Carbonic anhydrase III, muscle specific - Wikipedia
CA3 carbonic anhydrase III, muscle specific". Sly WS, Hu PY (1995). "Human carbonic anhydrases and carbonic anhydrase ... Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encode carbonic ... Du AL, Ren HM, Lu CZ, Tu JL, Xu CF, Sun YA (Mar 2009). "Carbonic anhydrase III is insufficient in muscles of myasthenia gravis ... Liu C, Wei Y, Wang J, Pi L, Huang J, Wang P (Sep 2012). "Carbonic anhydrases III and IV autoantibodies in rheumatoid arthritis ...
![CA3 carbonic anhydrase 3 [Homo sapiens (human)] - Gene - NCBI](data:image/png;base64,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)
CA3 carbonic anhydrase 3 [Homo sapiens (human)] - Gene - NCBI
CA-III. HEL-S-167mP. carbonate dehydratase III. carbonic anhydrase III, muscle specific. carbonic anhydrase IIII. epididymis ... Carbonic anhydrase III is a new target of HIF1alpha in prostate cancer model. Title: Carbonic anhydrase III is a new target of ... Carbonic Anhydrase III / CA3 Antibody, Mouse MAb * Carbonic Anhydrase III / CA3 Antibody, Rabbit PAb, Antigen Affinity Purified ... alpha_CA_I_II_III_XIII; Carbonic anhydrase alpha, isozymes I, II, and III and XIII. Carbonic anhydrases (CAs) are zinc- ...
![RCSB PDB - 6I0L: Crystal structure of human carbonic anhydrase I in complex with the 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-...](data:image/png;base64,/9j/4AAQSkZJRgABAQAAAQABAAD/2wCEAAkGBwgHBgEIBwgKCgkLDRYPDQwMDRsUFRAWIB0iIiAdHx8kKDQsJCYxJx8fLT0tMTU3Ojo6Iys/RD84QzQ5OjcBCgoKDQwNGg8PGjclHyU3Kzc3Nzc3Nys3Nzc3Nzc3Nzc3Nzc3Nzc3Nys3NzcrKzc3Nzc3Kzc3Nzc3Nzc3Nzc3N//AABEIABAAEAMBIgACEQEDEQH/xAAWAAEBAQAAAAAAAAAAAAAAAAAGBAP/xAAmEAABBAECBAcAAAAAAAAAAAABAgMEEQUAIQcSEzEIFBZRcYGR/8QAFAEBAAAAAAAAAAAAAAAAAAAABf/EABoRAAICAwAAAAAAAAAAAAAAAAERAAIDEiH/2gAMAwEAAhEDEQA/AG6H0n10sp6jiAe4u1e/1RJ+NaM5XoSuFqfMEpUpNEK2UL320TZyU+G/4kI8nHTxIakl1h1ltRJ3rl7EEUSf3UbLuZmZThS0jGSwXHk85UypIAuzRqgNICgThRy22AXZ/9k=)
RCSB PDB - 6I0L: Crystal structure of human carbonic anhydrase I in complex with the 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-...
Crystal structure of human carbonic anhydrase I in complex with the 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(4- ... Carbonic anhydrase 1. A, B. 261. Homo sapiens. Mutation(s): 0 Gene Names: CA1. EC: 4.2.1.1 (PDB Primary Data), 4.2.1.69 ( ... Carbonic anhydrase inhibitors (CAIs) of the sulfonamide, sulfamate and coumarin classes bearing the phenylureido tail found in ... Carbonic anhydrase inhibitors (CAIs) of the sulfonamide, sulfamate and coumarin classes bearing the phenylureido tail found in ...
Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths.
... P. ... Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths / P. ... CA9 is a membrane-tethered, carbonic anhydrase (CA) enzyme, expressed mainly at the external surface of cells, that catalyzes ... CA9 is a membrane-tethered, carbonic anhydrase (CA) enzyme, expressed mainly at the external surface of cells, that catalyzes ...
