Schmidt & Clark Announces Multiple Lawsuits Filed Over Recalled Contact Lens Solution | Schmidt & Clark, LLP
The solution will reportedly use the preservative polyhexamethylene biguanide, which is the same disinfectant used in the ...https://www.schmidtandclark.com/schmidt-clark-announces-multiple-lawsuits-filed-over-recalled-contact-lens-solution
Browse Products Containing: POLYAMINOPROPYL BIGUANIDE || Skin Deep® Cosmetics Database | EWG
Products containing POLYAMINOPROPYL BIGUANIDE made by company: Destiny Boutique There are no products in the database that ...http://www.ewg.org/skindeep/browse.php?comp_id=2507&ingred06=704962&atatime=100&containing=704962&showmore=products&atatime=10
Browse Products Containing: POLYAMINIOPROPYL BIGUANIDE || Skin Deep® Cosmetics Database | EWG
Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Before a company can use EWG VERIFIEDTM on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. Learn more , Legal Disclaimer ...http://www.ewg.org/skindeep/browse.php?brand_id=4102&ingred06=861756
Patent WO2000035500A1 - Contact lens cleaner comprising biguanide and poloxamine - Google Patents
The present invention is directed to a biguanide-containing disinfecting solution containing a particular type of poloxamine ... for stabilizing a polymeric biguanide. The poloxamine surfactant comprises at least about 90 weight percent of poly(oxyethylene ... A polymeric biguanide can optionally be combined with a non-polymeric biguanide. Representative non-polymeric biguanides are ... Representative polymeric biguanides include hexamethylene biguanide (PHMB). Preferred polymeric biguanides, and water-soluble ...http://www.google.co.uk/patents/WO2000035500A1?cl=en
Patent US6936640 - Biguanide/quaternary ammonium containing copolymeric biocides and use ... - Google Patents
The biguanide/quaternary ammonium compounds are useful in the preservation of pharmaceutical compositions, particularly ... Biguanide/quaternary ammonium compounds and the use of same as antimicrobial agents in pharmaceutical compositions are ... The preferred biocides include: polyhexamethylene biguanide polymers ("PHMB"), polyquaternium-1, and the amino biguanides ... Biguanide group-containing polyallylamine and method of producing same. US5629385. 23 Nov 1994. 13 May 1997. Betzdearborn Inc. ...http://www.google.co.uk/patents/US6936640
1-(2,4-Xylyl)biguanide | C10H15N5 - PubChem
... biguanide , C10H15N5 , CID 20879 - structure, chemical names, physical and chemical properties, classification, patents, ...https://pubchem.ncbi.nlm.nih.gov/compound/20879
Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides
Remarkably, the biguanide sensitivity of cancer cells with mtDNA mutations was reversed by ectopic expression of yeast NDI1, a ... These defects predict sensitivity to biguanides, anti-diabetic drugs that inhibit OXPHOS3,4, when cancer cells are grown in low ... "Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides." Nature 508 (7494): 108-112. doi: ...https://dash.harvard.edu/handle/1/13347592
The American Journal of Tropical Medicine and Hygiene | Antimalarial Activity and Metabolism of Biguanides
Antimalarial Activity and Metabolism of Biguanides I. Metabolism of Chlorguanide and Chlorguanide Triazine in Rhesus Monkeys ...http://www.ajtmh.org/content/journals/10.4269/ajtmh.1961.10.694
Leisure Time Free Biguanide-Based Spa Sanitizer - Hot Tub Works
Leisure Time Free is a chlorine-free and bromine-free spa biguanide natural sanitizer free of odors. Shop a complete line of ... Leisure Time Free Biguanide-Based Sanitizer 16 fl. oz.. Our Price: $17.99. Sale Price: $14.39. Qty: Add to Cart. Item Added ... Leisure Time Free Biguanide-Based Sanitizer 16 fl. oz. - 2 Pack. Our Price: $26.05. Sale Price: $20.84. Qty: Add to Cart. Item ... Leisure Time Free Biguanide-Based Sanitizer 16 fl. oz. - 4 Pack. Our Price: $49.36. Sale Price: $39.49. Qty: Add to Cart. Item ...http://www.hottubworks.com/part-LT45500-item-hottub-sanitizer.php
Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria | Biochemical Journal
Effects of biguanides on F1F0-ATPase. The effects of biguanides on ATP hydrolysis by F1FO-ATPase were tested in SMPs by using a ... Thus we identify biguanides as a new class of complex I and ATP synthase inhibitor. By comparing biguanide effects on isolated ... Biguanide uptake into cells and mitochondria. Comparison of typical blood serum levels for the biguanides with their complex I ... Biguanides inhibit ubiquinone reduction, but not competitively. To narrow down the location at which biguanides bind to complex ...http://www.biochemj.org/content/462/3/475
1-(2,6-diethyl-phenyl)-biguanide | C12H19N5 - PubChem
... biguanide , C12H19N5 , CID 548295 - structure, chemical names, physical and chemical properties, classification, patents, ...https://pubchem.ncbi.nlm.nih.gov/compound/548295
Pioglitazone Tablets Special Drug Use Surveillance 'Combined Use of Biguanides / Long-term Treatment' - Full Text View -...
