Computational models based on hippocampal connectivity have proposed that CA3 is uniquely positioned as an autoassociative ... Ensemble dynamics of hippocampal regions CA3 and CA1 Neuron. 2004 Nov 18;44(4):581-4. doi: 10.1016/j.neuron.2004.11.003. ... Computational models based on hippocampal connectivity have proposed that CA3 is uniquely positioned as an autoassociative ... have examined the responses of CA3 and CA1 ensembles to alterations of environmental context in rats. The results provide ...

On the linkage between AMPA and NMDA receptor-mediated EPSPs in homosynaptic long-term depression in the hippocampal CA1 region ... On the linkage between AMPA and NMDA receptor-mediated EPSPs in homosynaptic long-term depression in the hippocampal CA1 region ... On the linkage between AMPA and NMDA receptor-mediated EPSPs in homosynaptic long-term depression in the hippocampal CA1 region ... On the linkage between AMPA and NMDA receptor-mediated EPSPs in homosynaptic long-term depression in the hippocampal CA1 region ...

Excitatory effects of low-level lead exposure on action potential firing of pyramidal neurons in CA1 region of rat hippocampal ... firing of pyramidal neurons in CA1 region of rat hippocampal slices and the pathway through which lead induced these effects ...

"CA1 Region, Hippocampal" by people in this website by year, and whether "CA1 Region, Hippocampal" was a major or minor topic of ... "CA1 Region, Hippocampal" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... CA1 Region, Hippocampal*CA1 Region, Hippocampal. *Hippocampal CA1 Region. *Region, Hippocampal CA1 ... Below are the most recent publications written about "CA1 Region, Hippocampal" by people in Profiles. ...

Cerebral Cortex - CA1 Region, Hippocampal PubMed MeSh Term *Overview. Overview. subject area of * A Behavioral Analysis of the ... Peripheral Immune Challenge and Aging Interact to Disrupt Theta-Burst Late-Phase Long-Term Potentiation in Hippocampal Area CA1 ... The eIF2α kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression. ...

1996) Hippocampal CA3 region predicts memory sequences: accounting for the phase precession of place cells. Learn Mem 3:279-287 ... Impact of hippocampal theta and beta activity on target areas. Our results suggest that the continuation of structured CA1 ... 8A,B). These numbers were lower than for hippocampal area CA1 in both frequency bands, as expected from a limited connection ... Reward Expectancy Strengthens CA1 Theta and Beta Band Synchronization and Hippocampal-Ventral Striatal Coupling. Carien S. ...

... of storage and recall of patterns in the CA1 region of the mammalian hippocampus. Patterns of PC activity are stored either by ... 1 . Cutsuridis V, Cobb S, Graham BP (2010) Encoding and retrieval in a model of the hippocampal CA1 microcircuit. Hippocampus ... Active dendrites and spike propagation in a hippocampal interneuron (Saraga et al 2003). CA1 network model for place cell ... CA1 network model: interneuron contributions to epileptic deficits (Shuman et al 2019). CA1 pyramidal neuron: as a 2-layer NN ...

... of storage and recall of patterns in the CA1 region of the mammalian hippocampus. Patterns of PC activity are stored either by ... 1 . Cutsuridis V, Cobb S, Graham BP (2010) Encoding and retrieval in a model of the hippocampal CA1 microcircuit. Hippocampus ... Active dendrites and spike propagation in a hippocampal interneuron (Saraga et al 2003). CA1 network model for place cell ... CA1 network model: interneuron contributions to epileptic deficits (Shuman et al 2019). CA1 pyramidal neuron: as a 2-layer NN ...

Antagonism of group III metabotropic glutamate receptors results in impairment of LTD but not LTP in the hippocampal CA1 region ... In the CA1 region antagonism of group III mGluRs prevents LTD in vivo. Effects on LTP in vivo are as yet unknown. We ... Application of CPPG prevented LTD, but not LTP, in the CA1 region. These data suggest that activation of group III mGluRs is ... Recently it has emerged that hippocampal long-term depression (LTD) may play an important role in the acquisition and storage ...

Layer II projects primarily to dentate gyrus and hippocampal region CA3; layer III projects primarily to hippocampal region CA1 ... Alterations in the neural activity across the brain region results in an observed "traveling wave" phenomena across the MEC ... An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. ... It is usually divided into medial and lateral regions with three bands with distinct properties and connectivity running ...

