4-aminobiphenyl N-acetyltransferase, acetyl CoA-arylamine N-acetyltransferase, 2-naphthylamine N-acetyltransferase, arylamine ... arylamine N-acetyltransferase. Other names in common use include arylamine acetylase, beta-naphthylamine N-acetyltransferase, ... N-acetyltransferase, p-aminosalicylate N-acetyltransferase, serotonin acetyltransferase, and serotonin N-acetyltransferase. As ... an arylamine N-acetyltransferase (EC 2.3.1.5) is an enzyme that catalyzes the chemical reaction acetyl-CoA + an arylamine ⇌ {\ ...
Crystal Structure of Mesorhizobium Loti Arylamine N-acetyltransferase 1 In Complex With CoA ... Insight into cofactor recognition in arylamine N-acetyltransferase enzymes: structure of Mesorhizobium loti arylamine N- ... Arylamine N-acetyltransferase. A, B. 312. Mesorhizobium japonicum MAFF 303099. Mutation(s): 1 Gene Names: mlr4870. EC: 2.3.1.5 ... Arylamine N-acetyltransferases (NATs) are xenobiotic metabolizing enzymes that catalyze the acetyl-CoA-dependent acetylation of ...
"Arylamine N-Acetyltransferase" by people in this website by year, and whether "Arylamine N-Acetyltransferase" was a major or ... However, arylamine N-acetyltransferase should not be confused with the enzyme ARYLALKYLAMINE N-ACETYLTRANSFERASE which is also ... "Arylamine N-Acetyltransferase" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Arylamine N-Acetyltransferase" by people in Profiles. ...
All three exhibited diminished activity towards (MOUSE)NAT2-specific arylamines but were more active against hydrazines than ... NAT1*1 and analysed its substrate specificity using a panel of arylamines and hydrazines. To understand how specific residues ... Background: The mouse has three arylamine N-acetyltransferase genes, (MOUSE)Nat1, (MOUSE)Nat2 and (MOUSE) Nat3. These are ... Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by ...
Arylamine N-Acetyltransferase / chemistry * Arylamine N-Acetyltransferase / genetics * Arylamine N-Acetyltransferase / ... The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland Recent Prog ... arylalkylamine N-acetyltransferase, AA-NAT, E.C. 2.3.1.87). In all vertebrates, enzyme activity is high at night. This reflects ... involved in melatonin synthesis in the pineal gland-the melatonin rhythm-generating enzyme-serotonin N-acetyltransferase ( ...
Arylamine N-Acetyltransferase / metabolism * Cytochrome P-450 Enzyme System / metabolism * Enterohepatic Circulation ...
TPA_inf: Coccidioides immitis nat1 gene for arylamine N-acetyltransferase 1, str... TPA_inf: Coccidioides immitis nat1 gene for ... TPA_inf: Coccidioides immitis nat1 gene for arylamine N-acetyltransferase 1, strain RS, exons 1-2. GenBank: BN001384.1 ... arylamine N-acetyltransferase 1, strain RS, exons 1-2. gi,300431508,tpe,BN001384.1, ...
... was arylamine N-acetyltransferase-1 (NAT-1), a Phase II drug-metabolizing enzyme. NAT-1 overexpression in clinical breast ... Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide ... Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide ... Arylamine N-Acetyltransferase, Breast, Breast Neoplasms, Cell Division, Cell Survival, Drug Resistance, Neoplasm, Etoposide, ...
Arylamine N-acetyltransferases (NATs) are a family of enzymes found in eukaryotes and prokaryotes. While the precise endogenous ... Arylamine N-acetyltransferases (NATs) are a family of enzymes found in eukaryotes and prokaryotes. While the precise endogenous ... Novel small-molecule inhibitors of arylamine N-acetyltransferases: drug discovery by high-throughput screening. ... Novel small-molecule inhibitors of arylamine N-acetyltransferases: drug discovery by high-throughput screening. ...
Genetic polymorphisms of arylamine N-acetyltransferases 1 and 2 and the likelihood of developing pediatric acute lymphoblastic ...