CA2 carbonic anhydrase 2 [Homo sapiens (human)] - Gene - NCBI
alpha_CA_I_II_III_XIII; Carbonic anhydrase alpha, isozymes I, II, and III and XIII. Carbonic anhydrases (CAs) are zinc- ... carbonic anhydrase 2. Names. carbonate dehydratase II. carbonic anhydrase B. carbonic anhydrase C. carbonic anhydrase II. ... Carbonic Anhydrases II and IX in Non-ampullary Duodenal Adenomas and Adenocarcinoma. Title: Carbonic Anhydrases II and IX in ... alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze ...
Nutrients | Free Full-Text | Effects of Three-Month Administration of High-Saturated Fat Diet and High-Polyunsaturated Fat...
After three months of diets, liver proteins were resolved by two-dimensional gel electrophoresis (2DE) using 17 cm non-linear 3 ... Renner, S.W.; Walker, L.M.; Forsberg, L.J.; Sexton, J.Z.; Brenman, J.E. Carbonic anhydrase III (Car3) is not required for fatty ... Zimmerman, U.-J.P.; Wang, P.; Zhang, X.; Bogdanovich, S.; Forster, R.E. Anti-Oxidative Response of Carbonic Anhydrase III in ... Carbonic anhydrase 3. P16015/NP_031632.2. Ca3. 237. 1.3e-19. 81%. 18/81. 6.89/. 29,633. 0.97. 1.14. 1.33. (*). 1.18. 1.37. (**) ...
Synthesis of sulfonamide conjugates of Cu(ii), Ga(iii), In(iii), Re(v) and Zn(ii) complexes: carbonic anhydrase inhibition...
T1 - Synthesis of sulfonamide conjugates of Cu(ii), Ga(iii), In(iii), Re(v) and Zn(ii) complexes: carbonic anhydrase inhibition ... Synthesis of sulfonamide conjugates of Cu(ii), Ga(iii), In(iii), Re(v) and Zn(ii) complexes: carbonic anhydrase inhibition ... Synthesis of sulfonamide conjugates of Cu(ii), Ga(iii), In(iii), Re(v) and Zn(ii) complexes: carbonic anhydrase inhibition ... Synthesis of sulfonamide conjugates of Cu(ii), Ga(iii), In(iii), Re(v) and Zn(ii) complexes: carbonic anhydrase inhibition ...
Design, synthesis and molecular docking studies of novel benzimidazole-1,3,4-oxadiazole hybrids for their carbonic anhydrase...
... carbonic anhydrase inhibitory activities against two isoforms hCA I, hCA II, and antioxidant activity. The synthesized ... Carbonic anhydrase, Molecular Docking, Antioxidant, MICROWAVE-ASSISTED SYNTHESIS, ISOENZYMES HCA I, SCHIFF-BASES, DERIVATIVES, ... 4-oxadiazole hybrids for their carbonic anhydrase inhibitory and antioxidant effects ... Among all the compounds, 4a (1.826 mu M), 4d (1.502 mu M), and 4g (1.886 mu M) are the most active hybrids against carbonic hCA ...
Salts of 5-amino-2-sulfonamide-1,3,4-thiadiazole, a structural and analog of acetazolamide, show interesting carbonic anhydrase...
The p-toluensulfonate, the methylsulfonate, and the chlorhydrate monohydrate salts of Hats were evaluated as carbonic anhydrase ... show interesting carbonic anhydrase inhibitory properties, diuretic, and anticonvulsant action; Taylor & Francis Ltd; Journal ... show interesting carbonic anhydrase inhibitory properties, diuretic, and anticonvulsant action. .noexiste{ color: #000; } . ... The three Hats salts exhibited diuretic and anticonvulsant activities with little neurotoxicity. The human (h) isoforms hCA I, ...
Results for 'C2' | Abcam: antibodies, proteins, kits...
