messengers in Newt Limb Regeneration: cAMP and cGMP Levels and Distribution | SpringerLink
These increases were associated with cell cycling (mainly in blastemata), cell dedifferentiation and cell movements (mainly in ... Cyclic Nucleotide Tritiated Thymidine cGMP Level Distal Stump Cell Dedifferentiation These keywords were added by machine and ... An autoradiographic study using tritiated Thymidine to follow cell proliferation and migration, Develop. Biol., 3:26-59.PubMed ... Boynton, A.L., and Whitfield, J.F., 1983, The role of cyclic AMP cell proliferation: a critical assessment of the evidence, Adv ...
  https://link.springer.com/chapter/10.1007/978-1-4684-9057-2_9
*  Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell...
This p21-associated cell cycle arrest is associated both with significant inhibition of the phosphorylation of the ... The p21 protein is a negative regulator of mammalian cell cycle progression that functions both by inhibiting cyclin dependent ... Taken together, these studies demonstrate the important role of p21 in regulating Rb phosphorylation and cell cycle progression ... proliferating cell nuclear antigen (PCNA). In this report, we show that adenovirus-mediated over-expression of human p21 ...
  https://www.semanticscholar.org/paper/Adenovirus-mediated-over-expression-of-the-kinase-Chang-Barr/37361bfe1af5c61a7846b700486a3f24825c455d
*  Advancing Crop Transformation in the Era of Genome Editing | Plant Cell
2001). Two phases of chromatin decondensation during dedifferentiation of plant cells: distinction between competence for cell ... Your Name) has sent you a message from Plant Cell Message Body (Your Name) thought you would like to see the Plant Cell web ... Using an automated cell screen, every gene could be knocked out sequentially in crop cells for a massive functional analysis. ... Viral and cell free systems could also be instrumental for the introduction of molecules into plant cells to optimize the ...
  http://www.plantcell.org/content/28/7/1510
*  B cell acute lymphoblastic leukemia relapse following CD19 CAR immune-pressure via de-differentiation and lineage switch | NIH...
B cell acute lymphoblastic leukemia relapse following CD19 CAR immune-pressure via de-differentiation and lineage switch. ... Our data demonstrates plasticity of leukemic cells under antigen-specific immune pressure, with de-differentiation and lineage ... Later relapses had loss of all the B cell surface markers, along with down regulation of B cell transcripts (such as EBF1 and ... CD19 is a surface marker restricted to B cells and highly expressed on B cell ALL. CD19 has been targeted through genetically ...
  https://researchfestival.nih.gov/2015/posters/cell-acute-lymphoblastic-leukemia-relapse-following-cd19-car-immune
*  Genipin-Cross-Linked Chitosan Nerve Conduits Containing TNF-α Inhibitors for Peripheral Nerve Repair | SpringerLink
Schwann cell dedifferentiation-associated demyelination leads to exocytotic myelin clearance in inflammatory segmental ... Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves. J. Cell Biol. 210:153-168, 2015.CrossRef ... Signaling pathways regulating dose-dependent dual effects of TNF-alpha on primary cultured Schwann cells. Mol. Cell Biochem. ... Axon degeneration: make the Schwann cell great again. Neural Regen. Res. 12:518-524, 2017.CrossRefPubMedPubMedCentralGoogle ...
  https://link.springer.com/article/10.1007/s10439-018-2011-0
*  Plus it
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell 2012;150:1223-1234pmid:22980982. ... Promoting adipose cell recruitment in the subcutaneous adipose tissue rather than merely inflating the cells would be ... In fact, in some individuals we saw only 5-10% of cells undergoing differentiation while, in others ∼80% of the cells became ... Interestingly, when a clone of committed adipose precursor cells was isolated from the C3H10T1/2 cells, which readily underwent ...
  http://diabetes.diabetesjournals.org/content/62/9/2997
*  This study analyzed 42 strains collected between 2009C2012 from different hospitals | Targeting NRAS in Melanoma and Acute...
Stem Cell Dedifferentiation *Stem Cell Differentiation *Stem Cell Proliferation *Stem Cell Signaling ... Cell adhesion and motility are very dynamic processes that require the * Dendritic cells (DCs) play a essential function in ...
  http://scienceofgreathealth.com/this-study-analyzed-42-strains-collected-between-2009c2012-from-different-hospitals/
*  Millicurrent stimulation of human articular chondrocytes cultivated in a collagen type-I gel and of human osteochondral...
... of human osteoarthritic chondrocytes cultivated in a 3 D collagen gel and of osteochondral explants directly influences cell ... Osteochondral explants and cell-seeded gel samples were cultivated in-vitro for three weeks. Samples of the verum groups were ... although some cells showed signs of a partial morphological dedifferentiation (Fig. 2A). Proteoglycans were produced in both ... In all samples cells remained viable, as TUNEL staining revealed. Regardless of stimulation only few proliferating cells could ...
  https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-10-43