Figures and data in Homeodomain-interacting protein kinase maintains neuronal homeostasis during normal Caenorhabditis elegans...
... each originating from discrete neuronal subtypes within the Caenorhabditis elegans nervous system to preserve neuronal health ... homeodomain-interacting protein kinase) functions as a key regulator of multiple proteostatic stress responses, ... Homeodomain-interacting protein kinase maintains neuronal homeostasis during normal Caenorhabditis elegans aging and ... Homeodomain-interacting protein kinase maintains neuronal homeostasis during normal Caenorhabditis elegans aging and ...
Function of Protein Kinase C-1 in memory in Caenorhabditis elegans Poster | Technology Networks
... elegans, we conditioned the nematodes to form an association between the odorant benzaldehyde and starvation. ... Function of Protein Kinase C-1 in memory in Caenorhabditis elegans. Poster Published: June 12, 2013 ... We found that wild-type C. elegans form food-odor associations and retain them for at least 12 hours. Results show that nj1 ... Assays that utilized their naïve attractive response were performed on N2 wild-type C. elegans and the pkc-1 mutant nj1, to ...
Cholesterol-Responsive Metabolic Proteins Are Required for Larval Development in Caenorhabditis elegans
Caffeine Induces the Stress Response and Up-Regulates Heat Shock Proteins in Caenorhabditis elegans. Mohammad Al-Amin, Ichiro ... Cholesterol-Responsive Metabolic Proteins Are Required for Larval Development in Caenorhabditis elegans. Ichiro Kawasaki, Myung ... Cholesterol-Responsive Metabolic Proteins Are Required for Larval Development in Caenorhabditis elegans. Ichiro Kawasaki, Myung ... Caenorhabditis elegans, a cholesterol auxotroph, showed defects in larval development upon cholesterol starvation (CS) in a ...
How glutamate transporter deletion influences behavior, longevity, and protein expression in Caenorhabditis elegans
How glutamate transporter deletion influences behavior, longevity, and protein expression in Caenorhabditis elegans Meeting ...
Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans - WRAP: Warwick...
2008) Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans. Aging Cell, Vol ... Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans ... Over-expression of the C. elegans glyoxalase-1 orthologue CeGly decreases MG modifications of mitochondrial proteins and ... Studies of mutations affecting lifespan in Caenorhabditis elegans show that mitochondrial generation of reactive oxygen species ...
Sel-12 - Wikipedia
The Caenorhabditis elegans sel-12 gene encodes a multi-pass transmembrane domain protein that is similar to human presenilin. ... a Caenorhabditis elegans S182 Alzheimers disease gene". Nature. 377 (6547): 351-354. Bibcode:1995Natur.377..351L. doi:10.1038/ ... sel-12 also plays a role in thermotaxis (the nematode worm prefers a certain temperature and moves accordingly). C. elegans ... Stefan Eimer (2003). "Analysis and suppression of mutant sel-12 in C. elegans". Ph.D. Thesis, Ludwig-Maximilians Universität, ...
The recycling endosome protein RAB-10 promotes autophagic flux and localization of the transmembrane protein ATG-9
Caenorhabditis elegans * Caenorhabditis elegans Proteins / metabolism* * Caenorhabditis elegans Proteins / physiology* * ... The recycling endosome protein RAB-10 promotes autophagic flux and localization of the transmembrane protein ATG-9 Autophagy. ... However, how endocytic proteins functionally intersect with autophagy is not clear. Mutations in the DAF-2/insulin-like IGF-1 ( ...
The landscape of RNA polymerase II transcription initiation in C. elegans reveals promoter and enhancer architectures
The initial 5 end of most protein-coding transcripts is removed by trans-splicing, and noncoding initiation sites have not ... RNA polymerase transcription initiation sites are largely unknown in Caenorhabditis elegans. ... RNA polymerase transcription initiation sites are largely unknown in Caenorhabditis elegans. The initial 5 end of most protein ... The landscape of RNA polymerase II transcription initiation in C. elegans reveals promoter and enhancer architectures Genome ...
