B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B and CD257 among other names, ... "Elevated B cell-activating factor of the tumour necrosis factor family in coeliac disease". Scandinavian Journal of ... B-Cell+Activating+Factor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human DTL genome location and ... Lied GA, Berstad A (January 2011). "Functional and clinical aspects of the B-cell-activating factor (BAFF): a narrative review ...

What is the connection between B-cell activating factor and food hypersensitivity? ... B cell-activating factor is mainly produced and secreted not only by myeloid cells (macrophages, monocytes and dendritic cells ... B cell-activating factor (BAFF) is a member of the tumour necrosis factor (TNF) superfamily (TNFSF13B) and an important ... Results B cell-activating factor levels in serum and gut lavage fluid were significantly higher in patients than in controls (P ...

... factor Xa binds to human umbilical vein endothelial cells through the recognition of a protein called effector cell protease ... Factor Xa activates endothelial cells by a receptor cascade between EPR-1 and PAR-2 Arterioscler Thromb Vasc Biol. 2000 Nov;20( ... factor Xa binds to human umbilical vein endothelial cells through the recognition of a protein called effector cell protease ... signaling response induced by factor Xa. Conversely, pretreatment of endothelial cells with factor Xa blocked the PAR-2- ...

B cell activating factor (BAFF) is a ligand belonging to the tumor necrosis factor family and has an important role in B cells ... B cell activating factor gene polymorphisms in patients with risk of idiopathic thrombocytopenic purpura Samah M Abdel-Hamid 1 ... B cell activating factor gene polymorphisms in patients with risk of idiopathic thrombocytopenic purpura Samah M Abdel-Hamid et ... Significance of B cell activating factor of TNF family promoter polymorphisms in patients with immune thrombocytopenic purpura ...

We have developed a novel approach using short-activating RNA oligonucleotides to differentiate adult human CD34(+) cells into ... We provide a new approach using short-activating RNA in developing insulin producing surrogate cells for treating diabetes. ... fluorescence-activated cell sorting analysis, western blotting, and immunofluorescence staining. ... The differentiated cells appropriately processed C-peptide and insulin in response to increasing glucose stimulation as shown ...

Peroxisome proliferator-activated receptor α (PPARα) is thought to be involved in several different diseases, toxic responses, ... Tumour necrosis factor α (TNFα): role in suppression of apoptosis by the peroxisome proliferator nafenopin. Cell Mol Biol ( ... Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications ... Another area of active investigation has been whether PPARα agonists activate nonparenchymal liver cells such as Kupffer cells ...

These mutations lead to increased growth factor signaling and confer susceptibility to the inhibitor. Screening fo … ... A subgroup of patients with non-small-cell lung cancer have specific mutations in the EGFR gene, which correlate with clinical ... Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to ... Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to ...

We demonstrated that the transcription factor E2F1 accelerated cell proliferation and stemness in HCC by activating GINS1 ... Transcription Factor E2F1 Enhances Hepatocellular Carcinoma Cell Proliferation and Stemnes Transcription Factor E2F1 Enhances ... E2F transcription factor 1 (E2F1) was predicted as the upstream transcription factor of GINS1, and the binding relation between ... Afterward, the proliferative capacity and stemness of HCC tumor cells were determined through colony formation, cell counting ...

... Academic Article * ... It has been shown that AQP2 expression is regulated by the calcineurin/nuclear factor of activated T cells (NFATc). Nitric ... Cells were incubated with classic activators and inhibitors of NFATc and the NO pathway.Our results demonstrate that both Ca(2+ ... AQP2 promoter luciferase reporter- and NFAT luciferase reporter-transfected MDCK cells were used to determine AQP2 promoter ...

This study suggests that iodine directly promotes ferroptosis in activated B cells and attenuates GC reactions, leading to the ... In vitro treatment of activated B cells with potassium iodide induced ferroptosis by increasing intracellular reactive oxygen ... Accordingly, LBI diets increased ROS levels in GC B cells of the draining lymph nodes. ... Mascanfroni, I. D. et al. Nuclear factor (NF)-κB-dependent thyroid hormone receptor β1 expression controls dendritic cell ...

... mutations of UBA1 in hematopoietic stem cells appear to cause abnormal inflammation and myeloid predominance in VEXAS syndrome. ... The Transcription Factor STAT4 Controls the Fate of Cytotoxic Innate Lymphocytes. September 26, 2023. ... Early activation of inflammatory pathways in UBA1-mutated hematopoietic stem and progenitor cells in VEXAS. Wu Z, Gao S, Gao Q ... The researchers used single-cell transcriptomic analysis to study bone marrow from men with VEXAS syndrome and found both ...

Transforming growth factor beta (TGF beta) family members are secreted in inactive complexes with a latency-associated peptide ... Transforming Growth Factor beta / physiology * Transforming Growth Factor beta1 * Tumor Cells, Cultured ... We show that TGF beta 1 LAP is a ligand for the integrin alpha v beta 6 and that alpha v beta 6-expressing cells induce ... Transforming growth factor beta (TGF beta) family members are secreted in inactive complexes with a latency-associated peptide ...