Patients who discontinued biguanides and switched to Actos Tablets treatment.. *Patients who received additional biguanides ... Pioglitazone Tablets Special Drug Use Surveillance 'Combined Use of Biguanides / Long-term Treatment'. The safety and ... Patients with type 2 diabetes mellitus who responded inadequately to treatment with biguanides in addition to diet therapy and ... To investigate the safety and efficacy of long-term treatment with pioglitazone (Actos tablets) in combination with biguanides ...https://www.clinicaltrials.gov/ct2/show/study/NCT02003014?term=237-017&rank=1
Alogliptin Tablets Special Drug Use Surveillance Type 2 Diabetes Mellitus: Combination Therapy With Biguanides - Tabular View -...
... once daily for up to 12 months along with biguanide or without biguanide within 3 months from the start of administration of ... and biguanides in participants with type 2 diabetes mellitus who responded inadequately to treatment with biguanides in ... Alogliptin Tablets Special Drug Use Surveillance Type 2 Diabetes Mellitus: Combination Therapy With Biguanides. The safety and ... The efficacy analysis was planned to be assessed in the total alogliptin arm irrespective of the biguanide treatment. ...https://clinicaltrials.gov/ct2/show/record/NCT01964976?show_rss=Y&sel_rss=mod14
US20100082097A1 - Article Containing Segregated Biguanide and Lewis Acid - Google Patents
A medical device includes a first region having a biguanide or a pharmaceutically acceptable salt thereof and a second region ... In addition, the biguanide may include a combination of two or more biguanides. The Lewis acid may include any suitable Lewis ... The biguanide may include any suitable agent such as chlorhexidine, alexidine, polyhexamethyl biguanide (PHMB), or the like or ... wherein the biguanide includes a mixture of a plurality of biguanide agents. ...https://patents.google.com/patent/US20100082097A1/en
Poly (hexamethylene biguanide) hydrochloride (CAS 32289-58-0) Market Research Report 2017
... hexamethylene biguanide) hydrochloride, examines its uses, production methods, patents. Poly (hexamethylene biguanide) ... 7. POLY (HEXAMETHYLENE BIGUANIDE) HYDROCHLORIDE END-USE SECTOR 7.1. Poly (hexamethylene biguanide) hydrochloride market by ... Poly (hexamethylene biguanide) hydrochloride market forecast. 6. POLY (HEXAMETHYLENE BIGUANIDE) HYDROCHLORIDE MARKET PRICES. ... Poly (hexamethylene biguanide) hydrochloride prices in Asia 6.3. Poly (hexamethylene biguanide) hydrochloride prices in North ...https://marketpublishers.com/report/industry/chemicals_petrochemicals/poly_hexamethylene_biguanide_hydrochloride_32289-58-0_market_research_report.html
Biguanide - Wikipedia
... and it is the principal biguanide drug used in pharmacotherapy worldwide. Biguanides do not affect the output of insulin, ... Biguanides also tend to make the cells of the body more willing to absorb glucose already present in the blood stream, and ... Biguanide (/baɪˈɡwɒnaɪd/) is the organic compound with the formula HN(C(NH)NH2)2. It is a colorless solid that dissolves in ... Biguanides were reintroduced into Type 2 diabetes treatment in the late 1950s. Initially phenformin was widely used, but its ...https://en.wikipedia.org/wiki/Biguanide
Alogliptin Tablets Special Drug Use Surveillance Type 2 Diabetes Mellitus: Combination Therapy With Biguanides - Full Text View...
