Arabinofuranosylcytosine triphosphate - Wikipedia
Arabinofuranosylcytosine triphosphate,Arabinofuranosyluracil Suppliers & Manufacturers
... triphosphate, Cytosine arabinoside 5-triphosphate, 1-beta-D-Arabinofuranosylcytosine triphosphate, Cytosine, 1-beta-D- ... Arabinofuranosylcytosine triphosphate (5 suppliers). IUPAC Name: [[(2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4- ... beta-D-Arabinofuranosyl 5-triphosphate, D-Arabinose, 5-(tetrahydrogen triphosphate), D-Arabinose,5-(tetrahydrogen triphosphate ... Synonyms: Arabinose 5-triphosphate, AG-G-94955, AC1L2QDI, D-Arabinose 5-triphosphate, Ara-5-P(3), CTK5D9574, ...
Chinese hamster ovary cell mutants resistant to DNA polymerase inhibitors - I. Isolation and biochemical genetic...
Molecular Weight - McMaster Experts
Variation in sensitivity of DNA synthesis to ara-C in acute myeloid leukaemia. - Department of Oncology
Arabinofuranosylcytosine Triphosphate, Bone Marrow, Cells, Cultured, Cytarabine, DNA, Neoplasm, Dose-Response Relationship, ...
Cytidine Monophosphate | Profiles RNS
Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias |...
clofarabine, cytarabine, leukemia, acute, arabinofuranosylcytosine triphosphate, c-reactive protein, cyclic amp receptor ... Quantitation of 1-β-D-arabinofuranosylcytosine 5′-triphosphate in the leukemic cells from bone marrow and peripheral blood of ... Cellular pharmacology of ara-CTP and clofarabine triphosphate suggested that clofarabine triphosphate accumulation resulted in ... Triphosphates were separated on an anion-exchange Partisil-10 SAX column (Waters, Milford, MA) using HPLC as described in ...
CANCER CHEMOTHERAPY I and 2015 Michael Lea
In addition there is incorporation of 5 -fluorouridine triphosphate into RNA. 3. RESISTANCE: Multiple mechanisms including ... CYTARABINE (Cytosine arabinoside, ara-C) 1. CHEMICAL NATURE: 1 -beta-arabinofuranosylcytosine (analog of the pyrimidine ... nucleoside, cytosine, with substitution of arabinose for ribose) 2. MECHANISM OF ACTION: The triphosphate metabolite inhibits ...
CCCC 1963, Volume 28, Issue 2, Abstracts pp. 469-480, Articles by the same authors | Collection of Czechoslovak Chemical...
Synthesis of guanylyl-(3→5)-uridylyl-(3→5)-arabinofuranosyluracil and guanylyl-(3→5)-uridylyl-(3→5)-arabinofuranosylcytosine ... The synthesis of 6-azauridine-5 triphosphate. 1963, Vol. 28, Issue 1, pp. 241-244 [Abstract] ... One-step synthesis of 1-β-D-arabinofuranosylcytosine. 1977, Vol. 42, Issue 5, pp. 1588-1594 [Abstract] ... Synthesis of 1-β-D-arabinofuranosylcytosine. 1974, Vol. 39, Issue 11, pp. 3100-3108 [Abstract] ...
Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of...
Protein activation and expression were analysed by western blotting, deoxyribonucleoside triphosphate levels by HPLC, ... Determination of deoxyribonucleoside triphosphates. The extraction of cellular dNTPs was performed according to a method ... synergistic antitumor activity with arabinofuranosylcytosine. Int J Oncol 31 (5): 1261-1266 ... Protein activation and expression were analysed by western blotting, deoxyribonucleoside triphosphate levels by HPLC, ...
Arabinonucleosídeos/toxicidade
The combination index revealed antagonism between forodesine and ara-G. The intracellular production of ara-G triphosphate was ... Safety assessment of 4-thio-beta-D-arabinofuranosylcytosine in the beagle dog suggests a drug-induced centrally mediated ... The intracellular concentration of the triphosphate metabolite of cytarabine was reduced to 1/10, and that of clofarabine was ... Plasma clofarabine levels generated clofarabine triphosphate accumulation, which resulted in an increase in ara-CTP in the ...