... which indicates that pemetrexed triggers ER stress in human ESCC cells. Cyclic AMP-dependent transcription factor ATF-3 (ATF3) ... Pemetrexed activates casp9 and PARP in human esophageal squamous cell carcinoma cells. (A) Eca-109 and (B) EC9706 cells were ... Pemetrexed induces G0/G1 cell cycle arrest in human esophageal squamous cell carcinoma cells. (A) Eca-109 and (B) EC9706 cells ... phase cell cycle arrest and activating the NOXA/Mcl‑1 axis in human esophageal squamous cell carcinoma cells. Oncol Lett 17: ...

Consequently, GE caused the translocation of apoptosis inducing factor to the nucleus leading to the fragmentation of DNA. ... Ginger extract activates caspase-independent paraptosis in cancer cells via ER stress, mitochondrial dysfunction. Publication ... HomePublicationsGinger extract activates caspase-independent paraptosis in cancer cells via ER stress, mitochondrial ... Ginger extract activates caspase-independent paraptosis in cancer cells via ER stress, mitochondrial dysfunction, AIF ...

Platelet-activating factor * The cytokine RANTES (regulated upon activation, normal T cell expressed, and secreted). ... 17] Moreover, nine patients had CD3+CD4+CD8- T cells, three had CD3+CD4-CD8+ cells, three had CD3+CD4-CD8- cells, and two had ... Peripheral blood blast count of , 2% and bone marrow blast cell count , 5% but , 19% of all nucleated cells ... Myeloid cells are demonstrated to be clonal (eg, by detection of clonal cytogenetic abnormality or by demonstration of a very ...

... epithelial neutrophil-activating; GRO, growth related protein; I-TAC, interferon-inducible T-cell alpha chemoattractant. ... CCL, CC chemokine ligand; CXCL, C-X-C motif chemokine ligand; IL, interleukin; INF, interferon; TNF, tumor necrosis factor; MCP ... normal t cell expressed and presumably secreted; MIP, macrophage inflammatory proteins; MIG, monokine-induced γ interferon; ENA ...

... the capability of tumor sphere formation in bladder cancer cells. Mechanically, ATF5 could directly bind to and stimulate the ... activating transcription factor 5). Chromatin immunoprecipitation-qPCR and luciferase activity assays were carried out to ... presenting ATF5 as a prognostic factor or potential therapeutic target for preventing recurrence in BLCA. ... 1 , Cancer Cell International. Fig. 1. From: Activating transcription factor 5 (ATF5) promotes tumorigenic capability and ...

Hepatocyte nuclear factor 3 activates transcription of thyroid transcription factor 1 in respiratory epithelial cells. In: ... Hepatocyte nuclear factor 3 activates transcription of thyroid transcription factor 1 in respiratory epithelial cells. / Ikeda ... Hepatocyte nuclear factor 3 activates transcription of thyroid transcription factor 1 in respiratory epithelial cells. ... Hepatocyte nuclear factor 3 activates transcription of thyroid transcription factor 1 in respiratory epithelial cells. ...

2007) AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat Rev Mol Cell Biol 8:774-785. ... This could include the synthesis of proteins, like CREB, that act as retrograde signaling factors from the site of injury to ... Like NCLS, MK8722 activates AMPK in many cell types but has not previously been tested on DRG neurons. DRGs were cultured from ... 2005) AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 1:15- ...

Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells. Hepatology. 2010;52(1):291-302. ... Cell culture supernatant from activated monocytes or RAW264.7 cells were collected, centrifuged to remove potential cell debris ... Bile acid-activated macrophages promote biliary epithelial cell proliferation through integrin αvβ6 upregulation following ... Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice. Hepatology. 2012;55(4): ...

Study: Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells. Image Credit: ... The plasma deficient factors from coagulation factors like FI, FII, FV, FVII, FVIII, FX, FIX, FXI, FXII, FXIII, vWF, protein S ... The baculovirus-insect cell expression system-insect cells used in conjunction with the baculovirus expression vector system ( ... Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells. Blood Adv 2022; ...

Solution structure of the TIG domain from Human Nuclear factor of activated T-cells, cytoplasmic 4. ... Solution structure of the TIG domain from Human Nuclear factor of activated T-cells, cytoplasmic 4 ...

A Gene Activated in Mouse 3T3 Cells by Serum Growth Factors Encodes a Protein with Zinc Finger Sequences. Contributor(s):. ... 3T3 Cells. Zinc Fingers. Genre(s):. Archival Materials. Articles. Copyright:. This item may be under copyright protection; ...

Soluble factors from stellate cells induce pancreatic cancer cell proliferation ,i,via,/i, Nrf2-activated metabolic ... Soluble factors from stellate cells induce pancreatic cancer cell proliferation ,i,via,/i, Nrf2-activated metabolic ...

Cepharanthine suppresses osteoclast formation by modulating the nuclear factor-κB and nuclear factor of activated T-cell ... Cepharanthine suppresses osteoclast formation by modulating the nuclear factor-κB and nuclear factor of activated T-cell ...

Patients in whom both of these factors were present had a significantly worse RFS when compared to those with one or none. ... We attempt to study such factors that can help identify patients at a higher risk of relapse or death. This retrospective study ... Univariate analysis showed that red blood cell (RBC) transfusion dependence (HR 9.02, 95% CI 4.0-20.35), platelet transfusion ... Factors predicting allogeneic hematopoietic cell transplantation (HCT) outcomes in myelofibrosis in the early post-HCT period ...