... once daily for up to 12 months along with biguanide or without biguanide within 3 months from the start of administration of ... and biguanides in participants with type 2 diabetes mellitus who responded inadequately to treatment with biguanides in ... Biguanides. Hypoglycemic Agents. Physiological Effects of Drugs. Incretins. Hormones. Hormones, Hormone Substitutes, and ... Alogliptin Tablets Special Drug Use Surveillance Type 2 Diabetes Mellitus: Combination Therapy With Biguanides. This study has ...https://clinicaltrials.gov/ct2/show/NCT01964976?term=121-014&rank=1
Insta-TEST Biguanide, Alkalinity, pH, Total Hardness Test Strips - Pool and Spa - LaMotte
The one-dip Biguanide test strip measures Biguanide (0-80 ppm), Alkalinity (0-240 ppm), pH (6.2-9.0) and Total Hardness (0-800 ... Insta-TEST Biguanide, Alkalinity, pH, Total Hardness Test Strips. Order Code: 2938. ...http://www.lamotte.com/en/pool-spa/insta-test/2938.html
Polyaminopropyl biguanide - Wikipedia
Polyaminopropyl biguanide (PAPB) is a disinfectant and a preservative used for disinfection on skin and in cleaning solutions ... Gerit D. Mulder, Joseph P. Cavorsi and Daniel K. Lee (2007). "Polyhexamethylene Biguanide (PHMB): An Addendum to Current ... 2006). "The response of Escherichia coli to exposure to the biocide polyhexamethylene biguanide". Microbiology. 152 (4): 989- ... It is a polymer or oligomer where biguanide functional groups are connected by hexyl hydrocarbon chains, with varying chain ...https://en.wikipedia.org/wiki/Polyaminopropyl_biguanide
Energy balance at the organism and cellular level: effects of biguanides | Springer for Research & Development
... justifying study of combinations of each of these with biguanides. The separate hypothesis that biguanides can directly ... For example, there is evidence that tumours using glutamine as a carbon source are relatively sensitive to biguanides, that ... Recent work is identifying contexts where 'direct' actions of biguanides as inhibitors of OXPHOS may be of particular ... Therefore, studies of maximally tolerated doses of biguanides with more favourable pharmacokinetic properties than metformin ...https://rd.springer.com/article/10.1186/2049-3002-2-S1-O26
Polyhexamethylene Biguanide Increases the Regression Rate of Human Papillomavirus (HPV) Infection - No Study Results Posted -...
Polyhexamethylene Biguanide Increases the Regression Rate of Human Papillomavirus (HPV) Infection. The safety and scientific ... A new non-invasive approach based on polyhexamethylene biguanide increases the regression rate of HPV infection. BMC Clin ...https://clinicaltrials.gov/ct2/show/results/NCT01571141
Is Polyhexamethylene Biguanide (PHMB) an Effective Disinfectant for Adenovirus? | IOVS | ARVO Journals
Is Polyhexamethylene Biguanide (PHMB) an Effective Disinfectant for Adenovirus? Eric G. Romanowski; Kathleen A. Yates; ... Is Polyhexamethylene Biguanide (PHMB) an Effective Disinfectant for Adenovirus? You will receive an email whenever this article ... Purpose: : Polyhexamethylene biguanide (PHMB) is a disinfectant used in swimming pools, hot tubs, and contact lens solutions. ... Is Polyhexamethylene Biguanide (PHMB) an Effective Disinfectant for Adenovirus?. Invest. Ophthalmol. Vis. Sci. 2011;52(14):5857 ...https://iovs.arvojournals.org/article.aspx?articleid=2358308
U.K. prospective diabetes study. II. Reduction in HbA1c with basal insulin supplement, sulfonylurea, or biguanide therapy in...
Reduction in HbA1c with basal insulin supplement, sulfonylurea, or biguanide therapy in maturity-onset diabetes. A multicenter ...https://www.ncbi.nlm.nih.gov/pubmed/2862087
WO1997000076A1 - Compositions contenant des sels de poly(hexamethylene biguanide) et leurs utilisations - Google...
Utilisations de sels de poly(héxaméthylène biguanide), en particulier le sel d'hydrochlorure, dans la fabrication de ... hexamethylene biguanide. use. Prior art date. 1995-06-16. Application number. PCT/GB1996/001457. Other languages. English (en) ... Treatment of dandruff with biguanides JPS63183502A (en) * 1986-09-04. 1988-07-28. Ueno Seiyaku Oyo Kenkyusho:Kk. Virus ... Treatment of dandruff with biguanides JPS63183502A (en) * 1986-09-04. 1988-07-28. Ueno Seiyaku Oyo Kenkyusho:Kk. Virus ...https://patents.google.com/patent/WO1997000076A1/fr
Energy metabolism determines the sensitivity of human hepatocellular carcinoma cells to mitochondrial inhibitors and biguanide...
Biguanide drugs which inhibit mitochondrial complex I and repress mTOR signaling are clinically used to treat type 2 diabetes ... However, whether alteration of energy metabolism is involved in regulating the sensitivity of HCC to biguanide drugs is still ... In the present study, we treated four HCC cell lines with mitochondrial inhibitors (rotenone and oligomycin) and biguanide ... Enhancing the mitochondrial oxidative metabolism in combination with biguanide drugs may be a therapeutic strategy for HCC. ...https://www.sigmaaldrich.com/catalog/papers/26133123