In male rats, TRAP significantly increased hippocampal neurogenesis, while in females, TRAP increased granule cell layer width ... As indicated by immunohistochemical analyses, TRAP significantly increased microglial infiltration in the CA1 hippocampus, but ... 2). Sex did not significantly affect the outcome in any hippocampal region (CA1: F (1,19) = 1.717, p = 0.514; DG: F (1,19) = ... 2e, Students t test, p = 0.058). Within the CA1 and CA3, TRAP had no significant effect on GFAP (Fig. 2d, CA1 p = 0.690; CA3 p ...

CA1 (−4 AP; ±2.40 ML and −2.5 DV). GFP and PKD1-Ca lentiviral particles were injected in CA1 hippocampal regions at the right ... a Adult male Wistar rats were stereotaxically grafted in the hippocampal CA1 region with GFP (right hemisphere) or PKD-Ca (left ... Representative confocal microscopy images of the hippocampal CA1 region are shown (n = 3 animals per conditions). d ... hippocampal CA1 and CA3 regions) in the rat and mouse brain3. ... A total volume of 2.5 μl per CA1 region of each viral ...

... neuronal injury and apoptosis in rat hippocampal tissues. The effects caused by propofol were attenuated by esketamine. ... The morphological changes of neurons in the hippocampal CA1, CA3 and dentate gyrus (DG) regions were observed under a ... a) Representative images of HE staining for detecting the morphological changes of neurons in rat hippocampal CA1 region. The ... HE staining was used for histopathological observation of the rat hippocampi in CA1, CA3 and DG regions. Results show that ...

Electrical coupling is also known to be important in the development of hippocampal and neocortical principal cell networks. We ... Spontaneous sharp-wave ripple in CA1 region of mouse middle hippocampal slice. Pyramidal cell somatic intracellular recording ... Andrew, R.D., Taylor, C.P., Snow, R.W., and Dudek, F.E. (1982). Coupling in rat hippocampal slices: Dye transfer between CA1 ... In this regard, we note that Cx45 expression in the hippocampal CA1 pyramidal cells has been detected by some (Weickert et al ...

The temporal lobe is the most epileptogenic region of the brain. In fact, 90% of patients with temporal interictal epileptiform ... Hippocampal sclerosis involves hippocampal cell loss in the CA1 and CA3 regions and the dentate hilus. The CA2 region is ... Hippocampal sclerosis. Approximately two thirds of patients with temporal lobe epilepsy treated surgically have hippocampal ... The temporal lobe is the most epileptogenic region of the brain. In fact, 90% of patients with temporal interictal epileptiform ...

Hippocampal full-length dystrophin (Dp427) levels are upregulated in human TLE, but not in AK rats, possibly indicating a ... In these regions it colocalized with GFAP, suggesting expression in astrocytes such as Bergmann glia (BG) and velate ... In addition, hippocampal dystrophin levels were estimated by Western blot analysis in biopsies from TLE patients, post-mortem ... In addition, hippocampal dystrophin levels were estimated by Western blot analysis in biopsies from TLE patients, post-mortem ...

... particularly the neurons in the hippocampal CA1 region. Apoptos ... particularly the neurons in the hippocampal CA1 region. ... transferase-mediated dUTP nick-end labeling positive cells and expression of Bcl-2 and Bax in the hippocampal CA1 region were ... the expression of anti-apoptotic gene Bcl-2 while suppressed the expression of pro-apoptotic gene Bax in hippocampal CA1 region ... Danielisova V, Gottlieb M, Nemethova M et al (2009) Bradykinin postconditioning protects pyramidal CA1 neurons against delayed ...

We used a modified Golgi-Cox staining method to determine the progressive changes in dendritic structure of hippocampal CA1 ... We used a modified Golgi-Cox staining method to determine the progressive changes in dendritic structure of hippocampal CA1 ... The hippocampal CA1 region is a major output target of the entorhinal cortex, which also processes inputs from multiple ... Hippocampal CA1 pyramidal neurons for tracing were selected from sections between bregma ~−1.1 and −2.6 mm. A mouse brain atlas ...

After behavioral tests were completed, serum, feces, and hippocampal tissue of rats were collected. RESULTS:The results showed ... Hippocampal CA1 region sections were deparaffinized and treated with EDTA antigen repair buffer (pH 8.0). Antibodies used were ... Figure 6. (A) Immunofluorescence confocal microscopy imaging hippocampus CA1 regions, magnification ×200. (B) Expression of ... Figure 6. (A) Immunofluorescence confocal microscopy imaging hippocampus CA1 regions, magnification ×200. (B) Expression of ...