Sec1p/Munc18 (SM) proteins and their role in regulating secretion in Saccharomyces cerevisiae and Caenorhabditis elegans a...
Sec1p/Munc18 (SM) proteins and their role in regulating secretion in Saccharomyces cerevisiae and Caenorhabditis elegans a ... Sec1p/Munc18 (SM) proteine und deren Rolle in der Sekretionsregulierung in Saccharomyces cerevisiae und Caenorhabditis elegans ... Keywords: ITC; Syntaxin; SNAREs; Membrane Fusion; Neuronal Secretion; Sec1/Munc18; Biochemitry; Protein-Protein Interactions ... Schlagwörter: ITC; Syntaxin; SNAREs; Membrane Fusion; Neuronal Secretion; Sec1/Munc18; Biochemitry; Protein-Protein ...
Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated...
Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated ... Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated ... Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated ... Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated ...
Interaction of structure-specific and promiscuous G-protein-coupled receptors mediates small-molecule signaling in...
JCI - Huntingtin in health and disease
Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA. 2000. 97:5750 ... Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron. Proc. Natl. Acad. Sci. USA. ... In HD, the protein with the expanded polyQ may not function as effectively as the wild-type protein, and this may put neurons ( ... In contrast, in control brains there was full-length protein in the total homogenate but no nuclear protein and few huntingtin ...
SGN Unigene - Show All Stored BLAST Hits - Sol Genomics Network
gi,7505775,pir,,T23603 hypothetical protein K11D2.3 - Caenorhabditis elegans. Match: gi,46229467,gb,EAK90285.1,. score: 406.8. ... gi,7506755,pir,,T33569 hypothetical protein R160.1 - Caenorhabditis elegans. Match: gi,48097876,ref,XP_391965.1,. score: 273.9 ... gi,7448830,pir,,T15189 hypothetical protein F55A12.7 - Caenorhabditis elegans. Match: gi,19112573,ref,NP_595781.1,. score: ... gi,1078839,pir,,B49837 clathrin-associated protein AP50 homolog CEAP - Caenorhabditis elegans gi,451886,gb,AAA27981.1.... ...
Structure and Function of PICK1 | Neurosignals | Karger Publishers
PICK1 is a peripheral membrane protein conserved from Caenorhabditis elegans to the human. It is expressed in many tissues with ... The PDZ domain of PICK1 binds to a large number of membrane proteins, especially proteins with C-terminal type II PDZ-binding ... PICK1, PDZ domain, BAR domain, Protein trafficking, AMPA receptor, Long-term potentiation, Long-term depression, Synaptic ... the unique structure of PICK1 enables it to couple membrane proteins to protein-trafficking machinery. ...
Mutations in Fibroblast Growth Factor Receptor 2 and Fibroblast Growth Factor Receptor 3 Genes Associated with Human Gastric...
... nematode egl-15 protein (Caenorhabditis elegans), g3877838; yeast Cdc 15p (Saccharomyces cerevisiae), g349757; human FGFR1 (flg ... B, in 386C (CRC), substitution of a highly conserved Glu (from C. elegans to man) by a Lys as a result of a missense mutation. ... B, in 386C (CRC), substitution of a highly conserved Glu (from C. elegans to man) by a Lys as a result of a missense mutation. ... For tumor suppressor proteins, highly conserved residues in human and mice have been instrumental in highlighting domains of ...
Amyloid by default | Nature Neuroscience
SMART: Pfam domain SBDS C
Caenorhabditis elegans hypothetical protein W06E11.4.. *Methanocaldococcus jannaschii (Methanococcus jannaschii) hypothetical ... This entry represents the C-terminal domain of proteins that are highly conserved in species ranging from archaea to ... A number of uncharacterised hydrophilic proteins of about 30kDa share regions of similarity. These include, ... proteins from both mouse and humans. Shwachman-Diamond syndrome is an autosomal recessive disorder with clinical features that ...