Blue light and CO2 signals converge to regulate light-induced stomatal opening | Nature Communications
Carbonic anhydrases βCA1 and βCA4 produce HCO3 − from CO2; the resulting HCO3 − activates RHC1, and the RHC1 inhibits HT1 ... Phosphorylation of these three proteins was determined by a mobility shift assay and phosphorylation of H+-ATPase was estimated ... Carbonic anhydrases are upstream regulators of CO2-controlled stomatal movements in guard cells. Nat. Cell Biol. 12, 87-93 ( ... Two carbonic anhydrases, βCA1 and βCA4, stimulate stomatal closure by converting CO2 to bicarbonate43. In contrast, HT1 kinase ...
1if8.1 | SWISS-MODEL Template Library
Carbonic Anhydrase II Complexed With (S)-N-(3-Indol-1-yl-2-methyl-propyl)-4-sulfamoyl-benzamide ... Carbonic Anhydrase II Complexed With (S)-N-(3-Indol-1-yl-2-methyl-propyl)-4-sulfamoyl-benzamide Coordinates. PDB Format Method ... SBS.3: 13 residues within 4Å:*. Chain A: H.93, H.95, H.118, V.120, F.129, V.133, V.141, L.196, T.197, T.198, P.200, W.207 ... 3 PLIP interactions:. 3 interactions with chain A. *. Metal complexes: A:H.93, A:H.95, A:H.118 ...
Long-Lasting GABA-Mediated Depolarization Evoked by High-Frequency Stimulation in Pyramidal Neurons of Rat Hippocampal Slice Is...
Effects of inhibitors of carbonic anhydrase on the GDPSP/C. A, Bath application of the impermeant carbonic anhydrase inhibitor ... The first three responses from two cells recorded with a sharp microelectrode or a whole-cell micropipette are shown. Note the ... carbonic anhydrase. There are functionally distinct kinds of carbonic anhydrases that play a crucial role in activity-induced ... Maren, 1977; Voipio et al., 1995). In nine slices examined, a full block of interstitial carbonic anhydrase with BA (10 μm ...
The Carbonic Anhydrase Domain Protein Nacrein is Expressed in the Epithelial Cells of the Mantle and Acts as a Negative...
The Carbonic Anhydrase Domain Protein Nacrein is Expressed in the Epithelial Cells of the Mantle and Acts as a Negative ... Hiroshi Miyamoto, Fumiko Miyoshi, and Jun Kohno "The Carbonic Anhydrase Domain Protein Nacrein is Expressed in the Epithelial ... Nacrein, which is composed of a carbonic anhydrase domain and a Gly-X-Asn repeat domain, is one of the organic matrix proteins ... Hiroshi Miyamoto, Fumiko Miyoshi, Jun Kohno "The Carbonic Anhydrase Domain Protein Nacrein is Expressed in the Epithelial Cells ...
Hypoventilation Syndromes Treatment & Management: Approach Considerations, Oxygen Therapy, Respiratory Stimulants
Acetazolamide is a diuretic that inhibits carbonic anhydrase, increases HCO3 excretion, and causes metabolic acidosis. The ... Re-evaluate patients in 1-3 months after initiating therapy, because some patients may improve and may not require long-term ... Infusion of sodium HCO3 is not indicated for chronic hypoventilation syndromes. ... syndrome with associated hypercapnia while receiving total daily doses of 60 mg of medroxyprogesterone in divided doses 2-3 ...
2hnc.1 | SWISS-MODEL Template Library
Crystal structure of the human carbonic anhydrase II in complex with the 5-amino-1,3,4-thiadiazole-2-sulfonamide inhibitor. ... Crystal structure of the human carbonic anhydrase II in complex with the 5-amino-1,3,4-thiadiazole-2-sulfonamide inhibitor. ... Menchise, V. et al., Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1,3,4-thiadiazole ... 1 x 1SA: 5-AMINO-1,3,4-THIADIAZOLE-2-SULFONAMIDE(Non-covalent). 1SA.2: 11 residues within 4Å:*. Chain A: H.93, H.95, H.118, V. ...
Safety monitoring of drug-induced muscle injury and rhabdomyolysis: a biomarker-guided approach for clinical practice and drug...