The CA1 region of the brain is involved in learning, cognition, and memory; the neurons in this area are especially vulnerable ... Loss of hippocampal CA1 neurons is a cause of memory impairment in cognitive loss disorders. ... The rats also experienced memory deficits and significant decreases in hippocampal CA1 neurons, which are necessary for the ... In rats with NMN supplementation, both the volume and number of hippocampal CA1 neurons were increased significantly, thereby ...

Seabrook GR, Easter A, Dawson GR, and Bowery BJ (1997) Modulation of long-term potentiation in CA1 region of mouse hippocampal ... α5IA enhances LTP but has no effect on paroxysmal discharges recorded in the CA1 region of hippocampal brain slices. A, LTP ... mice and was specific to the CA1 region of the hippocampus, which is consistent with the distribution of the GABAA α5 subunit- ... in the stratum radiatum of the CA1 region were recorded using glass microelectrodes filled with 2 M NaCl. The signals were ...

... in the CA1 region in rats, indicating better hippocampal function [58]. However, few data are available on the effects of a low ... Identifying the mechanisms by which high KYNA levels in the hippocampal area may contribute to the deterioration of cognition ... activation of nAChRs and NMDA receptors contributes to the excitability of CA1 stratum radiatum interneurons in rat hippocampal ... Stone, T.W. Kynurenic acid blocks nicotinic synaptic transmission to hippocampal interneurons in young rats. Eur. J. Nneurosci. ...

... capacity of area CA1 is the greater sensitivity of its neurons to the external aggressions to which this hippocampal region is ... in CA1, CA3 and dentate gyrus regions. The results show a significant increase of CO activity in all of the regions studied in ... A total of 4 sections per animal and hippocampal region studied were used. ... this is the first time this technique has been used to determine oxidative metabolism of these hippocampal areas (CA1, CA3 and ...

The second project was an extracellular electrophysiological study of CA1 pyramidal cell region in the slice. A paired-pulse ... The second project was an extracellular electrophysiological study of CA1 pyramidal cell region in the slice. A paired-pulse ... Williamson, Robert (1991) An electrophysiological study of rat hippocampal function using the in vitro slice preparation. ... In the first, a method was developed for acutely isolating hippocampal pyramidal cells from the adult rat. This was designed to ...

The brain was cut into three coronal sections to observe the structure of hippocampal CA1, CA3 and DG regions. After dewaxing, ... NMN treatment alleviated microglial and astrocyte activation and inhibited inflammatory response in hippocampal CA1 at 8 days ... Scale bar: 40 nm (n =3 per group). B) Quantitative analysis of NEUN fluorescence intensity in CA1 region (n =3 per group). C) ... A) Representative fluorescence images for staining of GFAP in CA1 region. Scale bar = 40 μm (n =3 per group). B) Representative ...

In COX-2 knockout mice, EP2 immunoreactivity was significantly decreased in the hippocampal CA1 region (P=0.000165) and dentate ... region. Activity levels of Malondialdehyde (MDA) and superoxide dismutase (SOD) were measured in the hippocampal tissue. ... This study aimed to evaluate the effects of TQ on spatial memory and hippocampal long-term potentiation (LTP) in rats with ... Data showed that the hippocampal content of MDA was increased while SOD activities were decreased in TAA-induced HE. TQ ...

Allan, Jon (2018) Modelling the effects of serotonin on the hippocampal CA1 region during navigation. PhD thesis, University of ...

The highest levels are in neurons of entorhinal cortex layer II, alongside hippocampal neurons at the CA1/subiculum border. ... but levels vary greatly between brain regions. The highest levels are in neurons of entorhinal cortex layer II, alongside ... hippocampal neurons at the CA1/subiculum border. Concerning entorhinal cortex layer II, we find similarly high levels of iAβ42 ... but levels vary greatly between brain regions. ...

DPCPX-resistant hypoxic synaptic depression in the CA1 region of hippocampal slices: possible role of intracellular ...

"Postsynaptic cAMP Pathway Gates Early LTP in Hippocampal CA1 Region". *287. Genieser H.-G., Proc. 9. Int. Conf. Second Mess. & ... "Forskolin-induced LTP in the CA1 Hippocampal Region is NMDA Receptor Dependent" ... USA, 92, 2446 - 2450 (1995), "D1/D5 Receptor Agonists Induce a Protein Synthesis-dependent Late Potentiation in the CA1 Region ... London, 545, 837 - 853 (2002), "Regulation of Cl--HCO3-Exchangers by cAMP-dependent Protein Kinase in Adult Rat Hippocampal CA1 ...