NYU Biology Faculty Directory
Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network.. Nat Methods (2009 Jan) ... Backbone 1H, 15N and 13C assignments for the 21 kDa Caenorhabditis elegans homologue of brain-specific protein.. J Biomol NMR ... A Caenorhabditis elegans genetic-interaction map wiggles into view.. J Biol (2008) PMC2323036 free full-text archive. Gunsalus ... A protein domain-based interactome network for C. elegans early embryogenesis.. Cell (2008 Aug 8) PMC2596478 free full-text ...
SMART: Pfam domain His Phos 2
Several Caenorhabditis elegans hypothetical proteins.. This is a PFAM domain. For full annotation and more information, please ... Acid phosphatases are a heterogeneous group of proteins that hydrolyse phosphate esters, optimally at low pH. The catalytic ... functions of these proteins include phytase, glucose-1-phosphatase and multiple inositol polyphosphate phosphatase. Fungal ...
Sol Genomics Network
CIPSM - Research Area F
... the Caenorhabditis elegans homolog of the French Canadian Leigh Syndrome protein LRPPRC (leucine-rich pentatricopeptide repeat ... and Cardiolipin-Induced Changes of Two Caenorhabditis elegans Cytochrome c Proteins. ... Recombinant expression of Caenorhabditis elegans CYC-2.1 and CYC-2.2 allowed for detailed characterization of their structural ... We present evidence that the Snail-related transcription factor CES-1 of Caenorhabditis elegans coordinates these processes in ...
Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange | Protocol (Translated to...
Repression of mesodermal fate by foxa, a key endoderm regulator of the sea urchin embryo | Development | The Company of...
Regulation of organogenesis by the Caenorhabditis elegans FoxA protein PHA-4. Science ... are required to distinguish the fates of equivalent blastomeres in the early Caenorhabditis elegans embryo. Development ... Orthologous genes have been isolated in many different species, including Drosophila (Weigel et al.,1989), C. elegans(Mango et ... Two Otx proteins generated from multiple transcripts of a single gene in Strongylocentrotus purpuratus. Dev. Biol. ...
Kindler Syndrome: Background, Pathophysiology, Epidemiology
Kindlin-1 is a human homolog of the Caenorhabditis elegans protein UNC-112, a membrane-associated structural/signaling protein ... Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes ... This gene encodes a 677-amino acid protein, kindlin-1, which is thought to play a regulatory role in inhibiting oversecretion ... Recurrent mutations in kindlin-1, a novel keratinocyte focal contact protein, in the autosomal recessive skin fragility and ...
Chemical synthesis | PLOS ONE
WikiGenes
The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway. Patterson, ... The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway.. Signals ... In Caenorhabditis elegans, defects in a TGF-beta-related pathway cause a reversible developmental arrest and metabolic shift at ... and associated Smad signal transduction proteins. daf-3 encodes a Smad protein that is most closely related to mammalian DPC4, ...
SCOPe 2.08: Domain d1tova : 1tov A
Protein Cytoskeleton-associated protein F53F4.3 [74926] (1 species). *. Species Nematode (Caenorhabditis elegans) [TaxId:6239] ... d1tova_ b.34.10.1 (A:) Cytoskeleton-associated protein F53F4.3 {Nematode (Caenorhabditis elegans) [TaxId: 6239]} ... PDB Description: Structural genomics of Caenorhabditis elegans: CAP-GLY domain of F53F4.3 ... PDB Compounds: (A:) Hypothetical protein F53F4.3 in chromosome V. SCOPe Domain Sequences for d1tova_:. Sequence; same for both ...
Metabolic Detoxication, Phase II | Harvard Catalyst Profiles | Harvard Catalyst
Genomic overview of protein kinases
Plowman, G.D., Sudarsanam, S., Bingham, J., Whyte, D., and Hunter, T. (1999). The protein kinases of Caenorhabditis elegans: a ... Myotonic dystrophy protein kinase. AGC. DMPK. ROCK. 1. Metazoans, Dictyostelium. let-502. Myotonic dystrophy protein kinase/Rho ... The C. elegans kinome is also marked by a dramatic expansion of a small number of kinase classes. C. elegans has almost twice ... Vowels, J.J., and Thomas, J.H. (1992). Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans. ...