Title: Arylamine N-acetyltransferases in mycotoxigenic and related fungi of agricultural significance Author. KARAGIANNI, ELENI ... Arylamine N-acetyltransferases in mycotoxigenic and related fungi of agricultural significance. In: Proceedings of the 5th ... International Workshop on the Arylamine N-Acetyltransferases, September 1-3, 2010, Paris, France. p. 16.. Interpretive Summary: ...
Wang, D. Y., Yeh, C. C., Lee, J. H., Hung, C. F., and Chung, J. G. Berberine inhibited arylamine N-acetyltransferase activity ... Arylamine N-acetyltransferase 1: a novel drug target in cancer development. Pharmacol Rev 2012;64(1):147-65. View abstract. ... Inhibitory actions of berberine on growth and arylamine N-acetyltransferase activity in strains of Helicobacter Pylori from ... Effects of berberine on arylamine N-acetyltransferase activity in human colon tumor cells. Am J Chin Med 1999;27(2):265-275. ...
A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq] ... This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. ...
Pharmacogenetics of the Human Arylamine N-Acetyltransferases Pharmacology (September,2000). Improvement of Water-Soluble ...
N-acetyltransferase 1,OTTHUMP00000122488,arylamide acetylase 1 (N-acetyltransferase 1),arylamine N-acetyltransferase 1 ... This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human geneome, and is orthologous to the mouse and rat ... The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine ...
Arylamine n-acetyltransferase activity. Specific Function. Controls the night/day rhythm of melatonin production in the pineal ...
The activity of H. pylori arylamine N-acetyltransferase was inhibited in the presence of DAS and DADS, suggesting that these ... 1998). Effects of garlic compounds diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity in strains ...
Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix ... Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix ... Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix ... Effect arylamine N-acetyltransferase 1 on morphology, adhesion, migration, and invasion of MDA-MB-231 cells: role of matrix ...
Increased frequency of wild-type arylamine-N-acetyltransferase allele NAT2*4 homozygotes in Portuguese patients with colorectal ...
Recently, two N-acetyltransferase genes, Nat-1 and Nat-2, were cloned from rapid (C57BL/6J) and slow (A/J) acetylator mouse ... N-Acetylation plays an important role in the metabolism of a wide variety of hydrazine drugs and arylamine drugs and ... Mice have a similar genetic polymorphism in N-acetyltransferase activity and have been used as models of the human polymorphism ... Cloned mouse N-acetyltransferases: enzymatic properties of expressed Nat-1 and Nat-2 gene products. ...
The Xenobiotic-Metabolizing Enzymes Arylamine N-Acetyltransferases in Human Lens Epithelial Cells: Inactivation by Cellular ...
Arylamine N-acetyltransferase 2 (NAT2) catalyzes the addition of an acetyl group from acetyl-CoA to a terminal nitrogen on ... Cascorbi I, Drakoulis N, Brockmoller J, Maurer A, Sperling K, Roots I. Arylamine N-acetyltransferase (NAT2) mutations and their ... Variation of the N-Acetyltransferase 2 Gene in a Romanian and a Kyrgyz Population Sylvia Rabstein; Sylvia Rabstein ... Lin HJ, Han Ch, Lin BK, Hardy S. Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2 ...
Arylamine N-acetyltransferases--from drug metabolism and pharmacogenetics to identification of novel targets for ... Reduction of N-acetylation of PABA can be achieved by saturation or substrate inhibition of N-acetyltransferase I (26). In ... PABA also undergoes acetylation within the cellular cytosol via N-acetyltransferase I to form para-acetamidobenzoic acid (PAABA ... Given the high affinity of N-acetyltransferase for PABA, we hypothesized that administration of 1 mg nonradiolabeled PABA just ...
Structure of arylamine N-acetyltransferase from Mycobacterium tuberculosis determined by cross-seeding with the homologous ...
Role of arylamine N-acetyltransferases (NAT) in development of metabolic syndrome. [email protected]. 502-852-0686 ...
The Arylamine N-acetyltransferase Gene Nomenclature Committee:. Dr. Sotiria Boukouvala. Department of Molecular Biology & ...