*  RCSB PDB - Protein Feature View - Arachidonate 5-lipoxygenase - P09917 (LOX5 HUMAN)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
  http://www.rcsb.org/pdb/protein/E5FPY8
*  Arachidonate 5-lipoxygenase - Wikipedia
Arachidonate 5-lipoxygenase, also known as ALOX5, 5-lipoxygenase, 5-LOX, or 5-LO, is a non-heme iron-containing enzyme (EC 1.13 ... "Alox5 - arachidonate 5-lipoxygenase". WikiGenes. Fahel JS, de Souza MB, Gomes MT, Corsetti PP, Carvalho NB, Marinho FA, de ... Arachidonate 5-lipoxygenase is a member of the lipoxygenase family of enzymes. It transforms essential fatty acids (EFA) ... Arachidonate 5-Lipoxygenase at the US National Library of Medicine Medical Subject Headings (MeSH) Human ALOX5 genome location ...
  https://en.wikipedia.org/wiki/Arachidonate_5-lipoxygenase
*  Arachidonate 5-lipoxygenase inhibitor - Wikipedia
Lipoxygenase inhibitors at the US National Library of Medicine Medical Subject Headings (MeSH) MeSH list of agents 82016859. ... Arachidonate 5-lipoxygenase inhibitors are compounds that slow or stop the action of the arachidonate 5-lipoxygenase (5- ... lipoxygenase or 5-LOX) enzyme, which is responsible for the production of inflammatory leukotrienes. The overproduction of ... Arachidonate 5-lipoxygenase ...Specific function: Catalyzes the first step in leukotriene biosynthesis, and thereby plays a ...
  https://en.wikipedia.org/wiki/Arachidonate_5-lipoxygenase_inhibitor
*  Arachidonate 5-lipoxygenase elisa and antibody
Recombinant Protein and Arachidonate 5-lipoxygenase Antibody at MyBioSource. Custom ELISA Kit, Recombinant Protein and Antibody ... Arachidonate 5-lipoxygenase. Arachidonate 5-lipoxygenase ELISA Kit. Arachidonate 5-lipoxygenase Recombinant. Arachidonate 5- ... lipoxygenase Antibody. Also known as Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase).. Catalyzes the first step in ... Below are the list of possible Arachidonate 5-lipoxygenase products. If you cannot find the target and/or product is not ...
  https://www.mybiosource.com/protein_family.php?root=arachidonate-5-lipoxygenase
*  Arachidonate 5-lipoxygenase-activating protein
THE 5-LOX interface involving the four cysteines 159, 300, 416 and 418 is important for the translocation to the nuclear ... Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein.. 26159646. 2015. Variants in the ... Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5- ... lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this ...
  https://pharos.nih.gov/idg/targets/P20292
*  Antileukotriene - Wikipedia
An antileukotriene is a drug which functions as a leukotriene-related enzyme inhibitor (arachidonate 5-lipoxygenase) or ... "Inhibition of five lipoxygenase activating protein (FLAP) by MK-886 decreases atherosclerosis in apoE/LDLR-double knockout mice ... Arachidonate 5-lipoxygenase ...Specific function: Catalyzes the first step in leukotriene biosynthesis, and thereby plays a ... Examples of 5-LOX inhibitors include drugs, such as meclofenamate sodium and zileuton. Some chemicals found in trace amounts in ...
  https://en.wikipedia.org/wiki/Antileukotriene
*  Amlexanox - Wikipedia
The 5% preparation for patient use is an adherent beige paste,[3][8] and it is also available in some countries as a tablet ... InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21) Y ... 7. Synthesis of Antiallergic 5-Oxo-5H-\1]benzopyrano\2,3-b]pyridines". Journal of Medicinal Chemistry. 28 (5): 559-68. doi: ... A 2011 review found a one-week supply of amlexanox 5% paste to cost $30.[6] ...
  https://en.wikipedia.org/wiki/Amlexanox
*  Montelukast - Wikipedia
In children 6 to 14 years of age the usual dosage is one 5 mg chewable tablet a day. The dose is preferably taken in the ... The Mont in Montelukast stands for Montreal, the place where Merck (MSD) developed the drug.[5] ... Montelukast is administered as montelukast sodium, with 5.2 mg of montelukast sodium being equivalent to 5 mg of montelukast.[8 ...
  https://en.wikipedia.org/wiki/Montelukast
*  Gene Expression Literature Summary - MGI
arachidonate 5-lipoxygenase. MGI:87999 5 matching records from 5 references.. Summary by Age and Assay: Numbers in the table ...
