An antiproliferative genetic screening identifies a peptide aptamer that targets calcineurin and up-regulates its activity. ...

... The use of nanocarriers within resistive pulse sensing, RPS, aids ... A simple displacement aptamer assay on resistive pulse sensor for small molecule detection by: Rhushabh Maugi, et al. Published ... The chemistry and biochemistry of the sulfhydryl group in amino acids, peptides and protein / (by) Mendel Friedman. by: ... Aptamer beacon-based single-step fluorescence method for rapid detection of bacteria and antimicrobial resistance by: ...

M13 phage displaying an in vivo biotinylatable peptide (AviTag) genetically fused to the phage tail protein pII … ... We introduce the modification of bacteriophage particles with aptamers for use as bioanalytical reporters, and demonstrate the ... Aptamer-Phage Reporters for Ultrasensitive Lateral Flow Assays Anal Chem. 2015 Dec 1;87(23):11660-5. doi: 10.1021/acs.analchem. ... M13 phage displaying an in vivo biotinylatable peptide (AviTag) genetically fused to the phage tail protein pIII were used as ...

An automated pipeline for simulation of DNA aptamers complexed with small molecules and short peptides Jan 26, 2022 7 min read ... E2EDNA 2.0 takes in a DNA aptamer sequence in FASTA format, and optionally a short peptide or other small molecule, and returns ... An automated pipeline for simulation of DNA aptamers complexed with small molecules and short peptides.. Michael Kilgour, Tao ... free aptamer. → fold the aptamer in MMB and run extended MD sampling to identify a representative, equilibrated 2D and 3D ...

Ames TD, Breaker RR (January 2011). "Bacterial aptamers that selectively bind glutamine". RNA Biol. 8 (1): 82-89. doi:10.4161/ ... Downstream-peptide RNAs are found upstream of short open reading frames (ORFs) that are predicted to encode short peptides ( ... Possible candidates to be regulated by the Downstream-peptide motif are genes that frequently carry the Downstream-peptide ... and their structural similarity to Downstream-peptide RNAs in turn suggests that Downstream-peptide RNAs are also riboswitches ...

Isolation of peptide aptamers that inhibit intracellular processes  Blum, Jonathan H.; Dove, Simon L.; Hochschild, Ann; ... Isolation of a novel basic FGF-binding peptide with potent antiangiogenetic activity  Wu, Xiaoping; Yan, Qiuxia; Huang, Yadong ...

Peptide aptamers: tools to negatively or positively modulate HSPB1(27) function. Gibert B, Simon S, Dimitrova V, Diaz-Latoud C ...

By their targeting of short, linear motif type of interactions, peptide aptamers have joined nucleic acid aptamers for use in ... We propose that peptide aptamers can provide a very [...] Read more. The smooth identification and low-cost production of ... We propose that peptide aptamers can provide a very useful and new alternative for interfering with protein-protein ... antibacterial peptides, annexin 1-derived peptides, chemokine variants, the neuropeptides, vasoactive intestinal peptide (VIP) ...

Roger Brent Peptide aptamers Molecular Sciences Institute, 1999 Broader term: aptamers peptide arrays: Steve Fodor and ... Narrower terms: photoaptamers, Functional genomics Protein technologies peptide aptamer; Genomic technologies SELEX, ... Peptide Mass Fingerprinting PMF: A means of protein identification, using mass spectrometry peptide sequencing: How is this ... peptide aptamers: Engineered protein molecules selected from combinatorial libraries, [used] to dissect the function of ...

Title: Peptide aptamers define distinct EB1- and EB3-binding motifs and interfere with microtubule dynamics. ... Aptamers binding to human EB1 and EB3, which have sequence requirements similar to but distinct from each other and from ...

23. Interactions of in vitro selected fluorogenic peptide aptamers with calmodulin Author(s): Manandhar, Yasodha; Wang, Wei; ... 58. Selective improvement of peptides imaging on tissue by supercritical fluid wash of lipids for matrix-assisted laser ... 37. Regulation of photosensitisation processes by an RNA aptamer Author(s): Tran Thi Thanh Thoa; Minagawa, Noriko; Aigaki, ...

This review aims to analyze various peptide-copper complexes and the mechanism of their action. ... peptides and proteins) playing an essential role in many biological and physiological pathways in the human body. The resulting ... Anti-prion activity of an RNA aptamer and its structural basis. Nucleic Acids Res. 2013, 41, 1355-1364. [Google Scholar] [ ... A copper-peptide complex consisting of a domain GGH (Gly-Gly-His) able to efficiently bind copper ions and the peptide (MPP) ...

Development of Peptide Aptamers as tools to dissect signal transduction.. Gordon-Weeks, P. ...

Nucleic acid and peptide aptamers as potential antiviral drugs </p> - Host-directed, antibiotic-adjuvant ...

... and aptamer have been extensively applied for preclinical studies. Therapeutic drug or gene is incorporated into nanoparticles ... Peptide is an important class of ligand used for molecular imaging [62]. Compared to small molecules, peptide has many ... Nanoparticles modified with small molecule, peptide, antibody, and aptamer have been extensively applied for preclinical ... Targeted Molecular Imaging Agents Based on Aptamer. Aptamer, single-stranded DNA or RNA oligonucleotides, can bind to their ...