Characteristics of myoglobin, carbonic anhydrase III and the myoglobin/carbonic anhydrase III ratio in trauma, exercise, and ... These mainly include aldolase (Ald), lactate dehydrogenase (LDH), and carbonic anhydrase III (CA III). Ald is a glycolytic ... CA III is an isoform of the carbonic anhydrases and is mainly located in SKM (predominately in Type I, slow twitch fibers) [63 ... Harju, AK, Bootorabi, F, Kuuslahti, M, Supuran, CT, Parkkila, S. Carbonic anhydrase III: a neglected isozyme is stepping into ...
SCOPe 2.08: Structural Classification of Proteins - extended
Description: Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide. Class: lyase. Keywords: ... Compound: Carbonic anhydrase 9. Species: Homo sapiens [TaxId:9606]. Gene: CA9, G250, MN. Database cross-references and ... Compound: Carbonic anhydrase 9. Species: Homo sapiens [TaxId:9606]. Gene: CA9, G250, MN. Database cross-references and ... Compound: Carbonic anhydrase 9. Species: Homo sapiens [TaxId:9606]. Gene: CA9, G250, MN. Database cross-references and ...
Matassini Camilla | Scheda personale | Università degli Studi di Firenze | UniFI
... and three-tailed sugar and iminosugar decorated benzenesulfonamide carbonic anhydrase inhibitors. ORGANIC & BIOMOLECULAR ... "Glycomimetic based approach toward selective carbonic anhydrase inhibitors". ACS Med Chem Lett 2020, DOI: 10.1021/ ... Synthesis of Azasugar-Sulfonamide conjugates and their Evaluation as Inhibitors of Carbonic Anhydrases: the Azasugar Approach ... Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors. ACS MEDICINAL CHEMISTRY LETTERS, vol. 11, pp. 727- ...
IUCr) Acta Crystallographica Section D Volume 64, Part 10, October 2008
Three crystal structures of the γ-carbonic anhydrase enzyme from P. horikoshii were solved in space group F4132. The enzyme ... Observation of a calcium-binding site in the γ-class carbonic anhydrase from Pyrococcus horikoshii. ... X-ray crystal structures have been obtained and molecular-dynamics simulations have been carried out for three active-site ... Structures and molecular-dynamics studies of three active-site mutants of bovine pancreatic phospholipase A2. ...
Carbonic Anhydrase I Isoelectric focusing marker, pI 6.6 9001-03-0
Carbonic Anhydrase I from human erythrocytes has been used as a pI (isoelectric point) marker in two-dimensional gel ... Carbonic Anhydrase I from human erythrocytes is a protein which is used as a standard pI (isoelectric point) marker for ... Carbonic Anhydrase I from human erythrocytes has been used as a pI (isoelectric point) marker in two-dimensional gel ...
Neutrophils actively swell to potentiate rapid migration
2002Carbonic anhydrase II binds to and enhances activity of the Na+/H+ exchangerJ Biol Chem. 277:36085-36091 ... Three time points were taken to set a baseline, and then fMLP (Sigma) was added to a final concentration of 20 nM, and the ... Similarly, carbonic anhydrases have been implicated in enhancing NHE1 activity Li et al. (2006) and facilitating migration ... 2012Carbonic Anhydrase IX Interacts with Bicarbonate Transporters in Lamellipodia and Increases Cell Migration via Its ...
RCSB PDB - 2VVA: Human carbonic anhydrase in complex with CO2
CARBONIC ANHYDRASE 2. A [auth X]. 260. Homo sapiens. Mutation(s): 0 Gene Names: CA2. EC: 4.2.1.1 (PDB Primary Data), 4.2.1.69 ( ... Structural Study of X-Ray Induced Activation of Carbonic Anhydrase.. Sjoblom, B., Polentarutti, M., Djinovic-Carugo, K.. (2009 ... Carbonic anhydrase, a zinc metalloenzyme, catalyzes the reversible hydration of carbon dioxide to bicarbonate. It is involved ... More than 100 distinct human carbonic anhydrase II (HCAII) 3D structures have been generated in last 3 decades [Liljas A, et al ...