  http://www.informatics.jax.org/gxdlit/marker/MGI:87999
*  KEGG BRITE: KEGG Orthology (KO) - Falco peregrinus (peregrine falcon)
101914238 ALOX5; arachidonate 5-lipoxygenase 101917252 LTA4H; leukotriene A4 hydrolase 101917253 leukotriene C4 synthase-like ... arachidonate 5-lipoxygenase [EC:1.13.11.34] K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6] K00807 LTC4S; leukotriene-C4 ... 101910798 GGT5; gamma-glutamyltransferase 5 101910629 GGT1; gamma-glutamyltransferase 1 101911072 GPX2; glutathione peroxidase ... 5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14] K00432 gpx ...
  http://www.genome.jp/kegg-bin/get_htext?fpg00001+101919862
*  Aminosalicylic Acid - DrugBank
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some ... Sircar JC, Schwender CF, Carethers ME: Inhibition of soybean lipoxygenase by sulfasalazine and 5-aminosalicylic acid: a ... Allgayer H, Eisenburg J, Paumgartner G: Soybean lipoxygenase inhibition: studies with the sulphasalazine metabolites N- ... 2006 Dec;5(12):993-6. [PubMed:17139284] *Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug ...
  https://www.drugbank.ca/drugs/DB00233
*  biomedexperts - Free People Search - Yasni.com
Marija Rakonjac Ryge - research profile on BiomedExperts: Marija Rakonjac Ryge - research profile on BiomedExperts:Arachidonate ...
  http://www.yasni.com/biomedexperts/free+people+search
*  Gout | Healing Centers | Healing Centers | Healthways, Inc.
Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase. Biochem Biophys Res Commun. 1983;116:612-618.. 22. Luerti M, ... 1980 Nov;96(5):783-9.. 25. Busse WW, Kopp DE, Middleton E Jr. Flavonoid modulation of human neutrophil function. J Allergy Cin ... 5. Wortmann RL, Kelley WN. Gout and hyperuricemia. In: Harris ED Jr, Budd RC, Genovese MC, et al, eds. Kelley's Textbook of ... New York: Scientific American, 1986:9:IV-1-5,15:IX-1-11.. 29. Chantre P, Cappelaere A, Lebian D, et al. Efficacy and tolerance ...
  http://www.wholehealthmd.com/Main/healing-centers/130.aspx?page=multivitamin
*  Human Metabolome Database: Showing metabocard for Linoleic acid (HMDB0000673)
Arachidonate 15-lipoxygenase B. General function:. Involved in metal ion binding. Specific function:. Converts arachidonic acid ... Arachidonate 15-lipoxygenase. General function:. Involved in metal ion binding. Specific function:. Converts arachidonic acid ... Also acts on C-12 of arachidonate as well as on linoleic acid. Gene Name:. ALOX15. Uniprot ID:. P16050 Molecular weight:. ... Arachidonate 5-lipoxygenase. General function:. Involved in metal ion binding. Specific function:. Catalyzes the first step in ...
  http://www.hmdb.ca/metabolites/HMDB00673
*  Human Metabolome Database: Showing metabocard for 4'-Hydroxydiclofenac (HMDB0013974)
4. Arachidonate 5-lipoxygenase. General function:. Involved in metal ion binding. Specific function:. Catalyzes the first step ... Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role ... 2005 May;50(5):879-81. [PubMed:15906762 ] *Singh N, Jabeen T, Sharma S, Somvanshi RK, Dey S, Srinivasan A, Singh TP: Specific ... 2003;153(5-6):95-9. [PubMed:12705061 ] *Chavez ML, DeKorte CJ: Valdecoxib: a review. Clin Ther. 2003 Mar;25(3):817-51. [PubMed: ...
  http://www.hmdb.ca/metabolites/HMDB13974
*  N-hydroxy-N-(2,3-dihydro-6-phenylmethoxy-3-benzofuranyl)urea Summary Report | CureHunter
... a selective 5-lipoxygenase inhibitor; structure given in first source ... 06/01/1995 - "Pharmacological characterization of SB 202235, a potent and selective 5-lipoxygenase inhibitor: effects in models ...
  http://www.curehunter.com/public/keywordSummaryC094196-N-hydroxy-N--2-3-dihydro-6-phenylmethoxy-3-benzofuranyl-urea.do
*  Novel 5-Lipoxygenase Inhibitors in Inflammation and Asthma | SpringerLink
The discovery of mammalian lipoxygenases which convert arachidonic acid to oxygenated products with potent inflammatory and ... Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: I. Biochemical assessment in vitro and ex ... Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: II. Effects on bronchial anaphylaxis in ... Leukotriene B4, along with some of the mono-hydroxy lipoxygenase products is chemotactic and it has been suggested that LTB4 ...
  https://link.springer.com/chapter/10.1007/978-1-4684-7938-6_22
*  1,25-Dihydroxyvitamin D3 Is an Autonomous Regulator of the Transcriptional Changes Leading to a Tolerogenic Dendritic Cell...