MMTB
4-thio-beta-D-arabinofuranosylcytosine + UTP <=> UDP + 4-thio-beta-D-arabinofuranosylcytosine_5-phosphate 2.7.1.74 ... dATP + UTP <=> dAMP + uridine_3-diphosphate_5-triphosphate 2.7.6.4 nucleotide diphosphokinase - ... UTP + cytosine_arabinoside <=> UDP + 1-beta-D-arabinofuranosylcytosine_5-phosphate 2.7.1.74 deoxycytidine kinase - ... 3.6.1.15 nucleoside-triphosphate phosphatase 3.6.1.28 thiamine-triphosphatase 3.6.1.39 thymidine-triphosphatase 3.6.1.45 UDP- ...
Диссертация на тему «Процессы модуляции апоптоза клеток К562 при обработке индукторами эритроидной и миелоидной дифференцировки...
Whitman S.P., Civoli F., Daniel L.W. Protein kinase С beta2 activation by 1-beta-D-arabinofuranosylcytosine is antagonistic to ... Reynolds E.C., Harris A.W., Finch L.R. Deoxyribonucleoside triphosphate pools and differential thymidine sensitivities of ... Fram R, Kufe D. DNA strand breaks caused by inhibitors of DNA synthesis: l-(5-D-arabinofuranosylcytosine and aphidicolin // ... Wang S., Wang Z., Grant S. Bryostatin 1 and UCN-01 potentiate 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human ...
Publications
5-ethynyl-1-beta-d-arabinofuranosylcytosine (eac) was prepared from 1-(2,3,5-tri-o-acetyl-beta-d-arabinofuranosyl)cytosine by ... characterization of a herpes simplex virus type 2 deoxyuridine triphosphate nucleotidohydrolase and mapping of a gene ... 1) the accumulation of guanosine analog-triphosphates in infected cells, which is .... 1987. 2823702. ... the herpes simplex virus type 2 (hsv-2)-induced deoxyuridine triphosphate nucleotidohydrolase (dutpase) was purified ...
CCCC 1956, Volume 21, Issue 4, Abstracts pp. 1035-1042, Articles by the same authors | Collection of Czechoslovak Chemical...
Synthesis of guanylyl-(3→5)-uridylyl-(3→5)-arabinofuranosyluracil and guanylyl-(3→5)-uridylyl-(3→5)-arabinofuranosylcytosine ... The synthesis of 6-azauridine-5 triphosphate. 1963, Vol. 28, Issue 1, pp. 241-244 [Abstract] ... 5-Triphosphates of 3-deoxyribonucleosides. 1973, Vol. 38, Issue 4, pp. 1173-1178 [Abstract] ...
Publications | Molecular Virology
EurekaMag Full Text Articles Chapter 43410
Murthy, V.K.; Stiles, M.R.; Shipp, J.C. 1983: Inhibition by adenosine triphosphate of heart microsomal neutral lipase activity ... Hawtrey, A.O.; Scott-Burden, T.; Jones, P.; Robertson, G. 1973: Inhibition by 1-beta-D-arabinofuranosylcytosine of the ... Wickremasinghe, R.G.; Hoffbrand, A.V. 1983: Inhibition by aphidicolin and dideoxythymidine triphosphate of a multienzyme ...
Prices
2 -Deoxy-2 -fluoroadenosine 5 -Triphosphate. 10 µmol. 134. 141. 104-02. 2 -Deoxy-2 -fluorocytidine 5 -Triphosphate. 10 µmol. ... 1-(2-Deoxy-2-fluoro- -D-arabinofuranosyl)cytosine hydrochloride (2 -FANA-C). 1 g. 779. 820. ... 2 -Deoxy-2 -fluoroguanosine 5 -Triphosphate. 10 µmol. 134. 141. 104-04. 2 -Deoxy-2 -fluorouridine 5 -Triphosphate. 10 µmol. 134 ... Modified Purine Nucleoside 5-Triphosphates. 107-01. 2-Deoxy-2,2-difluoroadenosine 5 -triphosphate, tetra-lithium salt. 10 ...