SCOPe 2.08: Domain d1xq0a : 1xq0 A
Superfamily b.74.1: Carbonic anhydrase [51069] (2 families) *. Family b.74.1.1: Carbonic anhydrase [51070] (2 proteins). ... PDB Compounds: (A:) carbonic anhydrase II. SCOPe Domain Sequences for d1xq0a_:. Sequence; same for both SEQRES and ATOM records ... Protein Carbonic anhydrase [51071] (10 species). *. Species Human (Homo sapiens), erythrocytes, isozyme II [TaxId:9606] [51073 ... PDB Description: Structure of human carbonic anhydrase II with 4-[(3-bromo-4-O-sulfamoylbenzyl)(4-cyanophenyl)amino]-4H-[1,2,4 ...
Significant molecular and systemic adaptations after repeated sprint training in hypoxia
Hypochloremic Alkalosis Medication: Electrolytes, Nonsteroidal Anti-inflammatory Drugs, Carbonic Anhydrase Inhibitors,...
Mutations in the chloride channel gene, CLCNKB, cause Bartters syndrome type III. Nat Genet. 1997 Oct. 17(2):171-8. [QxMD ... The major pharmacologic action of agents in this class is noncompetitive inhibition of the enzyme carbonic anhydrase. Carbonic ... Hydrochloric acid (HCl) and carbonic anhydrase inhibitors may be used in some acute situations. ... anhydrase is located at the luminal border of cells of the proximal tubule. Urine volume increases with enzyme inhibition ( ...
CAH8 HUMAN - Carbonic Anhydrase-related Protein 8, Human | ZINC Is Not Commercial - A database of commercially-available...
Carbonic Anhydrase II, Human. 2,967. 379. 112. 102. CAH3_HUMAN. P07451. CHEMBL2885. Carbonic Anhydrase III, Human. 76. 47. 33. ... Carbonic Anhydrase XIV, Human. 322. 95. 42. 48. CAH1_HUMAN. P00915. CHEMBL261. Carbonic Anhydrase I, Human. 2,197. 284. 79. 75 ... Carbonic Anhydrase VII, Human. 272. 116. 52. 56. CAH9_HUMAN. Q16790. CHEMBL3594. Carbonic Anhydrase IX, Human. 1,000. 180. 68. ... Carbonic Anhydrase XII, Human. 544. 146. 66. 65. CAH13_HUMAN. Q8N1Q1. CHEMBL3912. Carbonic Anhydrase XIII, Human. 85. 27. 16. ...
Rubisco condensate formation by CcmM in β-carboxysome biogenesis | Nature
... which contains a carbonic anhydrase-like domain8 followed by three Rubisco small subunit-like (SSUL) modules connected by ... carbonic anhydrase generates high concentrations of CO2 for carbon fixation by Rubisco6. The shell also prevents access to ... which lacks the carbonic anhydrase-like domain11. It has long been speculated that the SSUL modules interact with Rubisco by ... subunits-and carbonic anhydrase2-4. As HCO3− can diffuse through the proteinaceous carboxysome shell but CO2 cannot5, ...
Frontiers | Sarcopenia and Androgens: A Link between Pathology and Treatment
aged vastus lateralis reveals increased levels of carbonic anhydrase isoform 3 in senescent human skeletal muscle. Int J Mol ... Rodrigo Maass3 Manuel Estrada2*. *1Programa de Anatomía y Biología del Desarrollo, Facultad de Medicina, Instituto de Ciencias ... Biogerontology (2002) 3:265-70. doi:10.1023/A:1020189627325. Pubmed Abstract , Pubmed Full Text , CrossRef Full Text , Google ... 3. Rosenberg IH. Summary comments. Am J Clin Nutr (1989) 50(Suppl):1231S-3S. ...
Physical and functional interaction of carbonic anhydrases and NBCe1 Na+/HCO3 contransporter in the heart. - Physiological Mini...