Interestingly, the expression profile of arachidonate 5-lipoxygenase (ALOX5; in cluster 6 in Fig. 3⇑) suggested that genes ... 5⇑C).. We next reasoned that if the effect of 1,25-vitD is really independent of differentiation, it should induce these three ... 5⇑C). However, previous studies revealed that 1,25-vitD can be generated endogenously (37, 38, 39, 40). We therefore sought to ... A member of this family is the vitamin D receptor (VDR). A number of studies (4, 5, 6, 7, 8, 9, 10) provided evidence that the ...
  http://www.jimmunol.org/content/182/4/2074.long
*  Search
ALOX5 (arachidonate 5-lipoxygenase)  Banerjee, S; Tuncay, S (Jean-Loup Huret (Editor-in-Chief) ; INIST-CNRS (Publisher), 2006) ...
  http://documents.irevues.inist.fr/handle/2042/32136/discover?filtertype=subject&filter_relational_operator=equals&filter=Genes+Section
*  Genetic Basis of Atherosclerosis: Part II | Circulation
Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis. N Engl J Med. 2004; 350: 29-37. ... The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet. 2004; 36: 233- ... Genetic variations in 5-LO have been shown to contribute to the variable response to antileukotriene drugs in asthma (Figure 1 ... Common variations in the genes for PDE4D, lymphotoxin-α, 5-LO, 5-LO-activating protein, and others discussed in Part I of this ...
  http://circ.ahajournals.org/content/110/14/2066.long
*  anti-FLAP antibody, Internal | GeneTex
... arachidonate 5-lipoxygenase-activating protein) for IHC-P, WB. Anti-FLAP pAb (GTX89246) is tested in Human samples. 100% Ab- ... arachidonate 5lipoxygenaseactivating, MK-886-binding protein, FLAP / ALOX5AP (internal), ALOX5AP, five-lipoxygenase activating ... arachidonate 5-lipoxygenase-activating protein. Background. Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). ... MK886binding protein, FLAP, arachidonate 5-lipoxygenase-activating protein, arachidonate5lipoxygenaseactivating, ...
  http://www.genetex.com/FLAP-ALOX5AP-antibody-Internal-GTX89246.html
*  Allergies, Respiratory | Grand Strand Health
Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase. Biochem Biophys Res Commun. 1983;116:612-618. ... 2-5 A particular flavonoid, quercetin , seems to be one of the most active. 6-11 Many texts on natural medicine claim that ... 5 Middleton E Jr. Effect of flavonoids on basophil histamine release and other secretory systems. Prog Clin Biol Res. 1986;213: ...
  https://grandstrandmed.com/hl/?/21414/Seasonal-Allergy&com.dotmarketing.htmlpage.language=1
*  Role of Lipoxygenase Metabolites of Arachidonic Acid in Enhanced Pulmonary Artery Contractions of Female Rabbits | Hypertension
Arachidonate 15-lipoxygenase (w-6 lipoxygenase) from human leukocytes. J Biol Chem. 1988;263:5328-5332. ... Related expression of arachidonate 12- and 15-lipoxygenases in animal and human lung tissue. Am J Physiol. 1991;261:L399-L405. ... Role of Lipoxygenase Metabolites of Arachidonic Acid in Enhanced Pulmonary Artery Contractions of Female Rabbits. Sandra L. ... Expression of 15-lipoxygenase type-1 in human mast cells. Biochim Biophys Acta. 2007;1771:1156-1165. ...
  http://hyper.ahajournals.org/content/57/4/825.long
*  Transcriptome profiling of gene expression during immunisation trial against Fasciola hepatica: identification of genes and...
Arachidonate 5-lipoxygenase. ANOVA: Analysis of variance. ANXA1: Annexin A1. BRCA2: Breast cancer type 2 ... 2004;5(10):R80.View ArticlePubMedPubMed CentralGoogle Scholar. *. Risueno A, Fontanillo C, Dinger ME, De Las RJ. GATExplorer: ... 2000;16(5):202-9.View ArticlePubMedGoogle Scholar. *. Hagan P, Wilkins HA, Blumenthal UJ, Hayes RJ, Greenwood BM. Eosinophilia ... 2012;9(7):671-5.View ArticlePubMedGoogle Scholar. *. Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B ...
  https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-017-2205-3
*  Differentiation of two types of mobilized peripheral blood stem cells by microRNA and cDNA expression analysis | Journal of...
2007, 4: 5-10.1186/1742-4690-4-5.PubMed CentralView ArticlePubMedGoogle Scholar. ... The probes were 5' amine modified and printed in duplicate in the Immunogenetics Section of the DTM on CodeLink activated ... However, umbilical cord blood has been found to be especially rich in HSCs [5] and HSCs have been found in the peripheral blood ... When the expression of all the miRNAs in the miR-17-92 cluster (n = 7) were compared between HSCs and PBLs, 5 of the 7 were ...
  https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-6-39