Nucleic acid and peptide aptamers as potential antiviral drugs </p> - Host-directed, antibiotic-adjuvant ...

Amyloid-beta peptide detection via aptamer-functionalized nanowire sensors exploiting single-trap phenomena. Y.Kutovyi et al. ...

Then they flip the whole system to produce MI aptamers or MI peptides that will bind to the natural target. Now with MI PCR and ... Researchers are actively developing MI aptamer and MI peptide drug candidates for disease treatment. Currently, they develop ... MI aptamers and MI peptides are already being developed as therapies for diseases such as cancer. ... To find MI aptamers with therapeutic potential, you can synthesize large numbers of them, pull out those that bind to the ...

RNA aptamers and RNA guides. According to the European Union (EU) legislation, these products can be currently categorized into ... RNA aptamers and RNA guides. According to the European Union (EU) legislation, these products can be currently categorized into ... RNA aptamers. RNA aptamers bind to and inhibit a wide variety of targets (including proteins, peptides, DNAs, RNAs) by virtue ... For both the EU and the USA, the biological origin of the drug matters, so ASOs, siRNA, miRNA, saRNA and aptamers, which are ...

The specific aptamers were screened out and used in direct enzyme-linked aptamer assay (DELAA) for detection of native SAG1 (n- ... The selected aptamers were amplified by PCR and DNA sequencing.. The results showed that the aptamer-2, with the highest ... Delivery of superoxide dismutase by TAT and Abalone peptides for the protection of skin cells against oxidative stress. Arao. ... Direct enzyme-linked aptamer assay (DELAA) for diagnosis of toxoplasmosis by detection of SAG1 protein in mice and humans. ...

Fusion Polypeptides That Inhibit Exocytosis: Fusing Aptamer and Cell-Penetrating Peptide Technologies and Pharmacologies Lee E ... Targeting Effector Memory T Cells with a Selective Peptide Inhibitor of Kv1.3 Channels for Therapy of Autoimmune Diseases ... Elastin Peptides Activate Extracellular Signal-Regulated Kinase 1/2 via a Ras-Independent Mechanism Requiring Both p110γ/Raf-1 ...

LabWrench article Aptamer Kits for Cell Isolation & Flow Cytometry ... Aptamers are oligonucleotides or peptides that bind to a specific target molecule. Aptamers are useful in biotechnological and ... Aptamers are oligonucleotides or peptides that bind to a specific target molecule. Aptamers are useful in biotechnological and ... Incorporating bifunctional aptamer labeled with FITC and biotin the kits allow you to perform cell isolation and flow cytometry ...

Aptamers as Novel Binding Molecules on an Antimicrobial Peptide-Armored Composite Hydrogel Wound Dressing for Specific Removal ... Kaygisiz, K.; Rauch-Wirth, L.; Iscen, A.; Hartenfels, J.; Kremer, K.; Münch, J.; Synatschke, C. V.; Weil, T.: Peptide ... Cm-p5 Peptide Dimers Inhibit Biofilms of Candida albicans Clinical Isolates, C. parapsilosis and Fluconazole-Resistant Mutants ... Optimized peptide nanofibrils as efficient transduction enhancers for in vitro and ex vivo gene transfer. Frontiers in ...

Implementation of anti-apoptotic peptide aptamers in cell and "in vivo" models of Parkinsons disease ...

... aptamers, peptides or others. This gives nanoparticles loaded with APIs the ability to recognize and bind to the diseased sites ... As one example, the field of peptide-based drug conjugates (PDCs) is advancing rapidly. While no PDCs have obtained regulatory ... The goal of this work is to overcome challenges in developing and manufacturing peptide delivery vehicles that meet both ... Among the many challenges that need to be overcome are premature degradation in the body, poor peptide transport over ...

Peptides, Proteins, Enzymes, cDNAs, Aptamers, Adjuvants and ODNs(1465) * IHC/ICC Slides and Lysates for Westerns(357) ...

Peptides, Proteins, Enzymes, cDNAs, Aptamers, Adjuvants and ODNs(1465) * IHC/ICC Slides and Lysates for Westerns(358) ...

Peptides, Proteins, Enzymes, cDNAs, Aptamers, Adjuvants and ODNs(1465) * IHC/ICC Slides and Lysates for Westerns(358) ...

It was shown that a peptide (Aptamer 9) blocked PKM2 in its inactive conformation thereby decreasing cell proliferation even in ...

Aptamers are short oligonucleotide chains that are artificially screened with good specificity and affinity. The Sgc8 aptamer ... PTK7 (N-term) peptide recombinant protein (PTK7) is overexpressed on the acute T-cell leukemia cell line (CCRF-CEM cells), and ... Sgc8 aptamer is light and mostly attached to the tube wall, and its dry film shape is easily dispersed before opening, so it ... Add the shaken Sgc8 aptamer to a BP-PEG solution with a concentration of 100 μg/mL, and mix it with a suitable amount of ...